Questa pagina è stata tradotta automaticamente e l'accuratezza della traduzione non è garantita. Si prega di fare riferimento al Versione inglese per un testo di partenza.

Comparative Clinical Assessment of Charcoal and Conventional Toothbrushes

27 aprile 2026 aggiornato da: yomna sayed khallaf, Cairo University

Evaluation Of Plaque And Micro-Stain Removal Efficacy Of Charcoal-Infused Versus Conventional Tooth Brushes In Egyptian Adults: A Randomized Clinical Trial

Oral hygiene practices are fundamental to maintaining oral health, preventing dental plaque accumulation, halitosis, stains, gingival and periodontal diseases, and improving overall quality of life. Dental plaque plays a central role in the initiation of caries and periodontal disease by lowering enamel surface pH and promoting hydroxyapatite dissolution. Toothbrushing with toothpaste remains the most widely accepted and effective method for mechanical plaque control, with its efficacy influenced by toothbrush design, brushing technique, and duration. Recently, charcoal-infused toothbrushes have been introduced as an alternative oral hygiene aid.

These brushes incorporate binchotan charcoal into nylon bristles, purportedly offering antimicrobial, deodorizing, and stain-removal properties by increasing oral pH, reducing bacterial load, and absorbing stain causing compounds. Despite growing commercial interest, scientific evidence supporting their clinical efficacy remains limited. Therefore, this randomized controlled clinical trial aims to evaluate and compare the effectiveness of charcoal-infused toothbrushes versus conventional toothbrushes in plaque reduction and stain removal among Egyptian adults. Plaque levels will be assessed using the Turesky and Gilmore modification of the Quigley-Hein Plaque Index, while stain removal efficacy will be evaluated through spectrophotometric color measurements using a Vita Easyshade device. Outcomes will be recorded at baseline and after four weeks of twice-daily brushing with standardized fluoride toothpaste. This study addresses a clear gap in the literature by providing clinical evidence on the effectiveness of charcoal-containing toothbrushes, thereby supporting evidence-based recommendations for modern oral hygiene practices.

Panoramica dello studio

Stato

Completato

Condizioni

Intervento / Trattamento

Descrizione dettagliata

Oral hygiene practices are essential for maintaining oral health and preventing a wide range of conditions, including dental plaque accumulation, halitosis, extrinsic staining, gingival inflammation, and periodontal diseases, all of which can significantly affect an individual's quality of life. Among these factors, dental plaque is considered the primary etiological agent in the development of both dental caries and periodontal disease. It contributes to disease progression by facilitating bacterial colonization, lowering the pH at the tooth surface, and promoting the demineralization of enamel through hydroxyapatite dissolution.

Toothbrushing with toothpaste remains the cornerstone of daily oral hygiene and the most widely accepted method for mechanical plaque control. Its effectiveness depends on multiple variables, including toothbrush design (such as bristle type and arrangement), brushing technique, frequency, and duration. In addition to plaque removal, toothbrushing also plays an important role in controlling extrinsic stains, thereby contributing to improved dental esthetics.

In recent years, charcoal-infused toothbrushes have been introduced as an alternative oral hygiene aid and have gained increasing popularity in the consumer market. These toothbrushes typically incorporate activated charcoal-often derived from binchotan charcoal-into nylon bristles. Activated charcoal is characterized by a highly porous structure and large surface area, which theoretically enhances its ability to adsorb organic compounds. Manufacturers claim that charcoal-infused toothbrushes offer multiple benefits, including antimicrobial activity, deodorizing effects, and improved stain removal. These effects are proposed to occur through mechanisms such as increasing oral pH, reducing bacterial load, and binding stain-causing chromogens on the tooth surface.

Despite these claims and widespread commercial promotion, the scientific evidence supporting the clinical effectiveness of charcoal-infused toothbrushes remains limited and inconclusive. Most available studies have focused on charcoal-containing dentifrices rather than toothbrushes, and clinical trials-particularly those involving adult populations-are scarce. Furthermore, existing data show inconsistent findings regarding their superiority over conventional toothbrushes in plaque control and whitening efficacy.

Therefore, the present randomized controlled clinical trial was designed to evaluate and compare the effectiveness of charcoal-infused toothbrushes versus conventional nylon toothbrushes in reducing dental plaque and removing extrinsic stains among Egyptian adults. Plaque accumulation was assessed using the Turesky and Gilmore modification of the Quigley-Hein Plaque Index, a validated and widely used clinical index. Stain removal efficacy was evaluated objectively using spectrophotometric color measurements (ΔE, ΔL*, Δb*) obtained with a Vita Easyshade device, allowing for precise and reproducible assessment of tooth color changes.

All participants were instructed to perform twice-daily toothbrushing using a standardized fluoride toothpaste to control for confounding variables. Clinical outcomes were recorded at baseline and after a four-week follow-up period. By employing a randomized controlled design and objective measurement tools, this study aims to provide reliable clinical evidence regarding the actual benefits of charcoal-infused toothbrushes.

This study addresses a significant gap in the literature by being among the first to evaluate the stain removal efficacy of charcoal toothbrushes in an adult population within a clinical setting. The findings are expected to contribute to evidence-based recommendations and guide both clinicians and patients in making informed decisions regarding the use of modern oral hygiene products

Tipo di studio

Interventistico

Iscrizione (Effettivo)

36

Fase

  • Non applicabile

Contatti e Sedi

Questa sezione fornisce i recapiti di coloro che conducono lo studio e informazioni su dove viene condotto lo studio.

