Effects of Tool Handling on Language Processing
2026年7月15日 更新者：Aline de Souza Pagnussat、Federal University of Health Science of Porto Alegre
Analysis of the Effect of a Tool-Handling Intervention in a Specific Context on the Linguistic Processing of Healthy Young Adults
This randomized controlled trial aims to investigate the effects of a context-specific tool-handling intervention on linguistic processing in healthy young adults. Participants will be allocated into three groups: a dexterous tool-use training group, a dexterous manual training group without tools, and a Control group.
The dexterous tool-use training group will perform a task-oriented activity involving the use of tweezers to place colored beads into a mandala within a specific functional context. The intervention requires sequential motor planning, force control, precision, and goal-directed tool use. The dexterous manual training group without tools will perform a similar bead-placement activity without tool use, involving direct hand manipulation and lower task complexity. Both intervention groups will participate in synchronous online sessions via Google Meet for 20 minutes per day, five times per week, over a two-week period.
The Control group will not receive any structured intervention and will instead be instructed to perform one activity of daily living using the non-dominant upper limb once per day during the two-week period.
Linguistic processing will be assessed through a sentence judgment task involving sentences with and without semantic violations, in which participants will classify the sentences as correct or incorrect while electroencephalographic activity (EEG) is recorded. Additionally, sleep quality and manual dexterity will also be evaluated.
The findings of this study may contribute to understanding the relationship between tool-related motor training and linguistic processing, particularly the interaction between motor and language systems in healthy young adults. Additionally, the study may provide evidence regarding neurophysiological changes associated with context-specific motor interventions.
調査の概要
状態
まだ募集していません
条件
研究の種類
介入
入学 (推定)
60
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究連絡先
- 名前：Aline Pagnussat, PhD
- 電話番号：+55 51 3303-8912
- メール：alinesp@ufcspa.edu.br
研究場所
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Rio Grande do Sul
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Porto Alegre、Rio Grande do Sul、ブラジル、90050170
- UFCSPA
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コンタクト：
- Thainara Cruz da Rosa, MsC
- 電話番号：+55 51 991591680
- メール：thainaracruzr@gmail.com
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-
参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
- 大人
健康ボランティアの受け入れ
はい
説明
Inclusion Criteria:
- Healthy young adults aged between 19 and 24 years;
- Right-handed individuals.
Exclusion Criteria:
- Previous diagnosis of neurological and/or psychiatric disorders;
- History of traumatic brain injury;
- Use of psychoactive substances or medications that may affect cognitive functioning;
- Pregnancy or suspected pregnancy.
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：処理
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：ダブル
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
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アクティブコンパレータ：コントロール
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Participants allocated to the control group will not receive structured training.
They will be instructed to perform one activity of daily living using the non-dominant upper limb once per day during the two-week study period.
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実験的：Dexterous tool-use training
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The intervention will be supervised by a researcher through assynchronous way.
Participants will perform a task-oriented activity involving the use of tweezers to place colored beads into a mandala within a functional and goal-directed context.
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アクティブコンパレータ：Dexterous manual training group without tools
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The intervention will be supervised by a researcher through assynchronous way.
Participants will perform a bead-placement activity directly with their hands, without the use of tools.
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Assessment of Synthatic Processing Performance - Reaction time
時間枠：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
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Linguistic processing will be evaluated through a computerized sentence judgment task composed of 60 sentences containing grammatical agreement violations and control sentences.
Reaction time will be measured as the time elapsed between the presentation of each sentence and the participant's button press indicating whether the sentence is grammatically correct or incorrect.
Mean reaction time across trials will be reported in milliseconds (ms).
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Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
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Assessment of Synthatic Processing Performance - Accuracy
時間枠：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
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Linguistic processing will be evaluated through a computerized sentence judgment task composed of 60 sentences containing grammatical agreement violations and control sentences.
Accuracy will be assessed as the absolute number of correct responses.
The absolute number of incorrect responses (errors) will also be recorded.
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Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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N200 Event-Related Potential Mean Amplitude
時間枠：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations.
The mean amplitude of the N200 component will be measured within the predefined time window and electrodes of interest.
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Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
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P300 Event-Related Potential Mean Amplitude
時間枠：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations.
The mean amplitude of the P300 component will be measured within the predefined time window and electrodes of interest.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
N200 Event-Related Potential Peak Latency
時間枠：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations.
The peak latency of the N200 component will be measured within the predefined time window and electrodes of interest.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
P300 Event-Related Potential Peak latency
時間枠：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations.
The peaky latency of the P300 component will be measured within the predefined time window and electrodes of interest.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
Assessment of Syntactic Production - Hierarchical Embedding in Spontaneous Discourse
時間枠：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Syntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB).
Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform.
Hierarchical embedding will be quantified as an index of syntactic complexity.
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Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
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Assessment of Syntactic Production - Clauses per Sentence in Spontaneous Discourse
時間枠：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Syntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB).
Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform.
Clauses per sentence will be calculated as a measure of syntactic complexity.
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Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
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Assessment of Syntactic Production - Left-Branching Load (Frazier Index) in Spontaneous Discourse
時間枠：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
SSyntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB).
Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform.
Left-branching load will be quantified using the Frazier Index.
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Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
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Manual dexterity
時間枠：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
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Manual dexterity, visuomotor coordination, and executive functioning will be assessed using the Grooved Pegboard Test (GPT).
Participants will insert grooved pegs into a board as quickly as possible using both dominant and non-dominant hands.
Completion time (in seconds) will be recorded for each hand.
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Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
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その他の成果指標
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Assessment of Sleep Quality
時間枠：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI).
The questionnaire evaluates subjective sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbances, use of sleep medication, and daytime dysfunction.
Total scores range from 0 to 21, with scores above 5 indicating poor sleep quality.
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Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
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協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (推定)
2026年7月31日
一次修了 (推定)
2026年12月31日
研究の完了 (推定)
2027年3月31日
試験登録日
最初に提出
2026年6月11日
QC基準を満たした最初の提出物
2026年7月15日
最初の投稿 (実際)
2026年7月22日
学習記録の更新
投稿された最後の更新 (実際)
2026年7月22日
QC基準を満たした最後の更新が送信されました
2026年7月15日
最終確認日
2026年6月1日
詳しくは
本研究に関する用語
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
いいえ
IPD プランの説明
No plan to share individual participant data (IPD).
Data will not be shared due to ethical and confidentiality considerations related to participant privacy and the terms of informed consent.
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
いいえ
米国FDA規制機器製品の研究
いいえ
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。