Effects of Mental Fatigue Duration on Cortical Activity and Jump Performance (MF-CMJ-EEG)
4 de agosto de 2026 actualizado por: Oğuzhan Bozkurt, Inonu University
Duration-Dependent Effects of Mental Fatigue on Cortical Activation Patterns and Lower-Limb Explosive Performance
"This study investigates whether the length of time spent on a mentally demanding task affects brain activity and jumping performance in physically active young men.
Twelve healthy male university students, all regularly engaged in sport, completed four separate testing sessions on different days, each at least 72 hours apart.
In one session (the control condition), participants watched a calm nature documentary.
In the other three sessions, mental fatigue was induced by having participants perform a demanding attention task (the Stroop color-word test) continuously for 10, 15, or 30 minutes.
Before and after each session, brain activity was recorded using electroencephalography (EEG), a painless method that measures electrical activity through sensors placed on the scalp.
Immediately afterward, participants performed a countermovement jump test, a standard measure of explosive leg power used in sports science.
The study examines whether longer periods of mental fatigue produce progressively larger changes in brain activity and jump performance, and whether changes in brain activity are related to changes in jumping ability.
The findings may help athletes, coaches, and students better understand how mentally tiring activities, such as studying or exams, could affect physical performance shortly afterward."
Descripción general del estudio
Estado
Terminado
Descripción detallada
"Mental fatigue is a psychobiological state induced by prolonged demanding cognitive activity, characterized by subjective tiredness and measurable decrements in sustained attention and executive control. While mental fatigue has been linked to impairments in endurance, strength, and anaerobic performance, evidence regarding explosive, single-effort tasks such as the countermovement jump (CMJ) remains sparse and inconsistent, and it remains unclear whether the cortical and behavioral consequences of mental fatigue scale with the duration of the inducing cognitive task.
This study used a single-group, repeated-measures crossover design in which the same twelve participants completed a non-fatiguing control condition and three graded mental-fatigue protocols (10, 15, and 30 minutes of continuous Stroop-task performance), with session order counterbalanced across participants and a minimum 72-hour washout between sessions. All sessions were conducted in the same laboratory within a consistent daily time window (10:00 ± 1 hour) to minimize circadian confounds.
Resting-state EEG (spectral power in delta, theta, alpha, and beta bands; theta/alpha and theta/beta ratios; spectral and sample entropy; frontal theta and posterior alpha) and subjective fatigue (0-10 visual analogue scale) were assessed immediately before and after each condition. Countermovement-jump height and its kinetic/kinematic correlates were then measured to evaluate explosive lower-limb power, the study's primary outcome; EEG parameters were treated as secondary, mechanistic outcomes.
Data were analyzed using repeated-measures ANOVA, Holm-Bonferroni-corrected Friedman/Wilcoxon tests where appropriate, and repeated-measures correlation to examine the relationship between post-intervention EEG parameters and CMJ performance. The study tested the hypothesis that increasing Stroop-task duration would produce progressively larger shifts in EEG-derived cortical activation and parallel reductions in CMJ performance, and that these neurophysiological and performance changes would be significantly associated with one another."
Tipo de estudio
Intervencionista
Inscripción (Actual)
12
Fase
- No aplica
Contactos y Ubicaciones
Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.
Ubicaciones de estudio
-
-
-
Malatya, Turquía (Türkiye), 44280
- İnönü University, Faculty of Sport Sciences
-
-
Criterios de participación
Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.
