Sciatic Neural Mobilization in Lumbar-Related Leg Pain
9 de mayo de 2026 actualizado por: Yunus Emre Tutuneken, Istinye University
Immediate Effects of Sciatic Neural Mobilization on Balance and Proprioception in Patients With Low Back Pain and Radiating Leg Pain: A Prospective Randomized Clinical Trial
Low back pain is one of the most prevalent musculoskeletal disorders worldwide and significantly reduces individuals' quality of life, functional capacity, and productivity. Lumbar-related leg pain (LRLP) is observed in a substantial proportion of patients with low back pain and is associated with neurodynamic dysfunctions arising from peripheral nerve sensitization. Although the effects of neural mobilization on pain and functional outcomes have been investigated in the literature, studies examining its short-term effects on balance and proprioception remain limited. Therefore, this study aims to determine the immediate effects of sciatic nerve neural mobilization on balance and proprioception in individuals with LRLP exhibiting peripheral nerve sensitivity.
The study will be designed as a prospective, randomized, controlled clinical trial. Participants will be recruited from individuals presenting to the Istinye University Health Practice and Research Center Hospital who meet the inclusion criteria. Following random allocation, 52 participants will be assigned either to the intervention group (neural mobilization) or the sham group (sham mobilization). In addition to a single-session standard conventional physiotherapy program, each group will receive its respective intervention protocol. Assessments will be conducted at two time points: before treatment and immediately after treatment.
Static and dynamic balance as well as proprioception will be evaluated using the ProKin balance system; muscle mechanical properties will be assessed using the MyotonPRO device; pain threshold will be measured with an algometer; and flexibility will be evaluated using the sit-and-reach test.
Descripción general del estudio
Estado
Aún no reclutando
Condiciones
Intervención / Tratamiento
Tipo de estudio
Intervencionista
Inscripción (Estimado)
52
Fase
- No aplica
Contactos y Ubicaciones
Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.
Estudio Contacto
- Nombre: YUNUS EMRE TÜTÜNEKEN, PhD
- Número de teléfono: +905435912455
- Correo electrónico: emre.tutuneken@gmail.com
Criterios de participación
Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.
Criterio de elegibilidad
Edades elegibles para estudiar
- Adulto
Acepta Voluntarios Saludables
No
Descripción
Inclusion Criteria:
- Having low back pain accompanied by radiating leg pain (radicular or pseudoradicular pain) for at least 3 weeks
- Demonstration of peripheral nerve sensitivity through clinical evaluation and neurodynamic tests
- Pain intensity of at least 3 on the Visual Analog Scale (VAS)
- Ability to understand verbal and written Turkish instructions
- Providing signed informed consent
Exclusion Criteria:
- Presence of surgical indication due to acute disc herniation or advanced lumbar disc pathology
- History of spinal surgery or spinal trauma
- Low back pain associated with other pathologies (e.g., rheumatic diseases, multiple sclerosis, malignancy)
- Instability conditions such as spondylolysis and spondylolisthesis
- Pregnancy
- Obesity (BMI ≥ 30 kg/m²)
- Orthopedic problems or chronic diseases that may limit exercise participation
- Physiotherapy or steroid injection treatment within the last 3 months
Plan de estudios
Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: Tratamiento
- Asignación: Aleatorizado
- Modelo Intervencionista: Asignación paralela
- Enmascaramiento: Triple
Armas e Intervenciones
Grupo de participantes/brazo |
Intervención / Tratamiento |
|---|---|
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Experimental: Real neural mobilization
|
Participants in the intervention group will receive sciatic neural mobilization in addition to a single-session standard conventional physiotherapy program.
The conventional treatment program will consist of hot pack application, transcutaneous electrical nerve stimulation (TENS), and exercises aimed at improving lumbar muscle activation, flexibility, and proprioceptive awareness.
Sciatic neural mobilization will be performed based on controlled neural sliding and tensioning principles along the sciatic nerve, with the aim of enhancing neural mobility, improving neurodynamic mechanisms, and supporting neuromuscular control.
All interventions will be administered by experienced physiotherapists according to standardized protocols.
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|
Comparador falso: Sham neural mobilization
|
Participants in the sham group will receive the same single-session standard conventional physiotherapy program as the intervention group.
In addition, sham sciatic neural mobilization will be applied.
In the sham intervention, procedures similar to those used in the intervention group will be performed at a minimal level without producing therapeutic neural tension or sliding effects.
