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Testare un modello di consegna digitale migliorato per test genetici ereditari di cancro nei giovani adulti con cancro

2 novembre 2026 aggiornato da: Alliance for Clinical Trials in Oncology

Studio di accesso AYA: un modello di consegna abilitato per l'eHealth e Chat-Bot

This phase III trial compares the use of a digital chatbot enabled intervention to standard remote genetic services for increasing uptake of genetic counseling and testing among adolescents and young adult (AYA) cancer patients. Genetic testing for cancer predisposition syndromes has become standard evidence-based practice and can inform enhanced screening and risk reducing measures to reduce cancer morbidity and mortality. Despite this, many AYAs are not receiving recommended genetic counseling and testing. Offering remote telehealth services can address access barriers and chatbots and texting interventions could enhance patient outcomes and reduce provider and staff time. The use of a digital chatbot enabled intervention may be equally as effective as standard remote genetic services in AYA cancer patients undergoing genetic testing.

Panoramica dello studio

Stato

Reclutamento

Condizioni

Intervento / Trattamento

Descrizione dettagliata

The primary and secondary objectives of the study:

PRIMARY OBJECTIVES:

I. To evaluate the efficacy of an enhanced eHealth and chatbot enabled delivery model to increase uptake of genetic counseling.

II. To evaluate the efficacy of an enhanced eHealth and chatbot enabled delivery model to increase uptake of genetic testing.

SECONDARY OBJECTIVE:

I. To evaluate the efficacy of an enhanced eHealth and chatbot enabled delivery model to provide non-inferior short-term and longitudinal cognitive (e.g. knowledge), affective (e.g. distress), and behavioral outcomes (e.g. cancer screening and communication to relatives) and costs.

EXPLORATORY OBJECTIVES:

I. To test for moderators of uptake of counseling and testing (primary objectives).

II. To test for moderators of short-term and longitudinal patient outcomes (secondary objectives).

III. To identify facilitators and barriers to implementation of the enhanced eHealth and chatbot enabled delivery model and standard remote services.

OUTLINE: Patients are randomized to 1 of 2 arms. Non-patient participants are assigned to arm 3.

ARM I: Patients attend a standard of care telehealth visit with a genetic counselor for pretest genetic education. Patients then undergo standard of care genetic testing and attend a telehealth visit with a genetic counselor for disclosure of results.

ARM II: Patients receive access to the Genetic Journey Chatbot and choose to complete digital pre-test genetic education via the digital tool or via telehealth visit with a genetic counselor. Via the chatbot, patients may request a telehealth visit with a genetic counselor at any time to answer unresolved questions. Patients then undergo standard of care genetic testing and attend a telehealth visit with a genetic counselor for disclosure of results. The chatbot remains available to answer questions, assess barriers, and provide reminders for next steps during the testing period.

ARM III: Non-patient participants complete an interview on study.

After completion of study intervention, patients are followed up at 6 and 12 months.

Tipo di studio

Interventistico

Iscrizione (Stimato)

535

Fase

  • Non applicabile

Contatti e Sedi

Questa sezione fornisce i recapiti di coloro che conducono lo studio e informazioni su dove viene condotto lo studio.

Contatto studio

Luoghi di studio

  • Stati Uniti
    • Alaska
      • Anchorage, Alaska, Stati Uniti, 99508
      • Anchorage, Alaska, Stati Uniti, 99508
      • Anchorage, Alaska, Stati Uniti, 99508
      • Anchorage, Alaska, Stati Uniti, 98508
      • Anchorage, Alaska, Stati Uniti, 99508
      • Anchorage, Alaska, Stati Uniti, 99508
      • Fairbanks, Alaska, Stati Uniti, 99701
        • Reclutamento
        • Fairbanks Memorial Hospital
        • Contatto:
        • Investigatore principale:
          • John M. Schallenkamp
    • Arizona
      • Phoenix, Arizona, Stati Uniti, 85004
    • Arkansas
      • Fort Smith, Arkansas, Stati Uniti, 72903
        • Reclutamento
        • Mercy Hospital Fort Smith
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 800-378-9373
        • Investigatore principale:
          • Jay W. Carlson
      • Little Rock, Arkansas, Stati Uniti, 72205
        • Reclutamento
        • CARTI Cancer Center
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
    • California
      • Arroyo Grande, California, Stati Uniti, 93420
        • Reclutamento
        • Mission Hope Medical Oncology - Arroyo Grande
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
      • Burbank, California, Stati Uniti, 91505
        • Reclutamento
        • Providence Saint Joseph Medical Center/Disney Family Cancer Center
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Carmichael, California, Stati Uniti, 95608
      • Carmichael, California, Stati Uniti, 95608
      • Elk Grove, California, Stati Uniti, 95758
      • Merced, California, Stati Uniti, 95340
      • Napa, California, Stati Uniti, 94558
        • Reclutamento
        • Providence Queen of The Valley
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 707-521-3830
      • Rocklin, California, Stati Uniti, 95765
      • Sacramento, California, Stati Uniti, 95816
      • San Luis Obispo, California, Stati Uniti, 93401
        • Reclutamento
        • Pacific Central Coast Health Center-San Luis Obispo
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
      • Santa Cruz, California, Stati Uniti, 95065
        • Reclutamento
        • Dominican Santa Cruz Hospital
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 831-462-7770
        • Investigatore principale:
          • Loretta J. Nastoupil
      • Santa Maria, California, Stati Uniti, 93444
        • Reclutamento
        • Mission Hope Medical Oncology - Santa Maria
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
      • Santa Rosa, California, Stati Uniti, 95403
        • Reclutamento
        • Providence Medical Foundation - Santa Rosa
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 707-521-3830
      • Santa Rosa, California, Stati Uniti, 95405
        • Reclutamento
        • Providence Santa Rosa Memorial Hospital
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 707-521-3830
      • Stockton, California, Stati Uniti, 95204
        • Reclutamento
        • Saint Joseph's Medical Center
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 209-461-5257
        • Investigatore principale:
          • Loretta J. Nastoupil
      • Stockton, California, Stati Uniti, 95204
        • Reclutamento
        • Stockton Hematology Oncology Medical Group
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 209-466-2626
      • Woodland, California, Stati Uniti, 95695
    • Colorado
      • Colorado Springs, Colorado, Stati Uniti, 80907
      • Colorado Springs, Colorado, Stati Uniti, 80907
      • Colorado Springs, Colorado, Stati Uniti, 80923
      • Durango, Colorado, Stati Uniti, 81301
      • Durango, Colorado, Stati Uniti, 81301
      • Lakewood, Colorado, Stati Uniti, 80228
        • Reclutamento
        • CommonSpirit Saint Anthony Hospital Cancer Center
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
      • Longmont, Colorado, Stati Uniti, 80501
      • Pueblo, Colorado, Stati Uniti, 81004
      • Westminster, Colorado, Stati Uniti, 80023
    • Delaware
      • Wilmington, Delaware, Stati Uniti, 19803
        • Reclutamento
        • Alfred I duPont Hospital for Children
        • Contatto:
        • Investigatore principale:
          • Emi H. Caywood
    • Florida
      • Fort Lauderdale, Florida, Stati Uniti, 33308
        • Reclutamento
        • Holy Cross Hospital
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • Orlando, Florida, Stati Uniti, 32806
        • Reclutamento
        • Arnold Palmer Hospital for Children
        • Contatto:
        • Investigatore principale:
          • Michelle Amit
      • Orlando, Florida, Stati Uniti, 32827
        • Reclutamento
        • Nemours Children's Hospital
        • Contatto:
        • Investigatore principale:
          • Emi H. Caywood
      • Pensacola, Florida, Stati Uniti, 32504
        • Reclutamento
        • Nemours Children's Clinic - Pensacola
        • Contatto:
        • Investigatore principale:
          • Jeffrey H. Schwartz
    • Georgia
      • Augusta, Georgia, Stati Uniti, 30912
        • Reclutamento
        • Augusta University Medical Center
        • Contatto:
        • Investigatore principale:
          • Anand P. Jillella
    • Hawaii
      • Honolulu, Hawaii, Stati Uniti, 96826
        • Reclutamento
        • Kapiolani Medical Center for Women and Children
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 808-983-6090
        • Investigatore principale:
          • Wade T. Kyono
    • Idaho
      • Boise, Idaho, Stati Uniti, 83712
        • Reclutamento
        • Saint Luke's Cancer Institute - Boise
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Boise, Idaho, Stati Uniti, 83706
        • Reclutamento
        • Saint Alphonsus Cancer Care Center-Boise
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Caldwell, Idaho, Stati Uniti, 83605
        • Reclutamento
        • Saint Alphonsus Cancer Care Center-Caldwell
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Coeur d'Alene, Idaho, Stati Uniti, 83814
        • Reclutamento
        • Kootenai Health - Coeur d'Alene
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
      • Fruitland, Idaho, Stati Uniti, 83619
        • Reclutamento
        • Saint Luke's Cancer Institute - Fruitland
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Meridian, Idaho, Stati Uniti, 83642
        • Reclutamento
        • Idaho Urologic Institute-Meridian
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Meridian, Idaho, Stati Uniti, 83642
        • Reclutamento
        • Saint Luke's Cancer Institute - Meridian
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Nampa, Idaho, Stati Uniti, 83687
        • Reclutamento
        • Saint Luke's Cancer Institute - Nampa
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Nampa, Idaho, Stati Uniti, 83687
        • Reclutamento
        • Saint Alphonsus Cancer Care Center-Nampa
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Post Falls, Idaho, Stati Uniti, 83854
        • Reclutamento
        • Kootenai Clinic Cancer Services - Post Falls
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
      • Sandpoint, Idaho, Stati Uniti, 83864
        • Reclutamento
        • Kootenai Clinic Cancer Services - Sandpoint
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
      • Twin Falls, Idaho, Stati Uniti, 83301
        • Reclutamento
        • Saint Luke's Cancer Institute - Twin Falls
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
    • Illinois
      • Alton, Illinois, Stati Uniti, 62002
        • Reclutamento
        • OSF Saint Anthony's Health Center
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 618-463-5623
      • Aurora, Illinois, Stati Uniti, 60506
        • Reclutamento
        • Advocate Outpatient Center - Aurora
        • Investigatore principale:
          • Sigrun Hallmeyer
        • Contatto:
      • Barrington, Illinois, Stati Uniti, 60010
        • Reclutamento
        • Advocate Good Shepherd Hospital
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 847-842-4847
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Bloomington, Illinois, Stati Uniti, 61704
        • Reclutamento
        • Illinois CancerCare-Bloomington
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Canton, Illinois, Stati Uniti, 61520
        • Reclutamento
        • Illinois CancerCare-Canton
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Carbondale, Illinois, Stati Uniti, 62902
        • Reclutamento
        • Memorial Hospital of Carbondale
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
      • Carterville, Illinois, Stati Uniti, 62918
        • Reclutamento
        • SIH Cancer Institute
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
      • Carthage, Illinois, Stati Uniti, 62321
        • Reclutamento
        • Illinois CancerCare-Carthage
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Centralia, Illinois, Stati Uniti, 62801
        • Reclutamento
        • Centralia Oncology Clinic
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
      • Centralia, Illinois, Stati Uniti, 62801
        • Sospeso
        • Saint Mary's Hospital
      • Chicago, Illinois, Stati Uniti, 60657
        • Reclutamento
        • Advocate Illinois Masonic Medical Center
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 773-296-5360
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Crystal Lake, Illinois, Stati Uniti, 60014
        • Reclutamento
        • AMG Crystal Lake - Oncology
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Danville, Illinois, Stati Uniti, 61832
        • Reclutamento
        • Carle at The Riverfront
        • Investigatore principale:
          • Kendrith M. Rowland
        • Contatto:
      • Decatur, Illinois, Stati Uniti, 62526
        • Reclutamento
        • Cancer Care Specialists of Illinois - Decatur
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
      • Decatur, Illinois, Stati Uniti, 62526
        • Reclutamento
        • Decatur Memorial Hospital
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
      • Dixon, Illinois, Stati Uniti, 61021
        • Reclutamento
        • Illinois CancerCare-Dixon
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 815-285-7800
      • Downers Grove, Illinois, Stati Uniti, 60515
        • Reclutamento
        • Advocate Good Samaritan Hospital
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Effingham, Illinois, Stati Uniti, 62401
        • Reclutamento
        • Carle Physician Group-Effingham
        • Contatto:
        • Investigatore principale:
          • Kendrith M. Rowland
      • Effingham, Illinois, Stati Uniti, 62401
        • Reclutamento
        • Crossroads Cancer Center
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
      • Elgin, Illinois, Stati Uniti, 60123
        • Reclutamento
        • Advocate Sherman Hospital
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 847-429-2907
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Eureka, Illinois, Stati Uniti, 61530
        • Reclutamento
        • Illinois CancerCare-Eureka
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Galesburg, Illinois, Stati Uniti, 61401
        • Reclutamento
        • Illinois CancerCare-Galesburg
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Hazel Crest, Illinois, Stati Uniti, 60429
        • Reclutamento
        • Advocate South Suburban Hospital
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 708-799-9995
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Kewanee, Illinois, Stati Uniti, 61443
        • Reclutamento
        • Illinois CancerCare-Kewanee Clinic
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Libertyville, Illinois, Stati Uniti, 60048
        • Reclutamento
        • AMG Libertyville - Oncology
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Libertyville, Illinois, Stati Uniti, 60048
        • Reclutamento
        • Condell Memorial Hospital
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Macomb, Illinois, Stati Uniti, 61455
        • Reclutamento
        • Illinois CancerCare-Macomb
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Mattoon, Illinois, Stati Uniti, 61938
        • Reclutamento
        • Carle Physician Group-Mattoon/Charleston
        • Contatto:
        • Investigatore principale:
          • Kendrith M. Rowland
      • Mount Vernon, Illinois, Stati Uniti, 62864
        • Reclutamento
        • SSM Health Good Samaritan
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
      • Normal, Illinois, Stati Uniti, 61761
        • Reclutamento
        • Carle BroMenn Medical Center
        • Investigatore principale:
          • Kendrith M. Rowland
        • Contatto:
      • Normal, Illinois, Stati Uniti, 61761
        • Reclutamento
        • Carle Cancer Institute Normal
        • Investigatore principale:
          • Kendrith M. Rowland
        • Contatto:
      • O'Fallon, Illinois, Stati Uniti, 62269
        • Reclutamento
        • Cancer Care Center of O'Fallon
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
      • O'Fallon, Illinois, Stati Uniti, 62269
        • Reclutamento
        • HSHS Saint Elizabeth's Hospital
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
      • Oak Lawn, Illinois, Stati Uniti, 60453-2699
        • Reclutamento
        • Advocate Christ Medical Center
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 800-323-8622
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Oak Lawn, Illinois, Stati Uniti, 60453
        • Reclutamento
        • Advocate Outpatient Center - Oak Lawn
        • Investigatore principale:
          • Sigrun Hallmeyer
        • Contatto:
      • Ottawa, Illinois, Stati Uniti, 61350
        • Reclutamento
        • Illinois CancerCare-Ottawa Clinic
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Palos Heights, Illinois, Stati Uniti, 60463
        • Reclutamento
        • Advocate High Tech Medical Park
        • Investigatore principale:
          • Sigrun Hallmeyer
        • Contatto:
      • Park Ridge, Illinois, Stati Uniti, 60068
        • Reclutamento
        • Advocate Lutheran General Hospital
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 847-384-3621
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Pekin, Illinois, Stati Uniti, 61554
        • Reclutamento
        • Illinois CancerCare-Pekin
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Peoria, Illinois, Stati Uniti, 61615
        • Reclutamento
        • Illinois CancerCare-Peoria
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Peoria, Illinois, Stati Uniti, 61636
        • Reclutamento
        • Methodist Medical Center of Illinois
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Peru, Illinois, Stati Uniti, 61354
        • Reclutamento
        • Illinois CancerCare-Peru
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Peru, Illinois, Stati Uniti, 61354
        • Reclutamento
        • Valley Radiation Oncology
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 815-664-4141
      • Princeton, Illinois, Stati Uniti, 61356
        • Reclutamento
        • Illinois CancerCare-Princeton
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
      • Springfield, Illinois, Stati Uniti, 62702
        • Reclutamento
        • Southern Illinois University School of Medicine
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 217-545-7929
      • Springfield, Illinois, Stati Uniti, 62702
        • Reclutamento
        • Springfield Clinic
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 800-444-7541
      • Springfield, Illinois, Stati Uniti, 62781
        • Reclutamento
        • Springfield Memorial Hospital
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
      • Urbana, Illinois, Stati Uniti, 61801
        • Reclutamento
        • Carle Cancer Center
        • Contatto:
        • Investigatore principale:
          • Kendrith M. Rowland
      • Washington, Illinois, Stati Uniti, 61571
        • Reclutamento
        • Illinois CancerCare - Washington
        • Contatto:
        • Investigatore principale:
          • Bryan A. Faller
    • Iowa
      • Ankeny, Iowa, Stati Uniti, 50023
        • Reclutamento
        • UI Health Care Mission Cancer and Blood - Ankeny Clinic
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 515-241-3305
        • Investigatore principale:
          • Seema Harichand-Herdt
      • Carroll, Iowa, Stati Uniti, 51401
        • Reclutamento
        • Saint Anthony Regional Hospital
        • Contatto:
        • Investigatore principale:
          • Seema Harichand-Herdt
      • Clive, Iowa, Stati Uniti, 50325
        • Reclutamento
        • Mercy Cancer Center-West Lakes
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 515-241-3305
        • Investigatore principale:
          • Richard L. Deming
      • Clive, Iowa, Stati Uniti, 50325
        • Reclutamento
        • UI Health Care Mission Cancer and Blood - West Des Moines Clinic
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 515-241-3305
        • Investigatore principale:
          • Seema Harichand-Herdt
      • Creston, Iowa, Stati Uniti, 50801
        • Sospeso
        • Greater Regional Medical Center
      • Des Moines, Iowa, Stati Uniti, 50314
        • Reclutamento
        • Broadlawns Medical Center
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 515-282-2200
        • Investigatore principale:
          • Seema Harichand-Herdt
      • Des Moines, Iowa, Stati Uniti, 50314
        • Reclutamento
        • Mercy Medical Center - Des Moines
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 515-241-3305
        • Investigatore principale:
          • Richard L. Deming
      • Des Moines, Iowa, Stati Uniti, 50309
        • Reclutamento
        • Iowa Methodist Medical Center
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 515-241-6727
        • Investigatore principale:
          • Seema Harichand-Herdt
      • Des Moines, Iowa, Stati Uniti, 50309
        • Reclutamento
        • UI Health Care Mission Cancer and Blood - Des Moines Clinic
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 515-241-3305
        • Investigatore principale:
          • Seema Harichand-Herdt
      • Des Moines, Iowa, Stati Uniti, 50314
        • Reclutamento
        • UI Health Care Mission Cancer and Blood - Laurel Clinic
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 515-241-3305
        • Investigatore principale:
          • Seema Harichand-Herdt
      • Fort Dodge, Iowa, Stati Uniti, 50501
        • Reclutamento
        • UI Healthcare Mission Cancer and Blood - Fort Dodge
        • Investigatore principale:
          • Seema Harichand-Herdt
        • Contatto:
      • Pella, Iowa, Stati Uniti, 50219
        • Reclutamento
        • UI Healthcare Mission Cancer and Blood - Pella
        • Investigatore principale:
          • Seema Harichand-Herdt
        • Contatto:
      • Waukee, Iowa, Stati Uniti, 50263
        • Reclutamento
        • UI Health Care Mission Cancer and Blood - Waukee Clinic
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 515-241-3305
        • Investigatore principale:
          • Seema Harichand-Herdt
      • West Des Moines, Iowa, Stati Uniti, 50266
        • Reclutamento
        • Mercy Medical Center-West Lakes
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 515-241-3305
        • Investigatore principale:
          • Richard L. Deming
      • West Des Moines, Iowa, Stati Uniti, 50266
        • Reclutamento
        • The Iowa Clinic PC
        • Investigatore principale:
          • Seema Harichand-Herdt
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 515-875-9815
    • Kansas
      • Garden City, Kansas, Stati Uniti, 67846
        • Reclutamento
        • Central Care Cancer Center - Garden City
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
      • Great Bend, Kansas, Stati Uniti, 67530
        • Reclutamento
        • Central Care Cancer Center - Great Bend
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
      • Pittsburg, Kansas, Stati Uniti, 66762
        • Reclutamento
        • Mercy Hospital Pittsburg
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 888-446-3729
    • Kentucky
      • Bardstown, Kentucky, Stati Uniti, 40004
        • Reclutamento
        • CommonSpirit Saint Joseph Hospital - Bardstown
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
      • Corbin, Kentucky, Stati Uniti, 40701
      • Lexington, Kentucky, Stati Uniti, 40504
        • Reclutamento
        • Saint Joseph Radiation Oncology Resource Center
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
      • Lexington, Kentucky, Stati Uniti, 40504
        • Reclutamento
        • CommonSpirit Saint Joseph Hospital - Lexington
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
      • Lexington, Kentucky, Stati Uniti, 40509
        • Reclutamento
        • CommonSpirit Saint Joseph Medical Center - East Lexington
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
      • London, Kentucky, Stati Uniti, 40741
        • Reclutamento
        • CommonSpirit Saint Joseph Hospital London
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
      • Mount Sterling, Kentucky, Stati Uniti, 40353
        • Reclutamento
        • CommonSpirit Saint Joseph Hospital Mount Sterling
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
    • Maine
      • Augusta, Maine, Stati Uniti, 04330
        • Reclutamento
        • Harold Alfond Center for Cancer Care
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 207-626-4855
        • Investigatore principale:
          • Kaylee Underkofler
      • Belfast, Maine, Stati Uniti, 04915
        • Reclutamento
        • MaineHealth Waldo Hospital
        • Contatto:
        • Investigatore principale:
          • Kaylee Underkofler
      • Brunswick, Maine, Stati Uniti, 04011
        • Reclutamento
        • MaineHealth Cancer Care and IV Therapy - Brunswick
        • Contatto:
        • Investigatore principale:
          • Kaylee Underkofler
      • Damariscotta, Maine, Stati Uniti, 04543
        • Reclutamento
        • MaineHealth LincolnHealth Hospital
        • Contatto:
        • Investigatore principale:
          • Kaylee Underkofler
      • Norway, Maine, Stati Uniti, 04268
        • Reclutamento
        • MaineHealth Stephens Hospital
        • Contatto:
        • Investigatore principale:
          • Kaylee Underkofler
      • Rockport, Maine, Stati Uniti, 04856
        • Reclutamento
        • Penobscot Bay Medical Center
        • Contatto:
        • Investigatore principale:
          • Kaylee Underkofler
      • Sanford, Maine, Stati Uniti, 04073
        • Reclutamento
        • MaineHealth Cancer Care and IV Therapy - Sanford
        • Contatto:
        • Investigatore principale:
          • Kaylee Underkofler
      • Scarborough, Maine, Stati Uniti, 04074
        • Reclutamento
        • Maine Children's Cancer Program
        • Contatto:
        • Investigatore principale:
          • Kaylee Underkofler
      • Scarborough, Maine, Stati Uniti, 04074
        • Reclutamento
        • MaineHealth Maine Medical Center- Scarborough
        • Contatto:
        • Investigatore principale:
          • Kaylee Underkofler
      • South Portland, Maine, Stati Uniti, 04106
        • Reclutamento
        • MaineHealth Cancer Care and IV Therapy - South Portland
        • Contatto:
        • Investigatore principale:
          • Kaylee Underkofler
    • Michigan
      • Alma, Michigan, Stati Uniti, 48801
        • Reclutamento
        • MyMichigan Medical Center Gratiot
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Alpena, Michigan, Stati Uniti, 49707
        • Reclutamento
        • MyMichigan Medical Center Alpena
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Ann Arbor, Michigan, Stati Uniti, 48106
        • Reclutamento
        • Trinity Health Saint Joseph Mercy Hospital Ann Arbor
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Ann Arbor, Michigan, Stati Uniti, 48103
      • Brighton, Michigan, Stati Uniti, 48114
        • Reclutamento
        • Trinity Health IHA Medical Group Hematology Oncology - Brighton
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Brighton, Michigan, Stati Uniti, 48114
        • Reclutamento
        • Trinity Health Medical Center - Brighton
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Canton, Michigan, Stati Uniti, 48188
        • Reclutamento
        • Trinity Health IHA Medical Group Hematology Oncology - Canton
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Canton, Michigan, Stati Uniti, 48188
        • Reclutamento
        • Trinity Health Medical Center - Canton
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Chelsea, Michigan, Stati Uniti, 48118
        • Reclutamento
        • Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Chelsea, Michigan, Stati Uniti, 48118
      • Clarkston, Michigan, Stati Uniti, 48346
        • Reclutamento
        • Hematology Oncology Consultants-Clarkston
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Clarkston, Michigan, Stati Uniti, 48346
        • Reclutamento
        • Trinity Health IHA Medical Group - Primary Care - Clarkston
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • Detroit, Michigan, Stati Uniti, 48236
        • Reclutamento
        • Henry Ford Health Saint John Hospital
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • East China Township, Michigan, Stati Uniti, 48054
        • Reclutamento
        • Henry Ford River District Hospital
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • Escanaba, Michigan, Stati Uniti, 49829
        • Reclutamento
        • OSF Saint Francis Hospital and Medical Group
        • Investigatore principale:
          • Anthony J. Jaslowski
        • Contatto:
      • Flint, Michigan, Stati Uniti, 48503
        • Reclutamento
        • Genesee Hematology Oncology PC
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Flint, Michigan, Stati Uniti, 48503
        • Reclutamento
        • Genesys Hurley Cancer Institute
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Flint, Michigan, Stati Uniti, 48503
        • Reclutamento
        • Hurley Medical Center
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Flint, Michigan, Stati Uniti, 48503
        • Reclutamento
        • Cancer Hematology Centers - Flint
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Gladwin, Michigan, Stati Uniti, 48624
        • Reclutamento
        • MyMichigan Medical Center Gladwin
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Grand Rapids, Michigan, Stati Uniti, 49503
        • Reclutamento
        • Trinity Health Grand Rapids Hospital
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Grosse Pointe Woods, Michigan, Stati Uniti, 48236
        • Reclutamento
        • Henry Ford Saint John Hospital - Breast
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Grosse Pointe Woods, Michigan, Stati Uniti, 48236
        • Reclutamento
        • Henry Ford Saint John Hospital - Academic
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • Grosse Pointe Woods, Michigan, Stati Uniti, 48236
        • Reclutamento
        • Henry Ford Saint John Hospital - Van Elslander
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • Lansing, Michigan, Stati Uniti, 48912
        • Reclutamento
        • University of Michigan Health - Sparrow Lansing
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • Livonia, Michigan, Stati Uniti, 48154
        • Reclutamento
        • Trinity Health Saint Mary Mercy Livonia Hospital
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Macomb, Michigan, Stati Uniti, 48044
        • Reclutamento
        • Henry Ford Warren Hospital - Breast Macomb
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • Macomb, Michigan, Stati Uniti, 48044
        • Reclutamento
        • Henry Ford Saint John Hospital - Macomb Medical
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • Midland, Michigan, Stati Uniti, 48670
        • Reclutamento
        • MyMichigan Medical Center Midland
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Mount Pleasant, Michigan, Stati Uniti, 48858
        • Reclutamento
        • MyMichigan Medical Center Mount Pleasant
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Muskegon, Michigan, Stati Uniti, 49444
        • Reclutamento
        • Trinity Health Muskegon Hospital
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Norton Shores, Michigan, Stati Uniti, 49444
        • Reclutamento
        • Cancer and Hematology Centers of Western Michigan - Norton Shores
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Pontiac, Michigan, Stati Uniti, 48341
        • Sospeso
        • Hope Cancer Center
      • Pontiac, Michigan, Stati Uniti, 48341
        • Reclutamento
        • Trinity Health Saint Joseph Mercy Oakland Hospital
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Pontiac, Michigan, Stati Uniti, 48341
        • Reclutamento
        • Michigan Healthcare Professionals Pontiac
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • Pontiac, Michigan, Stati Uniti, 48341
        • Reclutamento
        • Trinity Health IHA Medical Group-Alice Gustafson Center
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Saginaw, Michigan, Stati Uniti, 48601
        • Reclutamento
        • MyMichigan Medical Center Saginaw
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Tawas City, Michigan, Stati Uniti, 48764
        • Reclutamento
        • MyMichigan Medical Center Tawas
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Warren, Michigan, Stati Uniti, 48093
        • Reclutamento
        • Henry Ford Madison Heights Hospital - Breast
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • Warren, Michigan, Stati Uniti, 48093
        • Reclutamento
        • Henry Ford Health Warren Hospital
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • Warren, Michigan, Stati Uniti, 48093
        • Reclutamento
        • Henry Ford Warren Hospital - GLCMS
        • Investigatore principale:
          • Rose A. Juhasz
        • Contatto:
      • Ypsilanti, Michigan, Stati Uniti, 48106
      • Ypsilanti, Michigan, Stati Uniti, 48197
        • Reclutamento
        • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
    • Minnesota
      • Burnsville, Minnesota, Stati Uniti, 55337
        • Reclutamento
        • Minnesota Oncology - Burnsville
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Coon Rapids, Minnesota, Stati Uniti, 55433
        • Reclutamento
        • Mercy Hospital
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Edina, Minnesota, Stati Uniti, 55435
        • Reclutamento
        • Fairview Southdale Hospital
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Maple Grove, Minnesota, Stati Uniti, 55369
        • Reclutamento
        • Fairview Clinics and Surgery Center Maple Grove
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Maplewood, Minnesota, Stati Uniti, 55109
        • Reclutamento
        • Minnesota Oncology Hematology PA-Maplewood
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Maplewood, Minnesota, Stati Uniti, 55109
        • Reclutamento
        • Saint John's Hospital - Healtheast
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Minneapolis, Minnesota, Stati Uniti, 55407
        • Reclutamento
        • Abbott-Northwestern Hospital
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Minneapolis, Minnesota, Stati Uniti, 55415
        • Reclutamento
        • Hennepin County Medical Center
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Monticello, Minnesota, Stati Uniti, 55362
        • Reclutamento
        • Monticello Cancer Center
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • New Ulm, Minnesota, Stati Uniti, 56073
        • Reclutamento
        • New Ulm Medical Center
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Princeton, Minnesota, Stati Uniti, 55371
        • Reclutamento
        • Fairview Northland Medical Center
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Robbinsdale, Minnesota, Stati Uniti, 55422
        • Reclutamento
        • North Memorial Medical Health Center
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Saint Louis Park, Minnesota, Stati Uniti, 55416
        • Reclutamento
        • Park Nicollet Clinic - Saint Louis Park
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Saint Paul, Minnesota, Stati Uniti, 55101
        • Reclutamento
        • Regions Hospital
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Saint Paul, Minnesota, Stati Uniti, 55102
        • Reclutamento
        • United Hospital
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Shakopee, Minnesota, Stati Uniti, 55379
        • Reclutamento
        • Saint Francis Regional Medical Center
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Stillwater, Minnesota, Stati Uniti, 55082
        • Reclutamento
        • Lakeview Hospital
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Waconia, Minnesota, Stati Uniti, 55387
        • Reclutamento
        • Ridgeview Medical Center
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Willmar, Minnesota, Stati Uniti, 56201
        • Reclutamento
        • Rice Memorial Hospital
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Woodbury, Minnesota, Stati Uniti, 55125
        • Reclutamento
        • Minnesota Oncology Hematology PA-Woodbury
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Wyoming, Minnesota, Stati Uniti, 55092
        • Reclutamento
        • Fairview Lakes Medical Center
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
    • Missouri
      • Ballwin, Missouri, Stati Uniti, 63011
        • Reclutamento
        • Mercy Oncology and Hematology - Clayton-Clarkson
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 888-446-3729
      • Bolivar, Missouri, Stati Uniti, 65613
        • Reclutamento
        • Central Care Cancer Center - Bolivar
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
      • Branson, Missouri, Stati Uniti, 65616
        • Reclutamento
        • Cox Cancer Center Branson
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 417-269-4520
      • Cape Girardeau, Missouri, Stati Uniti, 63703
        • Reclutamento
        • Saint Francis Medical Center
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 573-334-2230
          • Email: sfmc@sfmc.net
      • Cape Girardeau, Missouri, Stati Uniti, 63703
        • Reclutamento
        • Mercy Cancer Center - Cape Girardeau
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 888-446-3729
      • Farmington, Missouri, Stati Uniti, 63640
        • Reclutamento
        • Parkland Health Center - Farmington
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 314-996-5569
      • Joplin, Missouri, Stati Uniti, 64804
        • Reclutamento
        • Freeman Health System
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
      • Joplin, Missouri, Stati Uniti, 64804
        • Reclutamento
        • Mercy Hospital Joplin
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
      • Osage Beach, Missouri, Stati Uniti, 65065
        • Reclutamento
        • Lake Regional Hospital
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
      • Rolla, Missouri, Stati Uniti, 65401
        • Reclutamento
        • Mercy Clinic-Rolla-Cancer and Hematology
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 573-458-6379
      • Rolla, Missouri, Stati Uniti, 65401
        • Reclutamento
        • Phelps Health Delbert Day Cancer Institute
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
      • Saint Joseph, Missouri, Stati Uniti, 64506
        • Reclutamento
        • Heartland Regional Medical Center
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
      • Sainte Genevieve, Missouri, Stati Uniti, 63670
        • Reclutamento
        • Sainte Genevieve County Memorial Hospital
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 314-996-5569
      • Springfield, Missouri, Stati Uniti, 65804
        • Reclutamento
        • Mercy Hospital Springfield
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 417-269-4520
      • Springfield, Missouri, Stati Uniti, 65807
        • Reclutamento
        • CoxHealth South Hospital
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 417-269-4520
      • St Louis, Missouri, Stati Uniti, 63128
        • Reclutamento
        • Mercy Hospital South
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
      • St Louis, Missouri, Stati Uniti, 63141
        • Reclutamento
        • Mercy Hospital Saint Louis
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 314-251-7066
      • St Louis, Missouri, Stati Uniti, 63131
        • Reclutamento
        • Missouri Baptist Medical Center
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 314-996-5569
      • St Louis, Missouri, Stati Uniti, 63109
        • Reclutamento
        • Mercy Infusion Center - Chippewa
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 888-446-3729
      • Sullivan, Missouri, Stati Uniti, 63080
        • Reclutamento
        • Missouri Baptist Sullivan Hospital
        • Investigatore principale:
          • Bryan A. Faller
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 314-996-5569
      • Washington, Missouri, Stati Uniti, 63090
        • Reclutamento
        • Mercy Hospital Washington
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 636-390-1600
    • Montana
      • Anaconda, Montana, Stati Uniti, 59711
        • Reclutamento
        • Community Hospital of Anaconda
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
      • Billings, Montana, Stati Uniti, 59101
        • Reclutamento
        • Billings Clinic Cancer Center
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
      • Bozeman, Montana, Stati Uniti, 59715
        • Reclutamento
        • Bozeman Health Deaconess Hospital
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
      • Great Falls, Montana, Stati Uniti, 59405
        • Reclutamento
        • Great Falls Clinic
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
      • Great Falls, Montana, Stati Uniti, 59405
        • Reclutamento
        • Benefis Sletten Cancer Institute
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
      • Havre, Montana, Stati Uniti, 59501
        • Reclutamento
        • Hi-Line Sletten Cancer Center
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
      • Helena, Montana, Stati Uniti, 59601
        • Reclutamento
        • Benefis Helena Specialty Center
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
      • Kalispell, Montana, Stati Uniti, 59901
        • Reclutamento
        • Logan Health Medical Center
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
      • Missoula, Montana, Stati Uniti, 59802
        • Reclutamento
        • Saint Patrick Hospital - Community Hospital
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Missoula, Montana, Stati Uniti, 59804
        • Reclutamento
        • Community Medical Center
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
    • Nebraska
      • Grand Island, Nebraska, Stati Uniti, 68803
      • Kearney, Nebraska, Stati Uniti, 68847
      • Omaha, Nebraska, Stati Uniti, 68122
      • Omaha, Nebraska, Stati Uniti, 68124
        • Reclutamento
        • Alegent Health Bergan Mercy Medical Center
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
      • Omaha, Nebraska, Stati Uniti, 68130
    • North Carolina
      • Charlotte, North Carolina, Stati Uniti, 28204
        • Reclutamento
        • Novant Health Presbyterian Medical Center
        • Investigatore principale:
          • Kimberly S. Strickland
        • Contatto:
      • Huntersville, North Carolina, Stati Uniti, 28078
        • Reclutamento
        • Novant Health Cancer Institute - Huntersville
        • Investigatore principale:
          • Kimberly S. Strickland
        • Contatto:
      • Huntersville, North Carolina, Stati Uniti, 28078
        • Reclutamento
        • Novant Health Presbyterian Medical Center Huntersville
        • Investigatore principale:
          • Kimberly S. Strickland
        • Contatto:
      • Kernersville, North Carolina, Stati Uniti, 27284
        • Reclutamento
        • Novant Health Cancer Institute - Kernersville
        • Contatto:
        • Investigatore principale:
          • Judith O. Hopkins
      • Matthews, North Carolina, Stati Uniti, 28105
        • Reclutamento
        • Novant Health Cancer Institute - Matthews
        • Investigatore principale:
          • Kimberly S. Strickland
        • Contatto:
      • Matthews, North Carolina, Stati Uniti, 28105
        • Reclutamento
        • Matthews Radiation Oncology Center
        • Investigatore principale:
          • Kimberly S. Strickland
        • Contatto:
      • Mooresville, North Carolina, Stati Uniti, 28117
        • Reclutamento
        • Novant Health Cancer Institute - Mooresville
        • Investigatore principale:
          • Kimberly S. Strickland
        • Contatto:
      • Mount Airy, North Carolina, Stati Uniti, 27030
        • Reclutamento
        • Novant Health Cancer Institute - Mount Airy
        • Contatto:
        • Investigatore principale:
          • Judith O. Hopkins
      • Salisbury, North Carolina, Stati Uniti, 28144
        • Reclutamento
        • Rowan Regional Medical Center
        • Contatto:
        • Investigatore principale:
          • Kimberly S. Strickland
      • Salisbury, North Carolina, Stati Uniti, 28144
        • Reclutamento
        • Novant Health Cancer Institute - Rowan
        • Investigatore principale:
          • Kimberly S. Strickland
        • Contatto:
      • Thomasville, North Carolina, Stati Uniti, 27360
        • Reclutamento
        • Novant Health Cancer Institute - Thomasville
        • Investigatore principale:
          • Judith O. Hopkins
        • Contatto:
      • Wilmington, North Carolina, Stati Uniti, 28401
        • Reclutamento
        • Novant Health New Hanover Regional Medical Center
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 910-342-3000
        • Investigatore principale:
          • Lindsey Prochaska
      • Winston-Salem, North Carolina, Stati Uniti, 27103
        • Reclutamento
        • Novant Health Forsyth Medical Center
        • Investigatore principale:
          • Judith O. Hopkins
        • Contatto:
    • Ohio
      • Cincinnati, Ohio, Stati Uniti, 45220
      • Cincinnati, Ohio, Stati Uniti, 45242
      • Cincinnati, Ohio, Stati Uniti, 45247
      • Cincinnati, Ohio, Stati Uniti, 45255
    • Oklahoma
      • Oklahoma City, Oklahoma, Stati Uniti, 73120
        • Reclutamento
        • Mercy Hospital Oklahoma City
        • Investigatore principale:
          • Jay W. Carlson
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 405-752-3402
    • Oregon
      • Baker City, Oregon, Stati Uniti, 97814
        • Reclutamento
        • Saint Alphonsus Cancer Care Center-Baker City
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Bend, Oregon, Stati Uniti, 97701
        • Reclutamento
        • Saint Charles Health System
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Clackamas, Oregon, Stati Uniti, 97015
        • Reclutamento
        • Clackamas Radiation Oncology Center
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Coos Bay, Oregon, Stati Uniti, 97420
        • Sospeso
        • Bay Area Hospital
      • Hood River, Oregon, Stati Uniti, 97031
        • Reclutamento
        • Providence Hood River Memorial Hospital
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Newberg, Oregon, Stati Uniti, 97132
        • Reclutamento
        • Providence Newberg Medical Center
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Ontario, Oregon, Stati Uniti, 97914
        • Reclutamento
        • Saint Alphonsus Cancer Care Center-Ontario
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Oregon City, Oregon, Stati Uniti, 97045
        • Reclutamento
        • Providence Willamette Falls Medical Center
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Portland, Oregon, Stati Uniti, 97213
        • Reclutamento
        • Providence Portland Medical Center
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Portland, Oregon, Stati Uniti, 97225
        • Reclutamento
        • Providence Saint Vincent Medical Center
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Redmond, Oregon, Stati Uniti, 97756
        • Reclutamento
        • Saint Charles Health System-Redmond
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 541-706-2909
    • Pennsylvania
      • Allentown, Pennsylvania, Stati Uniti, 18103
        • Reclutamento
        • Lehigh Valley Hospital-Cedar Crest
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Bethlehem, Pennsylvania, Stati Uniti, 18017
        • Reclutamento
        • Lehigh Valley Hospital - Muhlenberg
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • East Stroudsburg, Pennsylvania, Stati Uniti, 18301
        • Reclutamento
        • Pocono Medical Center
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
      • Hazleton, Pennsylvania, Stati Uniti, 18201
        • Reclutamento
        • Lehigh Valley Hospital-Hazleton
        • Contatto:
        • Investigatore principale:
          • Rose A. Juhasz
    • South Carolina
      • Charleston, South Carolina, Stati Uniti, 29425
        • Reclutamento
        • Medical University of South Carolina
        • Contatto:
        • Investigatore principale:
          • Kevin S. Hughes
    • Texas
      • San Antonio, Texas, Stati Uniti, 78229
        • Reclutamento
        • University of Texas Health Science Center at San Antonio
        • Contatto:
        • Investigatore principale:
          • Anne-Marie R. Langevin
    • Virginia
      • Mechanicsville, Virginia, Stati Uniti, 23116
        • Reclutamento
        • Bon Secours Memorial Regional Medical Center
        • Contatto:
        • Investigatore principale:
          • William J. Irvin
      • Midlothian, Virginia, Stati Uniti, 23114
        • Reclutamento
        • Bon Secours Saint Francis Medical Center
        • Contatto:
        • Investigatore principale:
          • William J. Irvin
      • Richmond, Virginia, Stati Uniti, 23235
        • Reclutamento
        • VCU Massey Cancer Center at Stony Point
        • Contatto:
        • Investigatore principale:
          • Mary H. Hackney
      • Richmond, Virginia, Stati Uniti, 23226
        • Reclutamento
        • Bon Secours Saint Mary's Hospital
        • Contatto:
        • Investigatore principale:
          • William J. Irvin
      • Richmond, Virginia, Stati Uniti, 23298
        • Reclutamento
        • VCU Massey Comprehensive Cancer Center
        • Investigatore principale:
          • Mary H. Hackney
        • Contatto:
      • South Hill, Virginia, Stati Uniti, 23970
        • Reclutamento
        • VCU Community Memorial Health Center
        • Contatto:
        • Investigatore principale:
          • Mary H. Hackney
    • Washington
      • Aberdeen, Washington, Stati Uniti, 98520
        • Reclutamento
        • Providence Regional Cancer System-Aberdeen
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Bellingham, Washington, Stati Uniti, 98225
        • Reclutamento
        • PeaceHealth Saint Joseph Medical Center
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Centralia, Washington, Stati Uniti, 98531
        • Reclutamento
        • Providence Regional Cancer System-Centralia
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Edmonds, Washington, Stati Uniti, 98026
        • Reclutamento
        • Swedish Cancer Institute-Edmonds
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Everett, Washington, Stati Uniti, 98201
        • Reclutamento
        • Providence Regional Cancer Partnership
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Everett, Washington, Stati Uniti, 98201
        • Reclutamento
        • Providence Swedish Cancer Institute
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
          • Site Public Contact
          • Numero di telefono: 855-922-6237
      • Issaquah, Washington, Stati Uniti, 98029
        • Reclutamento
        • Swedish Cancer Institute-Issaquah
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Kennewick, Washington, Stati Uniti, 99336
        • Reclutamento
        • Kadlec Clinic Hematology and Oncology
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Lacey, Washington, Stati Uniti, 98503
        • Reclutamento
        • Providence Regional Cancer System-Lacey
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Longview, Washington, Stati Uniti, 98632
        • Reclutamento
        • PeaceHealth Saint John Medical Center
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Mount Vernon, Washington, Stati Uniti, 98274
      • Seattle, Washington, Stati Uniti, 98122
        • Reclutamento
        • Swedish Medical Center-First Hill
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Seattle, Washington, Stati Uniti, 98107
        • Reclutamento
        • Swedish Medical Center-Ballard Campus
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Seattle, Washington, Stati Uniti, 98122-5711
        • Reclutamento
        • Swedish Medical Center-Cherry Hill
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Sedro-Woolley, Washington, Stati Uniti, 98284
        • Reclutamento
        • PeaceHealth United General Medical Center
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Silverdale, Washington, Stati Uniti, 98383
        • Reclutamento
        • Saint Joseph Medical Center Hematology and Oncology - Silverdale
        • Investigatore principale:
          • Loretta J. Nastoupil
        • Contatto:
      • Spokane, Washington, Stati Uniti, 99202
        • Reclutamento
        • Cancer Care Northwest - Spokane South
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Spokane, Washington, Stati Uniti, 99216
        • Reclutamento
        • Cancer Care Northwest-Valley
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Spokane, Washington, Stati Uniti, 99218
        • Reclutamento
        • Cancer Care Northwest-North Spokane
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Vancouver, Washington, Stati Uniti, 98664
        • Reclutamento
        • PeaceHealth Southwest Medical Center
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
      • Walla Walla, Washington, Stati Uniti, 99362
        • Reclutamento
        • Providence Saint Mary Regional Cancer Center
        • Investigatore principale:
          • Alison K. Conlin
        • Contatto:
    • Wisconsin
      • Burlington, Wisconsin, Stati Uniti, 53105
        • Reclutamento
        • Aurora Cancer Care-Southern Lakes VLCC
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Cudahy, Wisconsin, Stati Uniti, 53110
        • Reclutamento
        • Aurora Saint Luke's South Shore
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Germantown, Wisconsin, Stati Uniti, 53022
        • Reclutamento
        • Aurora Health Care Germantown Health Center
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Grafton, Wisconsin, Stati Uniti, 53024
        • Reclutamento
        • Aurora Cancer Care-Grafton
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Green Bay, Wisconsin, Stati Uniti, 54311
        • Reclutamento
        • Aurora BayCare Medical Center
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Green Bay, Wisconsin, Stati Uniti, 54301
        • Reclutamento
        • Saint Vincent Hospital Cancer Center Green Bay
        • Investigatore principale:
          • Anthony J. Jaslowski
        • Contatto:
      • Green Bay, Wisconsin, Stati Uniti, 54303
        • Reclutamento
        • Saint Vincent Hospital Cancer Center at Saint Mary's
        • Investigatore principale:
          • Anthony J. Jaslowski
        • Contatto:
      • Kenosha, Wisconsin, Stati Uniti, 53142
        • Reclutamento
        • Aurora Cancer Care-Kenosha South
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Marinette, Wisconsin, Stati Uniti, 54143
        • Reclutamento
        • Aurora Bay Area Medical Group-Marinette
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Milwaukee, Wisconsin, Stati Uniti, 53209
        • Reclutamento
        • Aurora Cancer Care-Milwaukee
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Milwaukee, Wisconsin, Stati Uniti, 53215
        • Reclutamento
        • Aurora Saint Luke's Medical Center
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Milwaukee, Wisconsin, Stati Uniti, 53233
        • Reclutamento
        • Aurora Sinai Medical Center
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • New Richmond, Wisconsin, Stati Uniti, 54017
        • Reclutamento
        • Cancer Center of Western Wisconsin
        • Contatto:
        • Investigatore principale:
          • Margaret B. Nolan
      • Oconto Falls, Wisconsin, Stati Uniti, 54154
        • Reclutamento
        • Saint Vincent Hospital Cancer Center at Oconto Falls
        • Investigatore principale:
          • Anthony J. Jaslowski
        • Contatto:
      • Oshkosh, Wisconsin, Stati Uniti, 54904
        • Reclutamento
        • Vince Lombardi Cancer Clinic - Oshkosh
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Racine, Wisconsin, Stati Uniti, 53406
        • Reclutamento
        • Aurora Cancer Care-Racine
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Sheboygan, Wisconsin, Stati Uniti, 53081
        • Reclutamento
        • Vince Lombardi Cancer Clinic-Sheboygan
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Sheboygan, Wisconsin, Stati Uniti, 53081
        • Reclutamento
        • Saint Vincent Hospital Cancer Center at Sheboygan
        • Investigatore principale:
          • Anthony J. Jaslowski
        • Contatto:
      • Sheboygan, Wisconsin, Stati Uniti, 53081
        • Reclutamento
        • Sheboygan Physicians Group
        • Investigatore principale:
          • Anthony J. Jaslowski
        • Contatto:
      • Sturgeon Bay, Wisconsin, Stati Uniti, 54235-1495
        • Reclutamento
        • Saint Vincent Hospital Cancer Center at Sturgeon Bay
        • Investigatore principale:
          • Anthony J. Jaslowski
        • Contatto:
      • Summit, Wisconsin, Stati Uniti, 53066
        • Reclutamento
        • Aurora Medical Center in Summit
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Two Rivers, Wisconsin, Stati Uniti, 54241
        • Reclutamento
        • Vince Lombardi Cancer Clinic-Two Rivers
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • Wauwatosa, Wisconsin, Stati Uniti, 53226
        • Reclutamento
        • Aurora Cancer Care-Milwaukee West
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
      • West Allis, Wisconsin, Stati Uniti, 53227
        • Reclutamento
        • Aurora West Allis Medical Center
        • Contatto:
        • Investigatore principale:
          • Sigrun Hallmeyer
    • Wyoming
      • Cheyenne, Wyoming, Stati Uniti, 82001
        • Reclutamento
        • Memorial Hospital of Laramie County
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:
      • Cody, Wyoming, Stati Uniti, 82414
        • Reclutamento
        • Billings Clinic-Cody
        • Investigatore principale:
          • John M. Schallenkamp
        • Contatto:

