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EFFECT OF MULLIGAN CERVICAL SUSTAINED NATURAL APOPHYSEAL GLIDE ON POSTURAL STABILITY IN PATIENTS WITH CHRONIC NECK PAIN (SNAG Mulligan)

23 de junio de 2026 actualizado por: Menna Allah Ahmed Marei Elnaggar

This study seeks to address the identified research gap by objectively investigating the effect of Mulligan Cervical SNAGs on postural stability in individuals with chronic neck pain and mobility impairments. The findings aim to provide evidence-based insights into whether restoring joint mobility through this manual intervention can effectively enhance sensorimotor control and balance performance. The study aims to determine if adding SNAG to a conventional exercise program provides superior improvements in balance indices (OSI, APSI, MLSI), Pain, functional disability, Range of motion, Joint position sense, and kinesiophobia compared to exercise alone. The primary purpose of this study is to answer the following research questions:

  • Does the application of cervical SNAGs lead to a significant improvement in the postural stability of patients with chronic neck pain with mobility deficits?
  • Is there a correlation between the improvement in cervical range of motion (ROM) following SNAGs and the enhancement of postural control performance?

Descripción general del estudio

Descripción detallada

Chronic neck pain associated with mobility deficits is a prevalent musculoskeletal condition that extends beyond localized discomfort to involve significant sensorimotor disturbances. The cervical spine plays a pivotal role in postural control due to its high density of mechanoreceptors and its intricate integration with the vestibular and visual systems. Patients with CNP frequently exhibit impaired proprioception and increased postural sway. This leads to a higher risk of falls and functional limitations. If SNAG is proven effective, the results will help clinicians justify the inclusion of Mulligan SNAGs in rehabilitation protocols not only to restore mobility and reduce pain but also to address balance impairments and kinesiophobia in patients with chronic neck pain. From a patient perspective, these improvements may enhance functional performance, confidence during movement, and quality of life. From a socioeconomic perspective, improving functional abilities and reducing disability may decrease healthcare costs, work absenteeism, and the long-term burden associated with chronic neck pain. Scientifically, this study may contribute to the growing body of evidence regarding the sensorimotor and balance-related effects of Mulligan SNAG techniques and provide further insight into the relationship between cervical mobility, postural stability, and kinesiophobia in patients with chronic neck pain.

Tipo de estudio

Intervencionista

Inscripción (Estimado)

44

Fase

  • No aplica

Contactos y Ubicaciones

Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.

Estudio Contacto

  • Nombre: Menna-Allah A Elnaggar, demonstrator
  • Número de teléfono: +201069014391
  • Correo electrónico: me370433@gmail.com

Copia de seguridad de contactos de estudio

  • Nombre: Rewan M Aloush, Teaching Assistant
  • Número de teléfono: +201024232512
  • Correo electrónico: rewan.aloush@gmail.com

Ubicaciones de estudio

      • Gamasa, Egipto
        • Faculty of Physical Therapy Delta University
        • Investigador principal:
          • Dr. Akram fathy abdulhamid, Assistant Professor
        • Sub-Investigador:
          • Mohamed Behiry, Assistant Professor
        • Sub-Investigador:
          • Mahmoud Nabhan, lecturer

Criterios de participación

Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.

Criterio de elegibilidad

Edades elegibles para estudiar

  • Adulto

Acepta Voluntarios Saludables

No

Descripción

Inclusion Criteria:

  • The patients will be selected according to the following criteria:

    1. Adults aged between 20 and 45 years
    2. Body mass index from 18.5 - 24.99 kg/ m2.
    3. Chronic neck pain lasting ≥3 months
    4. Diagnosis of neck pain with mobility deficits, including restricted cervical ROM, and pain provoked with movement
    5. Presence of cervical hypomobility confirmed by segmental mobility assessment on clinical examination
    6. Pain intensity ≥3/10 on the numerical Pain Rating Scale
    7. Reduced cervical range of motion in at least one direction measured objectively (by digital inclinometer)
    8. Ability to stand independently without assistive devices (required for postural stability assessment)

Exclusion Criteria:

  • The patients will be excluded if they present with:

    1. Specific causes of neck pain, such as fracture, tumor, infection, inflammatory disease, or cervical myelopathy, confirmed by X Ray and physical examination
    2. Cervical radiculopathy or neurological deficits (e.g., dermatomal sensory loss, reflex changes, or muscle weakness)
    3. History of cervical spine surgery or recent trauma (within the last 6 months)
    4. Vestibular disorders or conditions affecting balance (e.g., vertigo unrelated to cervical origin)
    5. Temporomandibular disorders, significant shoulder pathology, and shoulder surgeries that may influence cervical movement or outcomes
    6. Participation in physiotherapy or manual therapy for neck pain within the previous 3 months
    7. Pregnancy or any medical condition contraindicates manual therapy
    8. History of chronic ankle instability
    9. Any lower limb pathology affecting balance

Plan de estudios

Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.

