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Neural Mechanisms of Social Feedback Evaluation in Young Adults Across the Schizotypy Spectrum: An EEG Social Judgment Study

14 settembre 2026 aggiornato da: Central Connecticut State University

Neural Mechanisms of Social Feedback Evaluation in Schizotypy: An EEG Study of Oscillatory and Event-Related Potentials

This study will examine how young adults with different levels of schizotypal traits process social acceptance and rejection. Participants between 18 and 35 years old will complete a single laboratory session that includes questionnaires and electroencephalography (EEG), a noninvasive method that measures electrical brain activity through sensors placed on the scalp. During EEG recording, participants will complete a computer-based Social Judgment Paradigm (SJP) in which they form expectations about whether another person will like or dislike them and then receive experimentally controlled acceptance or rejection feedback. The study will examine how brain responses differ when social feedback is expected versus unexpected and whether these responses vary with schizotypal traits. The goal is to better understand the brain mechanisms involved in evaluating social feedback. This study does not provide treatment and does not test a drug or medical device.

Panoramica dello studio

Stato

Non ancora reclutamento

Condizioni

Intervento / Trattamento

Descrizione dettagliata

Schizotypal traits occur along a continuum in the general population and are associated with differences in social functioning and social information processing. This study will investigate neural responses to social feedback in young adults across the schizotypy spectrum using electroencephalography (EEG).

Participants between 18 and 35 years old will complete a single experimental session. During EEG recording, they will perform a Social Judgment Paradigm (SJP) in which they first form an expectation about whether another person will respond positively or negatively toward them and subsequently receive acceptance or rejection feedback. This produces four within-participant feedback conditions: expected acceptance, expected rejection, unexpected acceptance, and unexpected rejection.

The study will examine brain activity associated with evaluating social feedback, including frontal-midline (FM) theta activity and event-related potentials (ERPs). The primary analyses will test whether neural responses to acceptance and rejection, particularly when feedback violates expectations, vary as a function of continuous schizotypal traits. Participants will also complete self-report measures assessing schizotypal traits, social functioning, and related psychological characteristics.

The study is designed to clarify neural mechanisms involved in social feedback evaluation and to determine how individual differences in schizotypal traits are associated with these processes.

Tipo di studio

Interventistico

Iscrizione (Stimato)

100

Fase

  • Non applicabile

Contatti e Sedi

Questa sezione fornisce i recapiti di coloro che conducono lo studio e informazioni su dove viene condotto lo studio.

Contatto studio

  • Nome: Silvia Corbera LOpez Principal Investigator, PhD.
  • Numero di telefono: 860-832-3111
  • Email: silviac@ccsu.edu

Backup dei contatti dello studio

  • Nome: Brenda Lopez Grants and Funded Research Administrator
  • Numero di telefono: (860) 832-2366
  • Email: b.lopez@ccsu.edu

Luoghi di studio

  • Stati Uniti
    • Connecticut
      • New Britain, Connecticut, Stati Uniti, 06050
        • Central Connecticut State University
        • Contatto:
          • Silvia Corbera Lopez, Principal Investigator, Ph.D.
          • Numero di telefono: 860-832-3111
          • Email: silviac@ccsu.edu
        • Contatto:
          • Brenda Lopez Grants and Funded Research Administrator
          • Numero di telefono: 860.832.2366
          • Email: b.lopez@ccsu.edu
        • Investigatore principale:
          • Silvia Corbera Lopez, Ph.D.

Criteri di partecipazione

I ricercatori cercano persone che corrispondano a una certa descrizione, chiamata criteri di ammissibilità. Alcuni esempi di questi criteri sono le condizioni generali di salute di una persona o trattamenti precedenti.

Criteri di ammissibilità

Età idonea allo studio

  • Adulto

Accetta volontari sani

Sì

Descrizione

Inclusion Criteria:

  • Ages 18-35 years.
  • Able to provide informed consent.
  • Able to complete an EEG recording session.

Exclusion Criteria:

  • Younger than 18 years or older than 35 years.
  • Unable to provide informed consent.
  • Unable to complete the EEG recording session.
  • No additional exclusion criteria are applied.

Piano di studio

Questa sezione fornisce i dettagli del piano di studio, compreso il modo in cui lo studio è progettato e ciò che lo studio sta misurando.

Come è strutturato lo studio?

Dettagli di progettazione

  • Scopo principale: Scienza basilare
  • Assegnazione: N / A
  • Modello interventistico: Assegnazione di gruppo singolo
  • Mascheramento: Nessuno (etichetta aperta)

Armi e interventi

Gruppo di partecipanti / Arm
Intervento / Trattamento
Sperimentale: Social Judgment Paradigm
Participants complete a single-session Social Judgment Paradigm during EEG recording. All participants experience four within-subject experimental conditions defined by feedback expectancy (expected versus unexpected) and feedback valence (acceptance versus rejection): expected acceptance, expected rejection, unexpected acceptance, and unexpected rejection. The order of feedback trials is randomized within the task.
Comportamentale: Social Judgment Paradigm
A computerized Social Judgment Paradigm in which participants receive experimentally controlled social feedback (acceptance/rejection) from purported peers or evaluators while continuous EEG is recorded to assess oscillatory activity and event-related potentials associated with social feedback processing. Feedback valence and expectancy are manipulated at the trial level, with trial order randomized within the task.
Altri nomi:
  • SJP

Cosa sta misurando lo studio?

Misure di risultato primarie

Misura del risultato
Misura Descrizione
Lasso di tempo
Frontal Midline Theta Power (4-7 Hz)
Lasso di tempo: Day 1
Mean frontal-midline theta-band power (4-7 Hz) derived from EEG data time-locked to feedback onset during the Social Judgment Paradigm, quantified during the prespecified 200-600 ms post-feedback window at frontocentral electrodes. Theta power will be measured directly across the four feedback conditions defined by expectancy (expected/unexpected) and feedback valence (acceptance/rejection).
Day 1
Feedback-Related Negativity (FRN) Amplitude
Lasso di tempo: Day 1
Mean event-related potential (ERP) amplitude within the 250-350 ms time window following feedback onset during the Social Judgment Paradigm, quantified at frontocentral electrodes. FRN amplitude will be measured directly across the four feedback conditions defined by expectancy and feedback valence.
Day 1
Late Positive Potential (LPP) Amplitude
Lasso di tempo: Day 1
Mean event-related potential (ERP) amplitude within the 350-600 ms time window following feedback onset during the Social Judgment Paradigm, quantified at midline electrodes. LPP amplitude will be measured directly across the four feedback conditions defined by expectancy and feedback valence.
Day 1

Misure di risultato secondarie

Misura del risultato
Misura Descrizione
Lasso di tempo
Behavioral Expectancy Responses
Lasso di tempo: Day 1
Participant predictions of social acceptance or rejection during each trial of the Social Judgment Paradigm, including expectancy response and reaction time.
Day 1
Schizotypal Personality Questionnaire (SPQ) Total Score
Lasso di tempo: Day 1
The Schizotypal Personality Questionnaire (SPQ) is a 74-item self-report measure assessing schizotypal personality traits across cognitive-perceptual, interpersonal, and disorganized dimensions. Items are answered in a yes/no format and scored dichotomously. Item scores are summed to produce a total score ranging from 0 to 74. Higher scores indicate greater levels of schizotypal personality traits.
Day 1
Multidimensional Schizotypy Scale (MSS) Scores
Lasso di tempo: Day 1
The Multidimensional Schizotypy Scale (MSS) is a 77-item self-report measure assessing positive, negative, and disorganized dimensions of schizotypy. Items are answered using a true/false response format. The Positive Schizotypy subscale contains 26 items and ranges from 0 to 26; the Negative Schizotypy subscale contains 26 items and ranges from 0 to 26; and the Disorganized Schizotypy subscale contains 25 items and ranges from 0 to 25. Higher scores on each subscale indicate greater levels of the corresponding dimension of schizotypy.
Day 1
Brief Fear of Negative Evaluation Scale-Revised (BFNES-R) Total Score
Lasso di tempo: Day 1
The Brief Fear of Negative Evaluation Scale-Revised (BFNES-R) is a 12-item self-report measure assessing fear of negative evaluation by others. Each item is rated on a 5-point Likert scale ranging from 0 (not at all characteristic of me) to 4 (extremely characteristic of me). Item ratings are summed to produce a total score ranging from 0 to 48. Higher scores indicate greater fear of negative evaluation and greater concern about others' social evaluation.
Day 1
Perceived Stress Reactivity Scale (PSRS) Total Score
Lasso di tempo: Day 1
The Perceived Stress Reactivity Scale (PSRS) is a 23-item self-report measure assessing an individual's typical response intensity to potentially stressful situations in everyday life. The scale includes five domains: prolonged reactivity, reactivity to failure, reactivity to social conflict, reactivity to work overload, and reactivity to social evaluation. Items are scored from 0 to 2, with negatively keyed items reverse-scored, and summed to produce a total score ranging from 0 to 46. Higher scores indicate greater perceived stress reactivity
Day 1
Social Functioning Questionnaire (SFQ) Total Score
Lasso di tempo: Day 1
The Social Functioning Questionnaire (SFQ) is an 8-item self-report measure assessing perceived social functioning across domains including work and home activities, finances, close relationships, family relationships, social isolation, sexual functioning, and leisure activities. Each item is scored from 0 to 3, and item scores are summed to produce a total score ranging from 0 to 24. Higher scores indicate poorer social functioning.
Day 1

Collaboratori e investigatori

Qui è dove troverai le persone e le organizzazioni coinvolte in questo studio.

Sponsor

Central Connecticut State University

Pubblicazioni e link utili

La persona responsabile dell'inserimento delle informazioni sullo studio fornisce volontariamente queste pubblicazioni. Questi possono riguardare qualsiasi cosa relativa allo studio.

Pubblicazioni generali

Studiare le date dei record

Queste date tengono traccia dell'avanzamento della registrazione dello studio e dell'invio dei risultati di sintesi a ClinicalTrials.gov. I record degli studi e i risultati riportati vengono esaminati dalla National Library of Medicine (NLM) per assicurarsi che soddisfino specifici standard di controllo della qualità prima di essere pubblicati sul sito Web pubblico.

Studia le date principali

Inizio studio (Stimato)

1 gennaio 2027

Completamento primario (Stimato)

1 dicembre 2029

Completamento dello studio (Stimato)

1 dicembre 2029

Date di iscrizione allo studio

Primo inviato

9 settembre 2026

Primo inviato che soddisfa i criteri di controllo qualità

14 settembre 2026

Primo Inserito (Effettivo)

16 settembre 2026

Aggiornamenti dei record di studio

Ultimo aggiornamento pubblicato (Effettivo)

16 settembre 2026

Ultimo aggiornamento inviato che soddisfa i criteri QC

14 settembre 2026

Ultimo verificato

1 settembre 2026

Maggiori informazioni

Termini relativi a questo studio

Parole chiave

Termini MeSH pertinenti aggiuntivi

Altri numeri di identificazione dello studio

  • CORBERA-R15-SJP-2026

Piano per i dati dei singoli partecipanti (IPD)

Hai intenzione di condividere i dati dei singoli partecipanti (IPD)?

SÌ

Descrizione del piano IPD

De-identified individual participant data will be shared through the NIMH Data Archive (NDA). Shared data will include demographic, behavioral, clinical/phenotypic, and questionnaire data; expectancy ratings and trial-level responses from the Social Judgment Paradigm; raw 64-channel EEG data; and processed EEG derivatives underlying project findings, including ERP and time-frequency measures. Direct identifiers will not be shared.

Periodo di condivisione IPD

Data underlying peer-reviewed publications will be shared by the time of publication. Other study data, including unpublished data, will be shared no later than the end of the period of performance, including any no-cost extensions.

Criteri di accesso alla condivisione IPD

Individual participant data will be available through the NIMH Data Archive (NDA) in accordance with NDA data access policies and procedures. Access to participant-level data will be governed by NDA requirements designed to protect participants' privacy, rights, and confidentiality. Direct identifiers will not be shared.

Informazioni su farmaci e dispositivi, documenti di studio

Studia un prodotto farmaceutico regolamentato dalla FDA degli Stati Uniti

No

Studia un dispositivo regolamentato dalla FDA degli Stati Uniti

No

Queste informazioni sono state recuperate direttamente dal sito web clinicaltrials.gov senza alcuna modifica. In caso di richieste di modifica, rimozione o aggiornamento dei dettagli dello studio, contattare register@clinicaltrials.gov. Non appena verrà implementata una modifica su clinicaltrials.gov, questa verrà aggiornata automaticamente anche sul nostro sito web .

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