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Effects of Tool Handling on Language Processing

15 juli 2026 bijgewerkt door: Aline de Souza Pagnussat, Federal University of Health Science of Porto Alegre

Analysis of the Effect of a Tool-Handling Intervention in a Specific Context on the Linguistic Processing of Healthy Young Adults

This randomized controlled trial aims to investigate the effects of a context-specific tool-handling intervention on linguistic processing in healthy young adults. Participants will be allocated into three groups: a dexterous tool-use training group, a dexterous manual training group without tools, and a Control group.

The dexterous tool-use training group will perform a task-oriented activity involving the use of tweezers to place colored beads into a mandala within a specific functional context. The intervention requires sequential motor planning, force control, precision, and goal-directed tool use. The dexterous manual training group without tools will perform a similar bead-placement activity without tool use, involving direct hand manipulation and lower task complexity. Both intervention groups will participate in synchronous online sessions via Google Meet for 20 minutes per day, five times per week, over a two-week period.

The Control group will not receive any structured intervention and will instead be instructed to perform one activity of daily living using the non-dominant upper limb once per day during the two-week period.

Linguistic processing will be assessed through a sentence judgment task involving sentences with and without semantic violations, in which participants will classify the sentences as correct or incorrect while electroencephalographic activity (EEG) is recorded. Additionally, sleep quality and manual dexterity will also be evaluated.

The findings of this study may contribute to understanding the relationship between tool-related motor training and linguistic processing, particularly the interaction between motor and language systems in healthy young adults. Additionally, the study may provide evidence regarding neurophysiological changes associated with context-specific motor interventions.

Studie Overzicht

Toestand

Nog niet aan het werven

Conditie

Interventie / Behandeling

Studietype

Ingrijpend

Inschrijving (Geschat)

60

Fase

  • Niet toepasbaar

Contacten en locaties

In dit gedeelte vindt u de contactgegevens van degenen die het onderzoek uitvoeren en informatie over waar dit onderzoek wordt uitgevoerd.

Studiecontact

Studie Locaties

  • Brazilië
    • Rio Grande do Sul
      • Porto Alegre, Rio Grande do Sul, Brazilië, 90050170

Deelname Criteria

Onderzoekers zoeken naar mensen die aan een bepaalde beschrijving voldoen, de zogenaamde geschiktheidscriteria. Enkele voorbeelden van deze criteria zijn iemands algemene gezondheidstoestand of eerdere behandelingen.

Geschiktheidscriteria

Leeftijden die in aanmerking komen voor studie

  • Volwassen

Accepteert gezonde vrijwilligers

Ja

Beschrijving

Inclusion Criteria:

  • Healthy young adults aged between 19 and 24 years;
  • Right-handed individuals.

Exclusion Criteria:

  • Previous diagnosis of neurological and/or psychiatric disorders;
  • History of traumatic brain injury;
  • Use of psychoactive substances or medications that may affect cognitive functioning;
  • Pregnancy or suspected pregnancy.

Studie plan

Dit gedeelte bevat details van het studieplan, inclusief hoe de studie is opgezet en wat de studie meet.

Hoe is de studie opgezet?

Ontwerpdetails

  • Primair doel: Behandeling
  • Toewijzing: Gerandomiseerd
  • Interventioneel model: Parallelle opdracht
  • Masker: Dubbele

Wapens en interventies

Deelnemersgroep / Arm
Interventie / Behandeling
Actieve vergelijker: Controle
Gedragsmatig: Control
Participants allocated to the control group will not receive structured training. They will be instructed to perform one activity of daily living using the non-dominant upper limb once per day during the two-week study period.
Experimenteel: Dexterous tool-use training
Gedragsmatig: Dexterous tool-use training
The intervention will be supervised by a researcher through assynchronous way. Participants will perform a task-oriented activity involving the use of tweezers to place colored beads into a mandala within a functional and goal-directed context.
Actieve vergelijker: Dexterous manual training group without tools
Gedragsmatig: Dexterous manual training group without tools (Online)
The intervention will be supervised by a researcher through assynchronous way. Participants will perform a bead-placement activity directly with their hands, without the use of tools.

Wat meet het onderzoek?

Primaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Assessment of Synthatic Processing Performance - Reaction time
Tijdsspanne: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Linguistic processing will be evaluated through a computerized sentence judgment task composed of 60 sentences containing grammatical agreement violations and control sentences. Reaction time will be measured as the time elapsed between the presentation of each sentence and the participant's button press indicating whether the sentence is grammatically correct or incorrect. Mean reaction time across trials will be reported in milliseconds (ms).
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Assessment of Synthatic Processing Performance - Accuracy
Tijdsspanne: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Linguistic processing will be evaluated through a computerized sentence judgment task composed of 60 sentences containing grammatical agreement violations and control sentences. Accuracy will be assessed as the absolute number of correct responses. The absolute number of incorrect responses (errors) will also be recorded.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)

Secundaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
N200 Event-Related Potential Mean Amplitude
Tijdsspanne: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations. The mean amplitude of the N200 component will be measured within the predefined time window and electrodes of interest.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
P300 Event-Related Potential Mean Amplitude
Tijdsspanne: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations. The mean amplitude of the P300 component will be measured within the predefined time window and electrodes of interest.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
N200 Event-Related Potential Peak Latency
Tijdsspanne: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations. The peak latency of the N200 component will be measured within the predefined time window and electrodes of interest.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
P300 Event-Related Potential Peak latency
Tijdsspanne: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations. The peaky latency of the P300 component will be measured within the predefined time window and electrodes of interest.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Assessment of Syntactic Production - Hierarchical Embedding in Spontaneous Discourse
Tijdsspanne: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Syntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB). Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform. Hierarchical embedding will be quantified as an index of syntactic complexity.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Assessment of Syntactic Production - Clauses per Sentence in Spontaneous Discourse
Tijdsspanne: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Syntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB). Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform. Clauses per sentence will be calculated as a measure of syntactic complexity.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Assessment of Syntactic Production - Left-Branching Load (Frazier Index) in Spontaneous Discourse
Tijdsspanne: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
SSyntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB). Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform. Left-branching load will be quantified using the Frazier Index.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Manual dexterity
Tijdsspanne: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Manual dexterity, visuomotor coordination, and executive functioning will be assessed using the Grooved Pegboard Test (GPT). Participants will insert grooved pegs into a board as quickly as possible using both dominant and non-dominant hands. Completion time (in seconds) will be recorded for each hand.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)

Andere uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Assessment of Sleep Quality
Tijdsspanne: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluates subjective sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbances, use of sleep medication, and daytime dysfunction. Total scores range from 0 to 21, with scores above 5 indicating poor sleep quality.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)

Medewerkers en onderzoekers

Hier vindt u mensen en organisaties die betrokken zijn bij dit onderzoek.

Sponsor

Federal University of Health Science of Porto Alegre

Studie record data

Deze datums volgen de voortgang van het onderzoeksdossier en de samenvatting van de ingediende resultaten bij ClinicalTrials.gov. Studieverslagen en gerapporteerde resultaten worden beoordeeld door de National Library of Medicine (NLM) om er zeker van te zijn dat ze voldoen aan specifieke kwaliteitscontrolenormen voordat ze op de openbare website worden geplaatst.

Bestudeer belangrijke data

Studie start (Geschat)

31 juli 2026

Primaire voltooiing (Geschat)

31 december 2026

Studie voltooiing (Geschat)

31 maart 2027

Studieregistratiedata

Eerst ingediend

11 juni 2026

Eerst ingediend dat voldeed aan de QC-criteria

15 juli 2026

Eerst geplaatst (Werkelijk)

22 juli 2026

Updates van studierecords

Laatste update geplaatst (Werkelijk)

22 juli 2026

Laatste update ingediend die voldeed aan QC-criteria

15 juli 2026

Laatst geverifieerd

1 juni 2026

Meer informatie

Termen gerelateerd aan deze studie

Trefwoorden

Aanvullende relevante MeSH-voorwaarden

Andere studie-ID-nummers

  • TOOLANG

Plan Individuele Deelnemersgegevens (IPD)

Bent u van plan om gegevens van individuele deelnemers (IPD) te delen?

NEE

Beschrijving IPD-plan

No plan to share individual participant data (IPD). Data will not be shared due to ethical and confidentiality considerations related to participant privacy and the terms of informed consent.

Informatie over medicijnen en apparaten, studiedocumenten

Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel

Nee

Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct

Nee

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