ザンビアにおける総合的な学校保健プログラムの評価

実験的：学校保健プログラム (SHP)

SHP は、Healthy Learners (HL) が教育省 (MOE) と協力して開発したもので、学校保健活動に関する WHO のガイドラインに従っています。 HL は、学校内の基本的な衛生設備のアップグレードと専用の「保健室」の建設を支援しています。保健衛生教育を実施し、学校内で駆虫とビタミン A 補給を調整し、臨床意思決定支援システム (CDSS) を使用して学校の保健室で病気の学習者を評価し、治療を行う学校保健員 (SHW) となるよう選ばれた教師を訓練します。学校に問い合わせるか、地元の保健センターに問い合わせてください。 保健センターでは、SHW から紹介された子供たちを優先的に医療従事者が施設到着後 30 分以内に診察します。 学校はまた、生徒ネットワーク (「バディ」システム) を作成し、学習者がお互いの欠席を監視し、SHW と調整し、SHW が家庭のフォローアップを行うことができます。

他の：総合的な学校保健プログラム

以下からなる併用介入:

• 衛生設備を改善し、校内に「保健室」を建設
• 保健教師のトレーニング: 健康学習者によって学校ごとに 5 ～ 10 人の教師が採用され、学校保健員 (SHW) になるために 2 週間のトレーニングを受けます。
• SHW は：（1）健康と良好な衛生環境に関する教育を実施します。（2）地元の診療所と連携して予防ケア（例:予防ケア）を提供します。 学校での駆虫とビタミンAの補給）。 (3) タブレットベースの臨床意思決定支援システム (CDSS) を使用して、保健室で病気の生徒を評価します。 (4) 何らかの症状（マラリア、下痢、住血吸虫症、肺炎、結膜炎）の場合は保健室で病気の生徒を治療するか、(5) 治療のために保健施設に紹介します。 (6) 学習者の欠席を監視する
• 紹介: SHW から紹介された学習者には、SHW から紹介フォームが渡されます。このフォームには、症状に関する情報と、CDSS が提案する診断が含まれています。 学習者は地元の診療所で優先的に受け入れられます。

他の名前：

• SHP

他の：駆虫とビタミン A サプリメントの配達

学校は、年に 2 回、学習者に駆虫薬とビタミン A サプリメントを配布するという政府の政策を実施しています。 Healthy Learners からの追加サポートにより、信頼性の高い配信が保証されます。

他の名前：

• 駆虫

アクティブコンパレータ：駆虫とビタミンAの補給

健全な学習者は、予防単独の効果と完全な SHP の効果を比較できるように、SHP 部門と同じ期間に年に 2 回、全国的な駆虫プログラムを確実に実施するよう努めます。

他の：駆虫とビタミン A サプリメントの配達

学校は、年に 2 回、学習者に駆虫薬とビタミン A サプリメントを配布するという政府の政策を実施しています。 Healthy Learners からの追加サポートにより、信頼性の高い配信が保証されます。

他の名前：

• 駆虫

介入なし：現状

学校は、試験が終了するまで、2006 年の学校保健・栄養政策に定められているように、政府が計画・組織する通常の活動以外は何の介入もせず、通常通り運営されることになっている。

Any healthcare utilisation

The proportion of learners who sought formal care (any government health centre or hospital, or the school health room). Equals one if reported at least once during the health diary observation period.

Proportion of serious illness episodes where child sought healthcare

The investigators will calculate this as the proportion of "serious" illness episodes for which a child seeks care, at the child level. In other words, the number of serious illness episodes with care divided by the total number of serious illness episodes, for all children with at least one serious illness episode.

A serious illness episode is one during which a child's ill-health symptoms are severe enough to require medical care, either immediately or the next day. This classification is based on WHO tools (c-IMCI and IMAI): Care is needed when (i) a child experiences any red-flag symptom (e.g. difficulty breathing, convulsions); (ii) has symptoms suggestive of certain conditions (e.g. measles, malaria); (iii) has experienced mild symptoms for a long time (coughing for 14 days, etc).