This approach is intended to distinguish the specific effects of the intervention from placebo effects.
All procedures will be carried out by experienced physiotherapists in accordance with standardized protocols.
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¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
|
Static Balance
Periodo de tiempo: 30 minute
|
Static balance will be assessed using the ProKin Balance Assessment System.
The ProKin system is a computer-assisted evaluation device equipped with an integrated force platform and motion sensors that objectively measure postural stability, weight distribution, and balance control.
During the static balance assessment, participants will stand on a stable platform and will be instructed to maintain a steady posture for 30 seconds under both eyes-open and eyes-closed conditions.
Parameters, including sway area and center of pressure path length will be recorded.
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30 minute
|
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Dynamic Balance
Periodo de tiempo: 30 minute
|
Dynamic balance will also be evaluated using the ProKin Balance Assessment System.
The assessment will be performed on a movable platform, where participants will be instructed to maintain balance by targeting the center point with visual feedback.
During the evaluation, variables such as platform tilt angle, movement duration, and stability index will be recorded.
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30 minute
|
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Proprioception
Periodo de tiempo: 30 minute
|
Proprioception will be assessed using the ProKin Balance Assessment System through the evaluation of lower extremity joint position sense.
Participants will be asked to complete the circular trajectory determined by the device, and proprioceptive performance will be recorded accordingly.
|
30 minute
|
Medidas de resultado secundarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
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Muscle Tone
Periodo de tiempo: 30 minute
|
Lumbar erector spinae muscle tone will be assessed using the MyotonPRO device.
Muscle tone represents the natural oscillation frequency of the muscle at rest and reflects the passive tension state of the muscle tissue.
Higher frequency values indicate increased resting muscle tension and altered neuromuscular regulation.
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30 minute
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Muscle Stiffness
Periodo de tiempo: 30 minute
|
Lumbar erector spinae muscle stiffness will be evaluated using the MyotonPRO device.
Muscle stiffness refers to the resistance of muscle tissue to external mechanical deformation and provides information regarding the biomechanical properties of the muscle.
Increased stiffness values may indicate impaired tissue flexibility and altered viscoelastic behavior.
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30 minute
|
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Pressure pain threshold
Periodo de tiempo: 30 minute
|
Pressure pain threshold will be assessed using a digital algometer applied bilaterally over the lumbar erector spinae muscle at the L3 level.
The device objectively measures the minimum pressure perceived as painful, providing a reliable evaluation of mechanical pain sensitivity and alterations in nociceptive processing in individuals with low back pain.
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30 minute
|
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Flexibility
Periodo de tiempo: 30 minute
|
Lumbar and hamstring flexibility will be evaluated using the Sit and Reach test with a standardized measurement box.
Participants will perform controlled forward trunk flexion while maintaining full knee extension.
The maximum reaching distance achieved will be recorded in centimeters, providing a reliable assessment of posterior chain flexibility and lumbopelvic mobility.
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30 minute
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Global Change Scale (GCS)
Periodo de tiempo: 30 minute
|
The GCS will be used to assess the patient's perceived improvement following treatment and their level of satisfaction in comparison with their pre-treatment condition.
Patients will be asked to rate the perceived effect of the treatment using a 5-point Likert scale as follows: "-2" (much worse), "-1" (worse), "0" (no change), "+1" (better), and "+2" (much better).
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30 minute
|
Colaboradores e Investigadores
Aquí es donde encontrará personas y organizaciones involucradas en este estudio.
Patrocinador
Fechas de registro del estudio
Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.
Fechas importantes del estudio
Inicio del estudio (Estimado)
15 de junio de 2026
Finalización primaria (Estimado)
15 de octubre de 2026
Finalización del estudio (Estimado)
15 de octubre de 2026
Fechas de registro del estudio
Enviado por primera vez
9 de mayo de 2026
Primero enviado que cumplió con los criterios de control de calidad
9 de mayo de 2026
Publicado por primera vez (Actual)
15 de mayo de 2026
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
15 de mayo de 2026
Última actualización enviada que cumplió con los criterios de control de calidad
9 de mayo de 2026
Última verificación
1 de mayo de 2026
Más información
Términos relacionados con este estudio
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
- 20 (Sophies Minde Ortopedi AS)
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
No
Estudia un producto de dispositivo regulado por la FDA de EE. UU.
No
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