Deze pagina is automatisch vertaald en de nauwkeurigheid van de vertaling kan niet worden gegarandeerd. Raadpleeg de Engelse versie voor een brontekst.

Study on Intervention Effect of Heat-related Health Risk Early Warning Digital Technology for School-age Children

9 juni 2026 bijgewerkt door: Tiantian Li, Centers for Disease Control and Prevention, China
This cluster randomized trial is conducted in Beijing primary schools to evaluate the efficacy of a WeChat mini-program-based high-temperature early warning intervention on the physical and cognitive health of school-age children. Six participating schools are randomly assigned to two parallel groups. The intervention group receives tiered heat alerts and guided self-health monitoring via the mini-program. The control group follows standard daily school and family routines, with no dedicated digital high-temperature early-warning intervention. The primary outcome is children's executive function after a 2.5-month follow-up. A range of secondary indicators related to physical status, mental health and health behaviors are assessed concurrently to quantify the intervention's benefits in mitigating adverse health outcomes caused by high temperatures.

Studie Overzicht

Toestand

Nog niet aan het werven

Conditie

Interventie / Behandeling

Gedetailleerde beschrijving

This pilot study is conducted in Beijing, with 6 primary schools selected as research sites. A stratified cluster randomized controlled design is adopted, with schools as the unit of randomization. Eligible primary schools are randomly assigned to the intervention group and the control group, with 3 schools in each group.

A total of 5 Wisconsin Card Sorting Tests (WCST), 2 health examinations, 2 children's high-temperature protection themed drawing activities, and 5 mini-program questionnaire surveys will be conducted in this study.

The intervention group receives a digital intervention of high-temperature health risk early warning. The research team uses a WeChat mini-program to release corresponding high-temperature health risk level information, health tips, protection science popularization information and other early warning content when the high-temperature health risk level reaches yellow, orange or red, and simultaneously pushes them to head teachers and parents.

The monitoring and survey schedule for the intervention group during the study period is as follows: at baseline and endpoint, unified offline WCST and health examinations will be conducted for children once each, accompanied by one online mini-program questionnaire survey each time. One children's high-temperature protection themed drawing activity will be organized at baseline and at the end of the 3rd month after the intervention, and the works will be uploaded to the mini-program for check-in. At the end of the 1st, 2nd and 3rd months after the intervention, one online follow-up questionnaire and WCST will be completed each month, together with check-in. Meanwhile, blood pressure will be monitored once a week, and daily blood pressure monitoring and check-in will be carried out after each high-temperature health risk early warning release. In addition, after the release of high-temperature health risk early warnings, the intervention group is required to complete check-in for reading and transmitting early warning information, health tips and protection science popularization content, as well as online mini-program surveys on children's awareness of high-temperature health risk early warning information and short-term behavioral patterns. The above WCST and questionnaire surveys will be completed by children with parental assistance; blood pressure monitoring and check-in are the responsibility of head teachers during non-summer vacations and parents during summer vacations.

The control group does not receive the high-temperature health risk early warning intervention and will only complete the corresponding WCST, health examinations, questionnaire surveys and blood pressure monitoring.

Studietype

Ingrijpend

Inschrijving (Geschat)

200

Fase

  • Niet toepasbaar

Contacten en locaties

In dit gedeelte vindt u de contactgegevens van degenen die het onderzoek uitvoeren en informatie over waar dit onderzoek wordt uitgevoerd.

Studiecontact

Studie Contact Back-up

Deelname Criteria

Onderzoekers zoeken naar mensen die aan een bepaalde beschrijving voldoen, de zogenaamde geschiktheidscriteria. Enkele voorbeelden van deze criteria zijn iemands algemene gezondheidstoestand of eerdere behandelingen.

Geschiktheidscriteria

Leeftijden die in aanmerking komen voor studie

  • Kind

Accepteert gezonde vrijwilligers

Ja

Beschrijving

School inclusion criteria

  1. Willing to participate in the study.
  2. Possess adequate facilities and qualified teaching staff.
  3. The school and teachers maintain good cooperation.
  4. Class size is no less than 35 students.
  5. All participating classrooms are equipped with air conditioners.

Participant inclusion criteria

  1. Fourth-grade primary school students aged 9 to 11, of all genders.
  2. Voluntary participation by students and their parents, good compliance, and signed informed consent.
  3. At least one adult family member has an internet-enabled mobile device.
  4. Good general health with no history of severe physical or mental disorders.
  5. Local permanent residents with a residency of no less than 6 months.

Participant exclusion criteria

  1. Participants who are unable or refuse to complete required examinations.
  2. Students receiving psychological or psychiatric treatment that may confound the study results.
  3. Those currently enrolled in other interventional clinical studies that may affect outcome assessment.
  4. Any other conditions deemed ineligible by the research team. Any participant meeting any of the above exclusion criteria will be excluded from the study.

Studie plan

Dit gedeelte bevat details van het studieplan, inclusief hoe de studie is opgezet en wat de studie meet.

Hoe is de studie opgezet?

Ontwerpdetails

  • Primair doel: Preventie
  • Toewijzing: Gerandomiseerd
  • Interventioneel model: Parallelle opdracht
  • Masker: Dubbele

Wapens en interventies

Deelnemersgroep / Arm
Interventie / Behandeling
Geen tussenkomst: Control Group
The control group does not receive the mini-program-based high-temperature health risk early warning intervention.
Experimenteel: WeChat Mini-program Heat Health Early Warning Intervention Group
Participants receive tiered yellow, orange and red heat risk alerts and heat protection guidance via the WeChat Mini Program once alerts are issued due to high temperatures. Teachers and parents share health promotion tips with enrolled children. Mandatory mini-program check-ins and routine health monitoring are implemented throughout the 2.5-month intervention.
Ander: WeChat Mini-program Based Heat Health Risk Early Warning Intervention
This study implements a digital early warning intervention targeting children's high-temperature health risks. During the intervention period, when the high-temperature health risk level reaches yellow, orange or red, relevant risk information, health tips and heat protection education materials are released to parents and head teachers via the WeChat mini-program. Parents or teachers pass on the warning information to participating children. During non-summer periods, Beijing's high-temperature early warning information is pushed to head teachers and parents via the WeChat mini-program; during summer vacation, location-specific early warning information is sent to parents. All recipients are required to pass on the information to children promptly upon receipt.

Wat meet het onderzoek?

Primaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
The primary outcome is the comprehensive total score of children's executive function constructed based on the Wisconsin Card Sorting Test (WCST)
Tijdsspanne: at 2.5 months of intervention.
The only primary outcome of this study is the composite score of cognitive executive function derived from the Wisconsin Card Sorting Test (WCST) via the TOPSIS method. All WCST absolute indicators and sub-dimensions are sub-indicators instead of independent outcomes. The WCST indicators are grouped into three sub-dimensions: conceptual thinking (Total Correct, Total Errors, Nonperseverative Errors, Conceptual Level Responses, Categories Completed), perseveration (Perseverative Responses, Perseverative Errors), and set maintenance (Failure to Maintain Set). Negative indicators are converted using the formula (x' = Max(x) - x). After Z-score normalization, the decision matrix is established, positive and negative ideal solutions are identified, and Euclidean distances and relative closeness are computed. The resulting relative closeness value is taken as the final composite score of cognitive executive function, the single primary outcome of this study.
at 2.5 months of intervention.

Secundaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Systolic Blood Pressure
Tijdsspanne: at 2.5 months of intervention
Systolic Blood Pressure measured in mmHg
at 2.5 months of intervention
Diastolic Blood Pressure
Tijdsspanne: at 2.5 months of intervention
Diastolic blood pressure measured in mmHg
at 2.5 months of intervention
Heart Rate
Tijdsspanne: at 2.5 months of intervention
Resting heart rate measured in beats per minute (bpm)
at 2.5 months of intervention
Forced Expiratory Volume in 1 second (FEV1)
Tijdsspanne: at 2.5 months of intervention
Pulmonary function indicator measured in liters (L)
at 2.5 months of intervention
Forced Vital Capacity (FVC)
Tijdsspanne: at 2.5 months of intervention
Pulmonary function indicator measured in liters (L)
at 2.5 months of intervention
Peak Expiratory Flow (PEF)
Tijdsspanne: at 2.5 months of intervention
Pulmonary function indicator measured in liters per second (L/s)
at 2.5 months of intervention
Forced Expiratory Flow 25-75% (FEF25-75%)
Tijdsspanne: at 2.5 months of intervention
Mid-expiratory flow measured in liters per second (L/s)
at 2.5 months of intervention
Fractional Exhaled Nitric Oxide (FeNO50)
Tijdsspanne: at 2.5 months of intervention
Exhaled nitric oxide level at 50 mL/s flow rate, measured in parts per billion (ppb)
at 2.5 months of intervention
Fractional Exhaled Nitric Oxide (FeNO200)
Tijdsspanne: at 2.5 months of intervention
Exhaled nitric oxide level at 200 mL/s flow rate, measured in parts per billion (ppb)
at 2.5 months of intervention
Calcium Nitric Oxide (CaNO)
Tijdsspanne: at 2.5 months of intervention
Airway nitric oxide parameter measured in ppb
at 2.5 months of intervention
Fractional Expiratory Carbon Monoxide (FeCO)
Tijdsspanne: at 2.5 months of intervention
Exhaled carbon monoxide level measured in parts per million (ppm)
at 2.5 months of intervention
Body Fat Percentage
Tijdsspanne: at 2.5 months of intervention
Body fat percentage measured by bioelectrical impedance analysis
at 2.5 months of intervention
Total Body Water
Tijdsspanne: at 2.5 months of intervention
Total body water measured in liters (L)
at 2.5 months of intervention
Inorganic Salts
Tijdsspanne: at 2.5 months of intervention
Inorganic salt content measured in kilograms (kg)
at 2.5 months of intervention
Basal Metabolic Rate (BMR)
Tijdsspanne: at 2.5 months of intervention
Basal metabolic rate measured in kilocalories per day (kcal/day)
at 2.5 months of intervention
Body Weight
Tijdsspanne: at 2.5 months of intervention
Body weight measured in kilograms (kg)
at 2.5 months of intervention
High-Temperature Health KAP Score
Tijdsspanne: at 2.5 months of intervention
Knowledge, Attitude, and Practice (KAP) score on high-temperature health
at 2.5 months of intervention
High-Temperature Health Cognition and Protection Behavior Drawing Score
Tijdsspanne: at 2.5 months of intervention
Drawing-based score of children's cognition and protective behaviors for high-temperature health
at 2.5 months of intervention
Short-Term Behavioral Pattern Score
Tijdsspanne: at 2.5 months of intervention
Score of children's short-term behavioral patterns related to heat health
at 2.5 months of intervention
SAS Anxiety Scale Score
Tijdsspanne: at 2.5 months of intervention
Self-rating Anxiety Scale (SAS) score for children's anxiety symptoms
at 2.5 months of intervention
CDI Children's Depression Scale Score
Tijdsspanne: at 2.5 months of intervention
Children's Depression Inventory (CDI) score for depressive symptoms
at 2.5 months of intervention
SGRQ Respiratory Symptom Scale Score
Tijdsspanne: at 2.5 months of intervention
St. George's Respiratory Questionnaire (SGRQ) score for respiratory symptoms
at 2.5 months of intervention
School Absenteeism Days
Tijdsspanne: at 2.5 months of intervention
Number of school absenteeism days during the study period
at 2.5 months of intervention
Academic Performance
Tijdsspanne: at 2.5 months of intervention
Scores of children's academic examinations
at 2.5 months of intervention
Heat-Related Illness Incidence
Tijdsspanne: at 2.5 months of intervention
Occurrence frequency of heat-related illnesses in children
at 2.5 months of intervention
Gastrointestinal Diseases Incidence
Tijdsspanne: at 2.5 months of intervention
Occurrence frequency of gastrointestinal diseases in children
at 2.5 months of intervention
Respiratory Diseases Incidence
Tijdsspanne: at 2.5 months of intervention
Occurrence frequency of respiratory diseases in children
at 2.5 months of intervention
Allergies Incidence
Tijdsspanne: at 2.5 months of intervention
Occurrence frequency of allergies in children
at 2.5 months of intervention
Accidental Injuries Incidence
Tijdsspanne: at 2.5 months of intervention
Occurrence frequency of accidental injuries in children
at 2.5 months of intervention
Early Warning Information Check-in Rate
Tijdsspanne: at 2.5 months of intervention
Check-in rate of early warning information received by the intervention group
at 2.5 months of intervention

