Stroke Care During the COVID-19 Pandemic
Stroke and TIA Care During the COVID-19 Pandemic: Regional Patterns and Epidemiological Determinants
Background: The SARS-CoV-2 pandemic led to substantial changes in the allocation of healthcare resources and affected the behavior of patients experiencing stroke symptoms. Previous studies have mainly focused on the so-called "first wave" of the pandemic during the first half of 2020. During this period, the number of hospital admissions of patients with transient ischemic attacks (TIAs) and minor strokes decreased significantly in many hospitals. This reduction was attributed not only to the reallocation of healthcare resources toward the care of patients with COVID-19, but also to patients' concerns about becoming infected with SARS-CoV-2 during a hospital stay. Since then, the situation has changed, as hospitals have become better prepared to treat patients with COVID-19 and the public has become better informed about the risks of SARS-CoV-2 infection. It is therefore possible that the pattern of acute stroke care during the subsequent wave of COVID-19, which began in autumn 2020, differed from that observed during the first wave.
Aim: The aim of this project is to analyze changes in patterns of acute stroke care across different regions of Europe during the first and subsequent waves of the COVID-19 pandemic and to identify epidemiological determinants associated with changes in stroke care.
Methods: We will collect and analyze data on hospital admissions of patients with acute ischemic stroke, hemorrhagic stroke, and transient ischemic attacks (TIAs) from approximately 40 participating stroke units across Europe for the period from January 1, 2019, to June 30, 2021.
The following parameters will be collected:
Number of hospital admissions per month and mean length of hospital stay (LOS) per month from January 1, 2019, to June 30, 2021, for the following diagnoses:
ischemic stroke hemorrhagic stroke transient ischemic attack Monthly numbers of thrombolysis and thrombectomy procedures during the same period.
Epidemiological parameters: population density, population age, geography of the region, urban/rural region properties, traffic connection to the first European hot spot of Covid-19, number of nursing homes Care characteritics: hospital size, stroke unit capacity.
Statistical analysis: Changes in the number of stroke admissions and length of hospital stay, as well as rates of thrombolysis and thrombectomy, will be analyzed in relation to regional COVID-19 incidence and mortality rates and other epidemiological parameters, including epidemiological connectivity to the first European COVID-19 hotspot.
Expected outcomes: We aim to identify regional patterns of change in acute stroke care during different phases of the COVID-19 pandemic and to determine epidemiological factors associated with these changes.
Studieoversigt
Status
Betingelser
Intervention / Behandling
Detaljeret beskrivelse
Undersøgelsestype
Tilmelding (Anslået)
Kontakter og lokationer
Studiesteder
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Bergamo, Italien
- Rekruttering
- UOC Neurologia, ASST Papa Giovanni XXIII
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Kontakt:
- Maria Sessa, Professor
- Telefonnummer: +39035267111
- E-mail: msessa@asst-pg23.it
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Barcelona, Spanien
- Rekruttering
- University of Barcelona, Comprehensive Stroke Center, Hospital Clinic
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Kontakt:
- Ángel Chamorro, Professor
- Telefonnummer: +34 932 27 54 00
- E-mail: achamorro@clinic.cat
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Prague, Tjekkiet
- Rekruttering
- Departement of Neurology 1st Medical Faculty and General Teaching Hospital
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Kontakt:
- Pavel Dušek, MD
- Telefonnummer: +420 224 965 501
- E-mail: pavel.dusek@vfn.cz
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Mainz, Tyskland
- Rekruttering
- University Hospital Mainz
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Kontakt:
- Sergiu Groppa, Professor
- Telefonnummer: +496131170
- E-mail: Sergiu.Groppa@uks.eu
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Deltagelseskriterier
Berettigelseskriterier
Aldre berettiget til at studere
- Barn
- Voksen
- Ældre voksen
Tager imod sunde frivillige
Prøveudtagningsmetode
Studiebefolkning
Beskrivelse
Inclusion Criteria:
stroke transient ischemic attack
Exclusion Criteria:
traumatic cause of stroke
Studieplan
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
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hospital admissions
Tidsramme: 2,5 years
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hospital admissions for stroke ot TIA
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2,5 years
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Samarbejdspartnere og efterforskere
Sponsor
Publikationer og nyttige links
Generelle publikationer
- Hbid Y, Stanley K, Wolfe CDA, Bhalla A, James M, Douiri A; SSNAP Collaboration. Stroke care in the United Kingdom before, during, and after the COVID-19 lockdowns: A retrospective nationwide cohort study. PLoS One. 2025 Sep 2;20(9):e0330903. doi: 10.1371/journal.pone.0330903. eCollection 2025.
- Dengler J, Abdullah B, Kukolja J, Kuhlen R, Hohenstein S, Dengler NF, Bollmann A, Palm F. Frailty in Stroke Care in Germany Between 2016 and 2022-A Retrospective, Hospital-Based Nationwide Cohort Study. NeuroSci. 2025 Sep 8;6(3):88. doi: 10.3390/neurosci6030088.
- Abe K, Shibata S, Miyawaki A, Kawachi I. Changes in inpatient and outpatient stroke admissions during COVID-19: a difference-in-differences analysis based on claims data from 242 acute care hospitals in Japan. BMJ Public Health. 2025 Sep 29;3(2):e001958. doi: 10.1136/bmjph-2024-001958. eCollection 2025.
- Reddi P, Mehta A, Hardigan T, Shafizadeh M, Kellner CP, Dangayach NS, Fifi JT, Mocco J, Majidi S. Acute Ischemic Stroke and Endovascular Thrombectomy During COVID-19 Pandemic: A Nationwide Analysis. Neurosurg Pract. 2025 May 23;6(2):e00144. doi: 10.1227/neuprac.0000000000000144. eCollection 2025 Jun.
Datoer for undersøgelser
Studer store datoer
Studiestart (Faktiske)
Primær færdiggørelse (Anslået)
Studieafslutning (Anslået)
Datoer for studieregistrering
Først indsendt
Først indsendt, der opfyldte QC-kriterier
Først opslået (Faktiske)
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
Sidst verificeret
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- STROCOV19
Plan for individuelle deltagerdata (IPD)
Planlægger du at dele individuelle deltagerdata (IPD)?
IPD-planbeskrivelse
Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter
Studerer et amerikansk FDA-reguleret lægemiddelprodukt
Studerer et amerikansk FDA-reguleret enhedsprodukt
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