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Evaluation of Brain MRI and Clinical Characteristics of Adolescents With Bipolar Disorder and Children of Parents With Bipolar Disorder

4. september 2012 oppdatert av: Seher Akbas, Turkish Psychiatry Association

Genetic transition is important in the etiology of bipolar disorder (BD). So, evaluation of children of BD parents and diagnosed with and BD children whether or not brain has affected zones. These groups were compared to healthy controls and whether or not the mental health of children is influenced will be evaluated by the clinical investigation.

Studieoversikt

Status

Ukjent

Forhold

Bipolar lidelse

Detaljert beskrivelse

MRI studies in children at risk of BD, our understanding of the neurobiology of BD and abnormalities in the studied regions, regions that predispose to the development of our understanding of PBB will shed light on the etiology of the disorder. In this study, the cranial MRI findings and clinical features in adolescents with bipolar disorder and the same age and sex matched children who have parents with BD and healthy controls were investigated. Since there is few studies that evaluate these three groups, there is a need to increase our knowledge on this issue.

Studietype

Observasjonsmessig

Registrering (Forventet)

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiesteder

Tyrkia
- - Samsun, Tyrkia, 55139
    - Rekruttering
    - Ondokuz Mayis University Medical Faculty Department of Child and Adolescent Psychiatry
    - Ta kontakt med:
      
      Seher Akbas
      
      Telefonnummer: 3128 00903623121919
      
      E-post: akbasseher@hotmail.com
    - Hovedetterforsker:
      
      Seher Akbas

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

12 år til 18 år (Barn, Voksen)

Tar imot friske frivillige

Kjønn som er kvalifisert for studier

Alle

Prøvetakingsmetode

Ikke-sannsynlighetsprøve

Studiepopulasjon

In this study, the cranial MRI findings and clinical features in adolescents with bipolar disorder and the same age and sex matched children who have parents with BD and healthy controls were investigated.

Beskrivelse

Inclusion Criteria:

Children with BD between the ages of 12-18
Parents with BD who have children between the ages of 12-18
Healthy children whose parents do not have BD
Patients who does not have mental or organic disability to answer the questions
Graduated from primary school

Exclusion Criteria:

Patients who have mental or organic disability to answer the questions
Patients who have a history of any chronic disease which is likely to affect the central nervous system
Patients who have a contraindication for any first application for Magnetic Resonance Imaging (MRI)

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

Antall grupper / kohorter

Kohorter og intervensjoner

Gruppe / Kohort
Patient group Children with BD, (20 children) 12-18 year-old who agreed to participate in the study will be established.
Risk group Twenty healthy children of 12-18 years old who have mothers and/or fathers who previously assessed by an adult psychiatrist and diagnosed as BD according to DSM-IV diagnostic criteria, and who agreed to participate in the study. The age and gender of the groups will be matched.
Healthy control group Twenty participants between the ages of 12-18 who agree to participate in the study and whose family members do not have BD. The age and the gender of the groups will be matched.

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

Turkish Psychiatry Association

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart

1. juli 2011

Primær fullføring (Forventet)

1. juni 2013

Studiet fullført (Forventet)