Neural Mechanisms of Social Feedback Evaluation in Young Adults Across the Schizotypy Spectrum: An EEG Social Judgment Study
14. september 2026 oppdatert av: Central Connecticut State University
Neural Mechanisms of Social Feedback Evaluation in Schizotypy: An EEG Study of Oscillatory and Event-Related Potentials
This study will examine how young adults with different levels of schizotypal traits process social acceptance and rejection.
Participants between 18 and 35 years old will complete a single laboratory session that includes questionnaires and electroencephalography (EEG), a noninvasive method that measures electrical brain activity through sensors placed on the scalp.
During EEG recording, participants will complete a computer-based Social Judgment Paradigm (SJP) in which they form expectations about whether another person will like or dislike them and then receive experimentally controlled acceptance or rejection feedback.
The study will examine how brain responses differ when social feedback is expected versus unexpected and whether these responses vary with schizotypal traits.
The goal is to better understand the brain mechanisms involved in evaluating social feedback.
This study does not provide treatment and does not test a drug or medical device.
Studieoversikt
Status
Har ikke rekruttert ennå
Forhold
Intervensjon / Behandling
Detaljert beskrivelse
Schizotypal traits occur along a continuum in the general population and are associated with differences in social functioning and social information processing. This study will investigate neural responses to social feedback in young adults across the schizotypy spectrum using electroencephalography (EEG).
Participants between 18 and 35 years old will complete a single experimental session. During EEG recording, they will perform a Social Judgment Paradigm (SJP) in which they first form an expectation about whether another person will respond positively or negatively toward them and subsequently receive acceptance or rejection feedback. This produces four within-participant feedback conditions: expected acceptance, expected rejection, unexpected acceptance, and unexpected rejection.
The study will examine brain activity associated with evaluating social feedback, including frontal-midline (FM) theta activity and event-related potentials (ERPs). The primary analyses will test whether neural responses to acceptance and rejection, particularly when feedback violates expectations, vary as a function of continuous schizotypal traits. Participants will also complete self-report measures assessing schizotypal traits, social functioning, and related psychological characteristics.
The study is designed to clarify neural mechanisms involved in social feedback evaluation and to determine how individual differences in schizotypal traits are associated with these processes.
Studietype
Intervensjonell
Registrering (Antatt)
100
Fase
- Ikke aktuelt
Kontakter og plasseringer
Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.
Studiekontakt
- Navn: Silvia Corbera LOpez Principal Investigator, PhD.
- Telefonnummer: 860-832-3111
- E-post: silviac@ccsu.edu
Studer Kontakt Backup
- Navn: Brenda Lopez Grants and Funded Research Administrator
- Telefonnummer: (860) 832-2366
- E-post: b.lopez@ccsu.edu
Studiesteder
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Connecticut
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New Britain, Connecticut, Forente stater, 06050
- Central Connecticut State University
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Ta kontakt med:
- Silvia Corbera Lopez, Principal Investigator, Ph.D.
- Telefonnummer: 860-832-3111
- E-post: silviac@ccsu.edu
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Ta kontakt med:
- Brenda Lopez Grants and Funded Research Administrator
- Telefonnummer: 860.832.2366
- E-post: b.lopez@ccsu.edu
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Hovedetterforsker:
- Silvia Corbera Lopez, Ph.D.
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Deltakelseskriterier
Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
- Voksen
Tar imot friske frivillige
Ja
Beskrivelse
Inclusion Criteria:
- Ages 18-35 years.
- Able to provide informed consent.
- Able to complete an EEG recording session.
Exclusion Criteria:
- Younger than 18 years or older than 35 years.
- Unable to provide informed consent.
- Unable to complete the EEG recording session.
- No additional exclusion criteria are applied.
Studieplan
Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.
Hvordan er studiet utformet?
Designdetaljer
- Primært formål: Grunnvitenskap
- Tildeling: N/A
- Intervensjonsmodell: Enkeltgruppeoppdrag
- Masking: Ingen (Open Label)
Våpen og intervensjoner
Deltakergruppe / Arm |
Intervensjon / Behandling |
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Eksperimentell: Social Judgment Paradigm
Participants complete a single-session Social Judgment Paradigm during EEG recording.