Criterio de elegibilidad
Edades elegibles para estudiar
- Adulto
Acepta Voluntarios Saludables
Sí
Descripción
Inclusion Criteria:
- Healthy male volunteers aged 18-30 years
- Enrolled in the Faculty of Sport Sciences at İnönü University
- Engaged in structured exercise at least three days per week
- Free of any neurological, psychiatric, cardiovascular, or musculoskeletal disorder
- Normal or corrected-to-normal vision
- Physically capable of completing the experimental protocol safely
Exclusion Criteria:
- Diagnosed neurological, psychiatric, cardiovascular, or musculoskeletal disorder
- Lower-limb injury within the preceding 6 months
- Use of medication known to affect central nervous system function
- Prior diagnosis of a sleep disorder
- Uncorrectable visual impairment or any disturbance of color perception
- Cognitive or sensory limitation likely to interfere with performance of the Stroop task
- Failure to complete a session in full, non-compliance with investigator instructions during testing, inability to produce an EEG recording of analyzable quality for technical reasons, or discontinuation of the experimental procedure for any reason
- Non-compliance with pre-session restrictions (vigorous physical exercise or alcohol consumption within 24 hours before each session; caffeine, energy drinks, or other stimulant substances within 12 hours before each session)
Plan de estudios
Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: Tratamiento
- Asignación: Aleatorizado
- Modelo Intervencionista: Asignación cruzada
- Enmascaramiento: Único
Armas e Intervenciones
Grupo de participantes/brazo |
Intervención / Tratamiento |
|---|---|
|
Comparador falso: Control
Participants viewed a neutral, cognitively undemanding nature documentary for a duration matched to the mental-fatigue protocols, without performing the Stroop task.
|
Viewing of a neutral, cognitively undemanding nature documentary matched in duration to the mental-fatigue protocols, serving as a non-fatiguing control condition.
|
|
Experimental: MF10 (10-min Mental Fatigue)
Participants performed the Stroop color-word task continuously for 10 minutes to induce mental fatigue.
|
Continuous performance of the Stroop color-word interference task for 10 minutes to induce mental fatigue.
|
|
Experimental: MF15 (15-min Mental Fatigue)
Participants performed the Stroop color-word task continuously for 15 minutes to induce mental fatigue.
|
Continuous performance of the Stroop color-word interference task for 15 minutes to induce mental fatigue.
|
|
Experimental: MF30 (30-min Mental Fatigue)
Participants performed the Stroop color-word task continuously for 30 minutes to induce mental fatigue.
|
Continuous performance of the Stroop color-word interference task for 30 minutes to induce mental fatigue.
|
¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
|
Countermovement Jump (CMJ) Height
Periodo de tiempo: Immediately after completion of each experimental protocol (control, and 10-, 15-, and 30-minute Stroop-task mental fatigue conditions); sessions were separated by a minimum 72-hour washout period.
|
Countermovement jump (CMJ) height was assessed using the My Jump Lab application (version 5.2; C. Balsalobre-Fernández, Madrid, Spain) via video recorded at 240 frames/s on an iPad Air 11-inch (M3), positioned on a tripod approximately 2 m from the participant.
Take-off and landing frames were identified manually by the same investigator using the application's frame-by-frame function, and jump height was calculated from flight time using the equation h = (g·t²)/8.
Two jump attempts were performed in each experimental session, with 60 seconds of rest between trials, and the better performance was retained for analysis.
|
Immediately after completion of each experimental protocol (control, and 10-, 15-, and 30-minute Stroop-task mental fatigue conditions); sessions were separated by a minimum 72-hour washout period.
|
Medidas de resultado secundarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
|
Countermovement Jump-Derived Mechanical and Kinematic Parameters
Periodo de tiempo: Immediately after completion of each experimental protocol.
|
Countermovement jump (CMJ)-derived mechanical and kinematic parameters were obtained using the My Jump Lab application from the CMJ assessment performed at the end of each experimental protocol.
Average velocity (m/s), take-off velocity (m/s), and impulse (N·s) were provided automatically by the application as derived sub-parameters, computed from jump height and body mass using the biomechanical model incorporated in My Jump Lab.
Flight time (ms) was calculated from the same video recording using the application's frame-by-frame analysis.
These parameters were analyzed as complementary derived measures of CMJ performance.
|
Immediately after completion of each experimental protocol.
|
|
EEG Absolute Band Power (Delta, Theta, Alpha, Beta)
Periodo de tiempo: Recorded immediately before and immediately after each experimental protocol (control, and 10-, 15-, and 30-minute Stroop-task mental fatigue conditions); each recording lasted 3 minutes with eyes closed.
|
Resting-state EEG was recorded using a 10-electrode montage (Fp1, Fp2, Fz, FC1, FC2, Cz, Pz, O1, Oz, O2) following the international 10-20 system, via a wireless EEG system (Emotiv EPOC Flex) sampling at 256 Hz.
