Apathy in Parkinson Disease: Clinical, Physiopathological and Pharmacological Study

Apathy in Parkinson Disease: Clinical, Physiopathological and Pharmacological Study

Sponsors

Lead sponsor: University Hospital, Grenoble

Collaborator: Institut National de la Santé Et de la Recherche Médicale, France

Source University Hospital, Grenoble
Brief Summary

Apathy has been reported to occur after subthalamic nucleus stimulation (STN-DBS), a treatment of motor complications in advanced Parkinson's disease (PD). It is not known whether postoperative apathy is related to dopamine withdrawal or a side effect of STN DBS. The researchers investigated potential predictors of apathy, and the effect of dopamine agonist treatment.

Overall Status Unknown status
Start Date January 2005
Completion Date June 2011
Primary Completion Date February 2006
Study Type Observational
Enrollment 120
Condition
Eligibility

Sampling method: Probability Sample

Criteria:

Inclusion Criteria:

- Parkinson disease

Exclusion Criteria:

- Mattis scale < 130

- Beck scale > 20

Gender: All

Minimum age: 18 Years

Maximum age: 70 Years

Healthy volunteers: No

Overall Contact

Last name: Krack Paul, MD

Phone: 0476765791

Email: [email protected]

Location
facility status contact Hopital neurologique Broussolle, MD
Location Countries

France

Verification Date

November 2009

Responsible Party

Name title: Délégation à la recherche clinique

Organization: CHU de grenoble

Keywords
Has Expanded Access No
Condition Browse
Study Design Info

Observational model: Cohort

Time perspective: Prospective

Source: ClinicalTrials.gov