Criteri di partecipazione

I ricercatori cercano persone che corrispondano a una certa descrizione, chiamata criteri di ammissibilità. Alcuni esempi di questi criteri sono le condizioni generali di salute di una persona o trattamenti precedenti.

Criteri di ammissibilità

Età idonea allo studio

18 anni e precedenti (Adulto, Adulto più anziano)

Accetta volontari sani

Sì

Sessi ammissibili allo studio

Tutto

Descrizione

  • PATIENTS: Age ≥ 18 years and ≤ 39 years at the time of enrollment
  • PATIENTS: AYA cancer patients and survivors. This includes patients at any stage of diagnosis (e.g., newly diagnosed, in treatment, in survivorship) and a cancer diagnosis (including pediatric cancers) at any age ≤ 39 years old. Given targeted therapies for BRCA+ and microsatellite instability (MSI)-high/Lynch Syndrome patients and benefit to relatives, patients with metastatic cancer are included. Any history of cancer, regardless of being in treatment or not
  • PATIENTS: Language: In order to complete the mandatory patient-completed measures and receive genetic education and counseling, participants must be able to speak and read English or Spanish
  • PATIENTS: No known diagnosis of dementia or cognitive impairment. Persons with impaired decision-making capacity are ineligible as they need to be able to understand genetic test results, its implications for the patient and family, and explain genetic test results to their family members
  • PATIENTS: No persons with a known psychiatric or documented developmental disorder that affects cognitive or emotional functions to the extent that the capacity for judgment and reason is significantly diminished, such that they cannot participate based on the judgment of the treating physician
  • PATIENTS: Participants must meet National Comprehensive Cancer Network (NCCN) guidelines for genetic testing assessment provided by Penn Telegenetics by the Eligibility Verification Assessment (EVA) chatbot, or paper forms and genetic counselor's review
  • NON-PATIENT PARTICIPANT: Non-patient participants eligible for this study include: oncology providers, members of the care team and clinic staff, genetic counselors, and insurers (i.e., people who work in financial services and/or for insurance companies) who participate in oncology care among AYA in community for this study
  • NON-PATIENT PARTICIPANT: Age ≥ 18 years
  • NON-PATIENT PARTICIPANT: Non-patient participants must be able to speak and read English or Spanish in order to participate in the key informant interviews

Piano di studio

Questa sezione fornisce i dettagli del piano di studio, compreso il modo in cui lo studio è progettato e ciò che lo studio sta misurando.

Come è strutturato lo studio?

Dettagli di progettazione

  • Scopo principale: Ricerca sui servizi sanitari
  • Assegnazione: Randomizzato
  • Modello interventistico: Assegnazione parallela
  • Mascheramento: Nessuno (etichetta aperta)

Armi e interventi

Gruppo di partecipanti / Arm
Intervento / Trattamento
Comparatore attivo: Arm I (standard remote genetic services)

Patients attend a standard of care telehealth visit with a genetic counselor for pretest genetic education. Patients then undergo standard of care genetic testing and attend a telehealth visit with a genetic counselor for disclosure of results.
Altro: Survey Administration

Ancillary studies

Altro: Telemedicine

Undergo telehealth visit with genetic counselor for pretest genetic education

Altro: Genetic Testing

Complete standard of care genetic testing

Altro: Telemedicine

Undergo telehealth visit with genetic counselor for disclosure of results
Sperimentale: Arm II (Genetic Journey Chatbot)

Patients receive access to the Genetic Journey Chatbot and choose to complete digital pre-test genetic education via the digital tool or via telehealth visit with a genetic counselor. Via the chatbot, patients may request a telehealth visit with a genetic counselor at any time to answer unresolved questions. Patients then undergo standard of care genetic testing and attend a telehealth visit with a genetic counselor for disclosure of results. The chatbot remains available to answer questions, assess barriers, and provide reminders for next steps during the testing period.
Altro: Survey Administration

Ancillary studies

Altro: Telemedicine

Undergo telehealth visit with genetic counselor for pretest genetic education

Altro: Genetic Testing

Complete standard of care genetic testing

Altro: Telemedicine

Undergo telehealth visit with genetic counselor for disclosure of results

Altro: Internet-Based Intervention

Receive access to Genetic Journey Chatbot

Altro: Educational Intervention

Complete digital pre-test genetic education

Comportamentale: Patient Navigation

Utilize chatbot to answer questions, assess barriers, and provide reminders for next steps during the testing period

Altro: Interview

Complete interview

Cosa sta misurando lo studio?

Misure di risultato primarie

Misura del risultato
Misura Descrizione
Lasso di tempo
Uptake of genetic counseling
Lasso di tempo: Within 6 months of baseline

Defined as a binary outcome of whether an adolescent or young adult (AYA) underwent genetic counseling within 6 months post completion of the baseline survey. Will be compared between randomized arms using Cochran-Mantel-Haenszel (CMH) tests stratified by gender and a Bonferroni correction will be applied to control family-wise type I error.
Within 6 months of baseline
Uptake of genetic testing
Lasso di tempo: Within 6 months of baseline

Defined as a binary outcome of whether an AYA underwent genetic testing within 6 months post completion of the baseline survey. Will be compared between randomized arms using CMH tests stratified by gender and a Bonferroni correction will be applied to control family-wise type I error.
Within 6 months of baseline

Misure di risultato secondarie

Misura del risultato
Misura Descrizione
Lasso di tempo
Knowledge of genetic disease
Lasso di tempo: Up to 42 months post registration

Obtained from the KnowGene scale. Will be compared using non-inferiority testing with the equivalent of a 0.3 standard deviation (SD) non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics.
Up to 42 months post registration
Test result recall
Lasso di tempo: Up to 42 months post registration

Measured via the Test Result Recall scale. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for each secondary endpoint at T2 (the primary time point of interest for the secondary analyses) will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics.
Up to 42 months post registration
Perceptions of genetic disease
Lasso di tempo: Up to 42 months post registration

Measured via the Perceived Risk scale. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics.
Up to 42 months post registration
Anxiety
Lasso di tempo: Up to 42 months post registration

Measured via Patient Reported Outcome Measurement Information System (PROMIS) anxiety score. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics.
Up to 42 months post registration
Depression
Lasso di tempo: Up to 42 months post registration

Measured via PROMIS Depression score. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics.
Up to 42 months post registration
Disease-specific distress
Lasso di tempo: Up to 42 months post registration

Measured via the Revised Impact of Events Scale score. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics.
Up to 42 months post registration
Impact of cancer risk
Lasso di tempo: Up to 42 months post registration

Measured via the Multi-dimensional Impact of Cancer Risk Assessment score. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit or each secondary endpoint at T2 (the primary time point of interest for the secondary analyses) will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics
Up to 42 months post registration
Satisfaction with genetic services
Lasso di tempo: Up to 30 months post registration

Measured via the Satisfaction with Genetic Services scale. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit or each secondary endpoint at T2 (the primary time point of interest for the secondary analyses) will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD.
Up to 30 months post registration
Attitude toward genetic testing
Lasso di tempo: Up to 24 months post registration

Measured via Attitudes Toward Genetic Testing scale. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit or each secondary endpoint at T2 (the primary time point of interest for the secondary analyses) will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD.
Up to 24 months post registration
Lifestyle behaviors
Lasso di tempo: Up to 42 months post registration

Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics.
Up to 42 months post registration
Health behaviors
Lasso di tempo: Up to 42 months post registration

Measured via the Screening Health behaviors score. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics.
Up to 42 months post registration
Communication to at-risk relatives
Lasso di tempo: Up to 42 months post registration

Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics.
Up to 42 months post registration
Genetic counselor time
Lasso di tempo: Up to 24 months post registration

o Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics.
Up to 24 months post registration
Testing costs
Lasso di tempo: Up to 36 months post registration

Measured by 2 patient reported items
Up to 36 months post registration
Costs of the intervention
Lasso di tempo: Up to 42 months post registration

o Will be estimated from a societal perspective, including direct medical and nonmedical costs. These include intervention and chatbot hosting, telecommunication services, personnel and patient time. Information to estimate intervention costs collected from study billing and payment records (e.g. website hosting, chatbot usage and time, videoconferencing and phone usage) and telegenetic staff logs (personnel time). The cost of personnel time will be based on institution-specific salaries, including fringe benefits. In sensitivity analysis, will substitute site-specific salary information with national average wage rates for the relevant occupational categories. Information about other out-of-pocket costs for testing (e.g. copayments) will be obtained through participant surveys. Patient time costs will be valued using national average wage rates for participant-specified occupations.
Up to 42 months post registration

Collaboratori e investigatori

Qui è dove troverai le persone e le organizzazioni coinvolte in questo studio.

Sponsor

Alliance for Clinical Trials in Oncology

Collaboratori

National Cancer Institute (NCI)

Investigatori

  • Cattedra di studio: Angela Bradbury, MD, Alliance for Clinical Trials in Oncology

Studiare le date dei record

Queste date tengono traccia dell'avanzamento della registrazione dello studio e dell'invio dei risultati di sintesi a ClinicalTrials.gov. I record degli studi e i risultati riportati vengono esaminati dalla National Library of Medicine (NLM) per assicurarsi che soddisfino specifici standard di controllo della qualità prima di essere pubblicati sul sito Web pubblico.

Studia le date principali

Inizio studio (Effettivo)

10 dicembre 2025

Completamento primario (Stimato)

28 aprile 2028

Completamento dello studio (Stimato)

30 aprile 2029

Date di iscrizione allo studio

Primo inviato

24 giugno 2025

Primo inviato che soddisfa i criteri di controllo qualità

21 luglio 2025

Primo Inserito (Effettivo)

29 luglio 2025

Aggiornamenti dei record di studio

Ultimo aggiornamento pubblicato (Effettivo)

4 novembre 2026

Ultimo aggiornamento inviato che soddisfa i criteri QC

2 novembre 2026

Ultimo verificato

1 novembre 2026

Maggiori informazioni

Termini relativi a questo studio

Termini MeSH pertinenti aggiuntivi

Altri numeri di identificazione dello studio

  • A232301CD
  • NCI-2025-02152 (Altro identificatore: NCI Clinical Trial Reporting Program)

Piano per i dati dei singoli partecipanti (IPD)

Hai intenzione di condividere i dati dei singoli partecipanti (IPD)?

INDECISO

Informazioni su farmaci e dispositivi, documenti di studio

Studia un prodotto farmaceutico regolamentato dalla FDA degli Stati Uniti

No

Studia un dispositivo regolamentato dalla FDA degli Stati Uniti

No

Queste informazioni sono state recuperate direttamente dal sito web clinicaltrials.gov senza alcuna modifica. In caso di richieste di modifica, rimozione o aggiornamento dei dettagli dello studio, contattare register@clinicaltrials.gov. Non appena verrà implementata una modifica su clinicaltrials.gov, questa verrà aggiornata automaticamente anche sul nostro sito web .

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