During an illness episode, a child will be considered to seek medical care if they visit (i) the health room (treatment arm) or (ii) a government clinic or hospital (any arm).

Panel-based attendance rate

The program's effect on school attendance is assessed using data collected through repeated, unannounced spot checks at each school. The primary attendance measure will be based on the sample of children enrolled in the study at baseline and confirmed to still be enrolled in their original school at the time of the visit. In this sample, the attendance rate, measured at each attendance spot check, will be the proportion of those children confirmed present in class on the day of the visit.

Register-based (cross-sectional) attendance

Additional measure of attendance, focusing on students in grades 1, 3, 5, and 7 at the time of the spot check. This register-based measure is defined as the proportion of children on the register who are present on the day of the spot check and confirmed by school staff as enrolled in the selected class on the visit day.

Malaria prevalence (proportion of children testing positive for malaria)

Testing for the presence of P. falciparum, non-falciparum species, or a mixed infection. The tests are performed using a rapid diagnostic test (RDT) on the sample of children taking part in the health diaries (testing will occur at the end of the period).

Proportion of children with moderate or severe anaemia

Haemoglobin concentration measured using a HemoCue photometer in the sample of children taking part in the health diaries (testing will occur at the end of the period). Anemia severity categories will be based on the WHO classification which depends on the age and sex of the child. Haemoglobin is first adjusted for elevation using the WHO (2024) continuous adjustment, defined in g/L as 0.0056384 times elevation in metres plus 0.0000003 times elevation squared, evaluated at each school's recorded GPS elevation and subtracted from the measured value. Moderate-to-severe anaemia is considered when adjusted haemoglobin is below 11.0 g/dL, a threshold common to all age bands represented in the sample.

Proportion of children with diarrhoea

Incidence of diarrhoea - carer report of the child experiencing three or more loose or watery stools.

Haematuria prevalence

An indicator for incidence of haematuria (blood in urine) reported by the caregiver.

Share of diary days with any reported symptom

The share of days on which the child was reported to have any symptom, over the eight week symptom diary recording period (0 days if no symptoms recorded).

Proportion of completed health-diary days on which the child reported one or more symptoms. Computed per child as (diary days with ≥1 reported symptom) ÷ (completed diary days). Defined for all children in the diary sub-sample; no conditioning on illness status.

Duration of illness episodes - all episodes

Mean number of consecutive symptom-days per illness episode, among episodes in children who reported illness during the diary window. Estimated from a discrete-time hazard model for symptom resolution: episodes still ongoing at the end of the observation window contribute their observed (censored) days rather than being dropped; episodes already symptomatic on the first diary day are excluded (start date unobservable / left-truncated). Reported as a restricted mean over the eight-week observation window.

Duration of illness episodes - serious episodes

As for the all-episodes duration outcome, restricted to episodes classified as serious.

A serious illness episode is one during which a child's ill-health symptoms are severe enough to require medical care, either immediately or the next day. This classification is based on WHO tools (c-IMCI and IMAI): Care is needed when (i) a child experiences any red-flag symptom (e.g. difficulty breathing, convulsions); (ii) has symptoms suggestive of certain conditions (e.g. measles, malaria); (iii) has experienced mild symptoms for a long time (coughing for 14 days, etc).

Mean consecutive symptom-days per serious episode, estimated from the same discrete-time hazard model, with ongoing episodes contributing observed (censored) days and day-1 episodes excluded as left-truncated. Reported as a restricted mean over the eight-week window.

Menstrual health practices

Share of responses indicating good menstrual management across the practices items. Item set is the final 5 items pilot-retained from a pre-specified pool adapted from the same validated instruments. Computed per respondent as (good-management responses) / (items answered), averaged across girls who have reached menarche in the sub-sample. Higher values indicate better practices.

Menstrual health stigma index

First principal component of a PCA over the menstrual health stigma items (final 4 items pilot-retained from a pre-specified pool adapted from the same validated instruments; construction rule fixed prior to piloting). Loadings estimated on the pooled sample; scores standardised to the control-group mean and standard deviation. Oriented so that higher values indicate lesser stigma; a beneficial programme effect corresponds to a reduction. Constructed for girls grade 5 or above who have heard of menstruation.