Following preprocessing (0.5-45 Hz band-pass filtering, ICA-based artifact removal, and amplitude normalization), power spectral density was computed for each channel using Welch's method, and absolute power was calculated within the delta (1-4 Hz), theta (4-8 Hz), alpha (8-13 Hz), and beta (13-30 Hz) frequency bands, expressed in normalized (dimensionless) units.
|
Recorded immediately before and immediately after each experimental protocol (control, and 10-, 15-, and 30-minute Stroop-task mental fatigue conditions); each recording lasted 3 minutes with eyes closed.
|
|
EEG Theta/Beta Ratio
Periodo de tiempo: Immediately before and immediately after each experimental protocol.
|
The theta-to-beta power ratio was calculated from resting-state EEG recordings (10-electrode montage, international 10-20 system) by dividing theta-band power by beta-band power for each channel.
The outcome was expressed as a unitless ratio.
|
Immediately before and immediately after each experimental protocol.
|
|
EEG Spectral Entropy
Periodo de tiempo: Immediately before and immediately after each experimental protocol.
|
Spectral entropy was computed from the resting-state EEG power spectrum of each channel as a measure of signal complexity, used to characterize the transition from an alert to a fatigued cortical state.
|
Immediately before and immediately after each experimental protocol.
|
|
EEG Sample Entropy
Periodo de tiempo: Immediately before and immediately after each experimental protocol.
|
Sample entropy was computed from the resting-state EEG time series of each channel as a nonlinear measure of signal irregularity and complexity.
|
Immediately before and immediately after each experimental protocol.
|
|
Frontal Theta Power
Periodo de tiempo: Immediately before and immediately after each experimental protocol.
|
Frontal theta power was extracted from frontal electrode sites (Fp1, Fp2, Fz) as a regional marker of cognitive-control demand and effortful attentional monitoring.
|
Immediately before and immediately after each experimental protocol.
|
|
Posterior Alpha Power
Periodo de tiempo: Immediately before and immediately after each experimental protocol.
|
Posterior alpha power was extracted from occipital electrode sites (O1, Oz, O2) as a regional marker of cortical inhibition and fatigue-related attentional state.
|
Immediately before and immediately after each experimental protocol.
|
|
Subjective Mental Fatigue (VAS Score)
Periodo de tiempo: Immediately before and immediately after each experimental protocol.
|
Subjective mental fatigue was rated using a paper-based 0-10 visual analogue scale, anchored at 0 ("not mentally fatigued at all") and 10 ("the highest possible level of mental fatigue"), in response to the question "How mentally fatigued do you feel right now?" Prior ratings were not visible when a new rating was provided.
|
Immediately before and immediately after each experimental protocol.
|
Colaboradores e Investigadores
Aquí es donde encontrará personas y organizaciones involucradas en este estudio.
Patrocinador
Fechas de registro del estudio
Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.
Fechas importantes del estudio
Inicio del estudio (Actual)
1 de mayo de 2026
Finalización primaria (Actual)
1 de julio de 2026
Finalización del estudio (Actual)
1 de agosto de 2026
Fechas de registro del estudio
Enviado por primera vez
4 de agosto de 2026
Primero enviado que cumplió con los criterios de control de calidad
4 de agosto de 2026
Publicado por primera vez (Actual)
10 de agosto de 2026
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
10 de agosto de 2026
Última actualización enviada que cumplió con los criterios de control de calidad
4 de agosto de 2026
Última verificación
1 de agosto de 2026
Más información
Términos relacionados con este estudio
Palabras clave
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
- INU-2025-8104-MFCMJ
- 2025/8104 (Otro identificador: İnönü University Non-Interventional Clinical Research Ethics Committee)
Plan de datos de participantes individuales (IPD)
¿Planea compartir datos de participantes individuales (IPD)?
NO
Descripción del plan IPD
Individual participant data will not be shared because the study includes a small sample size, and no data-sharing plan was included in the approved study protocol or informed consent.
Aggregate study results will be reported in scientific publications.
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
No
Estudia un producto de dispositivo regulado por la FDA de EE. UU.
No
Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .