Esta página se tradujo automáticamente y no se garantiza la precisión de la traducción. por favor refiérase a versión inglesa para un texto fuente.

Human Fine-motor-skills in Weightlessness: Comparison of a Laboratory and an Everyday-like Context (FINESKILL)

30 de septiembre de 2015 actualizado por: University Hospital, Caen

The human performance during weightlessness was tested in a multiplicity of laboratory experiments during parabolic flights and in space. It is therefore known that human fine motor skills as grasping are affected by the impact of changing gravity levels. However, because everyday life movements differ in several aspects from those done in an experimental lab situation, investigators do not know until know if this kind of movements is altered in the same extend.

Fine motor skills seem to depend on the context in which they are made. Thus, the performance in weightlessness during everyday life could substantially differ from the results given by previous laboratory studies.

This assumption will be tested in the present project, with subjects executing one and the same grasping movement in two different contexts, both in normal gravity conditions and in weightlessness. To that end, the investigators developed a new method which allows comparing the same grasping movements under different conditions.

Descripción general del estudio

Estado

Desconocido

Condiciones

Descripción detallada

Investigations description Subjects sit at a table in front of a 15" computer screen, a centrally located joystick and a sliding lever on the right side. All devices are fixed to the table.

The subjects hand is fitted with six adhesive reflexive markers so that hand movements can be registered from above by two MX-F20 Vicon-Cameras, attached to a table-fixed metal frame. Lever forces are registered by an ATI Nano17 force transducers, lever fore-aft position by an inductive encoder, and eye position by an eye tracker (Tobii T60).

Subjects will perform two different tasks, one representing a typical laboratory (L), one an everyday-like task (E). In task L, a visual stimulus on the screen will prompt subjects to release the joystick, grasp the lever, move it forwards and back, and then return their hand to the joystick. In task E, subjects will use the joystick in a computer game ("spider chasing") and occasionally release the joystick, grasp the lever, move it forwards and back in order to collect a reward, and then return their hand to the joystick. In both tasks the visual stimuli are accompanied with acoustic signals. To hear these signals during the flight procedure, subjects are equipped with ear-phones, plugged into a laptop.

In one 20 second microgravity episode, task L will be performed five times or task E twice. The investigator starts each task with a click on the keyboard and it stops automatically after 20sec.

Control data will be registered from each subject for the same length of time during level flight at 1g.

During the whole test procedure the subject is not constraint in its natural behaviour except by an easy to open belt which fixes the subject to the chair. The subject can at any time end the experiment.

Equipment used For hand motion measurement and analysis we use a Vicon MX System, consisting of two MX20+ infrared high-speed cameras, each connected via cables with an MX Ultranet which processes the data. The Ultranet is connected with a network cable to a corresponding laptop (Dell).

Force is measured by a 6 degree of freedom force transducer which is part of an ATI DAQ F/T System, consisting of the force sensor Nano 17, a power supply box with booster and a 16-bit A/D converter (DAQ-Card, NI 6036E). It uses the PCMCIA bus of a second laptop (Fujitsu).

The position of the object to move is measured by an inductive position encoder (dc position encoder type 8740-5100 by burster).

The eye movement will be recorded by a standard USB-camera or a commercial eye-tracker (Tobii T60) when available.

All devices are commercially available and are used according their CE marking.

Experimental protocol Before flight subjects will be familiarised with the protocol. Two subjects will be studied during each flight. On ground, each subject gets 6 reflexive markers (6mm diameter) stuck on their right hand (4 on index, 2 on thumb, fixed with double sided adhesive tape).

The first subject takes a seat at the experimental set-up, the second one on an aircraft seat. The tested subject is then equipped with ear-phones plugged into a laptop. It helps to focus the attention on the tasks which are accompanied with acoustic signals. Recording devices are then adjusted to the subject by a standard calibration procedure, done by the test-operator. Before entering the first parabola the subject executes the same two grasping-tasks on level flight. After the first test parabola, during each 0g period it has to execute the grasping movements in one of each task - 4 parabolas task L with five episodes each, 10 parabolas task E with two episodes each. Entering the 0g phase the operator starts the test by a click on the keyboard, afterwards the tasks stop automatically. During 1g and 1,8g phases the test is interrupted. After the 15th parabola the subjects switch places and the second one starts with the tests during the 0g phases. On level flight back to the airport it executes the same two tasks again as control condition.

Tipo de estudio

Intervencionista

Inscripción (Anticipado)

18

Fase

  • No aplica

Contactos y Ubicaciones

Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.

Ubicaciones de estudio

    • Basse-Normandie
      • Caen CEDEX, Basse-Normandie, Francia, 14032
        • Reclutamiento
        • Umr Ucbn/Inserm U1075 Comete

Criterios de participación

Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.

Criterio de elegibilidad

Edades elegibles para estudiar

18 años a 65 años (Adulto, Adulto Mayor)

Acepta Voluntarios Saludables

Sí

Géneros elegibles para el estudio

Todos

Descripción

Inclusion Criteria:

  • healthy volunteers (men or women),
  • aged from 18 to 65,
  • right handed,
  • affiliated to a Social Security system and, for non-French resident, holding an European Health Insurance Card (EHIC)
  • who accept to take part in the study,
  • who have given their written stated consent,
  • who have passed a medical examination similar to a standard aviation medical examination for private pilot aptitude. There will be no additional test performed for subject selection.

Exclusion Criteria:

  • person who took part in a previous biomedical research protocol, of which exclusion period is not terminated,
  • pregnant women.

Plan de estudios

Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.

¿Cómo está diseñado el estudio?

Detalles de diseño

  • Propósito principal: Ciencia básica
  • Asignación: N / A
  • Modelo Intervencionista: Asignación de un solo grupo
  • Enmascaramiento: Ninguno (etiqueta abierta)

Armas e Intervenciones

Grupo de participantes/brazo
Intervención / Tratamiento
Otro: Motor skills measurements
  • the kinematics measurements of the right hand with a motion analysis system;
  • the measurements of forces applied by the hand on the object to be grasped and moved with a 6 degree of freedom force sensor;
  • the measurement of position of the moved object with an inductive position encoder.

¿Qué mide el estudio?

Medidas de resultado primarias

Medida de resultado
Medida Descripción
Periodo de tiempo
Gravity induced change in movement time (ms)
Periodo de tiempo: baseline
Measured by 3D videocamera, it is the time between the beginning of the hand movement and the contact of the hand on the object
baseline
Gravity induced change in peak velocity of the hand (deg/sec)
Periodo de tiempo: baseline
Measured by 3D videocamera
baseline
Gravity induced change in the maximum grip aperture of the hand (mm)
Periodo de tiempo: baseline
Measured by 3D videocamera. It is the maximum distance between the first and the fifth digit before hand grasps the object
baseline
Gravity induced change in the initial force applied by the hand on the grasped object (newton)
Periodo de tiempo: baseline
Force measured by a strain gauge
baseline

Colaboradores e Investigadores

Aquí es donde encontrará personas y organizaciones involucradas en este estudio.

Fechas de registro del estudio

Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados ​​por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.

Fechas importantes del estudio

Inicio del estudio

1 de octubre de 2010

Finalización primaria (Anticipado)

1 de diciembre de 2016

Fechas de registro del estudio

Enviado por primera vez

28 de julio de 2015

Primero enviado que cumplió con los criterios de control de calidad

30 de septiembre de 2015

Publicado por primera vez (Estimar)

2 de octubre de 2015

Actualizaciones de registros de estudio

Última actualización publicada (Estimar)

2 de octubre de 2015

Última actualización enviada que cumplió con los criterios de control de calidad

30 de septiembre de 2015

Última verificación

1 de septiembre de 2015

Más información

Términos relacionados con este estudio

Palabras clave

Otros números de identificación del estudio

  • 10-084

Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .

Suscribir