Learning - Literacy

Item-response-theory (IRT) ability score in literacy, estimated over per-item responses from the grade-banded exam blocks (lower-, middle-, and upper-grade versions) placed on a common within-domain scale via shared anchor items. Standardised to the control-group mean and standard deviation. Higher values indicate greater literacy ability.

Learning - Numeracy

IRT ability score in numeracy, estimated over per-item responses from the grade-banded exam blocks (lower-, middle-, upper-grade versions) linked to a common within-domain scale via shared anchor items. Standardised to the control-group mean and SD. Higher values indicate greater numeracy ability.

Learning - Science and Health

IRT ability score in science and health knowledge, estimated over per-item responses from the grade-banded exam blocks (lower-, middle-, upper-grade versions) linked to a common within-domain scale via shared anchor items. Standardised to the control-group mean and SD. Higher values indicate greater ability.

Learning - overall

Composite learning score, defined as the mean of the three control-standardised domain scores (literacy, numeracy, science), each an IRT ability score placed on a common within-domain scale across grade bands via anchor items and standardised to the control-group mean and SD. Domains enter with equal weight. Higher values indicate greater overall learning ability.

Students' working memory and attention

Students' working memory and attention is measured using the Digit Span task, a widely used short-term memory and working memory assessment. Enumerators orally present a sequence of digits at a rate of one per second, and students are asked to repeat the digits in the same order (Digit Span Forward) and then in reverse order (Digit Span Backward). The task measures students' auditory attention, concentration, and working memory capacity, which are foundational components of general cognitive functioning and predictive of academic achievement. Scores are recorded as the total number of correct sequences reproduced, following standard administration and scoring procedures.

Combined measure of attendance and retention

Proportion of children confirmed present in class on the day of the visit, out of the total number of children enrolled at the school at baseline and still alive. This measure effectively treats children who may have transferred to another study school as 'absent', dropped out, or temporarily relocated.

Attendance rate including learners transfered to other study schools

Proportion of children confirmed present in class on the day of the visit either in their original school or in another school to which they have transferred if that school is one of the study schools, out of the total number of children enrolled at baseline and still alive. Analysis will follow Intention-to-Treat principle, treating participants as assigned to their original treatment arm, even if they moved to a different study arm school.

Illness- or menstruation-related absence

From the diary's daily records, caregivers flag whether the child attended school each day and records the reason for each absent day. The reasons are: illness (1), was menstruating (2), farming (3), school closure or school event (4), bad weather (5), religious reasons (6), market day (7), public holiday (8), fishing (9), mining (10), working with parents (11), no uniform/shoes/books (12), and other (-97). A day missed is considered caused by an illness or menstruation-related absence when the reason is (1) or (2). The sample is restricted to school days by dropping weekends and public holidays. This measure is the share of the child's school days in the diary window lost to health-related absence: health-related absence days divided by total school days observed.

Menstrual health knowledge

Share of correct responses across three menstrual health knowledge items. The item set is the final items retained after in-country piloting for comprehension and relevance, from a pre-specified pool adapted from validated instruments. Computed per respondent as (correct responses) / (items answered), averaged within the relevant sub-sample: girls grade 5 or above who have heard of menstruation. Higher values indicate greater knowledge.

Boys' menstrual health knowledge

Menstrual health knowledge index (share of correct responses), constructed identically to the girls' secondary-outcome knowledge - same item set and same (correct responses) / (items answered) construction - on the sample of boys who have heard of menstruation. Higher values indicate greater knowledge. Parallels the girls' secondary outcome to assess whether the programme shifts boys' menstrual knowledge.

Boys' menstrual health stigma

Menstrual health stigma index, constructed identically to the girls' secondary-outcome stigma index - first principal component of a PCA over the same stigma items - on the sample of boys who have heard of menstruation. Standardised to the boys' control-group mean and standard deviation; oriented so that higher values indicate lesser stigma, consistent with the girls' index.

Parallels the girls' secondary outcome to assess whether the programme shifts boys' menstrual stigma.

School environment and belonging

Measured using a short school belonging and climate scale drawn from the Young Lives study, designed to capture children's subjective experiences of school in a simple, age-appropriate way. The tool focuses on core dimensions of belonging-enjoyment, perceived care from teachers and peers, safety, respect, and mutual support-using a consistent three-point response scale ("No, almost never", "Sometimes", "Yes, almost always"). Its brevity makes it suitable for large surveys with primary-school children while still capturing meaningful variation in how supported and included students feel in their school environment. To analyse responses, investigators will construct a simple index using principal component analysis, normalising on the control group for ease of interpretation.

Children's emotional well-being at school

Using the child well-being at school scale developed by the Young Lives study to capture children's emotional experiences while at school in a simple and age-appropriate way. The tool focuses on both positive and negative affective states-see appendix-and uses a consistent three-point response scale ("No, almost never", "Sometimes", "Yes, almost always"). Its simplicity makes it suitable for administration to primary school children. To analyse responses, investigators will construct a simple index using principal component analysis, normalising on the control group for ease of interpretation.

Learner-reported teacher engagement and conduct

A PCA index z-scored on the control group from the learner survey, combining a conduct checklist (teacher late, absent, or on their phone) with a 5-point Likert engagement battery (teacher cares, makes lessons interesting, offers extra help, motivates), oriented so a higher score is better conduct and engagement

Any Bullying

Indicator equal to 1 if child responds yes to any bullying item, from a five item yes/no checklist of acts experienced in the last week attended (mean names, threats, physical harm, exclusion, lies).

Bullying count

Count of acts of bullying, when child responds yes to any bullying item, from a five item yes/no checklist of acts experienced in the last week attended (mean names, threats, physical harm, exclusion, lies).

Corporal punishment

From a parallel yes/no checklist of acts a teacher used on the child in the past month, spanning verbal (shouting) and escalating physical acts. The primary measure is an indicator for any act and the secondary measures are the count of distinct acts and a physical-punishment indicator restricted to the acts involving physical contact.

Corporal punishment acceptance norms

Acceptance of corporal punishment, elicited via a teacher discipline vignette (respondents hear a scenario and rate the depicted teacher's reaction). Standardised-mean acceptance-norms index over four items: (i) own acceptability of the reaction; (ii) injunctive social norm - number of five colleagues expected to find it acceptable (0-5); (iii) descriptive social norm - number of five colleagues expected to react likewise (0-5); (iv) own behavioural attitude - self-rated likelihood of acting the same way. Each item is oriented so that higher indicates greater acceptance and standardised to the control-group mean and SD before averaging (standardisation places the differing item scales on a common metric). Higher index values indicate greater acceptance of corporal punishment.

Teacher job satisfaction

Teacher-reported job satisfaction, summarised across the eight satisfaction items (teacher satisfaction 1-8) as standardised-mean index. Higher values indicate greater satisfaction. Teacher-level.

Teacher burnout

Emotional-exhaustion subscale of the Maslach Burnout Inventory, the primary burnout indicator, summarised as subscale mean. Higher values indicate greater exhaustion.

Teacher turnover intention

Indicator = 1 if the teacher reports intending to leave teaching at the point of the survey. All endline-surveyed teachers. Higher = greater intent to leave.

Realised teacher turnover

Indicator = 1 if a teacher randomly sampled at baseline is no longer at their original school at endline (whether they left teaching or moved schools), from tracking of the baseline-sampled cohort rather than the endline survey. Population differs from the survey-based teacher outcomes; measures change over the baseline-to-endline interval. Time Frame: Unit: proportion.

Teacher locus of control

Locus-of-control index over four items:

1. "There is little I can do to help a student's learning."
2. "Pupils come unprepared from previous grades."
3. "Parents do not have the necessary education to help their child be more successful at school."
4. "If parents would do more for their children, I could do more." where respondents answer "agree" or "disagree". Summarised as standardised-mean index, oriented so that higher values indicate more locus of control.

Teacher time use - health-related duties

Self-reported hours in a typical day spent on health-related programmes in the school, from the teacher time-use module (recall over four mutually exclusive categories: teaching/instructing; planning and grading; health-related programmes; other school responsibilities). Primary time-use quantity; the mechanism-relevant category for a school-health intervention.

Teacher time use - teaching/instruction

Self-reported hours in a typical day spent teaching/instructing, from the teacher time-use module (recall over four mutually exclusive categories: teaching/instructing; planning and grading; health-related programmes; other school responsibilities). Reported alongside health-duty time to capture reallocation away from core instruction.

Anthropometry - stunting prevalence

Prevalence of stunting (chronic undernutrition) among children measured at endline. A child is classified stunted if their height-for-age z-score (HAZ) is more than 2 SD below the reference median, using the WHO Growth Reference for school-aged children and adolescents (de Onis et al. 2007; ages 5-19, sex-specific), with z-scores computed from completed age in months at the date of measurement. HAZ values outside -6 to +6 are treated as biologically implausible and excluded per WHO flagging conventions; the number of excluded observations is reported.

Any anaemia

Using the same haemoglobin measurements collected during the biomarker survey (hbg result, in g/dL), investigators will construct the proportion of children suffering from any anaemia (mild, moderate or severe), using WHO thresholds: A child is classified as anaemic if adjusted haemoglobin falls below 11.5 g/dL at ages 5 to 11, below 12.0 g/dL at ages 12 to 14, below 12.0 g/dL for non-pregnant females aged 15 and above, and below 13.0 g/dL for males aged 15 and above, with age taken at the date of the biomarker round.

Malaria - untreated infection prevalence

Indicator = 1 if a child in the biomarker sample tests positive for malaria and has no treatment recorded in their diary in the past 4 weeks; 0 otherwise, including test-negative children. Defined over all children tested, so the estimate does not condition on infection status. Because this joint indicator reflects both infection prevalence and treatment coverage, it is interpreted as descriptive/mechanistic and read alongside overall infection prevalence, not as a standalone treatment-gap contrast.

Malaria - asymptomatic infection prevalence

Indicator = 1 if a child tests positive and reports no malaria-suggestive symptom (fever, headache, vomiting, lethargy) at the time of the test or in the four preceding days; 0 otherwise, including negatives. Over all children tested; no conditioning on infection status. Descriptive/mechanistic; read alongside overall prevalence.

Parental health knowledge

Share of correct answers on a health-knowledge battery (HN01, HN04, HHK1, HHK2, DS10, HN05) covering nutrition, hygiene, and specific child illnesses. Responses will be scored as correct or incorrect, with "don't know" treated as incorrect, and summed into an additive index.

Parental relative trust in the school health room (vs government clinic)

Relative expected provider quality for the school health room versus the government clinic, from a paired quality-expectation vignette: respondents estimate, for the same 10 hypothetical febrile children, how many would receive a correct diagnosis and how many a full supply of correct treatment at each provider (0-10 each). Relative-trust index = the school-health-room minus government-clinic expectation, averaged across the diagnosis and treatment items (equivalently, the mean of the two paired differences). Positive values indicate greater expected quality at the school health room.

Willingness to pay for school health programme

From a takeit-or-leave-it elicitation in which each guardian is offered a randomly assigned annual fee for the school health room [10, 20, 30, 40 or 50 Kwacha - 30 is the real marginal cost of the programme] and states whether they would pay it. For the control group, the same elicitation takes place but the programme description is hypothetical. The willingness to pay measure is the indicator for accepting the offered price.

Anthropometry - thinness prevalence

Prevalence of thinness (acute undernutrition; the WHO term for this age group) among children measured at endline. A child is classified thin if their BMI-for-age z-score (BAZ) is more than 2 SD below the reference median, using the same WHO reference. BMI-for-age is used rather than weight-for-age, which is confounded by stunting; BMI-for-age standardises weight against the child's own height. BAZ values outside -5 to +5 are excluded as biologically implausible per WHO flagging; the number excluded is reported.