¿Cómo está diseñado el estudio?

Detalles de diseño

  • Propósito principal: Tratamiento
  • Asignación: Aleatorizado
  • Modelo Intervencionista: Asignación paralela
  • Enmascaramiento: Ninguno (etiqueta abierta)

Armas e Intervenciones

Grupo de participantes/brazo
Intervención / Tratamiento
Experimental: Group A will include 22 patients with chronic neck pain with mobility deficits

Group A (Experimental: Mulligan cervical SNAG plus conventional physiotherapy)

(Mulligan Cervical SNAG Plus Conventional Therapy)

Mulligan Cervical SNAG Technique Protocol:

  • Patient positioning: Seated or standing, with spine in neutral or slight flexion.
  • Therapist hand placement: Thumb or fingers on the targeted cervical vertebra (e.g., C2-C7 or upper thoracic T1-T4).
  • Direction of glide: Anterior and upward glide along the plane of the facet joint, synchronized with the patient's active movement (e.g., rotation, extension)
  • Repetitions: 10 repetitions per session, each held for 10 seconds, with rest intervals
  • Session structure: SNAG mobilizations performed first, followed by conventional exercises.
  • Cervical spine: Targeted for joint position sense, pain, and dizziness Conventional Therapy Based on the American Physical Therapy Association (APTA) Clinical Practice Guidelines for Neck Pain with Mobility Deficits, participants in the conventional therapy
The Biodex Balance System SD Model 950-441(Biodex Medical Systems, Inc.) is a multi-dimensional (static and dynamic) postural control assessment and training system. It provides objective, valid, and reliable measures of a patient's ability to balance on stable and unstable surfaces. It measures the overall Stability Index (OSI), anterior/posterior stability index (APSI), and medial/lateral stability index (MLSI). Its intraclass correlation coefficient (ICC) reliability is R = 0.92 (OSI), R = 0.89 (APSI), and R = 0.93 (MLSI). Chronic neck pain subjects have demonstrated significantly worse Biodex balance performance across OSI, APSI, and MLSI

The Numerical Pain Rating Scale (NPRS) is a unidimensional measure of pain intensity that serves as a segmented numerical version of the visual analog scale (VAS). It consists of an 11-point scale where the respondent selects a whole number from 0 to 10 that best reflects the intensity of their pain, with 0 representing "no pain" and 10 representing the "worst imaginable pain" .

The NPRS has demonstrated high construct and criterion validity for assessing pain severity in patients with chronic musculoskeletal disorders. It is considered a valid tool for differentiating pain characteristics between individuals with chronic neck pain and healthy controls. The research suggests that the NPRS is often more responsive to clinical changes and easier for patients to comprehend than the traditional VAS .This scale is characterized by excellent test-retest reliability (ICC: 0.95),

Neck disability index (NDI) is self-reported assessment includes ten items: pain severity, personal care, lifting, work, headaches, concentration, sleeping, driving, reading, and recreation. Higher scores imply a greater level of disability. Arabic version of the NDI was used to assess Arabic patients with neck pain, as the Arabic version of the NDI is reliable and valid
A digital inclinometer is a handheld electronic device used to objectively measure the degrees of spinal curvature by detecting inclination relative to the force of gravity.In cervical spine assessment, it is used to quantify movements including flexion, extension, lateral flexion, and rotation.The digital inclinometer is recognized as a highly valid and reliable instrument for measuring cervical range of motion (CROM). Recent studies have reported excellent intra-rater and inter-rater reliability (ICC > 0.85), particularly for cervical rotation and lateral flexion. It is often preferred over traditional goniometry because it provides precise, objective, and quantitative data that is less susceptible to manual measurement error.
The TSK-11 is a shortened, 11-item version of the original Tampa Scale, designed to assess kinesiophobia. Defined as an irrational and debilitating fear of physical movement resulting from a feeling of vulnerability to painful injury or re-injury . The Arabic version was developed to provide a linguistically and culturally adapted tool for assessing fear-avoidance beliefs in Arabic-speaking populations. The Arabic version of the TSK-11 has been cross- culturally validated and demonstrates strong psychometric properties. It exhibits high internal consistency, with Cronbach's alpha values typically ranging from 0.86 to 0.90, and excellent test-retest reliability. It shows significant concurrent validity, as scores are strongly correlated with pain intensity (NPRS) and functional disability measures like the Neck Disability Index.
An overhead LASER pointer will be used to assess cervical proprioception by performing the Cervical Joint Position Error (JPE) test. The Joint Position Sense Error (JPSE) is considered one of the essential measures to clinically assess cervical proprioception. The test has good (ICC: 0.77-0.78)

Patient positioning: Seated or standing, with spine in neutral or slight flexion.

  • Therapist hand placement: Thumb or fingers on the targeted cervical vertebra (e.g., C2-C7 or upper thoracic T1-T4).
  • Direction of glide: Anterior and upward glide along the plane of the facet joint, synchronized with the patient's active movement (e.g., rotation, extension)
  • Repetitions: 10 repetitions per session, each held for 10 seconds, with rest intervals.
  • Session structure: SNAG mobilizations performed first, followed by conventional exercises.
  • Cervical spine: Targeted for joint position sense, pain, and dizziness.

Technique variations:

• Minor adjustments in force direction to optimize symptom reduction.

Based on the American Physical Therapy Association (APTA) Clinical Practice Guidelines for Neck Pain with Mobility Deficits, participants in the conventional therapy group received a multimodal treatment program consisting of mobility exercises, strengthening and endurance training, stretching exercises, and patient education

  • Cervical and thoracic mobility exercises.
  • Strengthening and endurance exercises for the deep cervical flexors, cervical extensors, and scapulothoracic muscles.
  • Stretching exercises for the upper trapezius, levator scapulae, pectoral, and cervical muscles.
  • Patient education regarding posture, ergonomics, activity modification, and self-management strategies.

Sequencing:

• SNAG mobilizations performed at session start, followed by active exercises and stretching

Manual therapy timing:

• SNAG component adds ~10 minutes to a 20-minute exercise session

Otro: Group B = 22 patients with chronic neck pain with mobility deficits

Control Group (Conventional Therapy Only)

  • Range of motion (ROM) exercises: Cervical flexion, extension, rotation, lateral flexion
  • Strengthening: Deep cervical flexors, scapular stabilizers
  • Stretching: Targeting neck and upper back muscles (Upper trapezius stretch - Levator scapulae stretch - Pectoralis stretch)
  • Patient education: Posture, ergonomics, activity modification.

Protocol structure:

  • Exercises and manual therapy delivered in 20-30 minute sessions
  • No SNAG mobilizations. Treatment Frequency and Session Duration

Typical regimen:

  • 2 sessions/week for eight weeks.
  • 16 sessions total.
  • 4-week follow-up.
  • Session duration: 20-30 minutes.
The Biodex Balance System SD Model 950-441(Biodex Medical Systems, Inc.) is a multi-dimensional (static and dynamic) postural control assessment and training system. It provides objective, valid, and reliable measures of a patient's ability to balance on stable and unstable surfaces. It measures the overall Stability Index (OSI), anterior/posterior stability index (APSI), and medial/lateral stability index (MLSI). Its intraclass correlation coefficient (ICC) reliability is R = 0.92 (OSI), R = 0.89 (APSI), and R = 0.93 (MLSI). Chronic neck pain subjects have demonstrated significantly worse Biodex balance performance across OSI, APSI, and MLSI

The Numerical Pain Rating Scale (NPRS) is a unidimensional measure of pain intensity that serves as a segmented numerical version of the visual analog scale (VAS). It consists of an 11-point scale where the respondent selects a whole number from 0 to 10 that best reflects the intensity of their pain, with 0 representing "no pain" and 10 representing the "worst imaginable pain" .

