Effect of Hot Spring Therapy on Autonomic Nervous System and Exercise Performance During Altitude Training
2026年6月23日 更新者：Ziyue Ou、Macao Polytechnic University
A Randomized Controlled Trial to Investigate the Effects of Balneotherapy on Cardiac Autonomic Regulation and Exercise Performance in Healthy Adolescents Undergoing Real 1600-meter Altitude Training and Athlete Training.
This randomized controlled trial aims to investigate the effects of balneotherapy (hot spring bathing) on cardiac autonomic nervous system function and exercise performance in healthy athletes undergoing high-altitude training.
Participants will be randomly assigned to the intervention group (receiving hot spring baths three times per week (38°C, 20 minutes) combined with high-altitude training), the control group (receiving routine recovery protocols combined with high-altitude training), or the hot water immersion group (receiving hot water baths three times per week (38°C, 20 minutes) combined with high-altitude training).
Primary outcome measures include heart rate variability (HRV) indices and exercise performance indicators.
Secondary outcomes include blood lactate, peripheral oxygen saturation (SpO2), and subjective fatigue.
These findings may provide evidence for non-pharmacological interventions to enhance high-altitude training adaptation and exercise recovery.
調査の概要
状態
完了
研究の種類
介入
入学 (実際)
27
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究場所
-
-
-
Macao、中国
- Macao Polytechnic University
-
-
参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
- 子
健康ボランティアの受け入れ
はい
説明
Inclusion Criteria:
- Male or female aged 11-17years
- Regular endurance training (≥3 sessions/week) for ≥2 years
- No history of altitude exposure >2000m in the past 3 months
- No contraindications to hot water immersion (e.g., uncontrolled hypertension, severe cardiovascular disease, open wounds, pregnancy)
- Ability to provide written informed consent- Willingness to abstain from other recovery modalities (e.g., massage, cryotherapy, compression garments) during the study period
Exclusion Criteria:
- History of cardiovascular, respiratory, renal, or endocrine disorders
- Current use of medications affecting autonomic function (e.g., beta-blockers, anticholinergics)- History of syncope or heat intolerance
- Acute musculoskeletal injury within the past 6 months- Regular use of sauna, hot tub, or spa within the past month
- Pregnancy or breastfeeding (for female participants)- Shift work or trans-meridian travel within 2 weeks prior to baseline assessment
- Alcohol consumption >14 units/week or smoking
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：処理
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：独身
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
アクティブコンパレータ：Natural Recovery Group
Control group participants will undergo the same altitude training protocol (altitude 1600 meters) for 4 weeks.
After each training session, participants will receive standard recovery procedures, including 20 minutes of passive rest in a thermoneutral environment (room temperature 24°C), supplemented with mild hydration and self-selected stretching.
No hydrothermal intervention will be provided.
|
Control group participants will undergo the same altitude training protocol (altitude 1600 meters) for 4 weeks.
After each training session, participants will receive standard recovery procedures, including 20 minutes of passive rest in a thermoneutral environment (room temperature 24°C), supplemented with mild hydration and self-selected stretching.
No hydrothermal intervention will be provided.
他の名前：
|
|
アクティブコンパレータ：Hot water immersion group
The hot water immersion group will undergo a 4-week altitude training at 1600 meters above sea level.
Subjects will receive a 20-minute hot water immersion (daily tap water, 38°C±1°C) in a standardized indoor hot spring facility.
The immersion protocol involves soaking the body below the chest for 20 minutes, followed by a 10-minute rest before leaving the facility.
Three times per week.
|
The hot water immersion group will undergo a 4-week altitude training at 1600 meters above sea level.
Subjects will receive a 20-minute hot water immersion (daily tap water, 38°C±1°C) in a standardized indoor hot spring facility.
The immersion protocol involves soaking the body below the chest for 20 minutes, followed by a 10-minute rest before leaving the facility.
Three times per week.
他の名前：
|
|
実験的：Hot Spring Immersion Group
The hot spring immersion group will undergo a 4-week high-altitude training at an altitude of 1600 meters.
Subjects will receive a 20-minute hot spring therapy (natural hot spring water, 38°C ± 1°C) in a standardized indoor hot spring facility.
The immersion protocol involves soaking the body below the chest for 20 minutes, followed by a 10-minute rest before leaving the facility.
Three times per week.
|
The hot spring immersion group will undergo a 4-week high-altitude training at an altitude of 1600 meters.
Subjects will receive a 20-minute hot spring therapy (natural hot spring water, 38°C ± 1°C) in a standardized indoor hot spring facility.
The immersion protocol involves soaking the body below the chest for 20 minutes, followed by a 10-minute rest before leaving the facility.
Three times per week.
他の名前：
|
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Heart Rate Variability (HRV) - RMSSD
時間枠：Baselines were measured at the formal start of the experiment, at night during the 2nd, 3rd, and 4th weeks (post-intervention) after ascending the plateau, and post-tests were conducted one week after descending the plateau.
|
Root mean square of successive differences (RMSSD) between normal heartbeats, measured from a 5-minute seated ECG recording in a quiet, temperature-controlled (22-24°C) room after 15 minutes of rest.
A higher RMSSD value indicates stronger parasympathetic activity.
Unit: milliseconds (ms).
Baseline, Week 2, Week 3 (post-intervention).
|
Baselines were measured at the formal start of the experiment, at night during the 2nd, 3rd, and 4th weeks (post-intervention) after ascending the plateau, and post-tests were conducted one week after descending the plateau.
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
HRV - SDNN
時間枠：Baselines were measured at the formal start of the experiment, at night during the 2nd, 3rd, and 4th weeks (post-intervention) after ascending the plateau, and post-tests were conducted one week after descending the plateau.
|
Standard deviation of NN intervals (normal-to-normal R-R intervals), reflecting overall autonomic modulation.
Unit: milliseconds (ms).
Baseline, Week 2, Week 3, Week4, post-tests
|
Baselines were measured at the formal start of the experiment, at night during the 2nd, 3rd, and 4th weeks (post-intervention) after ascending the plateau, and post-tests were conducted one week after descending the plateau.
|
|
Peripheral Oxygen Saturation (SpO2)
時間枠：one month.
|
Resting peripheral oxygen saturation measured via fingertip pulse oximeter after 10 minutes of seated rest.
Unit: percentage (%)
|
one month.
|
|
Rating of Perceived Exertion (RPE)
時間枠：one month.
|
Borg 6-20 scale rating of perceived exertion recorded immediately after each training session.
Higher scores indicate greater subjective effort.
Unit: score (6-20).
Daily during intervention
|
one month.
|
|
Maximum oxygen uptake
時間枠：The baseline measurement was taken before the official start of the experiment, and the post-test was conducted one week after descending from the plateau.
|
Testing maximum oxygen uptake on a rowing ergometer combined with a cardiopulmonary function tester.
Protocol: Using a graded incremental protocol to test maximal oxygen uptake (VO2max).
Units: mL·kg-1 ·min-1.
Baseline, Week 5.
|
The baseline measurement was taken before the official start of the experiment, and the post-test was conducted one week after descending from the plateau.
|
|
30-second anaerobic power.
時間枠：The tests are scheduled before entering the plateau (baseline), during the 4th week of plateau training, and 1 week after leaving the plateau.
|
Perform a 30-s all-out test on a rowing ergometer.
Protocol: sprint at maximum effort to measure the 30-second average power.
Record power.
Units: watt.
Baseline, Week 4，1 week after altitude training.
|
The tests are scheduled before entering the plateau (baseline), during the 4th week of plateau training, and 1 week after leaving the plateau.
|
協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
出版物と役立つリンク
研究に関する情報を入力する責任者は、自発的にこれらの出版物を提供します。これらは、研究に関連するあらゆるものに関するものである可能性があります。
一般刊行物
- Laukkanen T, Khan H, Zaccardi F, Laukkanen JA. Association between sauna bathing and fatal cardiovascular and all-cause mortality events. JAMA Intern Med. 2015 Apr;175(4):542-8. doi: 10.1001/jamainternmed.2014.8187.
- Stanley J, Peake JM, Buchheit M. Consecutive days of cold water immersion: effects on cycling performance and heart rate variability. Eur J Appl Physiol. 2013 Feb;113(2):371-84. doi: 10.1007/s00421-012-2445-2. Epub 2012 Jul 3.
- Buchheit M, Simpson BM, Garvican-Lewis LA, Hammond K, Kley M, Schmidt WF, Aughey RJ, Soria R, Sargent C, Roach GD, Claros JC, Wachsmuth N, Gore CJ, Bourdon PC. Wellness, fatigue and physical performance acclimatisation to a 2-week soccer camp at 3600 m (ISA3600). Br J Sports Med. 2013 Dec;47 Suppl 1(Suppl 1):i100-6. doi: 10.1136/bjsports-2013-092749.
- Jdidi H, Dugue B, de Bisschop C, Dupuy O, Douzi W. The effects of cold exposure (cold water immersion, whole- and partial- body cryostimulation) on cardiovascular and cardiac autonomic control responses in healthy individuals: A systematic review, meta-analysis and meta-regression. J Therm Biol. 2024 Apr;121:103857. doi: 10.1016/j.jtherbio.2024.103857. Epub 2024 Apr 18.
- Michalsen A, Ludtke R, Buhring M, Spahn G, Langhorst J, Dobos GJ. Thermal hydrotherapy improves quality of life and hemodynamic function in patients with chronic heart failure. Am Heart J. 2003 Oct;146(4):728-33. doi: 10.1016/S0002-8703(03)00314-4.
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (実際)
2026年1月10日
一次修了 (実際)
2026年3月7日
研究の完了 (実際)
2026年3月8日
試験登録日
最初に提出
2026年5月14日
QC基準を満たした最初の提出物
2026年5月19日
最初の投稿 (実際)
2026年5月27日
学習記録の更新
投稿された最後の更新 (実際)
2026年6月26日
QC基準を満たした最後の更新が送信されました
2026年6月23日
最終確認日
2026年1月1日
詳しくは
本研究に関する用語
その他の研究ID番号
- 202502AS100005
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
未定
IPD プランの説明
The current research project has not yet been completed, and the data have not been publicly released.
After publication, sharing will be decided on a case-by-case basis.
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
いいえ
米国FDA規制機器製品の研究
いいえ
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。