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Neural Mechanisms of Social Feedback Evaluation in Young Adults Across the Schizotypy Spectrum: An EEG Social Judgment Study

14. september 2026 opdateret af: Central Connecticut State University

Neural Mechanisms of Social Feedback Evaluation in Schizotypy: An EEG Study of Oscillatory and Event-Related Potentials

This study will examine how young adults with different levels of schizotypal traits process social acceptance and rejection. Participants between 18 and 35 years old will complete a single laboratory session that includes questionnaires and electroencephalography (EEG), a noninvasive method that measures electrical brain activity through sensors placed on the scalp. During EEG recording, participants will complete a computer-based Social Judgment Paradigm (SJP) in which they form expectations about whether another person will like or dislike them and then receive experimentally controlled acceptance or rejection feedback. The study will examine how brain responses differ when social feedback is expected versus unexpected and whether these responses vary with schizotypal traits. The goal is to better understand the brain mechanisms involved in evaluating social feedback. This study does not provide treatment and does not test a drug or medical device.

Studieoversigt

Status

Ikke rekrutterer endnu

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Schizotypal traits occur along a continuum in the general population and are associated with differences in social functioning and social information processing. This study will investigate neural responses to social feedback in young adults across the schizotypy spectrum using electroencephalography (EEG).

Participants between 18 and 35 years old will complete a single experimental session. During EEG recording, they will perform a Social Judgment Paradigm (SJP) in which they first form an expectation about whether another person will respond positively or negatively toward them and subsequently receive acceptance or rejection feedback. This produces four within-participant feedback conditions: expected acceptance, expected rejection, unexpected acceptance, and unexpected rejection.

The study will examine brain activity associated with evaluating social feedback, including frontal-midline (FM) theta activity and event-related potentials (ERPs). The primary analyses will test whether neural responses to acceptance and rejection, particularly when feedback violates expectations, vary as a function of continuous schizotypal traits. Participants will also complete self-report measures assessing schizotypal traits, social functioning, and related psychological characteristics.

The study is designed to clarify neural mechanisms involved in social feedback evaluation and to determine how individual differences in schizotypal traits are associated with these processes.

Undersøgelsestype

Interventionel

Tilmelding (Anslået)

100

Fase

  • Ikke anvendelig

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiekontakt

  • Navn: Silvia Corbera LOpez Principal Investigator, PhD.
  • Telefonnummer: 860-832-3111
  • E-mail: silviac@ccsu.edu

Undersøgelse Kontakt Backup

  • Navn: Brenda Lopez Grants and Funded Research Administrator
  • Telefonnummer: (860) 832-2366
  • E-mail: b.lopez@ccsu.edu

Studiesteder

  • Forenede Stater
    • Connecticut
      • New Britain, Connecticut, Forenede Stater, 06050
        • Central Connecticut State University
        • Kontakt:
          • Silvia Corbera Lopez, Principal Investigator, Ph.D.
          • Telefonnummer: 860-832-3111
          • E-mail: silviac@ccsu.edu
        • Kontakt:
          • Brenda Lopez Grants and Funded Research Administrator
          • Telefonnummer: 860.832.2366
          • E-mail: b.lopez@ccsu.edu
        • Ledende efterforsker:
          • Silvia Corbera Lopez, Ph.D.

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Voksen

Tager imod sunde frivillige

Ja

Beskrivelse

Inclusion Criteria:

  • Ages 18-35 years.
  • Able to provide informed consent.
  • Able to complete an EEG recording session.

Exclusion Criteria:

  • Younger than 18 years or older than 35 years.
  • Unable to provide informed consent.
  • Unable to complete the EEG recording session.
  • No additional exclusion criteria are applied.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Grundvidenskab
  • Tildeling: N/A
  • Interventionel model: Enkelt gruppeopgave
  • Maskning: Ingen (Åben etiket)

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Eksperimentel: Social Judgment Paradigm
Participants complete a single-session Social Judgment Paradigm during EEG recording. All participants experience four within-subject experimental conditions defined by feedback expectancy (expected versus unexpected) and feedback valence (acceptance versus rejection): expected acceptance, expected rejection, unexpected acceptance, and unexpected rejection. The order of feedback trials is randomized within the task.
Adfærdsmæssigt: Social Judgment Paradigm
A computerized Social Judgment Paradigm in which participants receive experimentally controlled social feedback (acceptance/rejection) from purported peers or evaluators while continuous EEG is recorded to assess oscillatory activity and event-related potentials associated with social feedback processing. Feedback valence and expectancy are manipulated at the trial level, with trial order randomized within the task.
Andre navne:
  • SJP

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Frontal Midline Theta Power (4-7 Hz)
Tidsramme: Day 1
Mean frontal-midline theta-band power (4-7 Hz) derived from EEG data time-locked to feedback onset during the Social Judgment Paradigm, quantified during the prespecified 200-600 ms post-feedback window at frontocentral electrodes. Theta power will be measured directly across the four feedback conditions defined by expectancy (expected/unexpected) and feedback valence (acceptance/rejection).
Day 1
Feedback-Related Negativity (FRN) Amplitude
Tidsramme: Day 1
Mean event-related potential (ERP) amplitude within the 250-350 ms time window following feedback onset during the Social Judgment Paradigm, quantified at frontocentral electrodes. FRN amplitude will be measured directly across the four feedback conditions defined by expectancy and feedback valence.
Day 1
Late Positive Potential (LPP) Amplitude
Tidsramme: Day 1
Mean event-related potential (ERP) amplitude within the 350-600 ms time window following feedback onset during the Social Judgment Paradigm, quantified at midline electrodes. LPP amplitude will be measured directly across the four feedback conditions defined by expectancy and feedback valence.
Day 1

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Behavioral Expectancy Responses
Tidsramme: Day 1
Participant predictions of social acceptance or rejection during each trial of the Social Judgment Paradigm, including expectancy response and reaction time.
Day 1
Schizotypal Personality Questionnaire (SPQ) Total Score
Tidsramme: Day 1
The Schizotypal Personality Questionnaire (SPQ) is a 74-item self-report measure assessing schizotypal personality traits across cognitive-perceptual, interpersonal, and disorganized dimensions. Items are answered in a yes/no format and scored dichotomously. Item scores are summed to produce a total score ranging from 0 to 74. Higher scores indicate greater levels of schizotypal personality traits.
Day 1
Multidimensional Schizotypy Scale (MSS) Scores
Tidsramme: Day 1
The Multidimensional Schizotypy Scale (MSS) is a 77-item self-report measure assessing positive, negative, and disorganized dimensions of schizotypy. Items are answered using a true/false response format. The Positive Schizotypy subscale contains 26 items and ranges from 0 to 26; the Negative Schizotypy subscale contains 26 items and ranges from 0 to 26; and the Disorganized Schizotypy subscale contains 25 items and ranges from 0 to 25. Higher scores on each subscale indicate greater levels of the corresponding dimension of schizotypy.
Day 1
Brief Fear of Negative Evaluation Scale-Revised (BFNES-R) Total Score
Tidsramme: Day 1
The Brief Fear of Negative Evaluation Scale-Revised (BFNES-R) is a 12-item self-report measure assessing fear of negative evaluation by others. Each item is rated on a 5-point Likert scale ranging from 0 (not at all characteristic of me) to 4 (extremely characteristic of me). Item ratings are summed to produce a total score ranging from 0 to 48. Higher scores indicate greater fear of negative evaluation and greater concern about others' social evaluation.
Day 1
Perceived Stress Reactivity Scale (PSRS) Total Score
Tidsramme: Day 1
The Perceived Stress Reactivity Scale (PSRS) is a 23-item self-report measure assessing an individual's typical response intensity to potentially stressful situations in everyday life. The scale includes five domains: prolonged reactivity, reactivity to failure, reactivity to social conflict, reactivity to work overload, and reactivity to social evaluation. Items are scored from 0 to 2, with negatively keyed items reverse-scored, and summed to produce a total score ranging from 0 to 46. Higher scores indicate greater perceived stress reactivity
Day 1
Social Functioning Questionnaire (SFQ) Total Score
Tidsramme: Day 1
The Social Functioning Questionnaire (SFQ) is an 8-item self-report measure assessing perceived social functioning across domains including work and home activities, finances, close relationships, family relationships, social isolation, sexual functioning, and leisure activities. Each item is scored from 0 to 3, and item scores are summed to produce a total score ranging from 0 to 24. Higher scores indicate poorer social functioning.
Day 1

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Central Connecticut State University

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Anslået)

1. januar 2027

Primær færdiggørelse (Anslået)

1. december 2029

Studieafslutning (Anslået)

1. december 2029

Datoer for studieregistrering

Først indsendt

9. september 2026

Først indsendt, der opfyldte QC-kriterier

14. september 2026

Først opslået (Faktiske)

16. september 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

16. september 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

14. september 2026

Sidst verificeret

1. september 2026

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • CORBERA-R15-SJP-2026

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

JA

IPD-planbeskrivelse

De-identified individual participant data will be shared through the NIMH Data Archive (NDA). Shared data will include demographic, behavioral, clinical/phenotypic, and questionnaire data; expectancy ratings and trial-level responses from the Social Judgment Paradigm; raw 64-channel EEG data; and processed EEG derivatives underlying project findings, including ERP and time-frequency measures. Direct identifiers will not be shared.

IPD-delingstidsramme

Data underlying peer-reviewed publications will be shared by the time of publication. Other study data, including unpublished data, will be shared no later than the end of the period of performance, including any no-cost extensions.

IPD-delingsadgangskriterier

Individual participant data will be available through the NIMH Data Archive (NDA) in accordance with NDA data access policies and procedures. Access to participant-level data will be governed by NDA requirements designed to protect participants' privacy, rights, and confidentiality. Direct identifiers will not be shared.

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

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