Effects of Tool Handling on Language Processing
2026年7月15日 更新者：Aline de Souza Pagnussat、Federal University of Health Science of Porto Alegre
Analysis of the Effect of a Tool-Handling Intervention in a Specific Context on the Linguistic Processing of Healthy Young Adults
This randomized controlled trial aims to investigate the effects of a context-specific tool-handling intervention on linguistic processing in healthy young adults. Participants will be allocated into three groups: a dexterous tool-use training group, a dexterous manual training group without tools, and a Control group.
The dexterous tool-use training group will perform a task-oriented activity involving the use of tweezers to place colored beads into a mandala within a specific functional context. The intervention requires sequential motor planning, force control, precision, and goal-directed tool use. The dexterous manual training group without tools will perform a similar bead-placement activity without tool use, involving direct hand manipulation and lower task complexity. Both intervention groups will participate in synchronous online sessions via Google Meet for 20 minutes per day, five times per week, over a two-week period.
The Control group will not receive any structured intervention and will instead be instructed to perform one activity of daily living using the non-dominant upper limb once per day during the two-week period.
Linguistic processing will be assessed through a sentence judgment task involving sentences with and without semantic violations, in which participants will classify the sentences as correct or incorrect while electroencephalographic activity (EEG) is recorded. Additionally, sleep quality and manual dexterity will also be evaluated.
The findings of this study may contribute to understanding the relationship between tool-related motor training and linguistic processing, particularly the interaction between motor and language systems in healthy young adults. Additionally, the study may provide evidence regarding neurophysiological changes associated with context-specific motor interventions.
研究概览
地位
尚未招聘
条件
研究类型
介入性
注册 (估计的)
60
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习联系方式
- 姓名：Aline Pagnussat, PhD
- 电话号码：+55 51 3303-8912
- 邮箱：alinesp@ufcspa.edu.br
学习地点
-
-
Rio Grande do Sul
-
Porto Alegre、Rio Grande do Sul、巴西、90050170
- UFCSPA
-
接触：
- Thainara Cruz da Rosa, MsC
- 电话号码：+55 51 991591680
- 邮箱：thainaracruzr@gmail.com
-
-
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 成人
接受健康志愿者
是的
描述
Inclusion Criteria:
- Healthy young adults aged between 19 and 24 years;
- Right-handed individuals.
Exclusion Criteria:
- Previous diagnosis of neurological and/or psychiatric disorders;
- History of traumatic brain injury;
- Use of psychoactive substances or medications that may affect cognitive functioning;
- Pregnancy or suspected pregnancy.
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：双倍的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
有源比较器：控制
|
Participants allocated to the control group will not receive structured training.
They will be instructed to perform one activity of daily living using the non-dominant upper limb once per day during the two-week study period.
|
|
实验性的：Dexterous tool-use training
|
The intervention will be supervised by a researcher through assynchronous way.
Participants will perform a task-oriented activity involving the use of tweezers to place colored beads into a mandala within a functional and goal-directed context.
|
|
有源比较器：Dexterous manual training group without tools
|
The intervention will be supervised by a researcher through assynchronous way.
Participants will perform a bead-placement activity directly with their hands, without the use of tools.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Assessment of Synthatic Processing Performance - Reaction time
大体时间：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Linguistic processing will be evaluated through a computerized sentence judgment task composed of 60 sentences containing grammatical agreement violations and control sentences.
Reaction time will be measured as the time elapsed between the presentation of each sentence and the participant's button press indicating whether the sentence is grammatically correct or incorrect.
Mean reaction time across trials will be reported in milliseconds (ms).
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
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Assessment of Synthatic Processing Performance - Accuracy
大体时间：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Linguistic processing will be evaluated through a computerized sentence judgment task composed of 60 sentences containing grammatical agreement violations and control sentences.
Accuracy will be assessed as the absolute number of correct responses.
The absolute number of incorrect responses (errors) will also be recorded.
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Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
N200 Event-Related Potential Mean Amplitude
大体时间：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations.
The mean amplitude of the N200 component will be measured within the predefined time window and electrodes of interest.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
P300 Event-Related Potential Mean Amplitude
大体时间：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations.
The mean amplitude of the P300 component will be measured within the predefined time window and electrodes of interest.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
N200 Event-Related Potential Peak Latency
大体时间：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations.
The peak latency of the N200 component will be measured within the predefined time window and electrodes of interest.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
P300 Event-Related Potential Peak latency
大体时间：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations.
The peaky latency of the P300 component will be measured within the predefined time window and electrodes of interest.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
Assessment of Syntactic Production - Hierarchical Embedding in Spontaneous Discourse
大体时间：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Syntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB).
Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform.
Hierarchical embedding will be quantified as an index of syntactic complexity.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
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Assessment of Syntactic Production - Clauses per Sentence in Spontaneous Discourse
大体时间：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Syntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB).
Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform.
Clauses per sentence will be calculated as a measure of syntactic complexity.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
Assessment of Syntactic Production - Left-Branching Load (Frazier Index) in Spontaneous Discourse
大体时间：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
SSyntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB).
Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform.
Left-branching load will be quantified using the Frazier Index.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
Manual dexterity
大体时间：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Manual dexterity, visuomotor coordination, and executive functioning will be assessed using the Grooved Pegboard Test (GPT).
Participants will insert grooved pegs into a board as quickly as possible using both dominant and non-dominant hands.
Completion time (in seconds) will be recorded for each hand.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
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其他结果措施
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Assessment of Sleep Quality
大体时间：Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI).
The questionnaire evaluates subjective sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbances, use of sleep medication, and daytime dysfunction.
Total scores range from 0 to 21, with scores above 5 indicating poor sleep quality.
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Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (估计的)
2026年7月31日
初级完成 (估计的)
2026年12月31日
研究完成 (估计的)
2027年3月31日
研究注册日期
首次提交
2026年6月11日
首先提交符合 QC 标准的
2026年7月15日
首次发布 (实际的)
2026年7月22日
研究记录更新
最后更新发布 (实际的)
2026年7月22日
上次提交的符合 QC 标准的更新
2026年7月15日
最后验证
2026年6月1日
更多信息
与本研究相关的术语
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
不
IPD 计划说明
No plan to share individual participant data (IPD).
Data will not be shared due to ethical and confidentiality considerations related to participant privacy and the terms of informed consent.
药物和器械信息、研究文件
研究美国 FDA 监管的药品
不
研究美国 FDA 监管的设备产品
不
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