Neural Mechanisms of Social Feedback Evaluation in Young Adults Across the Schizotypy Spectrum: An EEG Social Judgment Study
2026年9月14日 更新者：Central Connecticut State University
Neural Mechanisms of Social Feedback Evaluation in Schizotypy: An EEG Study of Oscillatory and Event-Related Potentials
This study will examine how young adults with different levels of schizotypal traits process social acceptance and rejection.
Participants between 18 and 35 years old will complete a single laboratory session that includes questionnaires and electroencephalography (EEG), a noninvasive method that measures electrical brain activity through sensors placed on the scalp.
During EEG recording, participants will complete a computer-based Social Judgment Paradigm (SJP) in which they form expectations about whether another person will like or dislike them and then receive experimentally controlled acceptance or rejection feedback.
The study will examine how brain responses differ when social feedback is expected versus unexpected and whether these responses vary with schizotypal traits.
The goal is to better understand the brain mechanisms involved in evaluating social feedback.
This study does not provide treatment and does not test a drug or medical device.
調査の概要
詳細な説明
Schizotypal traits occur along a continuum in the general population and are associated with differences in social functioning and social information processing. This study will investigate neural responses to social feedback in young adults across the schizotypy spectrum using electroencephalography (EEG).
Participants between 18 and 35 years old will complete a single experimental session. During EEG recording, they will perform a Social Judgment Paradigm (SJP) in which they first form an expectation about whether another person will respond positively or negatively toward them and subsequently receive acceptance or rejection feedback. This produces four within-participant feedback conditions: expected acceptance, expected rejection, unexpected acceptance, and unexpected rejection.
The study will examine brain activity associated with evaluating social feedback, including frontal-midline (FM) theta activity and event-related potentials (ERPs). The primary analyses will test whether neural responses to acceptance and rejection, particularly when feedback violates expectations, vary as a function of continuous schizotypal traits. Participants will also complete self-report measures assessing schizotypal traits, social functioning, and related psychological characteristics.
The study is designed to clarify neural mechanisms involved in social feedback evaluation and to determine how individual differences in schizotypal traits are associated with these processes.
研究の種類
介入
入学 (推定)
100
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究連絡先
- 名前：Silvia Corbera LOpez Principal Investigator, PhD.
- 電話番号：860-832-3111
- メール：silviac@ccsu.edu
研究連絡先のバックアップ
- 名前：Brenda Lopez Grants and Funded Research Administrator
- 電話番号：(860) 832-2366
- メール：b.lopez@ccsu.edu
研究場所
-
-
Connecticut
-
New Britain、Connecticut、アメリカ、06050
- Central Connecticut State University
-
コンタクト：
- Silvia Corbera Lopez, Principal Investigator, Ph.D.
- 電話番号：860-832-3111
- メール：silviac@ccsu.edu
-
コンタクト：
- Brenda Lopez Grants and Funded Research Administrator
- 電話番号：860.832.2366
- メール：b.lopez@ccsu.edu
-
主任研究者：
- Silvia Corbera Lopez, Ph.D.
-
-
参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
- 大人
健康ボランティアの受け入れ
はい
説明
Inclusion Criteria:
- Ages 18-35 years.
- Able to provide informed consent.
- Able to complete an EEG recording session.
Exclusion Criteria:
- Younger than 18 years or older than 35 years.
- Unable to provide informed consent.
- Unable to complete the EEG recording session.
- No additional exclusion criteria are applied.
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：基礎科学
- 割り当て：なし
- 介入モデル：単一グループの割り当て
- マスキング：なし（オープンラベル）
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
実験的：Social Judgment Paradigm
Participants complete a single-session Social Judgment Paradigm during EEG recording.
All participants experience four within-subject experimental conditions defined by feedback expectancy (expected versus unexpected) and feedback valence (acceptance versus rejection): expected acceptance, expected rejection, unexpected acceptance, and unexpected rejection.
The order of feedback trials is randomized within the task.
|
A computerized Social Judgment Paradigm in which participants receive experimentally controlled social feedback (acceptance/rejection) from purported peers or evaluators while continuous EEG is recorded to assess oscillatory activity and event-related potentials associated with social feedback processing.
Feedback valence and expectancy are manipulated at the trial level, with trial order randomized within the task.
他の名前：
|
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Frontal Midline Theta Power (4-7 Hz)
時間枠：Day 1
|
Mean frontal-midline theta-band power (4-7 Hz) derived from EEG data time-locked to feedback onset during the Social Judgment Paradigm, quantified during the prespecified 200-600 ms post-feedback window at frontocentral electrodes.
Theta power will be measured directly across the four feedback conditions defined by expectancy (expected/unexpected) and feedback valence (acceptance/rejection).
|
Day 1
|
|
Feedback-Related Negativity (FRN) Amplitude
時間枠：Day 1
|
Mean event-related potential (ERP) amplitude within the 250-350 ms time window following feedback onset during the Social Judgment Paradigm, quantified at frontocentral electrodes.
FRN amplitude will be measured directly across the four feedback conditions defined by expectancy and feedback valence.
|
Day 1
|
|
Late Positive Potential (LPP) Amplitude
時間枠：Day 1
|
Mean event-related potential (ERP) amplitude within the 350-600 ms time window following feedback onset during the Social Judgment Paradigm, quantified at midline electrodes.
