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Family TIME: A Family-focused Nursing Intervention for Adults Receiving Haemodialysis and Their Families

31 augustus 2026 bijgewerkt door: University of Southern Denmark

Family TIME: Protocol for a Randomised Mixed-methods Feasibility Study of a Family-focused Nursing Intervention for Adults Receiving Haemodialysis and Their Families

The goal of this clinical trial is to evaluate whether a structured family conversation intervention can be delivered in a feasible and acceptable way to adults living with chronic kidney disease (CKD) and their family members. The study will also explore whether the intervention and study procedures are suitable for a future larger clinical trial.

The main questions it aims to answer are:

Can adults with CKD and their family members be successfully recruited, enrolled, and retained throughout the study? Is the Family Time intervention acceptable and practical for patients, family members, and healthcare professionals? Are the study procedures and selected questionnaires appropriate for evaluating a future larger trial? Does the intervention show potential to support family functioning and well-being?

Researchers will compare the Family Time intervention plus usual care with usual care alone.

Participants will:

Complete questionnaires before and after the study period. Be allocated to either the Family Time intervention or usual care. If allocated to the intervention group, participate in three structured family conversations over approximately 8 weeks, with the option of one additional follow-up conversation.

If allocated to the intervention group, be invited to take part in an interview about their experiences after completing the intervention.

Studie Overzicht

Toestand

Nog niet aan het werven

Conditie

Interventie / Behandeling

Gedetailleerde beschrijving

Adults living with chronic kidney disease (CKD) experience substantial physical, emotional, and social challenges that extend beyond the individual and influence everyday family life. Family members frequently take on important supportive roles while simultaneously experiencing changes in family routines, responsibilities, communication, and well-being. Although family involvement is recognised as an important component of person-centred CKD care, structured family-focused interventions remain limited, and evidence supporting their implementation in routine nephrology practice is scarce.

This study aims to evaluate the feasibility and acceptability of Family Time, a nurse-led family-focused intervention developed to support communication, shared understanding, and relational well-being among adults living with CKD and their families. The intervention has been developed following the Medical Research Council (MRC) framework for developing and evaluating complex interventions and informed by evidence synthesis, qualitative research, stakeholder workshops, and patient and family involvement.

A mixed-methods randomised feasibility trial will be conducted at two in-centre haemodialysis units in Denmark. Adults receiving in-centre haemodialysis and at least one participating family member will be allocated to either the Family Time intervention plus usual care or usual care alone. The intervention consists of three structured family conversations delivered over approximately 8 weeks, with the option of one additional follow-up conversation. Sessions are facilitated by the principal investigator and may be delivered face-to-face, online, or by telephone according to family preferences and practical circumstances.

The primary outcomes are feasibility and acceptability of the intervention and study procedures, including recruitment, retention, intervention delivery, questionnaire completion, and participant experiences. Secondary exploratory outcomes include family functioning, individual well-being, and family communication, assessed using the Iceland Expressive Family Functioning Questionnaire (ICE-EFFQ), the WHO-5 Well-Being Index, and post-intervention qualitative interviews.

The findings will inform refinement of both the intervention and study procedures and determine whether progression to a future definitive randomised controlled trial is warranted.

Studietype

Ingrijpend

Inschrijving (Geschat)

60

Fase

  • Niet toepasbaar

Contacten en locaties

In dit gedeelte vindt u de contactgegevens van degenen die het onderzoek uitvoeren en informatie over waar dit onderzoek wordt uitgevoerd.

Studiecontact

  • Naam: Jeannett A Klitgaard, Master of Science in Nursing
  • Telefoonnummer: +4540478192
  • E-mail: jekl@ucl.dk

Studie Locaties

Deelname Criteria

Onderzoekers zoeken naar mensen die aan een bepaalde beschrijving voldoen, de zogenaamde geschiktheidscriteria. Enkele voorbeelden van deze criteria zijn iemands algemene gezondheidstoestand of eerdere behandelingen.

Geschiktheidscriteria

Leeftijden die in aanmerking komen voor studie

  • Volwassen
  • Oudere volwassene

Accepteert gezonde vrijwilligers

Nee

Beschrijving

Inclusion Criteria:

  • Adult patient aged 18 years or older
  • Currently receiving in-centre haemodialysis for CKD
  • Has received in-centre haemodialysis for at least 3 months
  • Able to read, speak, and understand Danish
  • Able to provide written informed consent
  • Able to identify at least one family member willing to participate
  • Participating family member aged 18 years or older
  • Participating family member able to speak and understand Danish
  • Participating family member able to provide written informed consent

Exclusion Criteria:

  • Documented cognitive impairment preventing informed consent or participation
  • Clinically assessed as too physically or psychologically unwell to participate
  • Unable to participate in Danish
  • Currently receiving structured family therapy or another family-focused psychosocial intervention

Studie plan

Dit gedeelte bevat details van het studieplan, inclusief hoe de studie is opgezet en wat de studie meet.

Hoe is de studie opgezet?

Ontwerpdetails

  • Primair doel: Ondersteunende zorg
  • Toewijzing: Gerandomiseerd
  • Interventioneel model: Parallelle opdracht
  • Masker: Geen (open label)

Wapens en interventies

Deelnemersgroep / Arm
Interventie / Behandeling
Geen tussenkomst: Usual care
Participants allocated to the control group will receive usual care provided by the participating haemodialysis units throughout the study period.
Experimenteel: Family Time + Usual Care
Participants allocated to the intervention group will receive the Family Time intervention in addition to usual care.
Ander: Family TIME
Participants allocated to the intervention group will receive the Family Time intervention in addition to usual care. The intervention consists of three structured family conversations delivered over approximately 8 weeks, with the option of one additional follow-up session. Conversations are facilitated by the principal investigator and may be delivered face-to-face, online, or by telephone according to family preferences and practical circumstances.

Wat meet het onderzoek?

Primaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Recruitment rate
Tijdsspanne: From the first family conversation to completion of the intervention, up to 8 weeks.
Number and proportion of eligible family units recruited into the study.
From the first family conversation to completion of the intervention, up to 8 weeks.
Retention rate
Tijdsspanne: 8 weeks after baseline
Number and proportion of participants completing follow-up.
8 weeks after baseline
Intervention delivery
Tijdsspanne: From the first family conversation through completion of the intervention, up to 8 weeks.
Number and proportion of planned structured facilitated family conversations completed according to protocol.
From the first family conversation through completion of the intervention, up to 8 weeks.
Intervention acceptability
Tijdsspanne: 8 weeks after baseline
Acceptability assessed using the Danish version of the Acceptability of Intervention Measure (AIM).
8 weeks after baseline
Study procedures
Tijdsspanne: Baseline and Week 9
Questionnaire completion rate, follow-up completion and completeness of data collection procedures.
Baseline and Week 9
Implementation considerations
Tijdsspanne: Throughout the 8-week intervention period and at post-intervention interview in Week 9
Barriers and facilitators identified through intervention logs, facilitator field notes and qualitative interviews.
Throughout the 8-week intervention period and at post-intervention interview in Week 9

Secundaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Family functioning
Tijdsspanne: Baseline and 8 weeks after baseline.
Family functioning will be assessed using the Iceland Expressive Family Functioning Questionnaire (ICE-EFFQ), a 17-item questionnaire assessing expressive family functioning, including communication, emotional expression, collaboration and family relationships. Total scores range from 17 to 85, with higher scores indicating more positive expressive family functioning.
Baseline and 8 weeks after baseline.
Individual well-being
Tijdsspanne: Baseline and 8 weeks after baseline.
Subjective well-being will be assessed using the World Health Organization Five Well-Being Index (WHO-5). Raw scores range from 0 to 25 and are transformed to a scale from 0 to 100, with higher scores indicating greater subjective well-being.
Baseline and 8 weeks after baseline.

Medewerkers en onderzoekers

Hier vindt u mensen en organisaties die betrokken zijn bij dit onderzoek.

Sponsor

University of Southern Denmark

Medewerkers

Odense University Hospital
Griffith University

Onderzoekers

  • Studie directeur: Hanne Agerskov, Professor, Odense University Hospital

Publicaties en nuttige links

De persoon die verantwoordelijk is voor het invoeren van informatie over het onderzoek stelt deze publicaties vrijwillig ter beschikking. Dit kan gaan over alles wat met het onderzoek te maken heeft.

Algemene publicaties

Studie record data

Deze datums volgen de voortgang van het onderzoeksdossier en de samenvatting van de ingediende resultaten bij ClinicalTrials.gov. Studieverslagen en gerapporteerde resultaten worden beoordeeld door de National Library of Medicine (NLM) om er zeker van te zijn dat ze voldoen aan specifieke kwaliteitscontrolenormen voordat ze op de openbare website worden geplaatst.

Bestudeer belangrijke data

Studie start (Geschat)

10 augustus 2026

Primaire voltooiing (Geschat)

31 maart 2027

Studie voltooiing (Geschat)

31 mei 2027

Studieregistratiedata

Eerst ingediend

6 juli 2026

Eerst ingediend dat voldeed aan de QC-criteria

31 augustus 2026

Eerst geplaatst (Werkelijk)

3 september 2026

Updates van studierecords

Laatste update geplaatst (Werkelijk)

3 september 2026

Laatste update ingediend die voldeed aan QC-criteria

31 augustus 2026

Laatst geverifieerd

1 juli 2026

Meer informatie

Termen gerelateerd aan deze studie

Trefwoorden

Aanvullende relevante MeSH-voorwaarden

Andere studie-ID-nummers

  • Family TIME

Plan Individuele Deelnemersgegevens (IPD)

Bent u van plan om gegevens van individuele deelnemers (IPD) te delen?

JA

Beschrijving IPD-plan

De-identified individual participant data underlying the results reported in publications will be made available upon reasonable request, subject to approval by the study investigators, applicable ethical approvals, institutional policies, and Danish data protection regulations.

IPD-tijdsbestek voor delen

Beginning 3 months after publication of the primary results and continuing for 5 years.

IPD-toegangscriteria voor delen

Data will be available to qualified researchers for scientifically sound research purposes following publication of the primary study results. Requests will be reviewed by the study investigators and the data controller.

IPD delen Ondersteunend informatietype

  • LEERPROTOCOOL
  • SAP
  • ICF

Informatie over medicijnen en apparaten, studiedocumenten

Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel

Nee

Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct

Nee

Deze informatie is zonder wijzigingen rechtstreeks van de website clinicaltrials.gov gehaald. Als u verzoeken heeft om uw onderzoeksgegevens te wijzigen, te verwijderen of bij te werken, neem dan contact op met register@clinicaltrials.gov. Zodra er een wijziging wordt doorgevoerd op clinicaltrials.gov, wordt deze ook automatisch bijgewerkt op onze website .

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