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Effects of Tool Handling on Language Processing

15. juli 2026 oppdatert av: Aline de Souza Pagnussat, Federal University of Health Science of Porto Alegre

Analysis of the Effect of a Tool-Handling Intervention in a Specific Context on the Linguistic Processing of Healthy Young Adults

This randomized controlled trial aims to investigate the effects of a context-specific tool-handling intervention on linguistic processing in healthy young adults. Participants will be allocated into three groups: a dexterous tool-use training group, a dexterous manual training group without tools, and a Control group.

The dexterous tool-use training group will perform a task-oriented activity involving the use of tweezers to place colored beads into a mandala within a specific functional context. The intervention requires sequential motor planning, force control, precision, and goal-directed tool use. The dexterous manual training group without tools will perform a similar bead-placement activity without tool use, involving direct hand manipulation and lower task complexity. Both intervention groups will participate in synchronous online sessions via Google Meet for 20 minutes per day, five times per week, over a two-week period.

The Control group will not receive any structured intervention and will instead be instructed to perform one activity of daily living using the non-dominant upper limb once per day during the two-week period.

Linguistic processing will be assessed through a sentence judgment task involving sentences with and without semantic violations, in which participants will classify the sentences as correct or incorrect while electroencephalographic activity (EEG) is recorded. Additionally, sleep quality and manual dexterity will also be evaluated.

The findings of this study may contribute to understanding the relationship between tool-related motor training and linguistic processing, particularly the interaction between motor and language systems in healthy young adults. Additionally, the study may provide evidence regarding neurophysiological changes associated with context-specific motor interventions.

Studieoversikt

Status

Har ikke rekruttert ennå

Forhold

Intervensjon / Behandling

Studietype

Intervensjonell

Registrering (Antatt)

60

Fase

  • Ikke aktuelt

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiekontakt

Studiesteder

  • Brasil
    • Rio Grande do Sul
      • Porto Alegre, Rio Grande do Sul, Brasil, 90050170
        • UFCSPA
        • Ta kontakt med:

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

  • Voksen

Tar imot friske frivillige

Ja

Beskrivelse

Inclusion Criteria:

  • Healthy young adults aged between 19 and 24 years;
  • Right-handed individuals.

Exclusion Criteria:

  • Previous diagnosis of neurological and/or psychiatric disorders;
  • History of traumatic brain injury;
  • Use of psychoactive substances or medications that may affect cognitive functioning;
  • Pregnancy or suspected pregnancy.

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

  • Primært formål: Behandling
  • Tildeling: Randomisert
  • Intervensjonsmodell: Parallell tildeling
  • Masking: Dobbelt

Våpen og intervensjoner

Deltakergruppe / Arm
Intervensjon / Behandling
Aktiv komparator: Styre
Atferdsmessig: Control
Participants allocated to the control group will not receive structured training. They will be instructed to perform one activity of daily living using the non-dominant upper limb once per day during the two-week study period.
Eksperimentell: Dexterous tool-use training
Atferdsmessig: Dexterous tool-use training
The intervention will be supervised by a researcher through assynchronous way. Participants will perform a task-oriented activity involving the use of tweezers to place colored beads into a mandala within a functional and goal-directed context.
Aktiv komparator: Dexterous manual training group without tools
Atferdsmessig: Dexterous manual training group without tools (Online)
The intervention will be supervised by a researcher through assynchronous way. Participants will perform a bead-placement activity directly with their hands, without the use of tools.

Hva måler studien?

Primære resultatmål

Resultatmål
Tiltaksbeskrivelse
Tidsramme
Assessment of Synthatic Processing Performance - Reaction time
Tidsramme: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Linguistic processing will be evaluated through a computerized sentence judgment task composed of 60 sentences containing grammatical agreement violations and control sentences. Reaction time will be measured as the time elapsed between the presentation of each sentence and the participant's button press indicating whether the sentence is grammatically correct or incorrect. Mean reaction time across trials will be reported in milliseconds (ms).
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Assessment of Synthatic Processing Performance - Accuracy
Tidsramme: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Linguistic processing will be evaluated through a computerized sentence judgment task composed of 60 sentences containing grammatical agreement violations and control sentences. Accuracy will be assessed as the absolute number of correct responses. The absolute number of incorrect responses (errors) will also be recorded.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)

Sekundære resultatmål

Resultatmål
Tiltaksbeskrivelse
Tidsramme
N200 Event-Related Potential Mean Amplitude
Tidsramme: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations. The mean amplitude of the N200 component will be measured within the predefined time window and electrodes of interest.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
P300 Event-Related Potential Mean Amplitude
Tidsramme: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations. The mean amplitude of the P300 component will be measured within the predefined time window and electrodes of interest.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
N200 Event-Related Potential Peak Latency
Tidsramme: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations. The peak latency of the N200 component will be measured within the predefined time window and electrodes of interest.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
P300 Event-Related Potential Peak latency
Tidsramme: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations. The peaky latency of the P300 component will be measured within the predefined time window and electrodes of interest.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Assessment of Syntactic Production - Hierarchical Embedding in Spontaneous Discourse
Tidsramme: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Syntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB). Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform. Hierarchical embedding will be quantified as an index of syntactic complexity.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Assessment of Syntactic Production - Clauses per Sentence in Spontaneous Discourse
Tidsramme: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Syntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB). Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform. Clauses per sentence will be calculated as a measure of syntactic complexity.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Assessment of Syntactic Production - Left-Branching Load (Frazier Index) in Spontaneous Discourse
Tidsramme: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
SSyntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB). Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform. Left-branching load will be quantified using the Frazier Index.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Manual dexterity
Tidsramme: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Manual dexterity, visuomotor coordination, and executive functioning will be assessed using the Grooved Pegboard Test (GPT). Participants will insert grooved pegs into a board as quickly as possible using both dominant and non-dominant hands. Completion time (in seconds) will be recorded for each hand.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)

Andre resultatmål

Resultatmål
Tiltaksbeskrivelse
Tidsramme
Assessment of Sleep Quality
Tidsramme: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluates subjective sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbances, use of sleep medication, and daytime dysfunction. Total scores range from 0 to 21, with scores above 5 indicating poor sleep quality.
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

Federal University of Health Science of Porto Alegre

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart (Antatt)

31. juli 2026

Primær fullføring (Antatt)

31. desember 2026

Studiet fullført (Antatt)

31. mars 2027

Datoer for studieregistrering

Først innsendt

11. juni 2026

Først innsendt som oppfylte QC-kriteriene

15. juli 2026

Først lagt ut (Faktiske)

22. juli 2026

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

22. juli 2026

Siste oppdatering sendt inn som oppfylte QC-kriteriene

15. juli 2026

Sist bekreftet

1. juni 2026

Mer informasjon

Begreper knyttet til denne studien

Nøkkelord

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

  • TOOLANG

Plan for individuelle deltakerdata (IPD)

Planlegger du å dele individuelle deltakerdata (IPD)?

NEI

IPD-planbeskrivelse

No plan to share individual participant data (IPD). Data will not be shared due to ethical and confidentiality considerations related to participant privacy and the terms of informed consent.

Legemiddel- og utstyrsinformasjon, studiedokumenter

Studerer et amerikansk FDA-regulert medikamentprodukt

Nei

Studerer et amerikansk FDA-regulert enhetsprodukt

Nei

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