Recolonisation of Bacteria in Hands and Possible Bacterial Leakage From Glove Cuff in Cardiac Surgery
2017年4月3日 更新者:Camilla Wistrand、Örebro University, Sweden
Recolonisation of Bacteria in Hands and Possible Bacterial Leakage From Glove Cuff in Cardiac Surgery. Differences in Microbial Flora and Recolonisation Between Hospital and Non-hospital Persons. A Controlled Clinical Trial.
This study aims to investigate if recolonisation of the hand flora occur after surgical hand washing and is there a bacterial leakage at the glove cuff site in cardiac surgery?
Also investigate if thera are differences in microbial flora and recolonisation between hospital and non-hospital persons.
調査の概要
詳細な説明
With emerging antibiotic resistant bacteria it is necessary to try to prevent surgical site infections (SSIs).Not only because of suffering and death but also because of increased costs.
For a deep sternal infection the cost can be doubled or even tripled.
Sternal wound complications can occur from low numbers up to almost 10%, with different severity, depending on follow up routines In an intraoperative environment causative bacteria often originate from either patient or surgical team.
One of many preventing measures is to keep patients and surgical members as sterile as possible when it´s the number of bacteria that overcome the host defense that lead to infection.
The most common bacteria causing sternal infection is Coagulase negative staphylococci (CoNS) 46% Staphylococcus aureus, 26% and gram- negative bacteria, 18%.
One preventing measure is to wear surgical gloves, and to wear double gloving for easy detection of puncture in outer glove.
When using indicator gloves there becomes a dark spot were the hole is which tells you to change the glove.
At the glove cuff end it often indicate fluid of some sort by getting dark where the sleeve of the gown meets the glove cuff.
One may suspect that the fluid thrives from the hand, and if so does the fluid contains any bacteria from the hands.
In open heart surgery surgical team wear their gloves for a long period of time.
Research implicates that it occurs some recolonisation of bacteria inside the gloves.
Does recolonisation of the hand flora occur after surgical hand washing and is there a bacterial leakage at the glove cuff site?
It´s discussed that people that are in contact with hospitals carries more bacteria than others and being admitted to hospital before surgery is a risk factor.
It is also known that hospital workers are carriers of more bacteria and possibly also carriers of resistant bacteria.
At the other hand hospital workers often wash and disinfect their hands.
Are there differences in bacterial recolonization of hand flora between hospital staff at an operating department than people in average society who have little or no contact with hospitals?
研究の種類
介入
入学 (実際)
28
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究場所
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Örebro、スウェーデン、701 85
- Örbro university hospital
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参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
18年~65年 (大人、高齢者)
健康ボランティアの受け入れ
いいえ
受講資格のある性別
全て
説明
Inclusion Criteria:
- Operating nurse at the department and non-hospital persons
Exclusion Criteria:
- Participated previously in present study
- Use of gloves with antimicrobial effect
- Patient with a known infection
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか?
デザインの詳細
- 主な目的:ふるい分け
- 割り当て:非ランダム化
- 介入モデル:並列代入
- マスキング:なし(オープンラベル)
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
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実験的:OR nurse group
OR nurses (14) who agreed to participate were asked to perform a surgical hand disinfection accordingly to clinic routine.
When hands were dry cultures were first obtained at 3 sites, using a moist with saline nylon flocked swab (Copan ESwab, Italia SpA).
After hand disinfection; 1) in right hand palm, 2) between index finger and middle finger, 3) nail/cuticle of index finger.
When surgery were completed and before disposal of gloves and gown the fourth culture were taken where the glove cuff meets the gown sleeve, under and above, the inner glove of all OR nurses.When gloves were removed cultures were taken again at three sites on the hand, approximately 2-3 hours.
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Bacterial recolonization
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実験的:Non-hospital group
Non-hospital volunteers who agreed to participate were asked to perform a surgical hand disinfection accordingly to clinic routine.
When hands were dry cultures were first obtained at 3 sites, using a moist with saline nylon flocked swab (Copan ESwab, Italia SpA).
After hand disinfection; 1) in right hand palm, 2) between index finger and middle finger, 3) nail/cuticle of index finger.
This group whore gowns and gloves for approximately 2-3 hours but not kept sterile.
The Culture at the glove cuff were left out.
When gloves were removed cultures were taken again at three sites on the hand.
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Bacterial recolonization
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この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Leakage from gloves at the glove cuff site as bacterial growth cfu/mL
時間枠:3 to 4 hours
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Cultures taken after hand wash and after wearing surgical gloves for about 3 hours
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3 to 4 hours
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Differences between hand flora and its recolonisation, between hospital staff and non-hospital persons showed as bacterial growth, cfu/mL.
時間枠:2-3 hours
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Cultures taken after hand wash and after wearing surgical gloves for about 3 hours
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2-3 hours
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協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
捜査官
- 主任研究者:Camilla Wistrand, phd student、Örebro University, Sweden
出版物と役立つリンク
研究に関する情報を入力する責任者は、自発的にこれらの出版物を提供します。これらは、研究に関連するあらゆるものに関するものである可能性があります。
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始
2014年2月1日
一次修了 (実際)
2015年5月1日
研究の完了 (実際)
2015年5月1日
試験登録日
最初に提出
2015年1月21日
QC基準を満たした最初の提出物
2015年2月9日
最初の投稿 (見積もり)
2015年2月10日
学習記録の更新
投稿された最後の更新 (実際)
2017年4月4日
QC基準を満たした最後の更新が送信されました
2017年4月3日
最終確認日
2017年4月1日
詳しくは
本研究に関する用語
その他の研究ID番号
- glovecuff2014
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