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Uitbreidingsonderzoek naar veiligheid en werkzaamheid op lange termijn voor deelnemers met gevorderde tumoren die momenteel worden behandeld of worden gevolgd in een Pembrolizumab-onderzoek (MK-3475) (MK-3475-587/KEYNOTE-587)

28 oktober 2026 bijgewerkt door: Merck Sharp & Dohme LLC

Een multicenter, open-label, fase III-extensieonderzoek om de veiligheid en werkzaamheid op lange termijn te bestuderen bij deelnemers met gevorderde tumoren die momenteel worden behandeld of worden opgevolgd in een pembrolizumab-onderzoek

The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizumab-based parent studies who transition into this extension study.

This study will consist of three phases: 1) First Course Phase, 2) Survival Follow-up Phase or 3) Second Course Phase. Each participant will transition to this extension study in one of the following three phases, depending on the study phase they were in at the completion of the parent study. Participants who were in the First Course Phase of study treatment with pembrolizumab or lenvatinib in their parent study will enter the First Course Phase of this study and complete up to 35 doses or more every 3 weeks (Q3W) or 17 doses or more every 6 weeks (Q6W) of study treatment with pembrolizumab or a pembrolizumab-based combination or lenvatinib according to arm assignment. Participants who were in the Follow-up Phase in the parent study (post-treatment or Survival Follow-up Phase) will enter the Survival Follow-up Phase of this study. Participants who were in the Second Course Phase in their parent study will enter Second Course Phase of this study and complete up to 17 doses Q3W or 8 doses Q6W of study treatment with pembrolizumab or a pembrolizumab-based combination according to arm assignment.

Any participant originating from a parent trial where crossover to pembrolizumab was permitted upon disease progression may be eligible for 35 doses as Q3W or 17 doses Q6W of pembrolizumab (approximately 2 years), if they progress while on the control arm and pembrolizumab is approved for the indication in the country where the potential eligible crossover participant is being evaluated.

Studie Overzicht

Studietype

Ingrijpend

Inschrijving (Geschat)

3500

Fase

  • Fase 3

Contacten en locaties

In dit gedeelte vindt u de contactgegevens van degenen die het onderzoek uitvoeren en informatie over waar dit onderzoek wordt uitgevoerd.

