Corellation of Mutations, TILs and Age in Breast Cancer
2019年7月25日 更新者:Manto Nikolaidi、Hellenic Cooperative Oncology Group
Tumor Mutational Patterns and Infiltrating Lymphocyte Density in Young and Old Patients With Breast Cancer
Age may pertain to different tumor genotype characteristics which may interfere with treatment efficacy and prognosis.
The investigators investigated the distribution and prognostic effect of mutations (mut) and tumor infiltrating lymphocyte (TILs) in young and elderly early breast cancer patients (pts).
調査の概要
研究の種類
観察的
入学 (実際)
345
参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
18年歳以上 (大人、高齢者)
健康ボランティアの受け入れ
いいえ
受講資格のある性別
女性
サンプリング方法
確率サンプル
調査対象母集団
women with early breast cancer <35 years old or >65 years old
説明
Inclusion Criteria:
- women with early breast cancer <35 years old or >65 years old
Exclusion Criteria:
- NA
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか?
デザインの詳細
コホートと介入
グループ/コホート |
介入・治療 |
---|---|
women <35 with early breast cancer
|
|
women>65 years old with early breast cancer
|
この研究は何を測定していますか?
主要な結果の測定
結果測定 |
時間枠 |
---|---|
Assessment of the prevalence of gene mutations in women <=35 years old with early breast cancer.
時間枠:Up to 13 years
|
Up to 13 years
|
Assessment of the prevalence of gene mutations in women >65years old with early breast cancer.
時間枠:Up to 13 years
|
Up to 13 years
|
Evaluation of Tumor Infiltrating Lymphocytes (TILs) density using descriptive statistics in women <=35 years old with early breast cancer.
時間枠:Up to 13 years
|
Up to 13 years
|
Evaluation of Tumor Infiltrating Lymphocytes (TILs) density using descriptive statistics in women >65 years old with early breast cancer.
時間枠:Up to 13 years
|
Up to 13 years
|
Evaluation of the prognostic effect of gene mutations and Tumor Infiltrating Lymphocytes with respect to Overall Survival in women <=35 years old with early breast cancer
時間枠:Up to 13 years
|
Up to 13 years
|
Evaluation of the prognostic effect of gene mutations and Tumor Infiltrating Lymphocytes with respect to Overall Survival in women >65 years old with early breast cancer.
時間枠:Up to 13 years
|
Up to 13 years
|
協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
捜査官
- 主任研究者:Adamantia Nikolaidi, MD、Oncology Department, MITERA Hospital
出版物と役立つリンク
研究に関する情報を入力する責任者は、自発的にこれらの出版物を提供します。これらは、研究に関連するあらゆるものに関するものである可能性があります。
一般刊行物
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研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (実際)
1997年9月3日
一次修了 (実際)
2010年10月1日
研究の完了 (実際)
2010年10月1日
試験登録日
最初に提出
2019年7月16日
QC基準を満たした最初の提出物
2019年7月25日
最初の投稿 (実際)
2019年7月26日
学習記録の更新
投稿された最後の更新 (実際)
2019年7月26日
QC基準を満たした最後の更新が送信されました
2019年7月25日
最終確認日
2019年7月1日
詳しくは
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。
乳がんの臨床試験
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Tianjin Medical University Cancer Institute and...Guangxi Medical University; Sun Yat-sen University; Chinese PLA General Hospital; The First Affiliated... と他の協力者完了
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