Medewerkers en onderzoekers

Hier vindt u mensen en organisaties die betrokken zijn bij dit onderzoek.

Sponsor

Centers for Disease Control and Prevention, China

Publicaties en nuttige links

De persoon die verantwoordelijk is voor het invoeren van informatie over het onderzoek stelt deze publicaties vrijwillig ter beschikking. Dit kan gaan over alles wat met het onderzoek te maken heeft.

Algemene publicaties

Studie record data

Deze datums volgen de voortgang van het onderzoeksdossier en de samenvatting van de ingediende resultaten bij ClinicalTrials.gov. Studieverslagen en gerapporteerde resultaten worden beoordeeld door de National Library of Medicine (NLM) om er zeker van te zijn dat ze voldoen aan specifieke kwaliteitscontrolenormen voordat ze op de openbare website worden geplaatst.

Bestudeer belangrijke data

Studie start (Geschat)

1 juni 2026

Primaire voltooiing (Geschat)

1 september 2026

Studie voltooiing (Geschat)

1 september 2026

Studieregistratiedata

Eerst ingediend

3 juni 2026

Eerst ingediend dat voldeed aan de QC-criteria

9 juni 2026

Eerst geplaatst (Werkelijk)

11 juni 2026

Updates van studierecords

Laatste update geplaatst (Werkelijk)

11 juni 2026

Laatste update ingediend die voldeed aan QC-criteria

9 juni 2026

Laatst geverifieerd

1 juni 2026

Meer informatie

Termen gerelateerd aan deze studie

Trefwoorden

Aanvullende relevante MeSH-voorwaarden

Andere studie-ID-nummers

  • NIEH202643

Plan Individuele Deelnemersgegevens (IPD)

Bent u van plan om gegevens van individuele deelnemers (IPD) te delen?

ONBESLIST

Informatie over medicijnen en apparaten, studiedocumenten

Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel

Nee

Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct

Nee

Deze informatie is zonder wijzigingen rechtstreeks van de website clinicaltrials.gov gehaald. Als u verzoeken heeft om uw onderzoeksgegevens te wijzigen, te verwijderen of bij te werken, neem dan contact op met register@clinicaltrials.gov. Zodra er een wijziging wordt doorgevoerd op clinicaltrials.gov, wordt deze ook automatisch bijgewerkt op onze website .

Klinische onderzoeken op Hart-en vaatziekten

Zoek naar vergelijkbare onderzoeken

Sponsors en medewerkers

Medische omstandigheden

Geneesmiddelinterventies

CROs by country

CROs in Congo

Voorwaarden

Zeldzame ziekten

Geneesmiddelinterventies

Voedingssupplementen

Sponsor / medewerkers

Locaties

Abonneren