Studiecontact

Studie Locaties

      • Buenos Aires, Argentinië, C1118AAT
        • Actief, niet wervend
        • Hospital Aleman-Oncology ( Site 1351)
      • Córdoba, Argentinië, X5016KEH
        • Voltooid
        • Hospital Privado Universitario de Córdoba ( Site 1354)
      • Córdoba, Argentinië, X5004SHP
        • Werving
        • Clínica Universitaria Reina Fabiola ( Site 1376)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +5435196778868
      • Córdoba, Argentinië, X5008AAC
        • Werving
        • Centro Medico Privado CEMAIC ( Site 1371)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +5493513976568
      • La Rioja, Argentinië, F5300COE
        • Werving
        • Fundación CORI para la Investigación y Prevención del Cáncer ( Site 1358)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +54-380-443-6443
      • San Juan, Argentinië, J5400EBB
        • Actief, niet wervend
        • Instituto San Marcos ( Site 1366)
      • San Miguel de Tucumán, Argentinië, T4000IAK
        • Actief, niet wervend
        • Centro Medico San Roque-Oncology ( Site 1352)
      • Santiago del Estero, Argentinië, G4200AWD
        • Actief, niet wervend
        • Centro Oncologico Norte. ( Site 1370)
    • Buenos Aires
      • Berazategui, Buenos Aires, Argentinië, B1884BBF
        • Actief, niet wervend
        • Centro de Oncología e Investigación de Buenos Aires ( Site 1357)
      • Buenos Aires., Buenos Aires, Argentinië, C1431FWO
        • Voltooid
        • Centro de Educación Médica e Investigaciones clínicas "Dr. Norberto Quirno" (CEMIC) ( Site 1368)
      • CABA, Buenos Aires, Argentinië, C1426ECQ
        • Werving
        • Derma Internacional SA ( Site 1372)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 01168192023
      • CABA, Buenos Aires, Argentinië, C1093AAS
        • Voltooid
        • Fundacion Favaloro ( Site 1367)
      • Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentinië, C1426ANZ
        • Werving
        • Instituto Alexander Fleming ( Site 1364)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +54-911-36115955
      • Ciudad de Buenos Aires, Buenos Aires, Argentinië, C1012AAR
        • Voltooid
        • IDIM - Instituto de Investigaciones Metabólicas ( Site 1362)
      • Mar del Plata, Buenos Aires, Argentinië, B7600FYZ
        • Werving
        • Instituto de Investigaciones Clínicas Mar del Plata ( Site 1363)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +54-911-36115955
    • Córdoba Province
      • Río Cuarto, Córdoba Province, Argentinië, X5800
        • Werving
        • Instituto Médico Río Cuarto ( Site 1375)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +5493585628491
    • Río Negro Province
      • Viedma, Río Negro Province, Argentinië, R8500ACE
        • Voltooid
        • Clinica Viedma ( Site 1353)
    • Santa Fe Province
      • Rosario, Santa Fe Province, Argentinië, S2000KZE
        • Werving
        • Instituto de Oncologia de Rosario ( Site 1350)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 5493415778394
      • Rosario, Santa Fe Province, Argentinië, S2000DSV
        • Werving
        • Sanatorio Parque ( Site 1355)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 543414268409
      • Rosario, Santa Fe Province, Argentinië, S2000CEJ
        • Actief, niet wervend
        • Fundacion Estudios Clinicos ( Site 1369)
      • Rosario, Santa Fe Province, Argentinië, S2002KDS
        • Actief, niet wervend
        • Hospital Provincial del Centenario ( Site 1359)
    • New South Wales
      • Camperdown, New South Wales, Australië, 2050
        • Voltooid
        • Royal Prince Alfred Hospital-A.W. Morrow Gastroenterology and Liver Centre ( Site 3016)
      • Camperdown, New South Wales, Australië, 2050
        • Actief, niet wervend
        • Chris OBrien Lifehouse ( Site 3003)
      • Liverpool, New South Wales, Australië, 2170
        • Werving
        • Liverpool Hospital-Medical Oncology ( Site 3021)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +61287389000
      • Macquarie University, New South Wales, Australië, 2109
        • Werving
        • Macquarie University ( Site 3010)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +61298123635
      • North Sydney, New South Wales, Australië, 2060
        • Actief, niet wervend
        • Mater Hospital Sydney ( Site 3007)
      • Orange, New South Wales, Australië, 2800
        • Werving
        • Orange Hospital-Clinical Trials Unit ( Site 3027)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 61263693000
      • Port Macquarie, New South Wales, Australië, 2444
        • Werving
        • Port Macquarie - Mid North Coast Cancer Institute-Medical Oncology ( Site 3020)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0439 345 715
      • St Leonards, New South Wales, Australië, 2065
        • Werving
        • Royal North Shore Hospital-Medical Oncology Clinical Trials ( Site 3025)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +61294631172
      • Waratah, New South Wales, Australië, 2298
        • Actief, niet wervend
        • Calvary Mater Newcastle ( Site 3005)
      • Westmead, New South Wales, Australië, 2145
        • Werving
        • Westmead Hospital ( Site 3000)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +61298459553
      • Wollstonecraft, New South Wales, Australië, 2065
        • Werving
        • Melanoma Institute Australia ( Site 3001)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +61299117321
    • Queensland
      • Brisbane, Queensland, Australië, 4101
        • Voltooid
        • Mater Misericordiae Limited-Medical Oncology ( Site 3019)
      • Brisbane, Queensland, Australië, 4120
        • Voltooid
        • Gallipoli Medical Research Ltd ( Site 3011)
      • Herston, Queensland, Australië, 4029
        • Actief, niet wervend
        • Royal Brisbane and Women's Hospital ( Site 3009)
      • Southport, Queensland, Australië, 4215
        • Werving
        • Tasman Oncology Research Pty Ltd ( Site 3012)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +61756132480
      • Southport, Queensland, Australië, 4215
        • Werving
        • Gold Coast University Hospital ( Site 3028)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +611300744284
      • Sunshine Coast, Queensland, Australië, 4575
        • Actief, niet wervend
        • Sunshine Coast University Private Hospital-Coastal Cancer Care ( Site 3032)
      • Townsville, Queensland, Australië, 4814
        • Actief, niet wervend
        • The Townsville Hospital ( Site 3017)
      • Woolloongabba, Queensland, Australië, 4102
        • Actief, niet wervend
        • Princess Alexandra Hospital ( Site 3002)
    • South Australia
      • Adelaide, South Australia, Australië, 5000
        • Werving
        • Royal Adelaide Hospital ( Site 3014)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +61870740000
      • Woodville, South Australia, Australië, 5011
        • Werving
        • The Queen Elizabeth Hospital ( Site 3026)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +61 8 82227096
    • Victoria
      • Clayton, Victoria, Australië, 3168
        • Werving
        • Monash Health ( Site 3015)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +61438780439
      • Heidelberg, Victoria, Australië, 3084
        • Werving
        • Austin Health-Austin Hospital ( Site 3004)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +61385598872
      • Melbourne, Victoria, Australië, 3065
        • Werving
        • St Vincent's Hospital-Oncology Clinical Trials ( Site 3018)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 61392313167
      • Melbourne, Victoria, Australië, 3000
        • Werving
        • Peter MacCallum Cancer Centre-Parkville Cancer Clinical Trials Unit (PCCTU) ( Site 3008)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +61396563642
      • St Albans, Victoria, Australië, 3021
        • Werving
        • Western Health-Sunshine & Footscray Hospitals ( Site 3023)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 61383451333
      • Wendouree, Victoria, Australië, 3355
        • Werving
        • Ballarat Oncology & Haematology Services ( Site 3022)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 61353398000
    • Western Australia
      • Murdock, Western Australia, Australië, 6150
        • Werving
        • Fiona Stanley Hospital ( Site 3029)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 61861526712
      • Nedlands, Western Australia, Australië, 6009
        • Werving
        • Sir Charles Gairdner Hospital ( Site 3006)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +61864573333
      • Subiaco, Western Australia, Australië, 6008
        • Actief, niet wervend
        • St John of God Subiaco Hospital ( Site 3013)
      • Namur, België, 5530
        • Voltooid
        • Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site Godi ( Site 2909)
    • Antwerpen
      • Mechelen, Antwerpen, België, 2800
        • Voltooid
        • AZ Sint-Maarten ( Site 2904)
    • Bruxelles-Capitale, Region de
      • Anderlecht, Bruxelles-Capitale, Region de, België, 1070
        • Voltooid
        • Institut Jules Bordet ( Site 2903)
      • Brussels, Bruxelles-Capitale, Region de, België, 1070
        • Voltooid
        • Cliniques Universitaires de Bruxelles - CUB - Hopital Erasme ( Site 2905)
      • Brussels, Bruxelles-Capitale, Region de, België, 1200
        • Voltooid
        • Cliniques universitaires Saint-Luc-Medical Oncology ( Site 2911)
      • Brussels, Bruxelles-Capitale, Region de, België, 1090
        • Voltooid
        • UZ Brussel ( Site 2900)
    • Oost-Vlaanderen
      • Ghent, Oost-Vlaanderen, België, 9000
        • Voltooid
        • AZ Maria Middelares ( Site 2908)
    • Vlaams-Brabant
      • Leuven, Vlaams-Brabant, België, 3000
        • Voltooid
        • UZ Leuven Gasthuisberg, Gynaecologie-Verloskunde ( Site 2907)
      • Leuven, Vlaams-Brabant, België, 3000
        • Voltooid
        • UZ Leuven ( Site 2901)
      • Leuven, Vlaams-Brabant, België, 3000
        • Voltooid
        • UZ Leuven - Campus Gasthuisberg ( Site 2906)
      • Rio de Janeiro, Brazilië, 22775-001
        • Werving
        • Instituto de de Educação, pesquisa e Gestão em Saúde ( Site 1014)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +552135092115
      • Rio de Janeiro, Brazilië, 20230-130
        • Werving
        • Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA ( Site 1020)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +552132076585
      • São Paulo, Brazilië, 01246-000
        • Werving
        • Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 1001)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +551138932645
      • São Paulo, Brazilië, 01321-001
        • Werving
        • BP - A Beneficencia Portuguesa de São Paulo-Medical Oncology ( Site 1030)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +551135056675
      • São Paulo, Brazilië, 01509-010
        • Werving
        • A. C. Camargo Cancer Center ( Site 1002)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 551121895000
      • São Paulo, Brazilië, 01321-001
        • Werving
        • Hospital Paulistano ( Site 1033)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +551131411083
      • São Paulo, Brazilië, 04014-012
        • Werving
        • Núcleo de Pesquisa Clínica da Rede São Camilo ( Site 1018)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 55 11 4450-0363
    • Ceará
      • Fortaleza, Ceará, Brazilië, 60135-237
        • Werving
        • Hospital São Carlos-Oncocentro Ce ( Site 1029)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +558532865934
      • Fortaleza, Ceará, Brazilië, 60336-232
        • Werving
        • CRIO - CENTRO REGIONAL INTEGRADO DE ONCOLOGIA-Pesquisa Clínica ( Site 1024)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +55 85 32865934
      • Fortaleza, Ceará, Brazilië, 60430235
        • Werving
        • Centro de Pesquisa Clínica do Instituto do Câncer do Ceará ( Site 1016)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +5585999547790
    • Paraná
      • Curitiba, Paraná, Brazilië, 81520-060
        • Actief, niet wervend
        • Hospital Erasto Gaertner ( Site 1036)
    • Rio Grande do Sul
      • Bento Gonçalves, Rio Grande do Sul, Brazilië, 95700-000
        • Werving
        • Hospital Tacchini ( Site 1040)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +555434554333
      • Ijuí, Rio Grande do Sul, Brazilië, 98700-000
        • Werving
        • ONCOSITE - Centro de Pesquisa Clinica em Oncologia ( Site 1008)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +555531950504
      • Passo Fundo, Rio Grande do Sul, Brazilië, 99010-260
        • Werving
        • Hospital de Clínicas de Passo Fundo ( Site 1025)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +555421034130
      • Pelotas, Rio Grande do Sul, Brazilië, 96020-080
        • Werving
        • Lacks - Oncologia E Hematologia ( Site 1026)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +555330285068
      • Porto Alegre, Rio Grande do Sul, Brazilië, 90035-903
        • Werving
        • Hospital de Clinicas de Porto Alegre ( Site 1000)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +555133598619
      • Porto Alegre, Rio Grande do Sul, Brazilië, 90610-000
        • Werving
        • Hospital São Lucas da PUCRS-Centro de Pesquisa em Oncologia ( Site 1006)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 555133203000
      • Porto Alegre, Rio Grande do Sul, Brazilië, 91350-200
        • Werving
        • Hospital Nossa Senhora da Conceição ( Site 1011)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +555135160954
      • Porto Alegree, Rio Grande do Sul, Brazilië, 90050-170
        • Actief, niet wervend
        • Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 1035)
      • Santa Maria, Rio Grande do Sul, Brazilië, 97015-372
        • Werving
        • Clinica Viver ( Site 1021)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +55 55 30267720
      • Ssanta Cruz Do Sul, Rio Grande do Sul, Brazilië, 96810-102
        • Actief, niet wervend
        • Instituto de Oncologia Saint Gallen ( Site 1039)
    • Santa Catarina
      • Florianópolis, Santa Catarina, Brazilië, 88034-000
        • Werving
        • CEPON ( Site 1012)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 5548984320757
      • Florianópolis, Santa Catarina, Brazilië, 88020-210
        • Actief, niet wervend
        • CEPEN - Centro de Pesquisa e Ensino em Oncologia de Santa Catarina ( Site 1034)
      • Itajaí, Santa Catarina, Brazilië, 88301-220
        • Actief, niet wervend
        • Centro de Novos Tratamentos Itajai - Clinica de Neoplasias Litoral ( Site 1041)
    • São Paulo
      • Barretos, São Paulo, Brazilië, 14784400
        • Werving
        • Fundação Pio XII - Hospital de Câncer de Barretos ( Site 1010)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +551733216637
      • Jaú, São Paulo, Brazilië, 17210-080
        • Werving
        • Hospital Amaral Carvalho ( Site 1023)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +551436021397
      • São José do Rio Preto, São Paulo, Brazilië, 15090000
        • Werving
        • Fundação Faculdade Regional de Medicina de São José do Rio Preto-Centro Integrado de Pesquisa ( Site 1003)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 551732015054
      • São Paulo, São Paulo, Brazilië, 01317-001
        • Werving
        • Clínica de Pesquisa e Centro de Estudos em Ginecologia Oncológica e Mamária LTDA ( Site 1017)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 5511991931500
    • Alberta
      • Calgary, Alberta, Canada, T2N 5G2
        • Werving
        • Arthur J.E. Child Comprehensive Cancer Centre ( Site 2815)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: (587) 231-6204
      • Edmonton, Alberta, Canada, T6G 1Z2
        • Werving
        • Cross Cancer Institute ( Site 2804)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 7804328248
    • Manitoba
      • Winnipeg, Manitoba, Canada, R3E 0V9
        • Werving
        • CancerCare Manitoba ( Site 2814)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 204-787-2197
    • Ontario
      • Hamilton, Ontario, Canada, L8V 5C2
        • Voltooid
        • Hamilton Health Sciences-Juravinski Cancer Centre ( Site 2801)
      • Kingston, Ontario, Canada, K7L 2V7
        • Werving
        • Kingston Health Sciences Centre-Kingston General Hospital Site ( Site 2808)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 6135496666
      • London, Ontario, Canada, N6A 5W9
        • Voltooid
        • London Health Sciences Centre ( Site 2806)
      • Ottawa, Ontario, Canada, K1H 8L6
        • Werving
        • The Ottawa Hospital - General Campus ( Site 2813)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 613-737-7700x71985
      • Toronto, Ontario, Canada, M4N 3M5
        • Werving
        • Sunnybrook Research Institute ( Site 2802)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 4164804616
      • Toronto, Ontario, Canada, M5G 1X5
        • Werving
        • Mount Sinai Hospital ( Site 2811)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 416-586-5117
      • Toronto, Ontario, Canada, M5G 2C4
        • Werving
        • Princess Margaret Cancer Centre ( Site 2803)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 4169462000
    • Quebec
      • Greenfield Park, Quebec, Canada, J4V 2H1
        • Werving
        • Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre-Oncology ( Site 2809)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 4504665000
      • Laval, Quebec, Canada, H7M 3L9
        • Werving
        • Centre Intégré de Santé et de Services Sociaux (CISSS) de La-Centre intégré de cancérologie de Lava ( Site 2810)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 450-668-1010x23671
      • Montreal, Quebec, Canada, H2X 3E4
        • Werving
        • Centre Hospitalier de l Universite de Montreal - CHUM ( Site 2807)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 5144127512
      • Montreal, Quebec, Canada, H3T 1E2
        • Werving
        • Jewish General Hospital ( Site 2800)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 5143408222
      • Montreal, Quebec, Canada, H4A 3J1
        • Werving
        • McGill University Health Centre ( Site 2818)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 5149341934
      • Montreal, Quebec, Canada, H3T 1M5
        • Werving
        • St. Marys Hospital Center ( Site 2820)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 514-345-3511x3378
      • Québec, Quebec, Canada, G1J 1Z4
        • Werving
        • Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 2805)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 4185254444
      • Sherbrooke, Quebec, Canada, J1H 5H4
        • Werving
        • Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Univer ( Site 2812)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 8193461110X12848
      • Trois-Rivières, Quebec, Canada, G8Z 3R9
        • Werving
        • Centre integre universitaire de sante et de services sociaux de la Mauricie-et-du-centre-du-quebec ( Site 2816)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 8196973333x63238
      • Antofagasta, Chili, 1263521
        • Werving
        • Bradford Hill Norte ( Site 2761)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56974944605
    • Araucania
      • Temuco, Araucania, Chili, 4800827
        • Werving
        • James Lind Centro de Investigacion del Cancer ( Site 2757)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56956083262
      • Temuco, Araucania, Chili, 4810148
        • Werving
        • CIDO SpA ( Site 2765)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56452657374
    • Biobio
      • Concepción, Biobio, Chili, 4070196
        • Werving
        • Biocenter ( Site 2763)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56412858421
    • Coquimbo Region
      • La Serena, Coquimbo Region, Chili, 1720430
        • Werving
        • IC La Serena Research ( Site 2766)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56958646664
    • Maule Region
      • Talca, Maule Region, Chili, 3465584
        • Werving
        • UNIVERSIDAD CATÓLICA DEL MAULE ( Site 2768)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56712635600
    • Region M. de Santiago
      • Santiago, Region M. de Santiago, Chili, 7500713
        • Voltooid
        • Orlandi Oncologia-Oncology ( Site 2752)
      • Santiago, Region M. de Santiago, Chili, 7500921
        • Werving
        • Fundacion Arturo Lopez Perez FALP ( Site 2750)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56992108354
      • Santiago, Region M. de Santiago, Chili, 7500994
        • Werving
        • Oncovida ( Site 2759)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 56225992945
      • Santiago, Region M. de Santiago, Chili, 8330024
        • Werving
        • Pontificia Universidad Catolica de Chile-Hemato-Oncology ( Site 2751)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56963413803
      • Santiago, Region M. de Santiago, Chili, 8380455
        • Werving
        • Instituto Nacional del Cancer-CR Investigación ( Site 2753)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56 2575 7100
      • Santiago, Region M. de Santiago, Chili, 8420383
        • Werving
        • Bradfordhill-Clinical Area ( Site 2756)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56229490970
      • Santiago, Region M. de Santiago, Chili, 7580206
        • Werving
        • Clínica Inmunocel ( Site 2762)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56997890202
      • Santiago, Region M. de Santiago, Chili, 7500653
        • Werving
        • Centro de Estudios Clínicos SAGA ( Site 2767)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +562223592703
    • Valparaiso
      • Viña del Mar, Valparaiso, Chili, 2540488
        • Werving
        • Centro de Investigaciones ( Site 2755)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56323245375
      • Viña del Mar, Valparaiso, Chili, 2520598
        • Werving
        • ONCOCENTRO APYS-ACEREY ( Site 2758)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +56323320850
    • Anhui
      • Hefei, Anhui, China, 230036
        • Werving
        • Anhui Provincil Hospital South District-Respiratory Medicine Dept ( Site 3487)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 18963789187
      • Hefei, Anhui, China, 230071
        • Werving
        • Anhui Provincial Hospital ( Site 3480)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +8655162283760
    • Beijing Municipality
      • Beijing, Beijing Municipality, China, 100035
        • Werving
        • Beijing Cancer Hospital ( Site 3451)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 010-88121122
      • Beijing, Beijing Municipality, China, 100071
        • Werving
        • The Fifth Medical Center Of The Chinese PLA General Hospital (South) ( Site 3465)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 861066947161
      • Beijing, Beijing Municipality, China, 100142
        • Werving
        • Beijing Cancer Hospital ( Site 3499)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +861088196100
      • Beijing, Beijing Municipality, China, 100142
        • Werving
        • Beijing Cancer Hospital ( Site 3500)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +861088197746
      • Beijing, Beijing Municipality, China, 100142
        • Werving
        • Beijing Cancer hospital-Thoracic Cancer Department A ( Site 3454)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 010-88121122
      • Beijing, Beijing Municipality, China, 100730
        • Werving
        • Chinese Academy of medical science, Peking Union Medical College Hospital(Dongdan) ( Site 3466)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: (010)69158883
    • Chongqing Municipality
      • Chongqing, Chongqing Municipality, China, 400042
        • Werving
        • Army Medical Center of People's Liberation Army-Oncology Department ( Site 3477)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 13908338998
    • Fujian
      • Fuzhou, Fujian, China, 350014
        • Werving
        • Fujian Provincial Cancer Hospital ( Site 3461)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +8659187487329
      • Xiamen, Fujian, China, 361003
        • Werving
        • The First Affiliated Hospital of Xiamen University ( Site 3514)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0592-2139767
    • Guangdong
      • Guanghzou, Guangdong, China, 510515
        • Werving
        • Southern medical university Nangfang Hospital ( Site 3490)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 020-61641888
      • Guangzhou, Guangdong, China, 510030
        • Werving
        • SUN YAT-SEN UNIVERSITY CANCER CENTRE-Internal Medicine ( Site 3452)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +862087343535
      • Guangzhou, Guangdong, China, 510060
        • Werving
        • Sun Yat-sen University Cancer Center-melanoma ( Site 3482)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +8659187487329
      • Guangzhou, Guangdong, China, 510080
        • Werving
        • Guangdong Provincial People's Hospital-Cancer Center ( Site 3462)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +8602083827812
      • Guangzhou, Guangdong, China, 510080
        • Werving
        • The First Affiliated Hospital, Sun Yat-sen University-pneumology department ( Site 3459)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +862087333133
      • Guangzhou, Guangdong, China, 510000
        • Werving
        • The Sixth Affiliated Hospital of Sun Yat-sen University ( Site 3491)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 020 3825 4110
      • Guangzhou, Guangdong, China, 510120
        • Werving
        • The First Affiliated Hospital of Guangzhou Medical University-thoracic surgery department ( Site 3460)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +862083062755
      • Guangzhou, Guangdong, China, 510515
        • Werving
        • Nanfang Hospital of Southern Medical University ( Site 3509)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 020-62786847
    • Guizhou
      • Guiyang, Guizhou, China, 550008
        • Werving
        • The Affiliated Cancer Hospital of Guizhou Medical University ( Site 3498)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0851-86812999
    • Hebei
      • Shijiazhuang, Hebei, China, 050011
        • Actief, niet wervend
        • Fourth Hospital of Hebei Medical University ( Site 3520)
    • Heilongjiang
      • Harbin, Heilongjiang, China, 150081
        • Werving
        • Harbin Medical University Cancer Hospital-Harbin Medical University Cancer Hospital ( Site 3475)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0451-86298000
      • Harbin, Heilongjiang, China, 150081
        • Werving
        • Harbin Medical University Cancer Hospital ( Site 3506)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +8613945095085
    • Henan
      • Zhengzhou, Henan, China, 450008
        • Werving
        • Henan Cancer Hospital ( Site 3488)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0371-65587588
    • Hubei
      • Wuhan, Hubei, China, 430022
        • Werving
        • Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 3492)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 027 8572 6754
      • Wuhan, Hubei, China, 430000
        • Voltooid
        • Tongji Hospital Tongji Medical,Science & Technology-oncology ( Site 3476)
    • Hunan
      • Changsha, Hunan, China, 410013
        • Werving
        • Hunan Cancer Hospital ( Site 3485)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0731-88651900
      • Changsha, Hunan, China, 410008
        • Actief, niet wervend
        • Xiangya Hospital Central South University-Respiratory ( Site 3479)
      • Changsha, Hunan, China, 410008
        • Werving
        • Xiangya Hospital Central South University-Gynecology ( Site 3497)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +86073189753999
      • Changsha, Hunan, China, 410013
        • Werving
        • Hunan Cancer Hospital ( Site 3501)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0731-88651900
      • Changsha, Hunan, China, 410008
        • Werving
        • Xiangya Hospital Central South University ( Site 3508)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0731-89753999
    • Jiangsu
      • Nanjing, Jiangsu, China, 210009
        • Werving
        • Jiangsu Cancer Hospital-Medical Oncotherapy ( Site 3469)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 8613901581264
      • Yancheng, Jiangsu, China, 224005
        • Werving
        • Yancheng First People s Hospital ( Site 3504)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0515-66696800
      • Yangzhou, Jiangsu, China, 225000
        • Werving
        • Northern Jiangsu People's Hospital-General Surgery Department ( Site 3474)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 13813194298
    • Jiangxi
      • Nanchang, Jiangxi, China, 30006
        • Werving
        • The First Affiliated Hospital of Nanchang University ( Site 3513)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0791-88695051
    • Jilin
      • Changchun, Jilin, China, 130021
        • Werving
        • The First Hospital of Jilin University-Oncology ( Site 3464)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0431-88782222
      • Changchun, Jilin, China, 132000
        • Werving
        • Jilin Province Tumor Hospital ( Site 3484)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0431-80596607
    • Shaanxi
      • Xi'an, Shaanxi, China, 710038
        • Werving
        • Tangdu Hospital of Fourth Military Medical University of Chi-department of radiotherapy ( Site 3455)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 029-84777777
    • Shandong
      • Jinan, Shandong, China, 250117
        • Werving
        • Shandong Cancer Hospital ( Site 3517)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +86053167626073
      • Linyi, Shandong, China, 276000
        • Werving
        • LinYi Cancer Hospital ( Site 3511)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0539-8121800
    • Shanghai Municipality
      • Shanghai, Shanghai Municipality, China, 200032
        • Werving
        • Fudan University Shanghai Cancer Center ( Site 3467)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +86 13636382225
      • Shanghai, Shanghai Municipality, China, 200032
        • Werving
        • Zhongshan Hospital of Fudan University ( Site 3503)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 021-64041990
      • Shanghai, Shanghai Municipality, China, 200090
        • Werving
        • Obstetrics & Gynecology Hospital of Fudan University ( Site 3494)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 021-33189900
      • Shanghai, Shanghai Municipality, China, 200433
        • Werving
        • Shanghai Pulmonary Hospital ( Site 3470)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 8613817918714
    • Shanxi
      • XiAn, Shanxi, China, 710061
        • Werving
        • The First Affiliated Hospital of Xi an Jiaotong University ( Site 3489)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 029-58324600
    • Sichuan
      • Chengdu, Sichuan, China, 610041
        • Actief, niet wervend
        • West China Hospital Sichuan University-respiratory ( Site 3473)
      • Chengdu, Sichuan, China, 610213
        • Werving
        • Sichuan Cancer hospital. ( Site 3515)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +862885420305
      • Yibin, Sichuan, China, 644000
        • Werving
        • The Second People's Hospital of Yibin ( Site 3516)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0831-2381106
    • Tianjin Municipality
      • Tianjin, Tianjin Municipality, China, 300060
        • Werving
        • Tianjin Medical University Cancer Institute and Hospital ( Site 3456)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 022-23109106
    • Xinjiang
      • Ürümqi, Xinjiang, China, 830000
        • Werving
        • Xinjiang Medical University Cancer Hospital - Urumqi-galactophore department ( Site 3486)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0991-7968088
      • Ürümqi, Xinjiang, China, 841100
        • Werving
        • The Affiliated Cancer Hospital of Xinjiang Medical University ( Site 3502)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0991-7968088
    • Zhejiang
      • Hangzhou, Zhejiang, China, 310002
        • Werving
        • Hangzhou Cancer Hospital-Medical Oncology ( Site 3468)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 13735430109
      • Hangzhou, Zhejiang, China, 310022
        • Werving
        • Zhejiang Cancer Hospital ( Site 3481)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 13588832760
      • Hangzhou, Zhejiang, China, 310001
        • Werving
        • Women s Hospital School of Medicine Zhejiang University ( Site 3493)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0571-89992071
      • Hangzhou, Zhejiang, China, 310016
        • Werving
        • Sir Run Run Shaw Hospital ( Site 3505)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0571-86090073
      • Hangzhou, Zhejiang, China, 310003
        • Werving
        • The First Affiliated Hospital of Zhejiang University ( Site 3518)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 057187236560
      • Hangzhou, Zhejiang, China, 310022
        • Werving
        • Zhejiang Cancer Hospital ( Site 3495)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +86 13750851650
    • Antioquia
      • Medellín, Antioquia, Colombia, 050030
        • Werving
        • Fundacion Colombiana de Cancerología Clinica Vida ( Site 2707)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +57 3134336816
      • Medellín, Antioquia, Colombia, 050024
        • Werving
        • Promotora Médica Las Américas S.A. ( Site 2702)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 574 3409393 ext 5329
    • Atlántico
      • Barranquilla, Atlántico, Colombia, 080020
        • Werving
        • Clinica de la Costa S.A.S. ( Site 2705)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +57 6053369999x229
    • Bogota D.C.
      • Bogotá, Bogota D.C., Colombia, 110221
        • Werving
        • Administradora Country SA - Clinica del Country ( Site 2701)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +573174236866
    • Cesar Department
      • Valledupar, Cesar Department, Colombia, 200001
        • Werving
        • Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 2704)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 573015371818
    • Cundinamarca
      • Bogota, Cundinamarca, Colombia, 111151
        • Werving
        • Instituto Nacional De Cancerologia-Oncología Clínica ( Site 2706)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +576014320160
    • Departamento de Córdoba
      • Montería, Departamento de Córdoba, Colombia, 230002
        • Werving
        • IMAT S.A.S ( Site 2703)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +573135342052
    • Risaralda Department
      • Pereira, Risaralda Department, Colombia, 660001
        • Werving
        • Oncologos del Occidente ( Site 2709)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +573114746650
    • Valle del Cauca Department
      • Cali, Valle del Cauca Department, Colombia, 760032
        • Werving
        • Fundación Valle del Lili ( Site 2700)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +576023319090Ext7760
      • Cali, Valle del Cauca Department, Colombia, 760042
        • Werving
        • Clínica Imbanaco S.A.S ( Site 2708)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +576023851000
      • San José, Costa Rica, 10103
        • Werving
        • CIMCA ( Site 3900)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +50683893636
    • Provincia de San José
      • Santa Ana, Provincia de San José, Costa Rica, 10903
        • Actief, niet wervend
        • Hospital Metropolitano - Sede Lindora ( Site 3901)
    • Region Syddanmark
      • Odense, Region Syddanmark, Denemarken, 5000
        • Actief, niet wervend
        • Odense Universitetshospital ( Site 0650)
      • Vejle, Region Syddanmark, Denemarken, 7100
        • Werving
        • Vejle Sygehus ( Site 0653)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +45 79405000
      • Berlin, Duitsland, 14165
        • Voltooid
        • Helios Klinikum Emil von Behring Berlin-Zehlendorf-Lungenklinik Heckeshorn ( Site 2418)
      • Berlin, Duitsland, 12203
        • Actief, niet wervend
        • Charite Universitätsmedizin Berlin Campus Benjamin Franklin ( Site 2424)
      • Hamburg, Duitsland, 20249
        • Voltooid
        • Facharztzentrum Eppendorf ( Site 2415)
    • Baden-Wurttemberg
      • Tübingen, Baden-Wurttemberg, Duitsland, 72076
        • Voltooid
        • Universitaetsklinikum Tuebingen ( Site 2405)
    • Bavaria
      • Erlangen, Bavaria, Duitsland, 91054
        • Voltooid
        • Universitätsklinikum Erlangen ( Site 2408)
      • Munich, Bavaria, Duitsland, 80337
        • Voltooid
        • Universitaetsklinik Muenchen ( Site 2406)
    • Hesse
      • Frankfurt am Main, Hesse, Duitsland, 60488
        • Voltooid
        • Krankenhaus Nordwest ( Site 2409)
    • Lower Saxony
      • Buxtehude, Lower Saxony, Duitsland, 21614
        • Voltooid
        • Elbe Klinikum Buxtehude ( Site 2400)
      • Hanover, Lower Saxony, Duitsland, 30625
        • Voltooid
        • Medizinische Hochschule Hannover ( Site 2402)
    • North Rhine-Westphalia
      • Essen, North Rhine-Westphalia, Duitsland, 45147
        • Voltooid
        • Universitaetsklinikum Essen ( Site 2404)
    • Saarland
      • Homburg, Saarland, Duitsland, 66424
        • Voltooid
        • Universitaetsklinikum des Saarlandes-Klinik für Innere Medizin V-Pneumologie, Allergologie, Beatmun ( Site 2411)
    • Saxony
      • Dresden, Saxony, Duitsland, 01307
        • Voltooid
        • Universitatsklinikum Carl Gustav Carus ( Site 2407)
    • Schleswig-Holstein
      • Großhansdorf, Schleswig-Holstein, Duitsland, 22927
        • Voltooid
        • LungenClinic Grosshansdorf GmbH ( Site 2412)
    • Thuringia
      • Gera, Thuringia, Duitsland, 07548
        • Voltooid
        • SRH Wald-Klinikum Gera GmbH ( Site 2403)
    • Tartu
      • Tartu, Tartu, Estland, 50406
        • Actief, niet wervend
        • Tartu University Hospital-Radiotherapy and oncology ( Site 3800)
    • National Capital Region
      • Makati City, National Capital Region, Filippijnen, 1229
        • Werving
        • Makati Medical Center ( Site 1702)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 639178990272
      • Quezon City, National Capital Region, Filippijnen, 1102
        • Werving
        • St. Luke s Medical Center ( Site 1700)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +639175431178
      • Quezon City, National Capital Region, Filippijnen, 1100
        • Voltooid
        • Lung Center of the Philippines ( Site 1705)
    • Pirkanmaa
      • Tampere, Pirkanmaa, Finland, 33520
        • Geschorst
        • Tampere University Hospital [Tampere Finland] ( Site 0600)
    • Southwest Finland
      • Turku, Southwest Finland, Finland, 20520
        • Geschorst
        • Turku University Hospital ( Site 0601)
      • Paris, Frankrijk, 75006
        • Werving
        • Hopital Cochin ( Site 2509)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33158411781
      • Paris, Frankrijk, 75010
        • Werving
        • Hopital Saint Louis ( Site 2510)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33142494949
      • Paris, Frankrijk, 75012
        • Werving
        • CHU Hopital Saint Antoine ( Site 2517)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33171970387
      • Paris, Frankrijk, 75020
        • Werving
        • Hôpital Tenon ( Site 2530)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33156016531
      • Paris, Frankrijk, 75020
        • Werving
        • Groupe Hospitalier Diaconesses Croix Saint Simon ( Site 2545)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33 1 44 74 11 53
    • Alpes-Maritimes
      • Nice, Alpes-Maritimes, Frankrijk, 06200
        • Werving
        • Centre Hospitalier Universitaire de Nice - Hôpital l'Archet-Dermatology Department ( Site 2539)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33492036667
    • Alsace
      • Strasbourg, Alsace, Frankrijk, 67091
        • Werving
        • Nouvel Hôpital Civil (NHC) ( Site 2529)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33369550905
    • Aquitaine
      • Pessac, Aquitaine, Frankrijk, 33600
        • Voltooid
        • CHU Bordeaux Haut-Leveque ( Site 2534)
    • Auvergne
      • Lyon, Auvergne, Frankrijk, 69373
        • Werving
        • Centre Hopitalar Leon-Berard ( Site 2519)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33478782654
    • Auvergne-Rhône-Alpes
      • Pierre-Bénite, Auvergne-Rhône-Alpes, Frankrijk, 69495
        • Werving
        • CH Lyon Sud Hospices Civils de Lyon ( Site 2521)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33478861679
    • Bouches-du-Rhone
      • Marseille, Bouches-du-Rhone, Frankrijk, 13015
        • Werving
        • Hopital Nord ( Site 2516)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33491965901
      • Marseille, Bouches-du-Rhone, Frankrijk, 13385
        • Werving
        • CHU La Timone ( Site 2508)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33491388801
      • Marseille, Bouches-du-Rhone, Frankrijk, 13273
        • Werving
        • Hôpital Privé Clairval ( Site 2549)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33496196234
    • Calvados
      • Caen, Calvados, Frankrijk, 14076
        • Werving
        • Centre Francois Baclesse ( Site 2558)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33231455015
    • Cote-d Or
      • Dijon, Cote-d Or, Frankrijk, 21079
        • Werving
        • Centre Georges François Leclerc-Centre de recherche clinique ( Site 2536)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33380737751
    • Doubs
      • Besançon, Doubs, Frankrijk, 25000
        • Werving
        • CHU-Jean Minjoz ( Site 2550)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33381479999
      • Besançon, Doubs, Frankrijk, 25030
        • Voltooid
        • CHU Jean Minjoz ( Site 2520)
    • Finistere
      • Brest, Finistere, Frankrijk, 29200
        • Werving
        • CHRU Brest - Hopital Cavale Blanche ( Site 2504)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33298223578
    • Gironde
      • Bordeaux, Gironde, Frankrijk, 33076
        • Werving
        • Institut Bergonie ( Site 2502)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33556333333
    • Haute-Garonne
      • Toulouse, Haute-Garonne, Frankrijk, 31059
        • Werving
        • CHU Toulouse - Hopital Rangueil ( Site 2518)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33561322142
      • Toulouse, Haute-Garonne, Frankrijk, 31059
        • Werving
        • Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE ( Site 2560)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33531156191
      • Toulouse, Haute-Garonne, Frankrijk, 31400
        • Actief, niet wervend
        • CHU de Toulouse - Hopital Larrey-service de pneumologie ( Site 2526)
    • Haute-Savoie
      • Epagny Metz Tessy, Haute-Savoie, Frankrijk, 74730
        • Actief, niet wervend
        • Centre Hospitalier Annecy Genevois ( Site 2554)
    • Hauts-de-France
      • Lille, Hauts-de-France, Frankrijk, 59020
        • Werving
        • Centre Oscar Lambret ( Site 2551)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33320295959
    • Hauts-de-Seine
      • Boulogne, Hauts-de-Seine, Frankrijk, 92104
        • Werving
        • Ambroise Pare Hopital ( Site 2503)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33149095673
      • Suresnes, Hauts-de-Seine, Frankrijk, 92150
        • Werving
        • Hôpital Foch ( Site 2543)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33146252078
    • Herault
      • Montpellier, Herault, Frankrijk, 34295
        • Werving
        • CHU Montpellier. ( Site 2556)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33467336933
    • Ille-et-Vilaine
      • Rennes, Ille-et-Vilaine, Frankrijk, 35042
        • Werving
        • Centre Eugène Marquis Rennes - Centre de Lutte Contre le Cancer ( Site 2525)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 33299253196
    • Indre-et-Loire
      • Chambray-lès-Tours, Indre-et-Loire, Frankrijk, 37170
        • Voltooid
        • Hopital Trousseau ( Site 2512)
      • Tours, Indre-et-Loire, Frankrijk, 37044
        • Werving
        • C.H.U. de Tours - Hopital Bretonneau ( Site 2515)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33247474747
    • Loire-Atlantique
      • Saint-Herblain, Loire-Atlantique, Frankrijk, 44800
        • Werving
        • Hôpital Nord Guillaume-et-René-Laennec / CHU de Nantes-lung oncology ( Site 2546)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33240083333
      • Saint-Herblain, Loire-Atlantique, Frankrijk, 44805
        • Werving
        • Institut de Cancérologie de l'Ouest-Oncologie Médicale ( Site 2522)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33240679900
    • Lorraine
      • Vandœuvre-lès-Nancy, Lorraine, Frankrijk, 54519
        • Werving
        • Institut de Cancérologie de Lorraine Alexis Vautrin ( Site 2532)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33383598461
    • Nord
      • Lille, Nord, Frankrijk, 59037
        • Werving
        • CHRU Lille Hospital Claude Huriez ( Site 2506)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33320444193
    • Puy-de-Dome
      • Clermont-Ferrand, Puy-de-Dome, Frankrijk, 63003
        • Werving
        • Centre Jean Perrin - Centre Régional de Lutte contre le Cancer d'Auvergne-ONCOLOGY ( Site 2542)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33473278137
    • Pyrenees-Atlantiques
      • Pau, Pyrenees-Atlantiques, Frankrijk, 64000
        • Werving
        • Centre Hospitalier de Pau ( Site 2563)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33559924723
    • Rhone
      • Pierre-Bénite, Rhone, Frankrijk, 35033
        • Werving
        • C.H.U. Pontchaillou ( Site 2511)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33299289795
    • Sarthe
      • Le Mans, Sarthe, Frankrijk, 72000
        • Werving
        • Centre Hospitalier du Mans-Pneumologie ( Site 2527)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33243432764
    • Seine-Maritime
      • Rouen, Seine-Maritime, Frankrijk, 76038
        • Werving
        • Centre Henri Becquerel ( Site 2547)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33232082222
    • Seine-Saint-Denis
      • Bobigny, Seine-Saint-Denis, Frankrijk, 93000
        • Voltooid
        • Hôpital Avicenne-Dermatologie ( Site 2538)
    • Somme
      • Amiens, Somme, Frankrijk, 80000
        • Werving
        • Clinique de L'Europe ( Site 2548)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33360125235
    • Val-de-Marne
      • Créteil, Val-de-Marne, Frankrijk, 94010
        • Werving
        • HENRI MONDOR HOSPITAL ( Site 2561)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +330149814182
      • Créteil, Val-de-Marne, Frankrijk, 94010
        • Werving
        • Centre Hospitalier Intercommunal de Créteil ( Site 2514)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33157022101
      • Villejuif, Val-de-Marne, Frankrijk, 94800
        • Werving
        • Hôpital Universitaire Paul Brousse ( Site 2541)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33145596540
    • Vaucluse
      • Avignon, Vaucluse, Frankrijk, 84918
        • Werving
        • Institut Sainte Catherine ( Site 2557)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33490276397
    • Vienne
      • Poitiers, Vienne, Frankrijk, 86021
        • Werving
        • Centre Hospitalier Universitaire de Poitiers-Dermatologie ( Site 2544)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0549444444
    • Île-de-France Region
      • Clichy, Île-de-France Region, Frankrijk, 92110
        • Werving
        • Hôpital Beaujon ( Site 2524)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33140875614
      • Paris, Île-de-France Region, Frankrijk, 75014
        • Werving
        • Groupe hospitalier Paris saint Joseph-Service de Pneumologie-Allergologie -Oncologie Thoracique ( Site 2533)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33144123752
      • Villejuif, Île-de-France Region, Frankrijk, 94800
        • Werving
        • Institut Gustave Roussy ( Site 2513)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +33142114210
      • Thessaloniki, Griekenland, 570 01
        • Werving
        • European Interbalkan Medical Center ( Site 1855)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0030 2310400213
    • Attica
      • Athens, Attica, Griekenland, 115 27
        • Werving
        • General Hospital of Athens "Laiko"-Hematology Department ( Site 1851)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0030 2136060981
      • Athens, Attica, Griekenland, 115 27
        • Voltooid
        • Sotiria Regional Chest Diseases Hospital of Athens ( Site 1850)
      • Athens, Attica, Griekenland, 161 21
        • Werving
        • Andreas Syggros Hospital ( Site 1853)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0030 2107210839
      • Guatemala City, Guatemala, 01009
        • Werving
        • MEDI-K ( Site 3403)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +5022291-2323
      • Guatemala City, Guatemala, 01010
        • Werving
        • Oncomedica ( Site 3401)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +50222781269
      • Guatemala City, Guatemala, 01015
        • Werving
        • Grupo Medico Angeles ( Site 3402)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +50223857572
      • Guatemala City, Guatemala, 01010
        • Werving
        • CELAN,S.A ( Site 3405)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +5022783107
      • Budapest, Hongarije, 1088
        • Werving
        • Semmelweis University-Belgyógyászati és Hematológiai Klinika ( Site 1406)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +36202051965
      • Budapest, Hongarije, 1121
        • Werving
        • Orszagos Koranyi Pulmonologiai Intezet ( Site 1403)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +36302005233
      • Budapest, Hongarije, 1145
        • Werving
        • Uzsoki Utcai Kórház-Onkoradiológiai Osztály ( Site 1413)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +36 1 467 3700
      • Debrecen, Hongarije, 4032
        • Werving
        • Debreceni Egyetem Klinikai Kozpont-Onkológiai Klinika ( Site 1412)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +36 52 512 701
      • Debrecen, Hongarije, 4032
        • Werving
        • Debreceni Egyetem Klinikai Kozpont-Belgyógyászati Klinika (Haematologia) ( Site 1415)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +36 52 255 196
      • Kaposvár, Hongarije, 7400
        • Werving
        • Somogy Megyei Kaposi Mor Oktato Korhaz ( Site 1402)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +36304805269
      • Zalaegerszeg, Hongarije, 8900
        • Werving
        • Zala Megyei Szent Rafael Korhaz ( Site 1400)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +3692501527
    • Bekes County
      • Gyula, Bekes County, Hongarije, 5700
        • Werving
        • Békés Megyei Központi Kórház Pándy Kálmán Tagkórház-Megyei Onkológiai Centrum ( Site 1405)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +3666526526
    • Borsod-Abauj Zemplen county
      • Miskolc, Borsod-Abauj Zemplen county, Hongarije, 3526
        • Werving
        • Borsod-Abaúj-Zemplén Megyei Központi Kórház és Egyetemi Oktatókórház ( Site 1409)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +36304719966
    • Bács-Kiskun county
      • Kecskemét, Bács-Kiskun county, Hongarije, 6000
        • Werving
        • Bacs-Kiskun Varmegyei Oktatokorhaz-Onkoradiologiai Kozpont ( Site 1419)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +3676519853
    • Fejér
      • Székesfehérvár, Fejér, Hongarije, 8000
        • Werving
        • Fejér Megyei Szent György Egyetemi Oktató Kórház-l.Pulmonologia ( Site 1407)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +36309513053
    • Győr-Moson-Sopron
      • Győr, Győr-Moson-Sopron, Hongarije, 9024
        • Werving
        • Petz Aladar Egyetemi Oktato Korhaz-Pulmonológia (Dr. Szalai Zsuzsanna) ( Site 1408)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +3696507900
    • Heves County
      • Gyöngyös, Heves County, Hongarije, 3233
        • Werving
        • Mátrai Gyógyintézet ( Site 1417)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +36203929250
    • Jász-Nagykun-Szolnok
      • Szolnok, Jász-Nagykun-Szolnok, Hongarije, 5000
        • Werving
        • Jász-Nagykun-Szolnok Vármegyei Hetényi Géza Kórház ( Site 1401)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +36209323256
    • Pest County
      • Budapest, Pest County, Hongarije, 1122
        • Werving
        • Országos Onkológiai Intézet-Urogenitális Tumorok és Klinikai Farmakológiai Osztály ( Site 1411)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +36122486003162
      • Törökbálint, Pest County, Hongarije, 2045
        • Werving
        • Reformatus Pulmonologiai Centrum ( Site 1418)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +3623511580
    • Vas County
      • Szombathely, Vas County, Hongarije, 9700
        • Werving
        • Markusovszky Egyetemi Oktatokorhaz-Onkológiai Osztály ( Site 1410)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +36204714153
    • Veszprém megye
      • Farkasgyepű, Veszprém megye, Hongarije, 8582
        • Voltooid
        • Farkasgyepui Tudogyogyintezet-Pulmonologia ( Site 1414)
      • Hksar, Hongkong
        • Werving
        • Queen Mary Hospital ( Site 1902)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 8522255435
      • Hksar, Hongkong
        • Voltooid
        • Queen Mary Hospital-Department of Medicine (Respiratory) ( Site 1900)
      • Hong Kong, Hongkong
        • Werving
        • Princess Margaret Hospital ( Site 1903)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +852 2990 1111
      • Dublin, Ierland, Dublin 8
        • Werving
        • St. James s Hospital ( Site 1801)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +35314103000
      • Dublin, Ierland, D24 NR0A
        • Werving
        • Tallaght University Hospital ( Site 1803)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +35314144209
    • Leinster
      • Dublin, Leinster, Ierland, DO7R2DWY
        • Werving
        • Mater Misercordiae University Hospital ( Site 1800)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +353 1 803 2000
      • Afula, Israël, 1834111
        • Werving
        • Emek Medical Center ( Site 2072)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 9724649572
      • Haifa, Israël, 3109601
        • Werving
        • Rambam Health Care Campus-Oncology Division ( Site 2053)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +97247773811
      • Haifa, Israël, 3339419
        • Voltooid
        • Bnai Zion Medical Center ( Site 2060)
      • Jerusalem, Israël, 9103102
        • Werving
        • Shaare Zedek Medical Center ( Site 2068)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +97226555999
      • Jerusalem, Israël, 9112001
        • Actief, niet wervend
        • Hadassah Ein Kerem Medical Center ( Site 2051)
      • Petah Tikva, Israël, 49100
        • Werving
        • Rabin Medical Center ( Site 2059)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +97239378076
      • Ramat Gan, Israël, 5262000
        • Werving
        • Chaim Sheba Medical Center ( Site 2055)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +97235307096
      • Ramat Gan, Israël, 5265601
        • Voltooid
        • Sheba Medical Center ( Site 2062)
      • Ramat Gan, Israël, 5265601
        • Actief, niet wervend
        • Sheba Medical Center ( Site 2065)
      • Ramat Gan, Israël, 5224213
        • Actief, niet wervend
        • Chaim Sheba Medical Center. ( Site 2052)
      • Safed, Israël, 1311001
        • Voltooid
        • ZIV Medical Center-Hematology Institute ( Site 2061)
      • Tel Aviv, Israël, 6423906
        • Werving
        • Sourasky Medical Center ( Site 2054)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +97236973082
      • Tsrifin, Israël, 6093000
        • Voltooid
        • Shamir Medical Center Assaf Harofeh ( Site 2058)
      • Bergamo, Italië, 24125
        • Voltooid
        • Humanitas Gavazzeni ( Site 1954)
      • Bergamo, Italië, 24127
        • Actief, niet wervend
        • Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII-UOC Oncologia ( Site 1967)
      • Brescia, Italië, 25123
        • Voltooid
        • Azienda Ospedaliera Spedali Civili di Brescia-Oncology ( Site 1972)
      • Genova, Italië, 16132
        • Voltooid
        • IRCCS A.O.U. San Martino - IST ( Site 1961)
      • Milan, Italië, 20132
        • Werving
        • Ospedale San Raffaele. ( Site 1979)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 02 26438003
      • Milan, Italië, 20141
        • Werving
        • Istituto Europeo di Oncologia ( Site 1952)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +390294372161
      • Naples, Italië, 80131
        • Actief, niet wervend
        • Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 1955)
      • Parma, Italië, 43126
        • Werving
        • Azienda Ospedaliero Universitaria di Parma-UO Oncologia Medica ( Site 1964)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 390521702682
      • Pavia, Italië, 27100
        • Werving
        • Fondazione IRCCS Policlinico San Matteo ( Site 1982)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0382.502511
      • Roma, Italië, 00168
        • Werving
        • Policlinico Universitario Agostino Gemelli ( Site 1965)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +390630155878
      • Roma, Italië, 00152
        • Voltooid
        • Azienda Ospedaliera San Camillo Forlanini ( Site 1958)
      • Siena, Italië, 53100
        • Werving
        • ospedale le scotte-U.O.C. Immunoterapia Oncologica ( Site 1969)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +390577586335
      • Terni, Italië, 05100
        • Werving
        • Azienda Ospedaliera Santa Maria ( Site 1962)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +390744205410
      • Torino, Italië, 10126
        • Voltooid
        • Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino ( Site 1974)
    • Emilia-Romagna
      • Bologna, Emilia-Romagna, Italië, 40138
        • Actief, niet wervend
        • IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola ( Site 1978)
    • Lazio
      • Rome, Lazio, Italië, 00144
        • Werving
        • Istittuto Nazionale dei Tumori Regina Elena IRCCS - IFO ( Site 1963)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +390652665637
      • Rome, Lazio, Italië, 00168
        • Werving
        • Fondazione Policlinico Universitario Agostino Gemelli IRCCS -Medical Oncology ( Site 1975)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +39 06 3015 5202
    • Lombardy
      • Milan, Lombardy, Italië, 20133
        • Werving
        • Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1977)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0223903650
      • Monza, Lombardy, Italië, 20900
        • Actief, niet wervend
        • Azienda Ospedaliera San Gerardo ( Site 1980)
    • Milano
      • Rozzano, Milano, Italië, 20089
        • Werving
        • Humanitas-U.O di Oncologia medica ed Ematologia ( Site 1968)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 390282244080
    • Pordenone
      • Aviano, Pordenone, Italië, 33081
        • Voltooid
        • IRCCS CRO Aviano, Hematology/Oncology ( Site 1957)
    • Sicily
      • Catania, Sicily, Italië, 95126
        • Voltooid
        • Ospedale Cannizzaro ( Site 1981)
    • Torino
      • Candiolo, Torino, Italië, 10060
        • Actief, niet wervend
        • INOC - Istituto Nazionale Oncologico Candiolo ( Site 1960)
      • Orbassano, Torino, Italië, 10143
        • Actief, niet wervend
        • Ospedale San Luigi Gonzaga ( Site 1956)
    • Umbria
      • Perugia, Umbria, Italië, 06132
        • Voltooid
        • AO Santa Maria della Misericordia-Oncology Department ( Site 1971)
    • Veneto
      • Padova, Veneto, Italië, 35128
        • Werving
        • Istituto Oncologico Veneto IRCCS ( Site 1976)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +39 049 8215931
      • Chiba, Japan, 260-8717
        • Voltooid
        • Chiba Cancer Center ( Site 3117)
      • Fukuoka, Japan, 810-8563
        • Voltooid
        • National Hospital Organization Kyushu Medical Center ( Site 3136)
      • Fukuoka, Japan, 811-1395
        • Voltooid
        • National Hospital Organization Kyushu Cancer Center ( Site 3169)
      • Fukuoka, Japan, 812-8582
        • Voltooid
        • Kyushu University Hospital ( Site 3143)
      • Fukuoka, Japan, 812-8582
        • Voltooid
        • Kyushu University Hospital ( Site 3185)
      • Gifu, Japan, 501-1112
        • Voltooid
        • Gifu University Hospital ( Site 3161)
      • Hiroshima, Japan, 730-8518
        • Voltooid
        • Hiroshima City Hiroshima Citizens Hospital ( Site 3119)
      • Hiroshima, Japan, 734-8551
        • Voltooid
        • Hiroshima University Hospital ( Site 3154)
      • Kochi, Japan, 781-8555
        • Voltooid
        • Kochi Health Sciences Center ( Site 3145)
      • Kumamoto, Japan, 860-8556
        • Voltooid
        • Kumamoto University Hospital ( Site 3179)
      • Kyoto, Japan, 606-8507
        • Voltooid
        • Kyoto University Hospital ( Site 3181)
      • Niigata, Japan, 951-8520
        • Werving
        • Niigata University Medical & Dental Hospital ( Site 3174)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81252236161
      • Okayama, Japan, 700-8558
        • Werving
        • Okayama University Hospital ( Site 3107)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-86-223-7151
      • Osaka, Japan, 540-0006
        • Werving
        • National Hospital Organization Osaka National Hospital ( Site 3162)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81669421331
      • Osaka, Japan, 541-8567
        • Werving
        • Osaka Prefectural Hospital Organization Osaka International Cancer Institute ( Site 3129)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81669451181
      • Osaka, Japan, 534-0021
        • Voltooid
        • Osaka City General Hospital ( Site 3125)
      • Osaka, Japan, 558-8558
        • Voltooid
        • Osaka General Medical Center ( Site 3184)
      • Tokyo, Japan, 113-8677
        • Werving
        • Tokyo Metropolitan Komagome Hospital ( Site 3133)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-3-3823-2101
      • Tokyo, Japan, 173-8606
        • Voltooid
        • Teikyo University Hospital ( Site 3104)
      • Tokyo, Japan, 135-8550
        • Werving
        • Cancer Institute Hospital of JFCR ( Site 3108)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81335200111
      • Tokyo, Japan, 104-8560
        • Voltooid
        • St.Luke's International Hospital ( Site 3120)
      • Tokyo, Japan, 113-8603
        • Voltooid
        • Nippon Medical School Hospital ( Site 3139)
      • Tokyo, Japan, 104-0045
        • Actief, niet wervend
        • National Cancer Center Hospital ( Site 3130)
      • Tokyo, Japan, 105-8471
        • Actief, niet wervend
        • The Jikei University Hospital ( Site 3156)
      • Tokyo, Japan, 160-8582
        • Actief, niet wervend
        • Keio University Hospital ( Site 3127)
      • Toyama, Japan, 930-8550
        • Voltooid
        • Toyama Prefectural Central Hospital ( Site 3183)
      • Wakayama, Japan, 641-8510
        • Werving
        • Wakayama Medical University Hospital ( Site 3124)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-73-447-2300
    • Aichi-ken
      • Nagoya, Aichi-ken, Japan, 460-0001
        • Werving
        • National Hospital Organization Nagoya Medical Center ( Site 3109)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-52-951-1111
      • Nagoya, Aichi-ken, Japan, 464-8681
        • Werving
        • Aichi Cancer Center ( Site 3101)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81527626111
      • Nagoya, Aichi-ken, Japan, 466-8560
        • Werving
        • Nagoya University Hospital ( Site 3151)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-52-741-2111
    • Chiba
      • Kashiwa, Chiba, Japan, 2778577
        • Werving
        • National Cancer Center Hospital East ( Site 3121)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-4-7133-1111
    • Ehime
      • Matsuyama, Ehime, Japan, 791-0280
        • Voltooid
        • National Hospital Organization Shikoku Cancer Center ( Site 3116)
      • Tōon, Ehime, Japan, 791-0295
        • Werving
        • Ehime University Hospital ( Site 3158)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-89-960-5910
    • Fukuoka
      • Kurume, Fukuoka, Japan, 830-0011
        • Werving
        • Kurume University Hospital ( Site 3105)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81942353311
    • Hokkaido
      • Sapporo, Hokkaido, Japan, 060-8543
        • Werving
        • Sapporo Medical University Hospital ( Site 3113)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-11-611-2111
      • Sapporo, Hokkaido, Japan, 003-0804
        • Voltooid
        • National Hospital Organization Hokkaido Cancer Center ( Site 3160)
      • Sapporo, Hokkaido, Japan, 060-0033
        • Voltooid
        • Sapporo Kosei General Hospital ( Site 3172)
      • Sapporo, Hokkaido, Japan, 060-8648
        • Voltooid
        • Hokkaido University Hospital ( Site 3165)
    • Hyōgo
      • Akashi, Hyōgo, Japan, 673-8558
        • Werving
        • Hyogo Cancer Center ( Site 3131)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-78-929-1151
      • Himeji, Hyōgo, Japan, 670-8520
        • Actief, niet wervend
        • National Hospital Organization Himeji Medical Center ( Site 3111)
      • Kobe, Hyōgo, Japan, 650-0047
        • Voltooid
        • Kobe City Medical Center General Hospital ( Site 3144)
      • Nishinomiya, Hyōgo, Japan, 663-8501
        • Werving
        • Hyogo Medical University Hospital ( Site 3100)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81798456111
    • Ibaraki
      • Kasama, Ibaraki, Japan, 309-1793
        • Werving
        • Ibaraki Prefectural Central Hospital ( Site 3180)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-296-78-0021
      • Tsukuba, Ibaraki, Japan, 305-8576
        • Werving
        • University of Tsukuba Hospital ( Site 3176)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-29-853-3900
    • Ishikawa-ken
      • Kanazawa, Ishikawa-ken, Japan, 920-8641
        • Werving
        • Kanazawa University Hospital ( Site 3140)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-76-265-2000
    • Iwate
      • Shiwa-gun, Iwate, Japan, 028-3695
        • Voltooid
        • Iwate Medical University Hospital ( Site 3157)
    • Kagawa-ken
      • Kita, Kagawa-ken, Japan, 761-0701
        • Voltooid
        • Kagawa University Hospital ( Site 3171)
    • Kanagawa
      • Kawasaki, Kanagawa, Japan, 216-8511
        • Voltooid
        • St. Marianna University Hospital ( Site 3182)
      • Kawasaki, Kanagawa, Japan, 211-8533
        • Actief, niet wervend
        • Nippon Medical School Musashi Kosugi Hospital ( Site 3178)
      • Sagamihara, Kanagawa, Japan, 252-0375
        • Voltooid
        • Kitasato University Hospital ( Site 3142)
      • Yokohama, Kanagawa, Japan, 236-0004
        • Voltooid
        • Yokohama City University Hospital ( Site 3163)
      • Yokohama, Kanagawa, Japan, 241-8515
        • Actief, niet wervend
        • Kanagawa Cancer Center ( Site 3137)
      • Yokosuka, Kanagawa, Japan, 238-8558
        • Voltooid
        • Yokosuka Kyosai Hospital ( Site 3150)
    • Miyagi
      • Natori-shi, Miyagi, Japan, 981-1293
        • Voltooid
        • Miyagi Cancer Center ( Site 3122)
      • Sendai, Miyagi, Japan, 980-8574
        • Werving
        • Tohoku University Hospital ( Site 3175)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-22-717-7000
      • Sendai, Miyagi, Japan, 981-0914
        • Actief, niet wervend
        • Sendai Kousei Hospital ( Site 3115)
    • Nara
      • Kashihara, Nara, Japan, 634-8522
        • Voltooid
        • Nara Medical University Hospital ( Site 3110)
    • Niigata
      • Niigata, Niigata, Japan, 951-8566
        • Voltooid
        • Niigata Cancer Center Hospital ( Site 3173)
    • Okayama-ken
      • Kurashiki, Okayama-ken, Japan, 710-8602
        • Voltooid
        • Kurashiki Central Hospital ( Site 3132)
    • Okinawa
      • Ginowan, Okinawa, Japan, 901-2725
        • Actief, niet wervend
        • University of the Ryukyus Hospital ( Site 3155)
    • Osaka
      • Habikino, Osaka, Japan, 583-8588
        • Voltooid
        • Osaka Habikino Medical Center ( Site 3138)
      • Hirakata, Osaka, Japan, 573-1191
        • Werving
        • Kansai Medical University Hospital ( Site 3126)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-72-804-0101
      • Sakai, Osaka, Japan, 591-8025
        • Werving
        • Osaka Rosai Hospital ( Site 3148)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-72-252-3561
      • Sakai, Osaka, Japan, 590-0197
        • Werving
        • Kindai University Hospital ( Site 3102)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81723660221
      • Sakai, Osaka, Japan, 590-0197
        • Voltooid
        • Kindai University Hospital ( Site 3166)
      • Sakai, Osaka, Japan, 590-0197
        • Voltooid
        • Kindai University Hospital ( Site 3135)
      • Suita, Osaka, Japan, 565-0871
        • Voltooid
        • The University of Osaka Hospital ( Site 3168)
      • Takatsuki, Osaka, Japan, 569-8686
        • Werving
        • Osaka Medical and Pharmaceutical University Hospital ( Site 3187)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-72-683-1221
      • Takatsuki, Osaka, Japan, 569-8686
        • Voltooid
        • Osaka Medical and Pharmaceutical University Hospital ( Site 3167)
    • Saitama
      • Hidaka, Saitama, Japan, 350-1298
        • Werving
        • Saitama Medical University International Medical Center ( Site 3118)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-42-984-4111
      • Kitaadachi-gun, Saitama, Japan, 362-0806
        • Werving
        • Saitama Prefectural Cancer Center ( Site 3112)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-48-722-1111
      • Koshigaya, Saitama, Japan, 3438555
        • Voltooid
        • Dokkyo Medical University Saitama Medical Center ( Site 3152)
      • Tokorozawa, Saitama, Japan, 359-8513
        • Werving
        • National Defense Medical College Hospital ( Site 3177)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-4-2995-1682
    • Shizuoka
      • Nakatogari, Shizuoka, Japan, 411-8777
        • Werving
        • Shizuoka Cancer Center ( Site 3128)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-55-989-5222
    • Tochigi
      • Shimotsuke, Tochigi, Japan, 329-0498
        • Voltooid
        • Jichi Medical University Hospital ( Site 3141)
    • Tokyo
      • Bunkyō, Tokyo, Japan, 113-8519
        • Voltooid
        • Institute of Science Tokyo Hospital ( Site 3149)
      • Koto, Tokyo, Japan, 135-8550
        • Werving
        • Cancer Institute Hospital of JFCR ( Site 3146)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-3-3520-0111
      • Koto, Tokyo, Japan, 135-8550
        • Werving
        • Cancer Institute Hospital of JFCR ( Site 3164)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-3-3520-0111
      • Minato, Tokyo, Japan, 105-8470
        • Werving
        • Toranomon Hospital ( Site 3189)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-3-3588-1111
      • Minato-ku, Tokyo, Japan, 105-8470
        • Voltooid
        • Toranomon Hospital ( Site 3153)
      • Minato-ku, Tokyo, Japan, 105-8470
        • Werving
        • Toranomon Hospital ( Site 3134)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-3-3588-1111
      • Mitaka, Tokyo, Japan, 181-8611
        • Werving
        • Kyorin University Hospital ( Site 3103)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81422475511
      • Mitaka-shi, Tokyo, Japan, 181-8611
        • Voltooid
        • Kyorin University Hospital ( Site 3147)
      • Shinagawa, Tokyo, Japan, 142-8666
        • Werving
        • Showa Medical University Hospital ( Site 3188)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +81-3-3784-8000
      • Shinjuku-ku, Tokyo, Japan, 160-0023
        • Voltooid
        • Tokyo Medical University Hospital ( Site 3170)
    • Yamaguchi
      • Ube, Yamaguchi, Japan, 755-0241
        • Voltooid
        • National Hospital Organization Yamaguchi Ube Medical Center ( Site 3123)
      • Ube, Yamaguchi, Japan, 755-8505
        • Voltooid
        • Yamaguchi University Hospital ( Site 3114)
      • Liepāja, Letland, LV-3414
        • Werving
        • Liepjas reionl slimnca ( Site 3851)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +371 26351999
      • Riga, Letland, LV1079
        • Werving
        • RIGA EAST UNIVERSITY HOSPITAL ,Oncology Centre of Latvia-Out-patient and Day patient facility of Ch ( Site 3850)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +37126594570
      • Vilnius, Litouwen, 08460
        • Werving
        • Vilniaus Universiteto Ligonine Santaros Klinikos ( Site 3300)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +37068388052
      • Vilnius, Litouwen, LT-08406
        • Werving
        • Vilnius University Hospital Santaros Clinics Affiliate - National Cancer Center ( Site 3301)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +37061129056
    • Klaipedos Miestas
      • Klaipėda, Klaipedos Miestas, Litouwen, 92288
        • Voltooid
        • Klaipeda University Hospital-Oncology chemotherapy ( Site 3302)
      • Kuala Lumpur, Maleisië, 59100
        • Werving
        • University Malaya Medical Centre ( Site 0626)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +60379492120
      • Kuala Lumpur, Maleisië, 59100
        • Voltooid
        • Pantai Hospital Kuala Lumpur ( Site 0628)
    • Pahang
      • Kuantan, Pahang, Maleisië, 25100
        • Werving
        • Hospital Tengku Ampuan Afzan ( Site 0627)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +6095706400
    • Pulau Pinang
      • George Town, Pulau Pinang, Maleisië, 10050
        • Werving
        • Gleneagles Penang ( Site 0625)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +6042229189
      • George Town, Pulau Pinang, Maleisië, 10990
        • Werving
        • Hospital Pulau Pinang ( Site 0629)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +6042225333
    • Putrajaya
      • Putrajaya - Wilayah Persekutuan, Putrajaya, Maleisië, 62250
        • Werving
        • Institut Kanser Negara - National Cancer Institute ( Site 0630)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +60123304499
      • Chihuahua City, Mexico, 31123
        • Werving
        • Unidad de Mastologia Avanzada de Chihuahua S.A de C.V ( Site 1109)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 52 6143458712
      • Mexico City, Mexico, 03810
        • Voltooid
        • Oncare Viaducto Napoles ( Site 1107)
      • Querétaro, Mexico, 76000
        • Actief, niet wervend
        • Cuidados Oncologicos. ( Site 1118)
    • Baja California Sur
      • La Paz, Baja California Sur, Mexico, 23040
        • Werving
        • Investigación Oncofarmacéutica-Investigación clínica ( Site 1114)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 52 6121297171
    • Jalisco
      • Guadalajara, Jalisco, Mexico, 44630
        • Werving
        • Centro de Inmuno Oncología de Occidente SA de CV ( Site 1115)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +523332592394
    • Mexico City
      • Mexico City, Mexico City, Mexico, 06700
        • Actief, niet wervend
        • Arke Estudios Clinicos ( Site 1117)
      • Mexico City, Mexico City, Mexico, 14080
        • Actief, niet wervend
        • INSTITUTO NACIONAL DE CANCEROLOGIA ( Site 1102)
    • Nuevo León
      • Monterrey, Nuevo León, Mexico, 66460
        • Werving
        • Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Hematologia and Oncologia ( Site 1113)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 52 8183338111
      • Monterrey, Nuevo León, Mexico, 64710
        • Actief, niet wervend
        • I Can Oncology Center SA de CV ( Site 1116)
      • Monterrey, Nuevo León, Mexico, 64623
        • Actief, niet wervend
        • Avix Investigación Clinica, S.C.-Oncology ( Site 1104)
      • San Pedro Garza García, Nuevo León, Mexico, 66269
        • Actief, niet wervend
        • Centro de Urologa Avanzada del Noreste ( Site 1110)
    • Oaxaca
      • Oaxaca City, Oaxaca, Mexico, 68000
        • Werving
        • Oaxaca Site Management Organization ( Site 1106)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +52 951 229-0849
    • Tamaulipas
      • Ciudad Madero, Tamaulipas, Mexico, 89440
        • Werving
        • Centro de Estudios de Investigacion Metabolicos y Cardiovasculares, S.C. ( Site 1119)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +528331260055
    • Yucatán
      • Mérida, Yucatán, Mexico, 97070
        • Voltooid
        • Medical Care and Research SA de CV ( Site 1103)
      • Groningen, Nederland, 9713GZ
        • Werving
        • Universitair Medisch Centrum Groningen ( Site 1550)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +31503616161
    • Gelderland
      • Nijmegen, Gelderland, Nederland, 6525 GA
        • Werving
        • Radboud University Medical Center ( Site 1554)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +31243610353
    • North Holland
      • Amsterdam, North Holland, Nederland, 1066 CX
        • Werving
        • Antoni van Leeuwenhoek Ziekenhuis ( Site 1551)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +31205129111
      • Amsterdam, North Holland, Nederland, 1081 HV
        • Werving
        • Amsterdam UMC, locatie VUmc ( Site 1555)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +310204444321
    • South Holland
      • Rotterdam, South Holland, Nederland, 3015 GD
        • Voltooid
        • Erasmus MC ( Site 1553)
      • Auckland, Nieuw-Zeeland, 1023
        • Werving
        • Auckland City Hospital ( Site 1503)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +6493670000
      • Wellington, Nieuw-Zeeland, 6021
        • Werving
        • Capital & Coast District Health Board - Wellington Hospital ( Site 1501)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +6449186109
    • Canterbury
      • Christchurch, Canterbury, Nieuw-Zeeland, 8011
        • Actief, niet wervend
        • Canterbury Regional Cancer & Blood Service ( Site 1500)
    • Manawatu-Wanganui
      • Palmerston North, Manawatu-Wanganui, Nieuw-Zeeland, 4442
        • Werving
        • Palmerston North Hospital, MidCentral DHB ( Site 1504)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +6463507486
    • Waikato Region
      • Hamilton, Waikato Region, Nieuw-Zeeland, 3204
        • Actief, niet wervend
        • Waikato Hospital ( Site 1502)
      • Oslo, Noorwegen, 0379
        • Werving
        • Oslo Universitetssykehus Radiumhospitalet ( Site 1450)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +4722934809
      • Oslo, Noorwegen, 0379
        • Werving
        • Oslo universitetssykehus, Radiumhospitalet ( Site 1452)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +47 23026600
    • Vestfold
      • Bergen, Vestfold, Noorwegen, 5021
        • Werving
        • Helse Bergen Haukeland universitetssykehus ( Site 1451)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +4755974200
    • Cherkasy Oblast
      • Cherkasy, Cherkasy Oblast, Oekraïne, 18009
        • Actief, niet wervend
        • COMMUNAL NONPROFIT ENTERPRISE CLINICAL CENTER OF ONCOLOGY, HEMATOLOGY, TRANSPLANTOLOGY AND PALLIATI ( Site 3671)
    • Dnipropetrovsk Oblast
      • Dnipro, Dnipropetrovsk Oblast, Oekraïne, 49102
        • Actief, niet wervend
        • Municipal Non-profit Enterprise "City Clinical Hospital #4" of Dnipro City Council ( Site 3650)
      • Dnipro, Dnipropetrovsk Oblast, Oekraïne, 49005
        • Actief, niet wervend
        • ME І.І. Mechnykov Dnipro Regional Clinical Hospital ( Site 3668)
      • Kryvyi Rih, Dnipropetrovsk Oblast, Oekraïne, 50048
        • Actief, niet wervend
        • MI Kryvyi Rih Oncology Dispensary of Dnipropetrovsk Regional-Chemotherapy department ( Site 3657)
    • Ivano-Frankivsk Oblast
      • Ivano-Frankivsk, Ivano-Frankivsk Oblast, Oekraïne, 76018
        • Werving
        • Communal Non-Commercial Enterprise "Prykarpatski Clinical Oncological Center" of Ivano-Frankivsk Reg ( Site 3663)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +380502094000
    • Kharkiv Oblast
      • Kharkiv, Kharkiv Oblast, Oekraïne, 61070
        • Actief, niet wervend
        • MNPE Regional Center of Oncology ( Site 3665)
      • Kharlkiv, Kharkiv Oblast, Oekraïne, 61024
        • Actief, niet wervend
        • SO"Grigoriev Inst for Med Radiolgy and Oncology of NAMS of Ukraine" ( Site 3666)
    • Khmelnytskyi Oblast
      • Khmelnytskyi, Khmelnytskyi Oblast, Oekraïne, 29009
        • Actief, niet wervend
        • MNE "Khmelnytskyi regional antitumor center" ( Site 3675)
    • Kirovohrad Oblast
      • Kropyvnytskyi, Kirovohrad Oblast, Oekraïne, 25006
        • Voltooid
        • Private Enterprise Private Manufacturing Company Acinus-Medical and Diagnostic Centre ( Site 3656)
    • Kyivska Oblast
      • Khodosovka, Kyivska Oblast, Oekraïne, 08173
        • Werving
        • Asklepion Medical Center ( Site 3667)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0503481865
      • Kyiv, Kyivska Oblast, Oekraïne, 03115
        • Voltooid
        • Municipal non-profit enterprise "Kyiv City Clinical Oncology Center" of executive body of Kyiv City ( Site 3651)
      • Kyiv, Kyivska Oblast, Oekraïne, 03039
        • Actief, niet wervend
        • LLC Clinic Verum Expert ( Site 3669)
      • Kyiv, Kyivska Oblast, Oekraïne, 03022
        • Actief, niet wervend
        • National Cancer Institute-Department of Minimally Invasive and Endoscopic Surgery, Interventional R ( Site 3658)
    • Lviv Oblast
      • Lviv, Lviv Oblast, Oekraïne, 79031
        • Actief, niet wervend
        • Municipal institution of Lviv regional council Lviv Oncology-Chemotherapy ( Site 3653)
    • Odesa Oblast
      • Odesa, Odesa Oblast, Oekraïne, 65055
        • Actief, niet wervend
        • Odessa Regional Oncology Center ( Site 3655)
    • Sumska Oblast
      • Sumy, Sumska Oblast, Oekraïne, 40022
        • Voltooid
        • Sumy regional clinical oncological dispensary-Oncothoracic department ( Site 3661)
    • Vinnytsia Oblast
      • Vinnytsia, Vinnytsia Oblast, Oekraïne, 21029
        • Voltooid
        • Communal Noncommercial Enterprise "Podillia Regional Oncology Center Of Vinnytsia Regional Council" ( Site 3662)
    • Zakarpattia Oblast
      • Uzhhorod, Zakarpattia Oblast, Oekraïne, 88000
        • Voltooid
        • Transcarpathian Regional Clinical Oncology Center-Chemotherapy dept. ( Site 3652)
      • Uzhhorod, Zakarpattia Oblast, Oekraïne, 88000
        • Werving
        • Uzhhorod City Multidisciplinary Clinical Hospital ( Site 3672)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +380312647211
    • Zaporizhzhia Oblast
      • Zaporizhzhya, Zaporizhzhia Oblast, Oekraïne, 69600
        • Voltooid
        • Municipal non-profit enterprise "Zaporizhzhia regional clinical hospital" of Zaporizhzhia regional c ( Site 3664)
    • Zhytomyr Oblast
      • Zhytomyr, Zhytomyr Oblast, Oekraïne, 10002
        • Actief, niet wervend
        • Zhytomyr Regional Oncology Center ( Site 3670)
      • Salzburg, Oostenrijk, 5020
        • Voltooid
        • Uniklinikum Salzburg ( Site 2956)
      • Vienna, Oostenrijk, 1090
        • Voltooid
        • Medizinische Universität Wien ( Site 2953)
      • Vienna, Oostenrijk, 1210
        • Werving
        • Klinik Floridsdorf-Abteilung für Innere Medizin und Pneumologie ( Site 2954)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +431277003855
    • Styria
      • Graz, Styria, Oostenrijk, 8036
        • Werving
        • Medical University of Graz ( Site 2952)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +4331638580321
    • Tyrol
      • Innsbruck, Tyrol, Oostenrijk, 6020
        • Werving
        • Medizinische Universitaet Innsbruck ( Site 2951)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +4351250422971
    • Upper Austria
      • Linz, Upper Austria, Oostenrijk, 4020
        • Werving
        • Ordensklinikum Linz GmbH Elisabethinen-Department of Pneumology ( Site 2957)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +4373276764226
      • Linz, Upper Austria, Oostenrijk, 4021
        • Voltooid
        • Kepler Universitätsklinikum ( Site 2955)
      • Lima, Peru, 15036
        • Werving
        • IPOR Instituto Peruano de Oncología & Radioterapia ( Site 0678)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +51012241598 Ext 121
      • Lima, Peru, 15038
        • Werving
        • INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS ( Site 0681)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +51012016500 Ext3009
      • Lima, Peru, 15102
        • Voltooid
        • Hospital Cayetano Heredia-Oncology ( Site 0675)
    • Greater Poland Voivodeship
      • Konin, Greater Poland Voivodeship, Polen, 62-500
        • Werving
        • Przychodnia Lekarska KOMED ( Site 1603)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 48632428009
      • Poznan, Greater Poland Voivodeship, Polen, 60-693
        • Werving
        • Med-Polonia Sp. z o. o. ( Site 1605)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 505758992
      • Poznan, Greater Poland Voivodeship, Polen, 61-848
        • Werving
        • Szpital Kliniczny im. Przemienienia Panskiego Uniwersytetu Medycznego im. K. Marcinkowskiego w Pozna ( Site 1601)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48618549014
      • Poznan, Greater Poland Voivodeship, Polen, 61-866
        • Werving
        • Wielkopolskie Centrum Onkologii im.M.Sklodowskiej-Curie ( Site 1619)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48 61 88 50 738
      • Poznan, Greater Poland Voivodeship, Polen, 60-569
        • Werving
        • Uniwersytecki Szpital Kliniczny w Poznaniu ( Site 1607)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 48618549038
    • Kuyavian-Pomeranian Voivodeship
      • Bydgoszcz, Kuyavian-Pomeranian Voivodeship, Polen, 85-796
        • Werving
        • Centrum Onkologii im. Prof. Franciszka Lukaszczyka ( Site 1612)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48523743589
    • Lesser Poland Voivodeship
      • Krakow, Lesser Poland Voivodeship, Polen, 31-115
        • Werving
        • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Oddzial w Krakowie ( Site 1608)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48126348245
      • Krakow, Lesser Poland Voivodeship, Polen, 31-826
        • Werving
        • Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie-Oncology Department ( Site 1618)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48 126468000
    • Masovian Voivodeship
      • Warsaw, Masovian Voivodeship, Polen, 01-748
        • Werving
        • Luxmed Onkologia sp. z o. o. ( Site 1621)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48224698363
      • Warsaw, Masovian Voivodeship, Polen, 02-781
        • Werving
        • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( Site 1604)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 48225463066
      • Warsaw, Masovian Voivodeship, Polen, 04-141
        • Werving
        • Wojskowy Instytut Medyczny-Klinika Onkologii ( Site 1606)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48226817235
    • Opole Voivodeship
      • Opole, Opole Voivodeship, Polen, 45-061
        • Werving
        • Opolskie Centrum Onkologii w Opolu im. prof. Tadeusza Kosza-Klinika Onkologii z Odcinkiem Dziennym ( Site 1616)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48774416084
    • Podlaskie Voivodeship
      • Bialystok, Podlaskie Voivodeship, Polen, 15-027
        • Werving
        • Bialostockie Centrum Onkologii ( Site 1610)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48692267220
    • Pomeranian Voivodeship
      • Gdansk, Pomeranian Voivodeship, Polen, 80-214
        • Werving
        • Uniwersyteckie Centrum Kliniczne-Klinika Chirurgii Onkologicznej, Transplantacyjnej i Ogólnej ( Site 1622)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 58 584 44 66
      • Gdynia, Pomeranian Voivodeship, Polen, 81-519
        • Werving
        • Szpital Morski im. PCK. Szpitale Pomorskie Sp. Z o.o ( Site 1625)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48583419348
    • Silesian Voivodeship
      • Gliwice, Silesian Voivodeship, Polen, 44-102
        • Werving
        • Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 1620)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 32 278 97 94
      • Racibórz, Silesian Voivodeship, Polen, 47-400
        • Werving
        • Szpital Rejonowy im. dr. J. Rostka w Raciborzu ( Site 1624)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48327555006
    • Warmian-Masurian Voivodeship
      • Olsztyn, Warmian-Masurian Voivodeship, Polen, 10-357
        • Werving
        • Warminsko-Mazurskie Centrum Chorob Pluc w Olsztynie ( Site 1623)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48895322978
    • West Pomeranian Voivodeship
      • Koszalin, West Pomeranian Voivodeship, Polen, 75-581
        • Werving
        • Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie ( Site 1614)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48502204953
    • Łódź Voivodeship
      • Brzeziny, Łódź Voivodeship, Polen, 95-060
        • Voltooid
        • Powiatowe Centrum Zdrowia w Brzezinach Sp. z o. o. Oddział Dziennej Chemioterapii ( Site 1611)
      • Lodz, Łódź Voivodeship, Polen, 93-338
        • Werving
        • Instytut Centrum Zdrowia Matki Polki-Klinika Onkologii ( Site 1609)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +48422711000
      • Lisbon, Portugal, 1769-001
        • Actief, niet wervend
        • Unidade Local de Saude de Santa Maria - Hospital Pulido Valente ( Site 1750)
      • Porto, Portugal, 4200-319
        • Voltooid
        • Centro Hospitalar de Sao Joao - Hospital de Sao Joao ( Site 1752)
      • Porto, Portugal, 4200-072
        • Actief, niet wervend
        • Instituto Português de Oncologia do Porto Francisco Gentil, EPE-Oncologia Médica ( Site 1753)
    • Lisbon District
      • Lisbon, Lisbon District, Portugal, 1400-038
        • Actief, niet wervend
        • Champalimaud Foundation ( Site 1751)
      • Ponce, Puerto Rico, 00717
        • Voltooid
        • Ad-Vance Medical Research-Research ( Site 1151)
      • San Juan, Puerto Rico, 00935
        • Voltooid
        • UPR Comprehensive Cancer Center ( Site 1150)
      • San Juan, Puerto Rico, 00927
        • Voltooid
        • FDI Clinical Research ( Site 1152)
      • Cluj-Napoca, Roemenië, 400015
        • Werving
        • Institutul Oncologic "Prof. Dr. Ioan Chiricuta" ( Site 3551)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +0264 598 362
      • Suceava, Roemenië, 720237
        • Werving
        • Spitalul Județean Sfântul Ioan cel Nou Suceava-Oncology ( Site 3550)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +40722423653
    • Bucharest
      • Bucharest, Bucharest, Roemenië, 013823
        • Werving
        • MEMORIAL HEALTHCARE INTERNATIONAL S.R.L ( Site 3553)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +40319393
    • Cluj
      • Cluj-Napoca, Cluj, Roemenië, 400015
        • Werving
        • Cardiomed SRL Cluj-Napoca ( Site 3555)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +40264406600
    • Dolj
      • Craiova, Dolj, Roemenië, 200347
        • Werving
        • Centrul de Oncologie "Sfântul Nectarie" ( Site 3552)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +40731604432
    • Timiș County
      • Timișoara, Timiș County, Roemenië, 300239
        • Werving
        • Cabinet Medical Oncomed ( Site 3554)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +40356460996
    • Altayskiy Kray
      • Barnaul, Altayskiy Kray, Rusland, 656045
        • Actief, niet wervend
        • Altai Regional Clinical Oncology Center ( Site 1229)
    • Baskortostan, Respublika
      • Ufa, Baskortostan, Respublika, Rusland, 450054
        • Actief, niet wervend
        • Republican Clinical Oncology Dispensary of Republic of Bashkortostan ( Site 1204)
      • Ufa, Baskortostan, Respublika, Rusland, 450083
        • Voltooid
        • Bashkir State Medical University ( Site 1221)
      • Ufa, Baskortostan, Respublika, Rusland, 450054
        • Voltooid
        • GBUZ Republican Clinical Oncological Dispensary-Antitumor drug therapy department ( Site 1250)
    • Belgorod Oblast
      • Belgorod, Belgorod Oblast, Rusland, 308010
        • Actief, niet wervend
        • Belgorod Oncology Dispensary ( Site 1213)
    • Chelyabinsk Oblast
      • Chelyabinsk, Chelyabinsk Oblast, Rusland, 454080
        • Voltooid
        • LLC Medical Centre "Lotos" ( Site 1253)
    • Ivanovo Oblast
      • Ivanovo, Ivanovo Oblast, Rusland, 153040
        • Actief, niet wervend
        • Regional Budgetary Healthcare Institution 'Ivanovo Regional Oncology Dispensary'-Urology ( Site 1219)
    • Krasnodarskiy Kray
      • Sochi, Krasnodarskiy Kray, Rusland, 354057
        • Actief, niet wervend
        • Oncological Dispensary #2 of Ministry of Health of Krasnodar region ( Site 1244)
    • Leningradskaya Oblast'
      • Saint-Petersburg, Leningradskaya Oblast', Rusland, 194291
        • Voltooid
        • GBUZ LOKB ( Site 1218)
      • Saint-Petersburg, Leningradskaya Oblast', Rusland, 194291
        • Actief, niet wervend
        • GBUZ LOKB-Oncology department #1 ( Site 1222)
    • Mordoviya, Respublika
      • Saransk, Mordoviya, Respublika, Rusland, 430005
        • Voltooid
        • Ogarev Mordovia State University ( Site 1206)
    • Moscow
      • Moscow, Moscow, Rusland, 115478
        • Voltooid
        • N.N. Blokhin NMRCO ( Site 1209)
      • Moscow, Moscow, Rusland, 125284
        • Voltooid
        • P. A. Hertsen Moscow Oncology Research Center ( Site 1214)
      • Moscow, Moscow, Rusland, 119991
        • Actief, niet wervend
        • First Moscow State Medical University n.a. I.M.Sechenov ( Site 1245)
      • Moscow, Moscow, Rusland, 105203
        • Voltooid
        • The National Medico-Surgical Center N.I. Pirogov ( Site 1225)
      • Moscow, Moscow, Rusland, 125367
        • Voltooid
        • FSAI Treatment and Rehabilitation Centre of the MoH and SD of RF ( Site 1208)
      • Moscow, Moscow, Rusland, 115478
        • Voltooid
        • Russian Oncological Research Center n.a. N.N.Blokhin of MoH ( Site 1201)
      • Moscow, Moscow, Rusland, 117485
        • Actief, niet wervend
        • Russian Scientific Center of Roentgenoradiology ( Site 1215)
      • Moscow, Moscow, Rusland, 115682
        • Actief, niet wervend
        • FSBI-FRCC of Special Types Med. Care and Technologies FMBA of Russia ( Site 1234)
      • Moscow, Moscow, Rusland, 125284
        • Actief, niet wervend
        • P. A. Hertsen Moscow Oncology Research Center ( Site 1247)
    • Nizhny Novgorod Oblast
      • Nizhny Novgorod, Nizhny Novgorod Oblast, Rusland, 603074
        • Actief, niet wervend
        • Volga District Medical Center Federal Medical and Biological Agency ( Site 1242)
    • Sankt-Peterburg
      • Saint Petersburg, Sankt-Peterburg, Rusland, 197022
        • Voltooid
        • EuroCityClinic ( Site 1230)
      • Saint Petersburg, Sankt-Peterburg, Rusland, 198255
        • Werving
        • City Clinical Oncology Center ( Site 1237)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +79675231217
      • Saint Petersburg, Sankt-Peterburg, Rusland, 191024
        • Voltooid
        • Russian Scientific Research Institute of Hematology and Blood Transfusion-Hematology ( Site 1224)
      • Saint Petersburg, Sankt-Peterburg, Rusland, 197022
        • Actief, niet wervend
        • First Pavlov State Medical University of Saint Petersburg ( Site 1232)
      • Saint Petersburg, Sankt-Peterburg, Rusland, 197341
        • Voltooid
        • Almazov National Medical Research Centre ( Site 1233)
      • Saint Petersburg, Sankt-Peterburg, Rusland, 194017
        • Voltooid
        • St. Petersburg Clinical Hospital of Russian Academy Of Sciences ( Site 1235)
      • Saint Petersburg, Sankt-Peterburg, Rusland, 197758
        • Voltooid
        • N.N.Petrov Research Institute of Oncology-Department of Preclinical and Clinical Research ( Site 1211)
      • Saint Petersburg, Sankt-Peterburg, Rusland, 197758
        • Voltooid
        • Clinical Research Center of specialized types medical care-Oncology ( Site 1205)
      • Saint Petersburg, Sankt-Peterburg, Rusland, 197758
        • Actief, niet wervend
        • National Medical Research Center of Oncology N.A. N.N. Petrov ( Site 1210)
    • Stavropol Kray
      • Pyatigorsk, Stavropol Kray, Rusland, 357502
        • Voltooid
        • GBUZ SK Pyatigorsk Interdistrict Oncology dispensary ( Site 1223)
    • Tatarstan, Respublika
      • Kazan', Tatarstan, Respublika, Rusland, 420029
        • Voltooid
        • Republican Clinical Oncology Dispensary of Tatarstan MoH named after professor M.Z. Sigal ( Site 1203)
      • Kazan', Tatarstan, Respublika, Rusland, 420029
        • Actief, niet wervend
        • Republican Clinical Oncology Dispensary ( Site 1228)
    • Tomsk Oblast
      • Tomsk, Tomsk Oblast, Rusland, 634028
        • Voltooid
        • Tomsk Scientific Research Institute of Oncology ( Site 1227)
    • Tyumen Oblast
      • Tyumen, Tyumen Oblast, Rusland, 625000
        • Actief, niet wervend
        • SAIH of the Tyumen region, Multidisciplinary Clinical Medical Center "Medical town" ( Site 1220)
    • Udmurtiya Republic
      • Izhevsk, Udmurtiya Republic, Rusland, 426009
        • Voltooid
        • Udmurtian Republican Clinical Oncology Center ( Site 1212)
    • Yaroslavl Oblast
      • Yaroslavl, Yaroslavl Oblast, Rusland, 150054
        • Actief, niet wervend
        • Yaroslavl Regional SBIH Clinical Oncology Hospital ( Site 1243)
    • Central Singapore
      • Singapore, Central Singapore, Singapore, 168583
        • Werving
        • National Cancer Centre Singapore ( Site 2200)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +6564368000
    • South West
      • Singapore, South West, Singapore, 119074
        • Werving
        • National University Hospital-Haematology -Oncology Research Group ( Site 2201)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +6567726825
      • Alicante, Spanje, 03010
        • Actief, niet wervend
        • Hospital General Universitario de Alicante-Oncologia ( Site 0881)
      • Barcelona, Spanje, 08003
        • Werving
        • Parc de Salut Mar - Hospital del Mar-Oncologia ( Site 0873)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34932483860
      • Barcelona, Spanje, 08035
        • Werving
        • H.U. Vall de Hebron ( Site 0850)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34934894158
      • Barcelona, Spanje, 08035
        • Werving
        • Hospital Vall d´Hebron Skin Cancer & Woman cancer therapeutic area ( Site 0887)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34 93 274 60 00
      • Barcelona, Spanje, 08035
        • Werving
        • Vall d´Hebron Gastric & Esophageal & Colorectal cancer therapeutic area ( Site 0889)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34 93 274 60 00
      • Barcelona, Spanje, 08035
        • Werving
        • Vall d´Hebron Prostatic & Renal & Bladder cancer therapeutic area ( Site 0888)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34 93 274 60 00
      • Córdoba, Spanje, 14004
        • Werving
        • Hospital Universitario Reina Sofia ( Site 0885)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34 957011456
      • Jaén, Spanje, 23007
        • Actief, niet wervend
        • Complejo Hospitalario de Jaén-Servicio de Oncología Médica ( Site 0879)
      • Madrid, Spanje, 28027
        • Werving
        • Clinica Universitaria de Navarra ( Site 0855)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34948255400
      • Madrid, Spanje, 28040
        • Werving
        • Hospital Clinico San Carlos ( Site 0857)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34913303000ext7768
      • Madrid, Spanje, 28040
        • Werving
        • Hospital Universitario Fundación Jiménez Díaz-Oncology & Hematology ( Site 0871)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34 91 550 48 00
      • Madrid, Spanje, 28041
        • Werving
        • Hospital General Universitario 12 de Octubre ( Site 0856)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34914692313
      • Madrid, Spanje, 28009
        • Werving
        • Hospital Universitario Gregorio Maranon ( Site 0864)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34914269393
      • Madrid, Spanje, 28050
        • Werving
        • Centro Integral Oncologico Clara Campal-Hospital HM Universitario Sanchinarro-START Madrid, ( Site 0869)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34917567825
      • Madrid, Spanje, 28046
        • Actief, niet wervend
        • Hospital Universitario La Paz ( Site 0853)
      • Málaga, Spanje, 29010
        • Werving
        • Hospital Universitario Virgen de la Victoria ( Site 0878)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34951032508
      • Seville, Spanje, 41009
        • Werving
        • Hospital Universitario Virgen Macarena-Unidad de Investigación Oncológica ( Site 0880)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34 671560092
      • Seville, Spanje, 41013
        • Werving
        • HOSPITAL UNIVERSITARIO VIRGEN DEL ROCIO-Medical Oncology ( Site 0872)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34915504800
      • Seville, Spanje, 41014
        • Werving
        • Hospital Universitario Virgen de Valme-Departamento de Oncologia ( Site 0882)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 34 955015273
      • Zaragoza, Spanje, 50009
        • Werving
        • Hospital Clinico Universitario Lozano Blesa ( Site 0859)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34976765746
    • Balearic Islands
      • Palma, Balearic Islands, Spanje, 07120
        • Voltooid
        • Hospital Universitari Son Espases-Oncologia ( Site 0883)
      • Palma de Mallorca, Balearic Islands, Spanje, 07198
        • Voltooid
        • Hospital Son Llatzer ( Site 0886)
    • Barcelona
      • L'Hospitalet de Llobregat, Barcelona, Spanje, 08907
        • Werving
        • Instituto Catalan de Oncologia ICO - Hospital Duran i Reynals ( Site 0860)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34932607744
    • Basque Country
      • San Sebastian- Donostia, Basque Country, Spanje, 20014
        • Werving
        • Hospital Universitario de Donostia ( Site 0890)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34943328338
    • Cantabria
      • Santander, Cantabria, Spanje, 39008
        • Werving
        • H. Marques de Valdecilla ( Site 0865)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34942202525
    • Catalonia
      • Badalona, Catalonia, Spanje, 08916
        • Actief, niet wervend
        • Institut Catala d Oncologia Hospital Germans Trias i Pujol ( Site 0851)
      • Barcelona, Catalonia, Spanje, 08036
        • Werving
        • Hospital Clinic de Barcelona ( Site 0852)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34932275402
      • Barcelona, Catalonia, Spanje, 08041
        • Voltooid
        • Hospital de la Santa Creu i Sant Pau-Oncología Médica ( Site 0862)
    • La Coruna
      • Santiago de Compostela, La Coruna, Spanje, 15706
        • Voltooid
        • CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 0876)
    • Las Palmas
      • Las Palmas de Gran Canaria, Las Palmas, Spanje, 35001
        • Werving
        • Hospital Universitario Insular de Gran Canaria ( Site 0867)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34961452191
    • Madrid
      • Majadahonda, Madrid, Spanje, 28222
        • Werving
        • Hospital Universitario Puerta de Hierro-Majadahonda ( Site 0861)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34911917759
      • Pozuelo de Alarcón, Madrid, Spanje, 28223
        • Voltooid
        • Hospital Universitario Quiron Madrid ( Site 0868)
    • Madrid, Comunidad de
      • Madrid, Madrid, Comunidad de, Spanje, 28034
        • Werving
        • Hospital Universitario Ramón y Cajal-Medical Oncology ( Site 0877)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34913368263
    • Malaga
      • Málaga, Malaga, Spanje, 29010
        • Werving
        • H.R.U Malaga - Hospital General ( Site 0884)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34 951308130
    • Principality of Asturias
      • Oviedo, Principality of Asturias, Spanje, 33011
        • Werving
        • Hospital Universitario Central de Asturias-Medical Oncology ( Site 0870)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 34 985108000 x36582
    • Tarragona
      • Reus, Tarragona, Spanje, 43204
        • Werving
        • Hospital Universitari Sant Joan de Reus-Oncology ( Site 0874)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34977310300
    • Valencia
      • Valencia, Valencia, Spanje, 46026
        • Voltooid
        • Hospital Universitari i Politecnic La Fe ( Site 0875)
    • Valenciana, Comunitat
      • Valencia, Valenciana, Comunitat, Spanje, 46009
        • Werving
        • Instituto Valenciano de Oncologia - IVO ( Site 0863)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +34961114605
      • Valencia, Valenciana, Comunitat, Spanje, 46015
        • Voltooid
        • Hospital Arnau de Vilanova ( Site 0866)
      • Valencia, Valenciana, Comunitat, Spanje, 46014
        • Voltooid
        • Hospital General Universitario de Valencia ( Site 0854)
      • Valencia, Valenciana, Comunitat, Spanje, 46010
        • Voltooid
        • Hospital Clinico de Valencia ( Site 0858)
      • Changhua, Taiwan, 50006
        • Werving
        • Changhua Christian Hospital ( Site 3210)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +88647238595
      • Hsinchu, Taiwan, 300195
        • Werving
        • National Taiwan University Hospital - Hsinchu branch ( Site 3208)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +88635326151
      • Kaohsiung City, Taiwan, 83301
        • Werving
        • Kaohsiung Chang Gung Memorial Hospital ( Site 3203)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +886975056230
      • Taichung, Taiwan, 40447
        • Werving
        • China Medical University Hospital ( Site 3204)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +886975681629
      • Taichung, Taiwan, 40705
        • Werving
        • Taichung Veterans General Hospital ( Site 3209)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +886423592525x3219
      • Tainan, Taiwan, 70457
        • Werving
        • National Cheng Kung University Hospital ( Site 3201)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 886-6-235-3535x5401
      • Taipei, Taiwan, 10048
        • Werving
        • National Taiwan University Hospital ( Site 3200)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +8862232123456
      • Taipei, Taiwan, 11217
        • Werving
        • Taipei Veterans General Hospital ( Site 3202)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +886228712121
      • Taipei, Taiwan, 10449
        • Werving
        • Mackay Memorial Hospital ( Site 3205)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +886225433535
      • Taipei, Taiwan, 112
        • Werving
        • Koo Foundation Sun Yat-Sen Cancer Center-Gynecology, Obstetrics, and women's health ( Site 3207)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +886228970011x1686
      • Taipei, Taiwan, 110
        • Werving
        • Taipei Medical University Hospital ( Site 3211)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +886227372181
      • Taoyuan, Taiwan, 33305
        • Werving
        • Chang Gung Medical Foundation-Linkou Branch ( Site 3206)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +88633281200x8468
    • Bangkok
      • Bangkok, Bangkok, Thailand, 10400
        • Werving
        • Ramathibodi Hospital. ( Site 2364)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +6622011671
      • Bangkoknoi, Bangkok, Thailand, 10700
        • Werving
        • Faculty of Medicine Siriraj Hospital ( Site 2365)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +6624194488
      • Pathumwan, Bangkok, Thailand, 10330
        • Werving
        • Chulalongkorn University ( Site 2363)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +6622516704
    • Changwat Khon Kaen
      • Muang, Changwat Khon Kaen, Thailand, 40002
        • Voltooid
        • Faculty of Medicine - Khon Kaen University ( Site 2366)
    • Changwat Songkhla
      • Hat Yai, Changwat Songkhla, Thailand, 90110
        • Werving
        • Songklanagarind Hospital ( Site 2367)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +6674451469
      • Olomouc, Tsjechië, 779 00
        • Werving
        • Fakultni nemocnice Olomouc ( Site 0701)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +420588441671
      • Prague, Tsjechië, 150 06
        • Voltooid
        • Fakultni nemocnice v Motole ( Site 0700)
    • Brno-mesto
      • Brno, Brno-mesto, Tsjechië, 656 53
        • Werving
        • Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 0703)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +420543132216
    • Olomouc Region
      • Olomouc, Olomouc Region, Tsjechië, 779 00
        • Werving
        • Fakultni nemocnice Olomouc-Onkologicka klinika ( Site 0704)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +420 588 444 288
    • Praha 4
      • Prague, Praha 4, Tsjechië, 140 59
        • Werving
        • Fakultni Thomayerova nemocnice-Onkologicka klinika 1. LF UK ( Site 0702)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +420261082531
    • Praha 5
      • Prague, Praha 5, Tsjechië, 150 06
        • Actief, niet wervend
        • Fakultni nemocnice v Motole-Onkologicka klinika 2. LF UK a FN Motol ( Site 0705)
      • Adana, Turkije (Türkiye), 01130
        • Werving
        • Acibadem Adana Hospital-Pediatric Hematology-Oncology ( Site 1312)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +905349179166
      • Adana, Turkije (Türkiye), 01250
        • Werving
        • Baskent University Dr. Turgut Noyan Research and Training Center-ONCOLOGY ( Site 1307)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +903223272727
      • Adana, Turkije (Türkiye), 01370
        • Werving
        • Adana Sehir Egitim ve Arastirma Hastanesi ( Site 1324)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +90 322 455 90 00
      • Ankara, Turkije (Türkiye), 06100
        • Werving
        • Ankara University Hospital Cebeci ( Site 1306)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +903125957115
      • Ankara, Turkije (Türkiye), 06230
        • Werving
        • Hacettepe Universitesi-oncology hospital ( Site 1304)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +905334318506
      • Ankara, Turkije (Türkiye), 06560
        • Werving
        • Gazi University Health Research and Application Center Gazi Hospital ( Site 1325)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 03122026970
      • Ankara, Turkije (Türkiye), 06800
        • Werving
        • Ankara City Hospital-Medical Oncology ( Site 1311)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +905551737206
      • Ankara, Turkije (Türkiye), 34180
        • Werving
        • Baskent Universitesi Ankara Hastanesi ( Site 1303)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 905333414050
      • Ankara, Turkije (Türkiye), 06620
        • Werving
        • Ankara University Health Practice and Research Hospitals ( Site 1331)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 00903124663550
      • Ankara, Turkije (Türkiye), 06680
        • Werving
        • Liv Hospital Ankara ( Site 1330)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 444 6 623
      • Antalya, Turkije (Türkiye), 07059
        • Werving
        • Akdeniz Universitesi Hastanesi-Medical Onkology ( Site 1318)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 90 (242) 249 60 00
      • Antalya, Turkije (Türkiye), 07090
        • Actief, niet wervend
        • Memorial Antalya Hospital-Oncology ( Site 1315)
      • Edirne, Turkije (Türkiye), 22030
        • Werving
        • Trakya Universitesi Tip Fakultesi ( Site 1301)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +902842360910
      • Erzurum, Turkije (Türkiye), 25240
        • Werving
        • Atatürk Üniversitesi ( Site 1333)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +90 442 344 66 66
      • Istanbul, Turkije (Türkiye), 34093
        • Werving
        • Bezmialem Vakf Üniversitesi-Oncology ( Site 1308)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 444 0 600
      • Istanbul, Turkije (Türkiye), 34457
        • Werving
        • Acıbadem Maslak Hastanesi-Medical Oncology ( Site 1321)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +902123034813
      • Istanbul, Turkije (Türkiye), 34668
        • Werving
        • Istanbul Universitesi Cerrahpasa-Medical Oncology ( Site 1302)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +902124143434
      • Istanbul, Turkije (Türkiye), 34722
        • Werving
        • TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1316)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +905063509061
      • Istanbul, Turkije (Türkiye), 34899
        • Werving
        • Marmara Universitesi Pendik Egitim Arastirma Hastanesi-Medical Oncology ( Site 1305)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +905323702473
      • Istanbul, Turkije (Türkiye), 34214
        • Werving
        • Medipol Mega Universite Hastanesi ( Site 1326)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +90212447244
      • Istanbul, Turkije (Türkiye), 34766
        • Werving
        • Umraniye Training and Research Hospital ( Site 1329)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0216 632 1818
      • Istanbul, Turkije (Türkiye), 34303
        • Voltooid
        • Acibadem Universitesi Atakent Hastanesi ( Site 1319)
      • Istanbul, Turkije (Türkiye), 34093
        • Actief, niet wervend
        • Istanbul University Capa Campus ( Site 1314)
      • Izmir, Turkije (Türkiye), 35040
        • Werving
        • Ege Universitesi Tip Fakultesi Hastanesi ( Site 1300)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 905337360674
      • Izmir, Turkije (Türkiye), 35577
        • Actief, niet wervend
        • I.E.U. Medical Point Hastanesi-Oncology ( Site 1310)
      • Kocaeli, Turkije (Türkiye), 41380
        • Werving
        • Kocaeli Üniversitesi ( Site 1313)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +902623037575
      • Malatya, Turkije (Türkiye), 44280
        • Werving
        • Inonu Universitesi ( Site 1309)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +905385003562
      • Sakarya, Turkije (Türkiye), 54100
        • Werving
        • Sakarya University School of Medicine ( Site 1332)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +0902648884000
      • Samsun, Turkije (Türkiye), 55200
        • Werving
        • Samsun Medical Park Hastanesi ( Site 1328)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +9 0 362 311 40 40
    • Istanbul
      • Üsküdar /Istanbul, Istanbul, Turkije (Türkiye)
        • Actief, niet wervend
        • Acibadem Altunizade Hospital-Oncology ( Site 1317)
    • İzmir
      • Balçova, İzmir, Turkije (Türkiye), 35340
        • Werving
        • Dokuz Eylul Universitesi Hastanesi ( Site 1323)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +902324129898
      • Coventry, Verenigd Koninkrijk, CV2 2DX
        • Actief, niet wervend
        • University Hospital Coventry & Warwickshire ( Site 0524)
      • Leeds, Verenigd Koninkrijk, LS9 7TF
        • Werving
        • St James University Hospital ( Site 0509)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +441132068320
      • Sutton, Verenigd Koninkrijk, SM2 5PT
        • Werving
        • The Royal Marsden NHS Foundation Trust. ( Site 0513)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +4402073528171
      • Wolverhampton, Verenigd Koninkrijk, WV10 0QP
        • Actief, niet wervend
        • New Cross Hospital-Department of Oncology ( Site 0517)
    • Aberdeen City
      • Aberdeen, Aberdeen City, Verenigd Koninkrijk, AB25 2ZN
        • Actief, niet wervend
        • Aberdeen Royal Infirmary-Department of Oncology ( Site 0521)
    • Cambridgeshire
      • Cambridge, Cambridgeshire, Verenigd Koninkrijk, CB2 2QQ
        • Actief, niet wervend
        • Addenbrookes Hospital ( Site 0522)
    • Edinburgh, City of
      • Edinburgh, Edinburgh, City of, Verenigd Koninkrijk, EH4 2XU
        • Werving
        • Western General Hospital ( Site 0502)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +441315371000
    • England
      • Manchester, England, Verenigd Koninkrijk, M20 4BX
        • Werving
        • The Christie ( Site 0516)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 01614463000
      • Sheffield, England, Verenigd Koninkrijk, S10 2SJ
        • Werving
        • Weston Park Hospital ( Site 0519)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 0114 2265000
    • Essex
      • Broomfield, Essex, Verenigd Koninkrijk, CM1 7ET
        • Voltooid
        • Mid Essex Hospitals Service Trust. Broomfield Hospital ( Site 0503)
    • Glasgow City
      • Glasgow, Glasgow City, Verenigd Koninkrijk, G12 0YN
        • Werving
        • The Beatson West of Scotland Cancer Centre ( Site 0506)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +441413017073
    • Lancashire
      • Preston, Lancashire, Verenigd Koninkrijk, PR2 9HT
        • Werving
        • Royal Preston Hospital ( Site 0518)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 01772 524656
    • London, City of
      • London, London, City of, Verenigd Koninkrijk, EC1A 7BE
        • Werving
        • Barts Health NHS Trust ( Site 0512)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +442034657108
      • London, London, City of, Verenigd Koninkrijk, NW1 2PG
        • Werving
        • University College London Hospital-Cancer Clinical Trials Unit ( Site 0520)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 07943 094 762
      • London, London, City of, Verenigd Koninkrijk, NW3 2QG
        • Actief, niet wervend
        • Royal Free Hospital ( Site 0507)
      • London, London, City of, Verenigd Koninkrijk, SW3 6JJ
        • Werving
        • Royal Marsden Hospital ( Site 0505)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +442078082132
      • London, London, City of, Verenigd Koninkrijk, W1G 6AD
        • Voltooid
        • Sarah Cannon Research UK ( Site 0504)
    • Northern Ireland
      • Belfast, Northern Ireland, Verenigd Koninkrijk, BT9 7AB
        • Voltooid
        • Belfast City Hospital ( Site 0508)
    • Nottinghamshire
      • Nottingham, Nottinghamshire, Verenigd Koninkrijk, NG5 1PB
        • Actief, niet wervend
        • Nottingham University Hospitals NHS Trust ( Site 0510)
    • Arizona
      • Tucson, Arizona, Verenigde Staten, 85719
        • Werving
        • Arizona Cancer Center at UMC North ( Site 0018)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 520-694-1053
    • California
      • Bakersfield, California, Verenigde Staten, 93309
        • Werving
        • Comprehensive Blood & Cancer Center [Bakersfield, CA] ( Site 0054)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 661-322-2206
      • Fresno, California, Verenigde Staten, 93720
        • Voltooid
        • California Cancer Associates for Research & Excellence ( Site 0016)
      • Fullerton, California, Verenigde Staten, 92835
        • Voltooid
        • Providence Medical Foundation ( Site 0087)
      • Los Angeles, California, Verenigde Staten, 90025
        • Actief, niet wervend
        • The Angeles Clinic and Research Institute ( Site 0005)
      • Los Angeles, California, Verenigde Staten, 90095
        • Werving
        • UCLA - Hematology/Oncology - Administrative Office ( Site 0009)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 310-794-6913
      • Orange, California, Verenigde Staten, 92868
        • Voltooid
        • University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0076)
      • Palo Alto, California, Verenigde Staten, 94304
        • Werving
        • Stanford Cancer Center ( Site 0086)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 650-721-7489
      • San Francisco, California, Verenigde Staten, 94158
        • Werving
        • UCSF Helen Diller Family Comprehensive Cancer Center ( Site 0004)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 415-514-6382
      • Santa Monica, California, Verenigde Staten, 90404
        • Werving
        • Providence Saint John's Health Center ( Site 0059)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 310-449-5244
    • Colorado
      • Aurora, Colorado, Verenigde Staten, 80045
        • Werving
        • University of Colorado Cancer Center ( Site 0021)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 720-848-7135
    • Connecticut
      • New Haven, Connecticut, Verenigde Staten, 06510
        • Voltooid
        • Yale Cancer Center ( Site 0014)
    • District of Columbia
      • Washington D.C., District of Columbia, Verenigde Staten, 20007
        • Actief, niet wervend
        • Georgetown University Medical Center ( Site 0023)
    • Florida
      • Fort Lauderdale, Florida, Verenigde Staten, 33308
        • Werving
        • Holy Cross Hospital, Michael & Dianne Bienes Comp Cancer Ctr ( Site 0022)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 954-776-3036
      • Jacksonville, Florida, Verenigde Staten, 32207
        • Voltooid
        • Baptist MD Anderson Cancer Center ( Site 0083)
      • Miami Beach, Florida, Verenigde Staten, 33140
        • Werving
        • Mount Sinai Braman Comprehensive Cancer Center ( Site 0031)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 305-674-2625
      • Tampa, Florida, Verenigde Staten, 33612
        • Voltooid
        • Moffitt Cancer Center ( Site 0011)
    • Georgia
      • Atlanta, Georgia, Verenigde Staten, 30322
        • Voltooid
        • Emory School of Medicine ( Site 0013)
      • Augusta, Georgia, Verenigde Staten, 30912
        • Voltooid
        • Augusta University ( Site 0077)
      • Marietta, Georgia, Verenigde Staten, 30060
        • Werving
        • Northwest Georgia Oncology Centers PC ( Site 0061)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 770-281-5124
    • Hawaii
      • Honolulu, Hawaii, Verenigde Staten, 96819
        • Voltooid
        • Kaiser Permanente Moanalua Medical Center ( Site 0063)
    • Illinois
      • Chicago, Illinois, Verenigde Staten, 60637
        • Werving
        • The University of Chicago ( Site 0020)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 773-834-7961
    • Iowa
      • Iowa City, Iowa, Verenigde Staten, 52242
        • Werving
        • University of Iowa Hospital and Clinics ( Site 0026)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 319-356-1228
    • Kentucky
      • Louisville, Kentucky, Verenigde Staten, 40202
        • Werving
        • James Graham Brown Cancer Center ( Site 0058)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 502-562-4673
      • Paducah, Kentucky, Verenigde Staten, 42003
        • Werving
        • Mercy Health-Paducah Cancer Center ( Site 0084)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 270-441-4343
    • Louisiana
      • Covington, Louisiana, Verenigde Staten, 70433
        • Werving
        • Women's Cancer Care ( Site 0088)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 985-317-6005
    • Maryland
      • Baltimore, Maryland, Verenigde Staten, 21237
        • Werving
        • MedStar Franklin Square Medical Center ( Site 0046)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 443-777-7364
      • Baltimore, Maryland, Verenigde Staten, 21287
        • Werving
        • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ( Site 0056)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 410-955-5222
      • Columbia, Maryland, Verenigde Staten, 21044
        • Werving
        • Maryland Oncology Hematology (MOH) ( Site 8000)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 410-964-2212
    • Massachusetts
      • Boston, Massachusetts, Verenigde Staten, 02114
        • Actief, niet wervend
        • Massachusetts General Hospital ( Site 0041)
      • Boston, Massachusetts, Verenigde Staten, 02215
        • Actief, niet wervend
        • Dana-Farber Cancer Institute ( Site 0006)
    • Michigan
      • Detroit, Michigan, Verenigde Staten, 48201
        • Werving
        • Karmanos Cancer Institute ( Site 0047)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 800-527-6266
    • Minnesota
      • Rochester, Minnesota, Verenigde Staten, 55905
        • Actief, niet wervend
        • Mayo Clinic in Rochester, Minnesota ( Site 0002)
    • Nevada
      • Las Vegas, Nevada, Verenigde Staten, 89169
        • Werving
        • Comprehensive Cancer Centers of Nevada ( Site 0043)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 702-952-3400
    • New Jersey
      • Hackensack, New Jersey, Verenigde Staten, 07601
        • Actief, niet wervend
        • John Theurer Cancer Center at Hackensack University Medical Center ( Site 0038)
      • New Brunswick, New Jersey, Verenigde Staten, 08901
        • Werving
        • Cancer Institute of New Jersey ( Site 0025)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 917-991-4174
    • New York
      • New York, New York, Verenigde Staten, 10016
        • Werving
        • Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 0032)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 212-731-5431
      • New York, New York, Verenigde Staten, 10065
        • Voltooid
        • Memorial Sloan Kettering Cancer Center ( Site 0012)
      • White Plains, New York, Verenigde Staten, 10601
        • Werving
        • White Plains Hospital-Center for Cancer Care ( Site 0069)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 914-849-7630
    • North Carolina
      • Cary, North Carolina, Verenigde Staten, 27518
        • Actief, niet wervend
        • WakeMed Cancer Care - Waverly Hematology & Medical Oncology ( Site 0074)
      • Chapel Hill, North Carolina, Verenigde Staten, 27514
        • Werving
        • University of North Carolina at Chapel Hill ( Site 0040)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 919-843-7713
      • Charlotte, North Carolina, Verenigde Staten, 28204
        • Actief, niet wervend
        • Levine Cancer Institute ( Site 0034)
      • Durham, North Carolina, Verenigde Staten, 27710
        • Werving
        • Duke Cancer Center ( Site 0028)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 919-668-3771
    • North Dakota
      • Fargo, North Dakota, Verenigde Staten, 58102
        • Voltooid
        • Sanford Fargo Medical Center-Roger Maris Cancer Center ( Site 0065)
    • Ohio
      • Cleveland, Ohio, Verenigde Staten, 44106
        • Voltooid
        • University Hospitals ( Site 0044)
    • Oklahoma
      • Tulsa, Oklahoma, Verenigde Staten, 74146
        • Werving
        • Oklahoma Cancer Specialists and Research Institute, LLC ( Site 0082)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 918-505-3200
    • Oregon
      • Portland, Oregon, Verenigde Staten, 97225
        • Voltooid
        • Providence Portland Medical Center ( Site 0051)
    • Pennsylvania
      • Easton, Pennsylvania, Verenigde Staten, 18045
        • Voltooid
        • St. Luke's University Health Network ( Site 0017)
      • Philadelphia, Pennsylvania, Verenigde Staten, 19104
        • Werving
        • University of Pennsylvania ( Site 0010)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 215-662-7908
      • Philadelphia, Pennsylvania, Verenigde Staten, 19111
        • Werving
        • Fox Chase Cancer Center ( Site 0042)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 215-214-4297
      • Pittsburgh, Pennsylvania, Verenigde Staten, 15232
        • Werving
        • UPMC Hillman Cancer Center ( Site 0008)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 412-623-3272
    • South Carolina
      • Greenville, South Carolina, Verenigde Staten, 29607
        • Voltooid
        • Saint Francis Health System ( Site 0089)
    • South Dakota
      • Sioux Falls, South Dakota, Verenigde Staten, 57104
        • Voltooid
        • Sanford Cancer Center ( Site 0066)
    • Tennessee
      • Germantown, Tennessee, Verenigde Staten, 38138
        • Voltooid
        • West Cancer Center and Research Institute ( Site 0055)
      • Nashville, Tennessee, Verenigde Staten, 37204
        • Werving
        • Vanderbilt Health One Hundred Oaks Diagnostic ( Site 0060)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 615-936-6726
      • Nashville, Tennessee, Verenigde Staten, 37232
        • Werving
        • Vanderbilt University Medical Center-Vanderbilt-Ingram Cancer Center ( Site 0015)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 615-936-6726
    • Texas
      • Austin, Texas, Verenigde Staten, 78745
        • Werving
        • Texas Oncology - Central/South Texas ( Site 8001)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 512-447-2202
      • Dallas, Texas, Verenigde Staten, 75246
        • Werving
        • Texas Oncology-Baylor Sammons Cancer Center ( Site 0062)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 214-370-1000
      • Houston, Texas, Verenigde Staten, 77030
        • Werving
        • University of Texas MD Anderson Cancer Center ( Site 0007)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 713-792-2921
      • San Antonio, Texas, Verenigde Staten, 78229
        • Werving
        • South Texas Accelerated Research Therapeutics, LLC (START) ( Site 0001)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 210-593-5265
    • Virginia
      • Charlottesville, Virginia, Verenigde Staten, 22908
        • Werving
        • University of Virginia Health System ( Site 0035)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 434-243-6303
      • Midlothian, Virginia, Verenigde Staten, 23114
        • Voltooid
        • Bon Secours St. Francis Medical Center-Oncology Research ( Site 0075)
      • Richmond, Virginia, Verenigde Staten, 23219
        • Werving
        • VCU Health Adult Outpatient Pavillion ( Site 0080)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 804-628-6430
      • Roanoke, Virginia, Verenigde Staten, 24014
        • Werving
        • Blue Ridge Cancer Care ( Site 0067)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 540-491-2244
    • Washington
      • Bellevue, Washington, Verenigde Staten, 98004
        • Werving
        • Fred Hutchinson Cancer Center ( Site 0024)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 206-606-8245
    • Hanoi
      • Hanoi, Hanoi, Vietnam, 100000
        • Actief, niet wervend
        • Hanoi Oncology Hospital ( Site 3780)
      • Hanoi, Hanoi, Vietnam, 100000
        • Actief, niet wervend
        • K Hospital - National Cancer Hospital ( Site 3783)
      • Hanoi, Hanoi, Vietnam, 100000
        • Voltooid
        • National Lung Hospital ( Site 3781)
      • Seoul, Zuid -Korea, 03080
        • Werving
        • Seoul National University Hospital ( Site 0953)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +82220720850
      • Seoul, Zuid -Korea, 03722
        • Werving
        • Severance Hospital ( Site 0954)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +82222288130
      • Seoul, Zuid -Korea, 03722
        • Werving
        • Severance Hospital, Yonsei University Health System ( Site 0962)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +82-2-2228-4190
      • Seoul, Zuid -Korea, 06351
        • Werving
        • Samsung Medical Center ( Site 0950)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: 82234103438
      • Seoul, Zuid -Korea, 06351
        • Werving
        • Samsung Medical Center ( Site 0970)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +821020154932
      • Seoul, Zuid -Korea, 06351
        • Werving
        • Samsung Medical Center ( Site 0971)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +82234106250
      • Seoul, Zuid -Korea, 06591
        • Voltooid
        • The Catholic Univ. of Korea Seoul St. Mary's Hospital ( Site 0972)
      • Seoul, Zuid -Korea, 08308
        • Actief, niet wervend
        • Korea University Guro Hospital ( Site 0963)
      • Seoul, Zuid -Korea, 02841
        • Actief, niet wervend
        • Korea University Anam Hospital ( Site 0956)
    • Incheon
      • Inceon, Incheon, Zuid -Korea, 21565
        • Voltooid
        • Gachon University Gil Medical Center ( Site 0967)
    • Jeonranamdo
      • Hwasun, Jeonranamdo, Zuid -Korea, 58128
        • Actief, niet wervend
        • Chonnam National University Hwasun Hospital-Hemato-Oncology ( Site 0959)
    • Kyonggi-do
      • Goyang-si, Kyonggi-do, Zuid -Korea, 10408
        • Actief, niet wervend
        • National Cancer Center ( Site 0955)
      • Seongnam-si, Kyonggi-do, Zuid -Korea, 13620
        • Werving
        • Seoul National University Bundang Hospital ( Site 0951)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +82215883369
      • Seongnam-si, Kyonggi-do, Zuid -Korea, 13496
        • Actief, niet wervend
        • CHA Bundang Medical Center CHA University ( Site 0957)
      • Suwon, Kyonggi-do, Zuid -Korea, 16247
        • Werving
        • The Catholic University Of Korea St. Vincent's Hospital ( Site 0968)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +82312498153
      • Suwon, Kyonggi-do, Zuid -Korea, 16499
        • Actief, niet wervend
        • Ajou University Hospital ( Site 0969)
    • North Chungcheong
      • Cheongju-si, North Chungcheong, Zuid -Korea, 28644
        • Actief, niet wervend
        • Chungbuk National University Hospital ( Site 0961)
    • Seoul
      • Gangnam-gu, Seoul, Zuid -Korea, 06273
        • Voltooid
        • Gangnam Severance Hospital, Yonsei University Health System ( Site 0966)
      • Songpagu, Seoul, Zuid -Korea, 05505
        • Werving
        • Asan Medical Center ( Site 0952)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +82216887575
    • Taegu-Kwangyokshi
      • Daegu, Taegu-Kwangyokshi, Zuid -Korea, 42601
        • Actief, niet wervend
        • Keimyung University Dongsan Hospital CRC room 1 ( Site 0960)
      • Deagu, Taegu-Kwangyokshi, Zuid -Korea, 41404
        • Actief, niet wervend
        • Kyungpook National University Chilgok Hospital ( Site 0964)
    • Taejon-Kwangyokshi
      • Daejeon, Taejon-Kwangyokshi, Zuid -Korea, 35015
        • Actief, niet wervend
        • Chungnam national university hospital-Department of Internal Medicine ( Site 0958)
    • Gauteng
      • Johannesburg, Gauteng, Zuid-Afrika, 2193
        • Werving
        • WCR Office ( Site 2002)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +27113390600
      • Pretoria, Gauteng, Zuid-Afrika, 0181
        • Werving
        • LIFE GROENKLOOF-Mary Potter Cancer Centre ( Site 2005)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +27123466701
      • Pretoria, Gauteng, Zuid-Afrika, 0040
        • Werving
        • Wilgers Oncology Centre ( Site 2006)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +27128072744
      • Sandton, Gauteng, Zuid-Afrika, 2196
        • Werving
        • Sandton Oncology Medical Group (Pty) Ltd-Research ( Site 2004)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +27118830900
    • KwaZulu-Natal
      • Durban, KwaZulu-Natal, Zuid-Afrika, 4091
        • Werving
        • The Oncology Centre ( Site 2000)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +27312088666
    • Western Cape
      • Cape Town, Western Cape, Zuid-Afrika, 7570
        • Werving
        • Cape Town Oncology Trials ( Site 2007)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +27219443832
      • George, Western Cape, Zuid-Afrika, 6520
        • Werving
        • GVI Oncology ( Site 2008)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +448840806
    • Stockholm County
      • Stockholm, Stockholm County, Zweden, 171 76
        • Werving
        • Karolinska Universitetssjukhuset Solna ( Site 0802)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +46851770000
    • Uppsala County
      • Uppsala, Uppsala County, Zweden, 751 85
        • Werving
        • Blod och Tumorssjukdomar. Akademiska sjukhuset ( Site 0801)
        • Contact:
          • Study Coordinator
          • Telefoonnummer: +46186110000
    • Västerbotten County
      • Umeå, Västerbotten County, Zweden, 901 85
        • Voltooid
        • Norrlands Universitetssjukhus ( Site 0800)
    • Västra Götaland County
      • Gothenburg, Västra Götaland County, Zweden, 413 45
        • Voltooid
        • Sahlgrenska Universitetssjukhuset-Department of Oncology CTU Clinical Trial Unit ( Site 0803)
    • Canton of Basel-City
      • Basel, Canton of Basel-City, Zwitserland, 4031
        • Actief, niet wervend
        • University Hospital Basel ( Site 0752)
    • Canton of Geneva
      • Geneva, Canton of Geneva, Zwitserland, 1211
        • Actief, niet wervend
        • Hôpitaux Universitaires de Genève (HUG) ( Site 0753)
    • Canton of Zurich
      • Zürich-Flughafen, Canton of Zurich, Zwitserland, 8058
        • Actief, niet wervend
        • Universitaetsspital Zuerich ( Site 0750)

Deelname Criteria

Onderzoekers zoeken naar mensen die aan een bepaalde beschrijving voldoen, de zogenaamde geschiktheidscriteria. Enkele voorbeelden van deze criteria zijn iemands algemene gezondheidstoestand of eerdere behandelingen.

Geschiktheidscriteria

Leeftijden die in aanmerking komen voor studie

18 jaar en ouder (Volwassen, Oudere volwassene)

Accepteert gezonde vrijwilligers

Nee

Geslachten die in aanmerking komen voor studie

Allemaal

Beschrijving

Inclusion Criteria:

  • Treated on the parent pembrolizumab studies established by the Sponsor as MK-3475-587 ready.
  • Currently receiving pembrolizumab, pembrolizumab based combinations or lenvatinib from parent studies or in a follow-up phase.

Additional eligibility criteria for participants who enter Second Course Phase once they are enrolled on MK-3475-587:

  • Has not received any anticancer systemic treatment since the last dose of pembrolizumab or a pembrolizumab-based combination in First Course Phase.
  • Has an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.
  • Demonstrates adequate organ function.
  • Have resolution of any toxic effect(s) of First Course Phase trial treatment with pembrolizumab or a pembrolizumab-based combination to Grade 1 or less (except alopecia) before trial treatment in Second Course Phase is started. If participant received major surgery or radiation therapy of >30 Gray (Gy), they must have recovered from the toxicity and/or complications of the intervention.
  • A female participant is eligible to enroll if she is not pregnant, not breastfeeding, and ≥1 of the following conditions applies: A woman of childbearing potential (WOCBP) who agrees to use contraception during the study treatment period and for ≥120 days (corresponding to time needed to eliminate any study combination treatment(s) plus 30 days (a menstruation cycle) for study treatments with risk of genotoxicity.

Additional eligibility criteria for participants who enter dosing with Lenvatinib:

  • Adequately controlled blood pressure (BP) to <150/90 mmHg, with or without antihypertensive medications.
  • For male agrees to be abstinent from penile-vaginal intercourse OR agrees to use a highly effective contraceptive method while receiving study drug and for 7 days after the last dose of lenvatinib.
  • Is female and not pregnant/breastfeeding and at least one of the following applies during the study and for ≥4 days after: is not a woman of childbearing potential (WOCBP), is a WOCBP and uses highly effective contraception (low user dependency method OR a user dependent hormonal method in combination with a barrier method) or is a WOCBP who is abstinent from heterosexual intercourse.

Exclusion Criteria:

-There are no exclusion criteria to participate in MK-3475-587.

Participants are excluded from entering Second Course trial treatment once they are enrolled on MK-3475-587 if any of the following criteria applies:

  • Has severe hypersensitivity (≥ Grade 3) to pembrolizumab and/or any of its excipients.
  • Has received a live vaccine within 30 days prior to the first dose of Second Course Phase trial treatment.
  • Has a diagnosis of immunodeficiency or is receiving chronic systemic steroid therapy (in dosing exceeding 10 mg daily of prednisone equivalent) or any other form of immunosuppressive therapy within 7 days prior to the Cycle 1 Day 1 of Second Course Phase.
  • Has a known additional malignancy that is progressing or requires active treatment. Exceptions include early stage cancers (carcinoma in situ or Stage 1) treated with curative intent, melanoma (non-ulcerated, thin primary), basal cell carcinoma of the skin, squamous cell carcinoma of the skin, in situ cervical cancer, or in situ breast cancer that has undergone potentially curative therapy.
  • Has known active central nervous system metastases and/or carcinomatous meningitis.
  • Has an active autoimmune disease that has required systemic treatment in the past 2 years (i.e., use of disease modifying agents, corticosteroids or immunosuppressive drugs). Replacement therapy (e.g. thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency) is not considered a form of systemic treatment and is allowed.
  • Has a history of (non-infectious) pneumonitis that required steroids or has current pneumonitis. Note: Participants that experienced pneumonitis during First Course that did not meet the criteria for permanent discontinuation are eligible.
  • Non-small cell lung cancer (NSCLC) participants only: Has interstitial lung disease.
  • Has an active infection requiring systemic therapy.
  • Has a known history of human immunodeficiency virus (HIV) infection.
  • Has a known history of or is positive for hepatitis B or hepatitis C. For parent studies where inclusion of participants with hepatitis was permitted, MK-3475-587 will follow the parent study eligibility criteria for hepatitis.
  • Is pregnant or breastfeeding or expecting to conceive or father children within the projected duration of the study, starting with the Second Course Phase eligibility Visit through 120 days after the last dose of study treatment.
  • Has severe cardiovascular disease, i.e., arrhythmias, requiring chronic treatment, congestive heart failure (New York Heart Association Class III or IV) or symptomatic ischemic heart disease.
  • Has hepatic decompensation (Child-Pugh score >6 [class B and C]).
  • Has uncontrolled thyroid dysfunction.
  • Has uncontrolled diabetes mellitus.
  • Has had an allogeneic tissue/solid organ transplant.
  • Has a known history of active tuberculosis (TB; Bacillus tuberculosis).

Additional exclusion criteria for participants who enter dosing with Lenvatinib:

  • Has had major surgery within 3 weeks prior to first dose of study intervention(s).
  • Has preexisting ≥Grade 3 gastrointestinal or non-gastrointestinal fistula.
  • Has urine protein ≥1 g/24 hours.
  • Has LVEF below the institutional (or local laboratory) normal range, as determined by multigated acquisition scan (MUGA) or echocardiogram (ECHO).
  • Has radiographic evidence of encasement or invasion of a major blood vessel, or of intratumoral cavitation.
  • Prolongation of QT intervals corrected for heart rate using Fridericia's (cube root) correction (QTcF) interval to >480 ms.
  • Has clinically significant cardiovascular disease within 12 months from first dose of study intervention, including New York Heart Association Class III or IV congestive heart failure, unstable angina, myocardial infarction, cerebral vascular accident, or cardiac arrhythmia associated with hemodynamic instability.
  • Gastrointestinal malabsorption or any other condition that might affect the absorption of lenvatinib.
  • Active hemoptysis (bright red blood of at least 0.5 teaspoon) within 3 weeks prior to the first dose of study drug.
  • Has a history of any contraindication or has a severe hypersensitivity to any components of lenvatinib.

Studie plan

Dit gedeelte bevat details van het studieplan, inclusief hoe de studie is opgezet en wat de studie meet.

Hoe is de studie opgezet?

Ontwerpdetails

  • Primair doel: Behandeling
  • Toewijzing: Niet-gerandomiseerd
  • Interventioneel model: Parallelle opdracht
  • Masker: Geen (open label)

Wapens en interventies

Deelnemersgroep / Arm
Interventie / Behandeling
Experimenteel: Pembrolizumab 200 mg

Participants receive pembrolizumab 200 mg via intravenous (IV) infusion on Day 1 of each 3-week cycle for up to 35 administrations or more for First Course participants and up to 17 administrations for Second Course participants.

200 or 400 mg IV infusion

Andere namen:
  • MK-3475
  • KEYTRUDA®
Experimenteel: Pembrolizumab 400 mg

Participants receive pembrolizumab 400 mg via intravenous (IV) infusion on Day 1 of each 6-week cycle for up to 17 administrations or more for First Course participants and up to 8 administrations for Second Course participants.

200 or 400 mg IV infusion

Andere namen:
  • MK-3475
  • KEYTRUDA®
Experimenteel: Pembrolizumab 200 mg + SOC: Per Parent Study)

Participants receive pembrolizumab 200 mg via IV infusion on Day 1 of each 3-week cycle PLUS standard of care (SOC) treatment (or per parent study if there is no SOC) for up to 35 administrations or more for First Course participants and up to 17 administrations for Second Course participants. Participants receiving a pembrolizumab-based combination treatment will receive the dose regimen of the combination drug(s) which is recommended per SOC or was used in the parent study protocol if there is no SOC recommendation.

200 or 400 mg IV infusion

Andere namen:
  • MK-3475
  • KEYTRUDA®

IV infusion or oral tablets

Experimenteel: Pembrolizumab 400 mg + SOC (Per Parent Study)

Participants receive pembrolizumab 400 mg via IV infusion on Day 1 of each 6-week cycle PLUS SOC treatment (or per parent study if there is no SOC) for up to 17 administrations or more for First Course participants and up to 8 administrations for Second Course participants. Participants receiving a pembrolizumab-based combination treatment will receive the dose regimen of the combination drug(s) which is recommended per SOC or was used in the parent study protocol if there is no SOC recommendation.

200 or 400 mg IV infusion

Andere namen:
  • MK-3475
  • KEYTRUDA®

IV infusion or oral tablets

Actieve vergelijker: SOC (Per Parent Study)

Participants receive the dose matched non-pembrolizumab SOC treatment (e.g. chemotherapy) they were receiving as per parent study protocol.

IV infusion or oral tablets

Experimenteel: Lenvatinib 20 mg

Participants with body weight (BW)>60kg receive Lenvatinib 20mg orally once daily on a 21 or 42 day cycle. It is taken 0-4 hours after completion of pembrolizumabd administration in the clinic on cycle 1 day 1(C1D1), C2D1, C3D1, etc. Taken at home on all other days.

Oral capsules

Experimenteel: Lenvatinib 24 mg

Participants with body weight (BW)>60 kg receive Lenvatinib 24 mg orally once daily on a 21 or 42 day cycle. It is taken 0-4 hours after completion of pembrolizumabd administration in the clinic on cycle 1 day 1(C1D1), C2D1, C3D1, etc. Taken at home on all other days.

Oral capsules

Experimenteel: Lenvatinib 12 mg

Participants with body weight (BW)>60 kg receive Lenvatinib 12 mg orally once daily on a 21 or 42 day cycle. It is taken 0-4 hours after completion of pembrolizumabd administration in the clinic on cycle 1 day 1(C1D1), C2D1, C3D1, etc. Taken at home on all other days.

Oral capsules

Experimenteel: Lenvatinib 8 mg

Participants with body weight (BW)<60 kg receive Lenvatinib 8 mg orally once daily on a 21 or 42 day cycle. It is taken 0-4 hours after completion of pembrolizumabd administration in the clinic on cycle 1 day 1(C1D1), C2D1, C3D1, etc. Taken at home on all other days.

Oral capsules

Experimenteel: Lenvatinib 2mg

Participants with body weight (BW)<60 kg receive Lenvatinib 2 mg orally once daily on a 21 or 42 day cycle. It is taken 0-4 hours after completion of pembrolizumab administration in the clinic on cycle 1 day 1(C1D1), C2D1, C3D1, etc. Taken at home on all other days.

Oral capsules

Experimenteel: Olaparib 300mg

Participants receive Olaparib 300 mg orally twice daily (BID) until disease progression or toxicity prohibits its administration.

300mg or 250mg or 100mg oral tablers

Andere namen:
  • Lynparza
Experimenteel: Olaparib 250mg

Participants receive Olaparib 250 mg orally twice daily (BID) until disease progression or toxicity prohibits its administration.

300mg or 250mg or 100mg oral tablers

Andere namen:
  • Lynparza
Experimenteel: Olaparib 100mg

Participants receive Olaparib 100 mg orally twice daily (BID) until disease progression or toxicity prohibits its administration.

300mg or 250mg or 100mg oral tablers

Andere namen:
  • Lynparza
Experimenteel: MK-4280 800mg

Participants receive MK-4280 800mg as IV infusion every 3 weeks (Q3W) and may continue study therapy until study treatment completion or may transition to pembrolizumab to complete their treatment.

IV Infusion

Andere namen:
  • Favezelimab
Experimenteel: MK-4280A

Participants receive MK-4280A (800mg favezelimab + 200mg pembrolizumab) as IV infusion every 3 weeks (Q3W) and may continue study therapy until study treatment completion or may transition to pembrolizumab to complete their treatment.

800mg favezelimab + 200mg pembrolizumab IV Infusion

Experimenteel: Pembrolizumab (+) Berahyaluronidase alfa 395 mg

Participants receive 395 mg of a fixed-dose formulation of pembrolizumab and berahyaluronidase alfa via subcutaneous (SC) administration on Day 1 of each 3-week cycle for up to 35 administrations.

395 mg or 790 mg SC administration

Andere namen:
  • MK-3475A
Experimenteel: Pembrolizumab (+) Berahyaluronidase alfa 790 mg

Participants receive 790 mg of a fixed-dose formulation of pembrolizumab and berahyaluronidase alfa via SC administration on Day 1 of each 6-week cycle for up to 35 administrations.

395 mg or 790 mg SC administration

Andere namen:
  • MK-3475A

Wat meet het onderzoek?

Primaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Overall Survival (OS)
Tijdsspanne: Up to approximately 10 years

OS is defined as the time from randomization or start of study treatment for non-randomized participants (on the parent study) to death due to any cause. Participants without documented death at the time of analysis will be censored at the date of the last known to be alive.

Up to approximately 10 years

Secundaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Modified Progression Free Survival (PFS) Per Evaluation Criteria Used in the Parent Trial
Tijdsspanne: Up to approximately 10 years

Modified PFS is defined as the time from randomization or start of study treatment for nonrandomized participants (on the parent study or this study) to the first documented disease progression per the evaluation criteria used in the parent study based on investigator assessment or death due to any cause, whichever occurs first. The censoring rule is modified that participants without modified PFS events at the time of the analysis will be censored at the date of last known to be alive.

Up to approximately 10 years
Modified Event Free Survival (EFS) Per Evaluation Criteria Used in the Parent Trial
Tijdsspanne: Up to approximately 10 years

Modified EFS is defined as the time from randomization to disease progression that precludes surgery, local or distant recurrence, or death due to any cause, whichever occurs first. The censoring rule is modified that participants without documented modified EFS events at the time of the analysis will be censored at the date of last known to be alive.

Up to approximately 10 years
Number of Participants Who Experience Serious Adverse Events (SAEs)
Tijdsspanne: Up to approximately 42 months (Up to 90 days after last dose of study treatment)

A SAE is defined as any untoward medical occurrence that, at any dose: Results in death, Is life-threatening, Requires inpatient hospitalization or prolongation of existing hospitalization, Results in persistent or significant disability/incapacity or Is a congenital anomaly/birth defect. The number of participants who experience a SAE in this study will be presented.

Up to approximately 42 months (Up to 90 days after last dose of study treatment)
Number of Participants Who Experience Adverse Events of Special Interest (AEOSI)
Tijdsspanne: Up to approximately 40 months (Up to 30 days after last dose of study treatment)

AEOSI for this study include selected preferred terms from Medical Dictionary for Regulatory Activities (MedDRA) version 20.1 for the following higher-level terms: Pneumonitis, Colitis, Hepatitis, Nephritis, Adrenal Insufficiency, Hypophysitis, Hyperthyroidism, Hypothyroidism, Thyroiditis, Type 1 Diabetes Mellitus, Severe Skin Reactions Including Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): or If grade 3 or higher, Uveitis, Pancreatitis, Myositis, Guillain-Barre Syndrome, Myocarditis, Encephalitis, Sarcoidosis, Infusion Reactions and Myasthenic Syndrome. The number of participants who experience an AEOSI in this study will be presented.

Up to approximately 40 months (Up to 30 days after last dose of study treatment)
Number of Participants Who Experience Clinically Significant Adverse Events (CSAE)
Tijdsspanne: Up to approximately 40 months (Up to 30 days after last dose of study treatment)

CSAE are AEs associated with lenvatinib treatment and include selected preferred terms from the lenvatinib CSAE preferred term list document. The number of participants who experience an CSAE in this study will be presented.

Up to approximately 40 months (Up to 30 days after last dose of study treatment)
Number of Participants Who Experience Events of Clinical Interest (ECI)
Tijdsspanne: Up to approximately 40 months (Up to 30 days after last dose of study treatment)

ECIs for this study include: 1) An overdose of Sponsor's product, that is not associated with clinical symptoms or abnormal laboratory results or 2) An elevated aspartate aminotransferase (AST) or alanine aminotransferase (ALT) lab value that is ≥3X the upper limit of normal (ULN) and an elevated total bilirubin lab value that is ≥2X ULN and, at the same time, an alkaline phosphatase lab value that is <2X ULN, as determined by way of protocol-specified laboratory testing or unscheduled laboratory testing. The number of participants who experience an ECI in this study will be presented.

Up to approximately 40 months (Up to 30 days after last dose of study treatment)
Number of Participants Who Discontinue Study Treatment Due to an AE
Tijdsspanne: Up to approximately 39 months

An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of a study intervention. The number of participants who discontinue study treatment due to an AE will be presented.

Up to approximately 39 months

Medewerkers en onderzoekers

Hier vindt u mensen en organisaties die betrokken zijn bij dit onderzoek.

Onderzoekers

  • Studie directeur: Medical Director, Merck Sharp & Dohme LLC

Publicaties en nuttige links

De persoon die verantwoordelijk is voor het invoeren van informatie over het onderzoek stelt deze publicaties vrijwillig ter beschikking. Dit kan gaan over alles wat met het onderzoek te maken heeft.

Studie record data

Deze datums volgen de voortgang van het onderzoeksdossier en de samenvatting van de ingediende resultaten bij ClinicalTrials.gov. Studieverslagen en gerapporteerde resultaten worden beoordeeld door de National Library of Medicine (NLM) om er zeker van te zijn dat ze voldoen aan specifieke kwaliteitscontrolenormen voordat ze op de openbare website worden geplaatst.

Bestudeer belangrijke data

Studie start (Werkelijk)

21 augustus 2018

Primaire voltooiing (Geschat)

4 augustus 2043

Studie voltooiing (Geschat)

4 augustus 2043

Studieregistratiedata

Eerst ingediend

29 maart 2018

Eerst ingediend dat voldeed aan de QC-criteria

29 maart 2018

Eerst geplaatst (Werkelijk)

3 april 2018

Updates van studierecords

Laatste update geplaatst (Werkelijk)

29 oktober 2026

Laatste update ingediend die voldeed aan QC-criteria

28 oktober 2026

Laatst geverifieerd

1 oktober 2026

Meer informatie

Termen gerelateerd aan deze studie

Trefwoorden

Andere studie-ID-nummers

  • 3475-587
  • 2017 (Subsidie/contract van de Amerikaanse NIH)
  • MK-3475-587 (Andere identificatie: MSD)
  • KEYNOTE-587 (Andere identificatie: MSD)
  • 195006 (Register-ID: JAPIC-CTI)
  • PHRR210209-002881 (Register-ID: PHRR)
  • 2017-004417-42 (EudraCT-nummer)
  • jRCT2080224921 (Andere identificatie: jRCT)
  • 2022-501254-10-00 (Register-ID: EU CT)
  • U1111-1274-2274 (Register-ID: UTN)

Plan Individuele Deelnemersgegevens (IPD)

Bent u van plan om gegevens van individuele deelnemers (IPD) te delen?

JA

Beschrijving IPD-plan

https://trialstransparency.msdclinicaltrials.com/pdf/ProcedureAccessClinicalTrialData.pdf

Informatie over medicijnen en apparaten, studiedocumenten

Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel

Ja

Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct

Nee

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