Stroke Care During the COVID-19 Pandemic
Stroke and TIA Care During the COVID-19 Pandemic: Regional Patterns and Epidemiological Determinants
Background: The SARS-CoV-2 pandemic led to substantial changes in the allocation of healthcare resources and affected the behavior of patients experiencing stroke symptoms. Previous studies have mainly focused on the so-called "first wave" of the pandemic during the first half of 2020. During this period, the number of hospital admissions of patients with transient ischemic attacks (TIAs) and minor strokes decreased significantly in many hospitals. This reduction was attributed not only to the reallocation of healthcare resources toward the care of patients with COVID-19, but also to patients' concerns about becoming infected with SARS-CoV-2 during a hospital stay. Since then, the situation has changed, as hospitals have become better prepared to treat patients with COVID-19 and the public has become better informed about the risks of SARS-CoV-2 infection. It is therefore possible that the pattern of acute stroke care during the subsequent wave of COVID-19, which began in autumn 2020, differed from that observed during the first wave.
Aim: The aim of this project is to analyze changes in patterns of acute stroke care across different regions of Europe during the first and subsequent waves of the COVID-19 pandemic and to identify epidemiological determinants associated with changes in stroke care.
Methods: We will collect and analyze data on hospital admissions of patients with acute ischemic stroke, hemorrhagic stroke, and transient ischemic attacks (TIAs) from approximately 40 participating stroke units across Europe for the period from January 1, 2019, to June 30, 2021.
The following parameters will be collected:
Number of hospital admissions per month and mean length of hospital stay (LOS) per month from January 1, 2019, to June 30, 2021, for the following diagnoses:
ischemic stroke hemorrhagic stroke transient ischemic attack Monthly numbers of thrombolysis and thrombectomy procedures during the same period.
Epidemiological parameters: population density, population age, geography of the region, urban/rural region properties, traffic connection to the first European hot spot of Covid-19, number of nursing homes Care characteritics: hospital size, stroke unit capacity.
Statistical analysis: Changes in the number of stroke admissions and length of hospital stay, as well as rates of thrombolysis and thrombectomy, will be analyzed in relation to regional COVID-19 incidence and mortality rates and other epidemiological parameters, including epidemiological connectivity to the first European COVID-19 hotspot.
Expected outcomes: We aim to identify regional patterns of change in acute stroke care during different phases of the COVID-19 pandemic and to determine epidemiological factors associated with these changes.
調査の概要
詳細な説明
研究の種類
入学 (推定)
連絡先と場所
研究場所
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Bergamo、イタリア
- 募集
- UOC Neurologia, ASST Papa Giovanni XXIII
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コンタクト：
- Maria Sessa, Professor
- 電話番号：+39035267111
- メール：msessa@asst-pg23.it
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Barcelona、スペイン
- 募集
- University of Barcelona, Comprehensive Stroke Center, Hospital Clinic
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コンタクト：
- Ángel Chamorro, Professor
- 電話番号：+34 932 27 54 00
- メール：achamorro@clinic.cat
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Prague、チェコ
- 募集
- Departement of Neurology 1st Medical Faculty and General Teaching Hospital
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コンタクト：
- Pavel Dušek, MD
- 電話番号：+420 224 965 501
- メール：pavel.dusek@vfn.cz
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Mainz、ドイツ
- 募集
- University Hospital Mainz
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コンタクト：
- Sergiu Groppa, Professor
- 電話番号：+496131170
- メール：Sergiu.Groppa@uks.eu
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参加基準
適格基準
就学可能な年齢
- 子
- 大人
- 高齢者
健康ボランティアの受け入れ
サンプリング方法
調査対象母集団
説明
Inclusion Criteria:
stroke transient ischemic attack
Exclusion Criteria:
traumatic cause of stroke
研究計画
研究はどのように設計されていますか？
デザインの詳細
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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hospital admissions
時間枠：2,5 years
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hospital admissions for stroke ot TIA
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2,5 years
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協力者と研究者
スポンサー
出版物と役立つリンク
一般刊行物
- Hbid Y, Stanley K, Wolfe CDA, Bhalla A, James M, Douiri A; SSNAP Collaboration. Stroke care in the United Kingdom before, during, and after the COVID-19 lockdowns: A retrospective nationwide cohort study. PLoS One. 2025 Sep 2;20(9):e0330903. doi: 10.1371/journal.pone.0330903. eCollection 2025.
- Dengler J, Abdullah B, Kukolja J, Kuhlen R, Hohenstein S, Dengler NF, Bollmann A, Palm F. Frailty in Stroke Care in Germany Between 2016 and 2022-A Retrospective, Hospital-Based Nationwide Cohort Study. NeuroSci. 2025 Sep 8;6(3):88. doi: 10.3390/neurosci6030088.
- Abe K, Shibata S, Miyawaki A, Kawachi I. Changes in inpatient and outpatient stroke admissions during COVID-19: a difference-in-differences analysis based on claims data from 242 acute care hospitals in Japan. BMJ Public Health. 2025 Sep 29;3(2):e001958. doi: 10.1136/bmjph-2024-001958. eCollection 2025.
- Reddi P, Mehta A, Hardigan T, Shafizadeh M, Kellner CP, Dangayach NS, Fifi JT, Mocco J, Majidi S. Acute Ischemic Stroke and Endovascular Thrombectomy During COVID-19 Pandemic: A Nationwide Analysis. Neurosurg Pract. 2025 May 23;6(2):e00144. doi: 10.1227/neuprac.0000000000000144. eCollection 2025 Jun.
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (推定)
研究の完了 (推定)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
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