The NPRS has demonstrated high construct and criterion validity for assessing pain severity in patients with chronic musculoskeletal disorders. It is considered a valid tool for differentiating pain characteristics between individuals with chronic neck pain and healthy controls. The research suggests that the NPRS is often more responsive to clinical changes and easier for patients to comprehend than the traditional VAS .This scale is characterized by excellent test-retest reliability (ICC: 0.95),

Neck disability index (NDI) is self-reported assessment includes ten items: pain severity, personal care, lifting, work, headaches, concentration, sleeping, driving, reading, and recreation. Higher scores imply a greater level of disability. Arabic version of the NDI was used to assess Arabic patients with neck pain, as the Arabic version of the NDI is reliable and valid
A digital inclinometer is a handheld electronic device used to objectively measure the degrees of spinal curvature by detecting inclination relative to the force of gravity.In cervical spine assessment, it is used to quantify movements including flexion, extension, lateral flexion, and rotation.The digital inclinometer is recognized as a highly valid and reliable instrument for measuring cervical range of motion (CROM). Recent studies have reported excellent intra-rater and inter-rater reliability (ICC > 0.85), particularly for cervical rotation and lateral flexion. It is often preferred over traditional goniometry because it provides precise, objective, and quantitative data that is less susceptible to manual measurement error.
The TSK-11 is a shortened, 11-item version of the original Tampa Scale, designed to assess kinesiophobia. Defined as an irrational and debilitating fear of physical movement resulting from a feeling of vulnerability to painful injury or re-injury . The Arabic version was developed to provide a linguistically and culturally adapted tool for assessing fear-avoidance beliefs in Arabic-speaking populations. The Arabic version of the TSK-11 has been cross- culturally validated and demonstrates strong psychometric properties. It exhibits high internal consistency, with Cronbach's alpha values typically ranging from 0.86 to 0.90, and excellent test-retest reliability. It shows significant concurrent validity, as scores are strongly correlated with pain intensity (NPRS) and functional disability measures like the Neck Disability Index.
An overhead LASER pointer will be used to assess cervical proprioception by performing the Cervical Joint Position Error (JPE) test. The Joint Position Sense Error (JPSE) is considered one of the essential measures to clinically assess cervical proprioception. The test has good (ICC: 0.77-0.78)

Based on the American Physical Therapy Association (APTA) Clinical Practice Guidelines for Neck Pain with Mobility Deficits, participants in the conventional therapy group received a multimodal treatment program consisting of mobility exercises, strengthening and endurance training, stretching exercises, and patient education

  • Cervical and thoracic mobility exercises.
  • Strengthening and endurance exercises for the deep cervical flexors, cervical extensors, and scapulothoracic muscles.
  • Stretching exercises for the upper trapezius, levator scapulae, pectoral, and cervical muscles.
  • Patient education regarding posture, ergonomics, activity modification, and self-management strategies.

Sequencing:

• SNAG mobilizations performed at session start, followed by active exercises and stretching

Manual therapy timing:

• SNAG component adds ~10 minutes to a 20-minute exercise session

¿Qué mide el estudio?

Medidas de resultado primarias

Medida de resultado
Medida Descripción
Periodo de tiempo
A) Postural Stability (Biodex Balance System)
Periodo de tiempo: before the intervention, after 8 weeks, and at a 4-week follow- up.

Overall Stability Index (OSI) - total amount of platform deviation.

  • Anterior-Posterior Stability Index (APSI) - sagittal plane sway.
  • Medial-Lateral Stability Index (MLSI) - frontal plane sway. These indices are mathematically defined in research: APSI and MLSI Calculated from the deviation of platform angles along X and Y axes

(Higher scores = worse balance Reliability Evidence

  • ICC OSI = 0.92, APSI = 0.89, MLSI = 0.93
  • Indicates excellent reliability for research.

For chronic cervical pain with hypomobility, the most appropriate

Biodex protocol (supported by evidence) is:

  • Static Postural Stability Test:
  • Platform locked
  • 3 trials × 20 s
  • Eyes open
  • Compute OSI, APSI, MLSI Dynamic Postural Stability Test
  • Platform level 8 (commonly used mid-level)
  • 3 trials × 20 s
  • Eyes open A) Compute OSI, APSI, MLSI
before the intervention, after 8 weeks, and at a 4-week follow- up.

Medidas de resultado secundarias

Medida de resultado
Medida Descripción
Periodo de tiempo
Numerical Pain Rating Scale (NPRS)
Periodo de tiempo: before the intervention, after 8 weeks, and at a 4-week follow- up.

The NPRS is an 11-point self-reported scale (0-10) for pain intensity.