Luoghi di studio

      • Cairo, Egitto
        • Faculty of Dentistry Cairo University

Criteri di partecipazione

I ricercatori cercano persone che corrispondano a una certa descrizione, chiamata criteri di ammissibilità. Alcuni esempi di questi criteri sono le condizioni generali di salute di una persona o trattamenti precedenti.

Criteri di ammissibilità

Età idonea allo studio

  • Adulto

Accetta volontari sani

Sì

Descrizione

Inclusion Criteria:

  • Subjects who will be given a consent to participate in the study, between 21 to 50 years old, with an original plaque score recorded above 2, and presence of at least twenty long lasting natural teeth (excluding wisdom tooth, teeth with orthodontic appliances) were included in the study.

Exclusion Criteria:

  • Subjects with any physical constraints that might prevent normal oral hygiene procedures, history of sensitivity to toothpaste, use of interdental aids (interdental floss, mouth rinses, etc), pregnant or breastfeeding females, subjects under medication such as anti inflammatory, antiepileptic and antihypertensive, medically compromised patients (systemic diseases such as cardiovascular disease, diabetes, etc), evidences of gingival or periodontal diseases or trauma at baseline, any lesion of hard and soft tissue, were excluded from the study.

Piano di studio

Questa sezione fornisce i dettagli del piano di studio, compreso il modo in cui lo studio è progettato e ciò che lo studio sta misurando.

Come è strutturato lo studio?

Dettagli di progettazione

  • Scopo principale: Terapia di supporto
  • Assegnazione: Randomizzato
  • Modello interventistico: Assegnazione parallela
  • Mascheramento: Separare

Armi e interventi

Gruppo di partecipanti / Arm
Intervento / Trattamento
Comparatore attivo: conventional toothbrush
Participants in the control group used a conventional nylon-bristled toothbrush . They were instructed to brush twice daily for 2 minutes using a standardized fluoride toothpaste and identical oral hygiene instructions. The use of any additional oral hygiene or whitening products was also prohibited throughout the 4-week study period.
Participants were randomly assigned to either a charcoal-infused toothbrush (test group) or a conventional nylon toothbrush (control group). Both groups were instructed to brush twice daily for 2 minutes using standardized fluoride toothpaste and to follow the same brushing instructions provided at baseline. No additional oral hygiene aids or whitening products were allowed during the 4-week study period. Compliance was encouraged through regular reminders, and clinical assessments were performed at baseline and after 4 weeks.
Sperimentale: charcoal toothbrush
Participants in the test group used a charcoal-infused toothbrush containing activated charcoal incorporated into nylon bristles. They were instructed to brush twice daily for 2 minutes using a standardized fluoride toothpaste and the same standardized brushing instructions provided at baseline. No additional oral hygiene aids or whitening products were permitted during the 4-week study period.
Participants were randomly assigned to either a charcoal-infused toothbrush (test group) or a conventional nylon toothbrush (control group). Both groups were instructed to brush twice daily for 2 minutes using standardized fluoride toothpaste and to follow the same brushing instructions provided at baseline. No additional oral hygiene aids or whitening products were allowed during the 4-week study period. Compliance was encouraged through regular reminders, and clinical assessments were performed at baseline and after 4 weeks.

Cosa sta misurando lo studio?

Misure di risultato primarie

Misura del risultato
Misura Descrizione
Lasso di tempo
The plaque score
Lasso di tempo: 4 weeks
(Turesky and Gilmore modification of Quigley Hein plaque index)
4 weeks

Misure di risultato secondarie

Misura del risultato
Misura Descrizione
Lasso di tempo
Stain removal efficacy , measured by color change
Lasso di tempo: 4 weeks
Vita Easyshade spectrophotometer
4 weeks

Collaboratori e investigatori

Qui è dove troverai le persone e le organizzazioni coinvolte in questo studio.

Studiare le date dei record

Queste date tengono traccia dell'avanzamento della registrazione dello studio e dell'invio dei risultati di sintesi a ClinicalTrials.gov. I record degli studi e i risultati riportati vengono esaminati dalla National Library of Medicine (NLM) per assicurarsi che soddisfino specifici standard di controllo della qualità prima di essere pubblicati sul sito Web pubblico.

Studia le date principali

Inizio studio (Effettivo)

1 gennaio 2026

Completamento primario (Effettivo)

1 febbraio 2026

Completamento dello studio (Effettivo)

20 febbraio 2026

Date di iscrizione allo studio

Primo inviato

27 aprile 2026

Primo inviato che soddisfa i criteri di controllo qualità

27 aprile 2026

Primo Inserito (Effettivo)

4 maggio 2026

Aggiornamenti dei record di studio

Ultimo aggiornamento pubblicato (Effettivo)

4 maggio 2026

Ultimo aggiornamento inviato che soddisfa i criteri QC

27 aprile 2026

Ultimo verificato

1 aprile 2026

Maggiori informazioni

Termini relativi a questo studio

Informazioni su farmaci e dispositivi, documenti di studio

Studia un prodotto farmaceutico regolamentato dalla FDA degli Stati Uniti

No

Studia un dispositivo regolamentato dalla FDA degli Stati Uniti

No

Queste informazioni sono state recuperate direttamente dal sito web clinicaltrials.gov senza alcuna modifica. In caso di richieste di modifica, rimozione o aggiornamento dei dettagli dello studio, contattare register@clinicaltrials.gov. Non appena verrà implementata una modifica su clinicaltrials.gov, questa verrà aggiornata automaticamente anche sul nostro sito web .

Sottoscrivi