Effects of Tool Handling on Language Processing
15 luglio 2026 aggiornato da: Aline de Souza Pagnussat, Federal University of Health Science of Porto Alegre
Analysis of the Effect of a Tool-Handling Intervention in a Specific Context on the Linguistic Processing of Healthy Young Adults
This randomized controlled trial aims to investigate the effects of a context-specific tool-handling intervention on linguistic processing in healthy young adults. Participants will be allocated into three groups: a dexterous tool-use training group, a dexterous manual training group without tools, and a Control group.
The dexterous tool-use training group will perform a task-oriented activity involving the use of tweezers to place colored beads into a mandala within a specific functional context. The intervention requires sequential motor planning, force control, precision, and goal-directed tool use. The dexterous manual training group without tools will perform a similar bead-placement activity without tool use, involving direct hand manipulation and lower task complexity. Both intervention groups will participate in synchronous online sessions via Google Meet for 20 minutes per day, five times per week, over a two-week period.
The Control group will not receive any structured intervention and will instead be instructed to perform one activity of daily living using the non-dominant upper limb once per day during the two-week period.
Linguistic processing will be assessed through a sentence judgment task involving sentences with and without semantic violations, in which participants will classify the sentences as correct or incorrect while electroencephalographic activity (EEG) is recorded. Additionally, sleep quality and manual dexterity will also be evaluated.
The findings of this study may contribute to understanding the relationship between tool-related motor training and linguistic processing, particularly the interaction between motor and language systems in healthy young adults. Additionally, the study may provide evidence regarding neurophysiological changes associated with context-specific motor interventions.
Panoramica dello studio
Stato
Non ancora reclutamento
Condizioni
Tipo di studio
Interventistico
Iscrizione (Stimato)
60
Fase
- Non applicabile
Contatti e Sedi
Questa sezione fornisce i recapiti di coloro che conducono lo studio e informazioni su dove viene condotto lo studio.
Contatto studio
- Nome: Aline Pagnussat, PhD
- Numero di telefono: +55 51 3303-8912
- Email: alinesp@ufcspa.edu.br
Luoghi di studio
-
-
Rio Grande do Sul
-
Porto Alegre, Rio Grande do Sul, Brasile, 90050170
- UFCSPA
-
Contatto:
- Thainara Cruz da Rosa, MsC
- Numero di telefono: +55 51 991591680
- Email: thainaracruzr@gmail.com
-
-
Criteri di partecipazione
I ricercatori cercano persone che corrispondano a una certa descrizione, chiamata criteri di ammissibilità. Alcuni esempi di questi criteri sono le condizioni generali di salute di una persona o trattamenti precedenti.
Criteri di ammissibilità
Età idonea allo studio
- Adulto
Accetta volontari sani
Sì
Descrizione
Inclusion Criteria:
- Healthy young adults aged between 19 and 24 years;
- Right-handed individuals.
Exclusion Criteria:
- Previous diagnosis of neurological and/or psychiatric disorders;
- History of traumatic brain injury;
- Use of psychoactive substances or medications that may affect cognitive functioning;
- Pregnancy or suspected pregnancy.
Piano di studio
Questa sezione fornisce i dettagli del piano di studio, compreso il modo in cui lo studio è progettato e ciò che lo studio sta misurando.
Come è strutturato lo studio?
Dettagli di progettazione
- Scopo principale: Trattamento
- Assegnazione: Randomizzato
- Modello interventistico: Assegnazione parallela
- Mascheramento: Doppio
Armi e interventi
Gruppo di partecipanti / Arm |
Intervento / Trattamento |
|---|---|
|
Comparatore attivo: Controllo
|
Participants allocated to the control group will not receive structured training.
They will be instructed to perform one activity of daily living using the non-dominant upper limb once per day during the two-week study period.
|
|
Sperimentale: Dexterous tool-use training
|
The intervention will be supervised by a researcher through assynchronous way.
Participants will perform a task-oriented activity involving the use of tweezers to place colored beads into a mandala within a functional and goal-directed context.
|
|
Comparatore attivo: Dexterous manual training group without tools
|
The intervention will be supervised by a researcher through assynchronous way.
Participants will perform a bead-placement activity directly with their hands, without the use of tools.
|
Cosa sta misurando lo studio?
Misure di risultato primarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
|---|---|---|
|
Assessment of Synthatic Processing Performance - Reaction time
Lasso di tempo: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Linguistic processing will be evaluated through a computerized sentence judgment task composed of 60 sentences containing grammatical agreement violations and control sentences.
Reaction time will be measured as the time elapsed between the presentation of each sentence and the participant's button press indicating whether the sentence is grammatically correct or incorrect.
Mean reaction time across trials will be reported in milliseconds (ms).
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
Assessment of Synthatic Processing Performance - Accuracy
Lasso di tempo: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Linguistic processing will be evaluated through a computerized sentence judgment task composed of 60 sentences containing grammatical agreement violations and control sentences.
Accuracy will be assessed as the absolute number of correct responses.
The absolute number of incorrect responses (errors) will also be recorded.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Misure di risultato secondarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
|---|---|---|
|
N200 Event-Related Potential Mean Amplitude
Lasso di tempo: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations.
The mean amplitude of the N200 component will be measured within the predefined time window and electrodes of interest.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
P300 Event-Related Potential Mean Amplitude
Lasso di tempo: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations.
The mean amplitude of the P300 component will be measured within the predefined time window and electrodes of interest.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
N200 Event-Related Potential Peak Latency
Lasso di tempo: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations.
The peak latency of the N200 component will be measured within the predefined time window and electrodes of interest.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
P300 Event-Related Potential Peak latency
Lasso di tempo: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Event-related potentials (ERPs) will be recorded using electroencephalography (EEG) during a computerized linguistic judgment task involving sentences with and without gender and number agreement violations.
The peaky latency of the P300 component will be measured within the predefined time window and electrodes of interest.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
Assessment of Syntactic Production - Hierarchical Embedding in Spontaneous Discourse
Lasso di tempo: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Syntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB).
Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform.
Hierarchical embedding will be quantified as an index of syntactic complexity.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
Assessment of Syntactic Production - Clauses per Sentence in Spontaneous Discourse
Lasso di tempo: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Syntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB).
Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform.
Clauses per sentence will be calculated as a measure of syntactic complexity.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
Assessment of Syntactic Production - Left-Branching Load (Frazier Index) in Spontaneous Discourse
Lasso di tempo: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
SSyntactic production will be assessed through a spontaneous discourse task using the "Picnic Scene" from the Western Aphasia Battery (WAB).
Speech samples will be audio-recorded, transcribed, and analyzed using the NILC-Metrix platform.
Left-branching load will be quantified using the Frazier Index.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
|
Manual dexterity
Lasso di tempo: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Manual dexterity, visuomotor coordination, and executive functioning will be assessed using the Grooved Pegboard Test (GPT).
Participants will insert grooved pegs into a board as quickly as possible using both dominant and non-dominant hands.
Completion time (in seconds) will be recorded for each hand.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Altre misure di risultato
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
|---|---|---|
|
Assessment of Sleep Quality
Lasso di tempo: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI).
The questionnaire evaluates subjective sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbances, use of sleep medication, and daytime dysfunction.
Total scores range from 0 to 21, with scores above 5 indicating poor sleep quality.
|
Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
|
Collaboratori e investigatori
Qui è dove troverai le persone e le organizzazioni coinvolte in questo studio.
Studiare le date dei record
Queste date tengono traccia dell'avanzamento della registrazione dello studio e dell'invio dei risultati di sintesi a ClinicalTrials.gov. I record degli studi e i risultati riportati vengono esaminati dalla National Library of Medicine (NLM) per assicurarsi che soddisfino specifici standard di controllo della qualità prima di essere pubblicati sul sito Web pubblico.
Studia le date principali
Inizio studio (Stimato)
31 luglio 2026
Completamento primario (Stimato)
31 dicembre 2026
Completamento dello studio (Stimato)
31 marzo 2027
Date di iscrizione allo studio
Primo inviato
11 giugno 2026
Primo inviato che soddisfa i criteri di controllo qualità
15 luglio 2026
Primo Inserito (Effettivo)
22 luglio 2026
Aggiornamenti dei record di studio
Ultimo aggiornamento pubblicato (Effettivo)
22 luglio 2026
Ultimo aggiornamento inviato che soddisfa i criteri QC
15 luglio 2026
Ultimo verificato
1 giugno 2026
Maggiori informazioni
Termini relativi a questo studio
Parole chiave
Termini MeSH pertinenti aggiuntivi
Altri numeri di identificazione dello studio
- TOOLANG
Piano per i dati dei singoli partecipanti (IPD)
Hai intenzione di condividere i dati dei singoli partecipanti (IPD)?
NO
Descrizione del piano IPD
No plan to share individual participant data (IPD).
Data will not be shared due to ethical and confidentiality considerations related to participant privacy and the terms of informed consent.
Informazioni su farmaci e dispositivi, documenti di studio
Studia un prodotto farmaceutico regolamentato dalla FDA degli Stati Uniti
No
Studia un dispositivo regolamentato dalla FDA degli Stati Uniti
No
Queste informazioni sono state recuperate direttamente dal sito web clinicaltrials.gov senza alcuna modifica. In caso di richieste di modifica, rimozione o aggiornamento dei dettagli dello studio, contattare register@clinicaltrials.gov. Non appena verrà implementata una modifica su clinicaltrials.gov, questa verrà aggiornata automaticamente anche sul nostro sito web .