  1. Ask the patient to rate their pain intensity on a scale from 0 = no pain to 10 = worst possible pain.
  2. It can assess current pain, pain in the last 24 hours .
  3. The scale is valid, reliable, and widely used in clinical and research settings. Standard instructions to participants "Please rate your pain intensity on a scale from 0 to 10, where 0 means no pain at all, and 10 means the worst pain imaginable." This standardized wording is supported by multiple trials.
before the intervention, after 8 weeks, and at a 4-week follow- up.
Neck Disability Index (Arabic Version)
Periodo de tiempo: before the intervention, after 8 weeks, and at a 4-week follow- up.

The Arabic NDI is validated and used widely in neck pain research.

  • The patient completes 10 items, each scored 0-5.
  • Total scores range from 0-50 (or converted to %).
  • Disability categories:

    • 0-4: No disability
    • 5-14: Mild
    • 15-24: Moderate
    • 25-34: Severe Procedure
  • Provide the patient with the questionnaire.
  • Explain each item when needed (common in Arabic versions).
  • Sum the scores and classify disability.
before the intervention, after 8 weeks, and at a 4-week follow- up.
Digital Inclinometer for Cervical ROM
Periodo de tiempo: before the intervention, after 8 weeks, and at a 4-week follow- up.

Multiple studies describe standardized inclinometer protocols

Devices show good validity compared with 3D motion capture

  1. Patient is usually seated upright with feet on the floor.
  2. Place the inclinometer on the vertex of the head aligned with T1 or other fixed reference, depending on the device.
  3. Measure flexion, extension, lateral flexion, and rotation.
  4. Perform 3 trials per direction and use the mean.
before the intervention, after 8 weeks, and at a 4-week follow- up.
Tampa Scale of Kinesiophobia (TSK-11, Arabic Version)
Periodo de tiempo: before the intervention, after 8 weeks, and at a 4-week follow- up.

Kinesiophobia was assessed using the Arabic version of the Tampa Scale of Kinesiophobia (TSK-AV-11), which is a valid and reliable tool

for evaluating fear of movement in Arabic-speaking patients. It consists of 11 items scored on a 4-point Likert scale, with higher scores indicating greater fear of movement Brief and validated for chronic pain including neck pain Contains 11 items, each scored 1 (strongly disagree) to 5 (strongly agree). Procedure

  1. Provide the questionnaire.
  2. Ensure the patient answers all 11 items.
  3. Sum all item scores (minimum 11, maximum 55).
  4. Higher scores = higher kinesiophobia
before the intervention, after 8 weeks, and at a 4-week follow- up.
Overhead Laser Pointer for Cervical Proprioception (Joint Position Error Test)
Periodo de tiempo: before the intervention, after 8 weeks, and at a 4-week follow- up.

Setup

  • Attach a laser pointer to the patient's forehead or headband
  • Place a target on the wall at a distance of 90 cm.
  • Align the laser to the center of the target at the neutral head position. Testing procedure

    1. Patient sits upright, eyes closed (no visual feedback allowed)
    2. Patient moves head:

      1. Rotation right
      2. Rotation left
      3. Flexion
      4. Extension
    3. Patient returns to what they believe is the original neutral position.
    4. Record the deviation in degrees from the center of the target.
    5. Repeat 3-5 trials per direction; average the error
before the intervention, after 8 weeks, and at a 4-week follow- up.

Colaboradores e Investigadores

Aquí es donde encontrará personas y organizaciones involucradas en este estudio.

Fechas de registro del estudio

Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados ​​por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.

Fechas importantes del estudio

Inicio del estudio (Estimado)

20 de agosto de 2026

Finalización primaria (Estimado)

20 de octubre de 2026

Finalización del estudio (Estimado)

1 de noviembre de 2026

Fechas de registro del estudio

Enviado por primera vez

23 de junio de 2026

Primero enviado que cumplió con los criterios de control de calidad

23 de junio de 2026

Publicado por primera vez (Actual)

29 de junio de 2026

Actualizaciones de registros de estudio

Última actualización publicada (Actual)

29 de junio de 2026

Última actualización enviada que cumplió con los criterios de control de calidad

23 de junio de 2026

Última verificación

1 de junio de 2026

Más información

Términos relacionados con este estudio

Otros números de identificación del estudio

  • Mulligan on chronic neck pain

Información sobre medicamentos y dispositivos, documentos del estudio

Estudia un producto farmacéutico regulado por la FDA de EE. UU.

No

Estudia un producto de dispositivo regulado por la FDA de EE. UU.

No

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