All participants experience four within-subject experimental conditions defined by feedback expectancy (expected versus unexpected) and feedback valence (acceptance versus rejection): expected acceptance, expected rejection, unexpected acceptance, and unexpected rejection.
The order of feedback trials is randomized within the task.
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A computerized Social Judgment Paradigm in which participants receive experimentally controlled social feedback (acceptance/rejection) from purported peers or evaluators while continuous EEG is recorded to assess oscillatory activity and event-related potentials associated with social feedback processing.
Feedback valence and expectancy are manipulated at the trial level, with trial order randomized within the task.
Andre navn:
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Hva måler studien?
Primære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
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Frontal Midline Theta Power (4-7 Hz)
Tidsramme: Day 1
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Mean frontal-midline theta-band power (4-7 Hz) derived from EEG data time-locked to feedback onset during the Social Judgment Paradigm, quantified during the prespecified 200-600 ms post-feedback window at frontocentral electrodes.
Theta power will be measured directly across the four feedback conditions defined by expectancy (expected/unexpected) and feedback valence (acceptance/rejection).
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Day 1
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Feedback-Related Negativity (FRN) Amplitude
Tidsramme: Day 1
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Mean event-related potential (ERP) amplitude within the 250-350 ms time window following feedback onset during the Social Judgment Paradigm, quantified at frontocentral electrodes.
FRN amplitude will be measured directly across the four feedback conditions defined by expectancy and feedback valence.
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Day 1
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Late Positive Potential (LPP) Amplitude
Tidsramme: Day 1
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Mean event-related potential (ERP) amplitude within the 350-600 ms time window following feedback onset during the Social Judgment Paradigm, quantified at midline electrodes.
LPP amplitude will be measured directly across the four feedback conditions defined by expectancy and feedback valence.
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Day 1
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Sekundære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
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Behavioral Expectancy Responses
Tidsramme: Day 1
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Participant predictions of social acceptance or rejection during each trial of the Social Judgment Paradigm, including expectancy response and reaction time.
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Day 1
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Schizotypal Personality Questionnaire (SPQ) Total Score
Tidsramme: Day 1
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The Schizotypal Personality Questionnaire (SPQ) is a 74-item self-report measure assessing schizotypal personality traits across cognitive-perceptual, interpersonal, and disorganized dimensions.
Items are answered in a yes/no format and scored dichotomously.
Item scores are summed to produce a total score ranging from 0 to 74.
Higher scores indicate greater levels of schizotypal personality traits.
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Day 1
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Multidimensional Schizotypy Scale (MSS) Scores
Tidsramme: Day 1
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The Multidimensional Schizotypy Scale (MSS) is a 77-item self-report measure assessing positive, negative, and disorganized dimensions of schizotypy.
Items are answered using a true/false response format.
The Positive Schizotypy subscale contains 26 items and ranges from 0 to 26; the Negative Schizotypy subscale contains 26 items and ranges from 0 to 26; and the Disorganized Schizotypy subscale contains 25 items and ranges from 0 to 25.
Higher scores on each subscale indicate greater levels of the corresponding dimension of schizotypy.
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Day 1
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Brief Fear of Negative Evaluation Scale-Revised (BFNES-R) Total Score
Tidsramme: Day 1
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The Brief Fear of Negative Evaluation Scale-Revised (BFNES-R) is a 12-item self-report measure assessing fear of negative evaluation by others.
Each item is rated on a 5-point Likert scale ranging from 0 (not at all characteristic of me) to 4 (extremely characteristic of me).
Item ratings are summed to produce a total score ranging from 0 to 48.
Higher scores indicate greater fear of negative evaluation and greater concern about others' social evaluation.
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Day 1
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Perceived Stress Reactivity Scale (PSRS) Total Score
Tidsramme: Day 1
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The Perceived Stress Reactivity Scale (PSRS) is a 23-item self-report measure assessing an individual's typical response intensity to potentially stressful situations in everyday life.