LPP amplitude will be measured directly across the four feedback conditions defined by expectancy and feedback valence.
|
Day 1
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Behavioral Expectancy Responses
時間枠：Day 1
|
Participant predictions of social acceptance or rejection during each trial of the Social Judgment Paradigm, including expectancy response and reaction time.
|
Day 1
|
|
Schizotypal Personality Questionnaire (SPQ) Total Score
時間枠：Day 1
|
The Schizotypal Personality Questionnaire (SPQ) is a 74-item self-report measure assessing schizotypal personality traits across cognitive-perceptual, interpersonal, and disorganized dimensions.
Items are answered in a yes/no format and scored dichotomously.
Item scores are summed to produce a total score ranging from 0 to 74.
Higher scores indicate greater levels of schizotypal personality traits.
|
Day 1
|
|
Multidimensional Schizotypy Scale (MSS) Scores
時間枠：Day 1
|
The Multidimensional Schizotypy Scale (MSS) is a 77-item self-report measure assessing positive, negative, and disorganized dimensions of schizotypy.
Items are answered using a true/false response format.
The Positive Schizotypy subscale contains 26 items and ranges from 0 to 26; the Negative Schizotypy subscale contains 26 items and ranges from 0 to 26; and the Disorganized Schizotypy subscale contains 25 items and ranges from 0 to 25.
Higher scores on each subscale indicate greater levels of the corresponding dimension of schizotypy.
|
Day 1
|
|
Brief Fear of Negative Evaluation Scale-Revised (BFNES-R) Total Score
時間枠：Day 1
|
The Brief Fear of Negative Evaluation Scale-Revised (BFNES-R) is a 12-item self-report measure assessing fear of negative evaluation by others.
Each item is rated on a 5-point Likert scale ranging from 0 (not at all characteristic of me) to 4 (extremely characteristic of me).
Item ratings are summed to produce a total score ranging from 0 to 48.
Higher scores indicate greater fear of negative evaluation and greater concern about others' social evaluation.
|
Day 1
|
|
Perceived Stress Reactivity Scale (PSRS) Total Score
時間枠：Day 1
|
The Perceived Stress Reactivity Scale (PSRS) is a 23-item self-report measure assessing an individual's typical response intensity to potentially stressful situations in everyday life.
The scale includes five domains: prolonged reactivity, reactivity to failure, reactivity to social conflict, reactivity to work overload, and reactivity to social evaluation.
Items are scored from 0 to 2, with negatively keyed items reverse-scored, and summed to produce a total score ranging from 0 to 46.
Higher scores indicate greater perceived stress reactivity
|
Day 1
|
|
Social Functioning Questionnaire (SFQ) Total Score
時間枠：Day 1
|
The Social Functioning Questionnaire (SFQ) is an 8-item self-report measure assessing perceived social functioning across domains including work and home activities, finances, close relationships, family relationships, social isolation, sexual functioning, and leisure activities.
Each item is scored from 0 to 3, and item scores are summed to produce a total score ranging from 0 to 24.
Higher scores indicate poorer social functioning.
|
Day 1
|
協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
出版物と役立つリンク
研究に関する情報を入力する責任者は、自発的にこれらの出版物を提供します。これらは、研究に関連するあらゆるものに関するものである可能性があります。
一般刊行物
- Somerville LH, Heatherton TF, Kelley WM. Anterior cingulate cortex responds differentially to expectancy violation and social rejection. Nat Neurosci. 2006 Aug;9(8):1007-8. doi: 10.1038/nn1728. Epub 2006 Jul 2.
- van der Molen MJW, Dekkers LMS, Westenberg PM, van der Veen FM, van der Molen MW. Why don't you like me? Midfrontal theta power in response to unexpected peer rejection feedback. Neuroimage. 2017 Feb 1;146:474-483. doi: 10.1016/j.neuroimage.2016.08.045. Epub 2016 Aug 23.
- Kortink ED, Weeda WD, Crowley MJ, Gunther Moor B, van der Molen MJW. Community structure analysis of rejection sensitive personality profiles: A common neural response to social evaluative threat? Cogn Affect Behav Neurosci. 2018 Jun;18(3):581-595. doi: 10.3758/s13415-018-0589-1.
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (推定)
2027年1月1日
一次修了 (推定)
2029年12月1日
研究の完了 (推定)
2029年12月1日
試験登録日
最初に提出
2026年9月9日
QC基準を満たした最初の提出物
2026年9月14日
最初の投稿 (実際)
2026年9月16日
学習記録の更新
投稿された最後の更新 (実際)
2026年9月16日
QC基準を満たした最後の更新が送信されました
2026年9月14日
最終確認日
2026年9月1日
詳しくは
本研究に関する用語
その他の研究ID番号
- CORBERA-R15-SJP-2026
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
はい
IPD プランの説明
De-identified individual participant data will be shared through the NIMH Data Archive (NDA).
Shared data will include demographic, behavioral, clinical/phenotypic, and questionnaire data; expectancy ratings and trial-level responses from the Social Judgment Paradigm; raw 64-channel EEG data; and processed EEG derivatives underlying project findings, including ERP and time-frequency measures.
Direct identifiers will not be shared.
IPD 共有時間枠
Data underlying peer-reviewed publications will be shared by the time of publication.
Other study data, including unpublished data, will be shared no later than the end of the period of performance, including any no-cost extensions.
IPD 共有アクセス基準
Individual participant data will be available through the NIMH Data Archive (NDA) in accordance with NDA data access policies and procedures.
Access to participant-level data will be governed by NDA requirements designed to protect participants' privacy, rights, and confidentiality.
Direct identifiers will not be shared.
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
いいえ
米国FDA規制機器製品の研究
いいえ
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。