Italian University implementes the PREP2 Algorithm into clinical practice
Photo by Cristian Newman
The University of Ferrara is conducting the clinical trial of the Implementation of PREP2 Algorithm into Clinical Practice (PRESTO).
Stroke is a worldwide major cause of disability with great social and economic burdens. The recovery of motor function is crucial for the patient to regain independence and quality of life. Identifying early predictors of motor recovery and outcomes is useful for planning personalized rehabilitation programs and increasing their efficiency. However, making predictions using a single clinical assessment is often difficult and a combination of multiple tools is required. In the last decades, were validated two predictive algorithms for upper limb function and independent walking that can be easily implemented into clinical practice with the aim of increasing knowledge on expected outcome after stroke in patients, families and rehabilitation teams. This will be the first trial that will test the implementation of such tools in a rehabilitation setting in Italy.
The patients with diagnosis of stroke and new upper and/or lower limb weakness can be enrolled to this study.
Patients with the following pathologies:
- cerebellar or bilateral stroke;
- contraindication to TMS;
- cognitive or communication impairment precluding informed consent;
- assisted walking prior to admission;
- severe medical conditions.
are excluded from participation.
The location of the study is Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, Ferrara, Emilia Romagna, Italy, 44124.
The University of Ferrara (Italian: Università degli Studi di Ferrara) is the main university of the city of Ferrara in the Emilia-Romagna region of northern Italy.
The CIVR (Comitato di Indirizzo per la Valutazione della Ricerca, or Directory Committee for the Evaluation of Research), according to a public report of 2007, has rated the University of Ferrara as the best Italian university for the applied exploitation of research. In order to produce these results, the CIVR has taken into consideration numerous data such as patents registered in Italy and abroad, the research collaborations between the university business and academic spin-offs.
The page dedicated to this clinical trial can be found here: https://ichgcp.net/clinical-trials-registry/NCT04637984
