Deze pagina is automatisch vertaald en de nauwkeurigheid van de vertaling kan niet worden gegarandeerd. Raadpleeg de Engelse versie voor een brontekst.

Effect of Adapted Physical Activity on Emotion Regulation in People With Depressive Disorders (REAPAD)

21 augustus 2026 bijgewerkt door: Centre Hospitalier Georges Mazurelle

Impact d'un Programme d'activité Physique adaptée Sur la régulation Des émotions de Personnes Souffrant de Troubles dépressifs, en Sortie d'Hospitalisation : étude REAPAD

Depression is associated with difficulties in emotion regulation. Adapted physical activity (APA) may help improve emotional regulation in people with depressive disorders.

The REAPAD study evaluates the effects of an adapted physical activity program on emotion regulation in adults with depressive disorders following psychiatric hospitalization. Participants were randomly assigned to one of two APA programs: a standard adapted physical activity program or a combined adapted physical activity program including activities specifically targeting emotional regulation.

Emotion regulation is assessed using the Cognitive Emotion Regulation Questionnaire (CERQ). The study also evaluates depressive symptoms, anxiety, self-esteem, physical activity, physical condition, and other psychological and physical outcomes.

Studie Overzicht

Toestand

Voltooid

Conditie

Interventie / Behandeling

Studietype

Ingrijpend

Inschrijving (Werkelijk)

45

Fase

  • Niet toepasbaar

Contacten en locaties

In dit gedeelte vindt u de contactgegevens van degenen die het onderzoek uitvoeren en informatie over waar dit onderzoek wordt uitgevoerd.

Studie Locaties

  • Frankrijk
    • Vendée
      • La Roche-sur-Yon, Vendée, Frankrijk, 85 000
        • EPSM de Vendée - Centre Hospitalier Georges Mazurelle

Deelname Criteria

Onderzoekers zoeken naar mensen die aan een bepaalde beschrijving voldoen, de zogenaamde geschiktheidscriteria. Enkele voorbeelden van deze criteria zijn iemands algemene gezondheidstoestand of eerdere behandelingen.

Geschiktheidscriteria

Leeftijden die in aanmerking komen voor studie

  • Volwassen
  • Oudere volwassene

Accepteert gezonde vrijwilligers

Nee

Beschrijving

Inclusion Criteria:

  • Age over 18 years
  • Unipolar or bipolar depressive disorder
  • Discharged from full hospitalization, up to three weeks after discharge
  • Able to provide free and informed consent
  • Not participating in any other research

Exclusion Criteria:

  • High suicidal risk, at the investigator's discretion
  • Medical contraindication to any physical activity
  • Motor, psychological, or intellectual disability, or other medical condition, at the investigator's discretion, preventing full participation in the study
  • Severe addictive disorder impeding participation in the study
  • Psychotic disorder
  • Pregnancy or breastfeeding
  • Any circumstances rendering the participant unable to understand the nature, purpose, or consequences of the trial
  • Under legal protection (guardianship or trusteeship)
  • No social security coverage

Studie plan

Dit gedeelte bevat details van het studieplan, inclusief hoe de studie is opgezet en wat de studie meet.

Hoe is de studie opgezet?

Ontwerpdetails

  • Primair doel: Behandeling
  • Toewijzing: Gerandomiseerd
  • Interventioneel model: Parallelle opdracht
  • Masker: Geen (open label)

Wapens en interventies

Deelnemersgroep / Arm
Interventie / Behandeling
Actieve vergelijker: Classical Adapted Physical Activity
Gedragsmatig: Classical Adapted Physical Activity Program
Participants received an individualized, moderate-intensity adapted physical activity program consisting of 8 sessions over 6 weeks, with at least one session per week. The program included aerobic training (step-based exercises, lateral stepping and locomotor circuit tasks), lower-limb resistance training (chair stands, step-ups, lateral stepping and lunges), and agility and coordination exercises (agility ladder drills and motor circuit tasks). Session duration progressively increased from 25 minutes for sessions 1 and 8 to 30, 35 and 40 minutes for the intermediate sessions. Each session included a 5-minute warm-up and muscular flexibility period and a 10-minute cool-down period.
Experimenteel: Combined Adapted Physical Activity Program
Gedragsmatig: Adapted Physical Activity Program
Participants received an individualized, moderate-intensity adapted physical activity program consisting of 8 sessions over 6 weeks, with at least one session per week. The program included aerobic training, lower-limb resistance training, and agility and coordination exercises. In addition, cognitive and emotional training tasks were integrated into the physical activity sessions. Cognitive tasks included short-term memory activities, verbal fluency dual tasks and cognitive flexibility exercises. Emotional tasks included identifying, recognizing and expressing emotions using images and photographs of facial expressions. These cognitive and emotional tasks were incorporated during exercises and rest periods throughout the program.

Wat meet het onderzoek?

Primaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Change in emotion regulation strategies assessed by the Cognitive Emotion Regulation Questionnaire (CERQ
Tijdsspanne: Baseline (T0), immediately after completion of the 6-week intervention (T1), and 6 weeks after the end of the intervention (T2)
Emotion regulation strategies are assessed using the Cognitive Emotion Regulation Questionnaire (CERQ), a 36-item self-administered questionnaire comprising nine subscales. Items are rated from 1 (almost never) to 5 (almost always), providing scores for adaptive and maladaptive cognitive emotion regulation strategies
Baseline (T0), immediately after completion of the 6-week intervention (T1), and 6 weeks after the end of the intervention (T2)

Secundaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Change in Depressive Symptom Severity Assessed by the Montgomery-Åsberg Depression Rating Scale (MADRS
Tijdsspanne: Baseline (T0), immediately after completion of the 6-week intervention (T1), and 6 weeks after the end of the intervention (T2)
Depressive symptom severity is assessed using the Montgomery-Åsberg Depression Rating Scale (MADRS). The scale consists of 10 items assessing depressive symptoms, each rated from 0 to 6. The total score ranges from 0 to 60, with higher scores indicating greater severity of depressive symptoms.
Baseline (T0), immediately after completion of the 6-week intervention (T1), and 6 weeks after the end of the intervention (T2)
Change in Cognitive Flexibility Assessed by the Trail Making Test (TMT)
Tijdsspanne: Baseline (T0), immediately after completion of the 6-week intervention (T1), and 6 weeks after the end of the intervention (T2)
Cognitive functioning is assessed using the Trail Making Test (TMT). The test includes Part A and Part B. Performance is assessed using the time required to complete each part, with longer completion times indicating poorer performance.
Baseline (T0), immediately after completion of the 6-week intervention (T1), and 6 weeks after the end of the intervention (T2)
Change in Subjective Vitality Assessed by the Subjective Vitality Scale
Tijdsspanne: Baseline (T0), immediately after completion of the 6-week intervention (T1), and 6 weeks after the end of the intervention (T2)
Subjective vitality is assessed using the Subjective Vitality Scale. The scale consists of 5 items rated from 1 to 7 and assesses the participant's subjective experience of physical and psychological energy and vitality. Higher scores indicate greater subjective vitality
Baseline (T0), immediately after completion of the 6-week intervention (T1), and 6 weeks after the end of the intervention (T2)
Change in Mood States Assessed by the Profile of Mood States (POMS-F)
Tijdsspanne: Immediately before and immediately after each adapted physical activity session
Mood states are assessed using the French version of the Profile of Mood States (POMS-F), a 65-item self-administered questionnaire. The questionnaire assesses seven transient and fluctuating mood dimensions: tension-anxiety, anger-hostility, confusion-bewilderment, depression-dejection, fatigue-inertia, vigor-activity, and interpersonal relations. Items are rated on a 5-point Likert scale. An overall psychological distress score is calculated by summing the tension-anxiety, anger-hostility, confusion-bewilderment, depression-dejection, and fatigue-inertia scores and subtracting the vigor-activity score. Higher psychological distress scores indicate greater mood disturbance. Mood state is assessed using the French version of the Profile of Mood States (POMS-F). The POMS-F consists of 65 items rated from 0 (not at all) to 4 (extremely). The Global Score is calculated as the sum of Anxiety-Tension, Anger-Hostility, Confusion-Bewilderment, Depression-Dejection, and Fatigue-Inertia scores
Immediately before and immediately after each adapted physical activity session

Medewerkers en onderzoekers

Hier vindt u mensen en organisaties die betrokken zijn bij dit onderzoek.

Sponsor

Centre Hospitalier Georges Mazurelle

Publicaties en nuttige links

De persoon die verantwoordelijk is voor het invoeren van informatie over het onderzoek stelt deze publicaties vrijwillig ter beschikking. Dit kan gaan over alles wat met het onderzoek te maken heeft.

Algemene publicaties

  • Longuechaud C, Videau Villeneuve F, Bulteau F, Valot I, Douet M, Bulteau S, Deschamps T, Sauvaget A. The effect of adapted physical activity programs on the regulation of emotions in people suffering from major depressive disorders after hospital discharge: REAPAD study protocol. Minerva Psychiatry. 2026;67(2):82. doi:10.23736/S2724-6612.26.02669-2.

Studie record data

Deze datums volgen de voortgang van het onderzoeksdossier en de samenvatting van de ingediende resultaten bij ClinicalTrials.gov. Studieverslagen en gerapporteerde resultaten worden beoordeeld door de National Library of Medicine (NLM) om er zeker van te zijn dat ze voldoen aan specifieke kwaliteitscontrolenormen voordat ze op de openbare website worden geplaatst.

Bestudeer belangrijke data

Studie start (Werkelijk)

10 februari 2023

Primaire voltooiing (Werkelijk)

30 april 2026

Studie voltooiing (Werkelijk)

30 april 2026

Studieregistratiedata

Eerst ingediend

19 augustus 2026

Eerst ingediend dat voldeed aan de QC-criteria

19 augustus 2026

Eerst geplaatst (Werkelijk)

21 augustus 2026

Updates van studierecords

Laatste update geplaatst (Werkelijk)

24 augustus 2026

Laatste update ingediend die voldeed aan QC-criteria

21 augustus 2026

Laatst geverifieerd

1 augustus 2026

Meer informatie

Termen gerelateerd aan deze studie

Aanvullende relevante MeSH-voorwaarden

Andere studie-ID-nummers

  • 2022-A02099-34

Plan Individuele Deelnemersgegevens (IPD)

Bent u van plan om gegevens van individuele deelnemers (IPD) te delen?

NEE

Informatie over medicijnen en apparaten, studiedocumenten

Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel

Nee

Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct

Nee

Deze informatie is zonder wijzigingen rechtstreeks van de website clinicaltrials.gov gehaald. Als u verzoeken heeft om uw onderzoeksgegevens te wijzigen, te verwijderen of bij te werken, neem dan contact op met register@clinicaltrials.gov. Zodra er een wijziging wordt doorgevoerd op clinicaltrials.gov, wordt deze ook automatisch bijgewerkt op onze website .

Abonneren