The scale includes five domains: prolonged reactivity, reactivity to failure, reactivity to social conflict, reactivity to work overload, and reactivity to social evaluation.
Items are scored from 0 to 2, with negatively keyed items reverse-scored, and summed to produce a total score ranging from 0 to 46.
Higher scores indicate greater perceived stress reactivity
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Day 1
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Social Functioning Questionnaire (SFQ) Total Score
Tidsramme: Day 1
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The Social Functioning Questionnaire (SFQ) is an 8-item self-report measure assessing perceived social functioning across domains including work and home activities, finances, close relationships, family relationships, social isolation, sexual functioning, and leisure activities.
Each item is scored from 0 to 3, and item scores are summed to produce a total score ranging from 0 to 24.
Higher scores indicate poorer social functioning.
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Day 1
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Samarbeidspartnere og etterforskere
Det er her du vil finne personer og organisasjoner som er involvert i denne studien.
Publikasjoner og nyttige lenker
Den som er ansvarlig for å legge inn informasjon om studien leverer frivillig disse publikasjonene. Disse kan handle om alt relatert til studiet.
Generelle publikasjoner
- Somerville LH, Heatherton TF, Kelley WM. Anterior cingulate cortex responds differentially to expectancy violation and social rejection. Nat Neurosci. 2006 Aug;9(8):1007-8. doi: 10.1038/nn1728. Epub 2006 Jul 2.
- van der Molen MJW, Dekkers LMS, Westenberg PM, van der Veen FM, van der Molen MW. Why don't you like me? Midfrontal theta power in response to unexpected peer rejection feedback. Neuroimage. 2017 Feb 1;146:474-483. doi: 10.1016/j.neuroimage.2016.08.045. Epub 2016 Aug 23.
- Kortink ED, Weeda WD, Crowley MJ, Gunther Moor B, van der Molen MJW. Community structure analysis of rejection sensitive personality profiles: A common neural response to social evaluative threat? Cogn Affect Behav Neurosci. 2018 Jun;18(3):581-595. doi: 10.3758/s13415-018-0589-1.
Studierekorddatoer
Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.
Studer hoveddatoer
Studiestart (Antatt)
1. januar 2027
Primær fullføring (Antatt)
1. desember 2029
Studiet fullført (Antatt)
1. desember 2029
Datoer for studieregistrering
Først innsendt
9. september 2026
Først innsendt som oppfylte QC-kriteriene
14. september 2026
Først lagt ut (Faktiske)
16. september 2026
Oppdateringer av studieposter
Sist oppdatering lagt ut (Faktiske)
16. september 2026
Siste oppdatering sendt inn som oppfylte QC-kriteriene
14. september 2026
Sist bekreftet
1. september 2026
Mer informasjon
Begreper knyttet til denne studien
Nøkkelord
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- CORBERA-R15-SJP-2026
Plan for individuelle deltakerdata (IPD)
Planlegger du å dele individuelle deltakerdata (IPD)?
JA
IPD-planbeskrivelse
De-identified individual participant data will be shared through the NIMH Data Archive (NDA).
Shared data will include demographic, behavioral, clinical/phenotypic, and questionnaire data; expectancy ratings and trial-level responses from the Social Judgment Paradigm; raw 64-channel EEG data; and processed EEG derivatives underlying project findings, including ERP and time-frequency measures.
Direct identifiers will not be shared.
IPD-delingstidsramme
Data underlying peer-reviewed publications will be shared by the time of publication.
Other study data, including unpublished data, will be shared no later than the end of the period of performance, including any no-cost extensions.
Tilgangskriterier for IPD-deling
Individual participant data will be available through the NIMH Data Archive (NDA) in accordance with NDA data access policies and procedures.
Access to participant-level data will be governed by NDA requirements designed to protect participants' privacy, rights, and confidentiality.
Direct identifiers will not be shared.
Legemiddel- og utstyrsinformasjon, studiedokumenter
Studerer et amerikansk FDA-regulert medikamentprodukt
Nei
Studerer et amerikansk FDA-regulert enhetsprodukt
Nei
Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .