Neural Mechanisms of Social Feedback Evaluation in Young Adults Across the Schizotypy Spectrum: An EEG Social Judgment Study
14 de septiembre de 2026 actualizado por: Central Connecticut State University
Neural Mechanisms of Social Feedback Evaluation in Schizotypy: An EEG Study of Oscillatory and Event-Related Potentials
This study will examine how young adults with different levels of schizotypal traits process social acceptance and rejection.
Participants between 18 and 35 years old will complete a single laboratory session that includes questionnaires and electroencephalography (EEG), a noninvasive method that measures electrical brain activity through sensors placed on the scalp.
During EEG recording, participants will complete a computer-based Social Judgment Paradigm (SJP) in which they form expectations about whether another person will like or dislike them and then receive experimentally controlled acceptance or rejection feedback.
The study will examine how brain responses differ when social feedback is expected versus unexpected and whether these responses vary with schizotypal traits.
The goal is to better understand the brain mechanisms involved in evaluating social feedback.
This study does not provide treatment and does not test a drug or medical device.
Descripción general del estudio
Estado
Aún no reclutando
Condiciones
Intervención / Tratamiento
Descripción detallada
Schizotypal traits occur along a continuum in the general population and are associated with differences in social functioning and social information processing. This study will investigate neural responses to social feedback in young adults across the schizotypy spectrum using electroencephalography (EEG).
Participants between 18 and 35 years old will complete a single experimental session. During EEG recording, they will perform a Social Judgment Paradigm (SJP) in which they first form an expectation about whether another person will respond positively or negatively toward them and subsequently receive acceptance or rejection feedback. This produces four within-participant feedback conditions: expected acceptance, expected rejection, unexpected acceptance, and unexpected rejection.
The study will examine brain activity associated with evaluating social feedback, including frontal-midline (FM) theta activity and event-related potentials (ERPs). The primary analyses will test whether neural responses to acceptance and rejection, particularly when feedback violates expectations, vary as a function of continuous schizotypal traits. Participants will also complete self-report measures assessing schizotypal traits, social functioning, and related psychological characteristics.
The study is designed to clarify neural mechanisms involved in social feedback evaluation and to determine how individual differences in schizotypal traits are associated with these processes.
Tipo de estudio
Intervencionista
Inscripción (Estimado)
100
Fase
- No aplica
Contactos y Ubicaciones
Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.
Estudio Contacto
- Nombre: Silvia Corbera LOpez Principal Investigator, PhD.
- Número de teléfono: 860-832-3111
- Correo electrónico: silviac@ccsu.edu
Copia de seguridad de contactos de estudio
- Nombre: Brenda Lopez Grants and Funded Research Administrator
- Número de teléfono: (860) 832-2366
- Correo electrónico: b.lopez@ccsu.edu
Ubicaciones de estudio
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Connecticut
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New Britain, Connecticut, Estados Unidos, 06050
- Central Connecticut State University
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Contacto:
- Silvia Corbera Lopez, Principal Investigator, Ph.D.
- Número de teléfono: 860-832-3111
- Correo electrónico: silviac@ccsu.edu
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Contacto:
- Brenda Lopez Grants and Funded Research Administrator
- Número de teléfono: 860.832.2366
- Correo electrónico: b.lopez@ccsu.edu
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Investigador principal:
- Silvia Corbera Lopez, Ph.D.
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Criterios de participación
Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.
Criterio de elegibilidad
Edades elegibles para estudiar
- Adulto
Acepta Voluntarios Saludables
Sí
Descripción
Inclusion Criteria:
- Ages 18-35 years.
- Able to provide informed consent.
- Able to complete an EEG recording session.
Exclusion Criteria:
- Younger than 18 years or older than 35 years.
- Unable to provide informed consent.
- Unable to complete the EEG recording session.
- No additional exclusion criteria are applied.
Plan de estudios
Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: Ciencia básica
- Asignación: N / A
- Modelo Intervencionista: Asignación de un solo grupo
- Enmascaramiento: Ninguno (etiqueta abierta)
Armas e Intervenciones
Grupo de participantes/brazo |
Intervención / Tratamiento |
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Experimental: Social Judgment Paradigm
Participants complete a single-session Social Judgment Paradigm during EEG recording.
All participants experience four within-subject experimental conditions defined by feedback expectancy (expected versus unexpected) and feedback valence (acceptance versus rejection): expected acceptance, expected rejection, unexpected acceptance, and unexpected rejection.
The order of feedback trials is randomized within the task.
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A computerized Social Judgment Paradigm in which participants receive experimentally controlled social feedback (acceptance/rejection) from purported peers or evaluators while continuous EEG is recorded to assess oscillatory activity and event-related potentials associated with social feedback processing.
Feedback valence and expectancy are manipulated at the trial level, with trial order randomized within the task.
Otros nombres:
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¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
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Frontal Midline Theta Power (4-7 Hz)
Periodo de tiempo: Day 1
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Mean frontal-midline theta-band power (4-7 Hz) derived from EEG data time-locked to feedback onset during the Social Judgment Paradigm, quantified during the prespecified 200-600 ms post-feedback window at frontocentral electrodes.
Theta power will be measured directly across the four feedback conditions defined by expectancy (expected/unexpected) and feedback valence (acceptance/rejection).
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Day 1
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Feedback-Related Negativity (FRN) Amplitude
Periodo de tiempo: Day 1
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Mean event-related potential (ERP) amplitude within the 250-350 ms time window following feedback onset during the Social Judgment Paradigm, quantified at frontocentral electrodes.
FRN amplitude will be measured directly across the four feedback conditions defined by expectancy and feedback valence.
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Day 1
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Late Positive Potential (LPP) Amplitude
Periodo de tiempo: Day 1
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Mean event-related potential (ERP) amplitude within the 350-600 ms time window following feedback onset during the Social Judgment Paradigm, quantified at midline electrodes.
LPP amplitude will be measured directly across the four feedback conditions defined by expectancy and feedback valence.
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Day 1
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Medidas de resultado secundarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
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Behavioral Expectancy Responses
Periodo de tiempo: Day 1
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Participant predictions of social acceptance or rejection during each trial of the Social Judgment Paradigm, including expectancy response and reaction time.
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Day 1
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Schizotypal Personality Questionnaire (SPQ) Total Score
Periodo de tiempo: Day 1
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The Schizotypal Personality Questionnaire (SPQ) is a 74-item self-report measure assessing schizotypal personality traits across cognitive-perceptual, interpersonal, and disorganized dimensions.
Items are answered in a yes/no format and scored dichotomously.
Item scores are summed to produce a total score ranging from 0 to 74.
Higher scores indicate greater levels of schizotypal personality traits.
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Day 1
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Multidimensional Schizotypy Scale (MSS) Scores
Periodo de tiempo: Day 1
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The Multidimensional Schizotypy Scale (MSS) is a 77-item self-report measure assessing positive, negative, and disorganized dimensions of schizotypy.
Items are answered using a true/false response format.
The Positive Schizotypy subscale contains 26 items and ranges from 0 to 26; the Negative Schizotypy subscale contains 26 items and ranges from 0 to 26; and the Disorganized Schizotypy subscale contains 25 items and ranges from 0 to 25.
Higher scores on each subscale indicate greater levels of the corresponding dimension of schizotypy.
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Day 1
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Brief Fear of Negative Evaluation Scale-Revised (BFNES-R) Total Score
Periodo de tiempo: Day 1
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The Brief Fear of Negative Evaluation Scale-Revised (BFNES-R) is a 12-item self-report measure assessing fear of negative evaluation by others.
Each item is rated on a 5-point Likert scale ranging from 0 (not at all characteristic of me) to 4 (extremely characteristic of me).
Item ratings are summed to produce a total score ranging from 0 to 48.
Higher scores indicate greater fear of negative evaluation and greater concern about others' social evaluation.
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Day 1
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Perceived Stress Reactivity Scale (PSRS) Total Score
Periodo de tiempo: Day 1
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The Perceived Stress Reactivity Scale (PSRS) is a 23-item self-report measure assessing an individual's typical response intensity to potentially stressful situations in everyday life.
The scale includes five domains: prolonged reactivity, reactivity to failure, reactivity to social conflict, reactivity to work overload, and reactivity to social evaluation.
Items are scored from 0 to 2, with negatively keyed items reverse-scored, and summed to produce a total score ranging from 0 to 46.
Higher scores indicate greater perceived stress reactivity
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Day 1
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Social Functioning Questionnaire (SFQ) Total Score
Periodo de tiempo: Day 1
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The Social Functioning Questionnaire (SFQ) is an 8-item self-report measure assessing perceived social functioning across domains including work and home activities, finances, close relationships, family relationships, social isolation, sexual functioning, and leisure activities.
Each item is scored from 0 to 3, and item scores are summed to produce a total score ranging from 0 to 24.
Higher scores indicate poorer social functioning.
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Day 1
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Colaboradores e Investigadores
Aquí es donde encontrará personas y organizaciones involucradas en este estudio.
Patrocinador
Publicaciones y enlaces útiles
La persona responsable de ingresar información sobre el estudio proporciona voluntariamente estas publicaciones. Estos pueden ser sobre cualquier cosa relacionada con el estudio.
Publicaciones Generales
- Somerville LH, Heatherton TF, Kelley WM. Anterior cingulate cortex responds differentially to expectancy violation and social rejection. Nat Neurosci. 2006 Aug;9(8):1007-8. doi: 10.1038/nn1728. Epub 2006 Jul 2.
- van der Molen MJW, Dekkers LMS, Westenberg PM, van der Veen FM, van der Molen MW. Why don't you like me? Midfrontal theta power in response to unexpected peer rejection feedback. Neuroimage. 2017 Feb 1;146:474-483. doi: 10.1016/j.neuroimage.2016.08.045. Epub 2016 Aug 23.
- Kortink ED, Weeda WD, Crowley MJ, Gunther Moor B, van der Molen MJW. Community structure analysis of rejection sensitive personality profiles: A common neural response to social evaluative threat? Cogn Affect Behav Neurosci. 2018 Jun;18(3):581-595. doi: 10.3758/s13415-018-0589-1.
Fechas de registro del estudio
Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.
Fechas importantes del estudio
Inicio del estudio (Estimado)
1 de enero de 2027
Finalización primaria (Estimado)
1 de diciembre de 2029
Finalización del estudio (Estimado)
1 de diciembre de 2029
Fechas de registro del estudio
Enviado por primera vez
9 de septiembre de 2026
Primero enviado que cumplió con los criterios de control de calidad
14 de septiembre de 2026
Publicado por primera vez (Actual)
16 de septiembre de 2026
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
16 de septiembre de 2026
Última actualización enviada que cumplió con los criterios de control de calidad
14 de septiembre de 2026
Última verificación
1 de septiembre de 2026
Más información
Términos relacionados con este estudio
Palabras clave
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
- CORBERA-R15-SJP-2026
Plan de datos de participantes individuales (IPD)
¿Planea compartir datos de participantes individuales (IPD)?
SÍ
Descripción del plan IPD
De-identified individual participant data will be shared through the NIMH Data Archive (NDA).
Shared data will include demographic, behavioral, clinical/phenotypic, and questionnaire data; expectancy ratings and trial-level responses from the Social Judgment Paradigm; raw 64-channel EEG data; and processed EEG derivatives underlying project findings, including ERP and time-frequency measures.
Direct identifiers will not be shared.
Marco de tiempo para compartir IPD
Data underlying peer-reviewed publications will be shared by the time of publication.
Other study data, including unpublished data, will be shared no later than the end of the period of performance, including any no-cost extensions.
Criterios de acceso compartido de IPD
Individual participant data will be available through the NIMH Data Archive (NDA) in accordance with NDA data access policies and procedures.
Access to participant-level data will be governed by NDA requirements designed to protect participants' privacy, rights, and confidentiality.
Direct identifiers will not be shared.
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
No
Estudia un producto de dispositivo regulado por la FDA de EE. UU.
No
Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .