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T-DM1 og Tucatinib sammenlignet med T-DM1 alene for å forhindre tilbakefall hos personer med høyrisiko HER2-positiv brystkreft, CompassHER2 RD-prøven

11. juni 2026 oppdatert av: Alliance for Clinical Trials in Oncology

CompassHER2-studiene (omfattende bruk av patologisk responsvurdering for å optimalisere terapi ved HER2-positiv brystkreft) CompassHER2 Residual Disease (RD), en dobbeltblindet, fase III randomisert studie av T-DM1 sammenlignet med T-DM1 og Tucatinib

Denne fase III-studien studerer hvor godt trastuzumab emtansin (T-DM1) og tucatinib virker for å forhindre at brystkreft kommer tilbake (tilbakefallende) hos pasienter med høy risiko, HER2 positiv brystkreft. T-DM1 er et monoklonalt antistoff, kalt trastuzumab, knyttet til et kjemoterapilegemiddel, kalt DM1. Trastuzumab er en form for målrettet terapi fordi det fester seg til spesifikke molekyler (reseptorer) på overflaten av kreftceller, kjent som HER2-reseptorer, og leverer DM1 for å drepe dem. Tucatinib kan stoppe veksten av tumorceller ved å blokkere noen av enzymene som trengs for cellevekst. Å gi T-DM1 og tucatinib kan fungere bedre for å forhindre at brystkreft får tilbakefall hos pasienter med HER2 positiv brystkreft sammenlignet med T-DM1 alene.

Studieoversikt

Status

Aktiv, ikke rekrutterende

Forhold

Intervensjon / Behandling

Detaljert beskrivelse

HOVEDMÅL:

I. For å bestemme om den invasive sykdomsfrie overlevelsen (iDFS) med T-DM1 og tucatinib er overlegen iDFS i kontrollarmen (T-DM1 + placebo) når den administreres til høyrisikopasienter med HER2-positiv brystkreft og rester av brystkreft. sykdom etter neoadjuvant HER2-rettet behandling.

SEKUNDÆRE MÅL:

I. For å evaluere om behandling med tucatinib pluss T-DM1 sammenlignet med behandling med T-DM1 alene (T-DM1 pluss placebo) forbedrer følgende:

Ia. Brystkreftfri overlevelse (BCFS). Ib. Fjern residivfri overlevelse (DRFS). Ic. Hjernemetastasefri overlevelse (BMFS). ID. Total overlevelse (OS). II. For å evaluere om behandling med tucatinib pluss T-DM1 sammenlignet med behandling med T-DM1 alene (T-DM1 pluss placebo) reduserer forekomsten av hjernemetastaser.

OVERSIGT: Pasienter randomiseres til 1 av 2 armer.

ARM I: Pasienter får T-DM1 intravenøst (IV) over 30-90 minutter på dag 1 og placebo oralt (PO) to ganger daglig (BID) på dag 1-21. Behandlingen gjentas hver 21. dag i opptil 14 sykluser i fravær av sykdomsprogresjon eller uakseptabel toksisitet.

ARM II: Pasienter får T-DM1 IV over 30-90 minutter på dag 1 og tucatinib PO BID på dag 1-21. Behandlingen gjentas hver 21. dag i opptil 14 sykluser i fravær av sykdomsprogresjon eller uakseptabel toksisitet.

Etter avsluttet studiebehandling følges pasientene opp etter 30 dager, deretter hver 6. måned i 10 år.

Studietype

Intervensjonell

Registrering (Faktiske)

1056

Fase

Fase 3

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiesteder

Canada
- British Columbia
  - Vancouver, British Columbia, Canada, V5Z 4E6
    - BCCA-Vancouver Cancer Centre
- New Brunswick
  - Saint John, New Brunswick, Canada, E2L 4L2
    - Atlantic Health Sciences Corporation-Saint John Regional Hospital
- Ontario
  - London, Ontario, Canada, N6A 4L6
    - London Regional Cancer Program
  - Oshawa, Ontario, Canada, L1G 2B9
    - Lakeridge Health Oshawa
  - Toronto, Ontario, Canada, M4N 3M5
    - Odette Cancer Centre- Sunnybrook Health Sciences Centre
  - Toronto, Ontario, Canada, M5B 1W8
    - Saint Michael's Hospital
- Quebec
  - Québec, Quebec, Canada, G1S 4L8
    - CHU de Quebec-Hopital du Saint-Sacrement (HSS)
- Saskatchewan
  - Regina, Saskatchewan, Canada, S4T 7T1
    - Allan Blair Cancer Centre
  - Saskatoon, Saskatchewan, Canada, S7N 4H4
    - Saskatoon Cancer Centre
Forente stater
- Alabama
  - Birmingham, Alabama, Forente stater, 35233
    - University of Alabama at Birmingham Cancer Center
  - Fairhope, Alabama, Forente stater, 36532
    - Thomas Hospital
  - Mobile, Alabama, Forente stater, 36607
    - Mobile Infirmary Medical Center
- Alaska
  - Anchorage, Alaska, Forente stater, 98508
    - Anchorage Associates in Radiation Medicine
  - Anchorage, Alaska, Forente stater, 99508
    - Alaska Breast Care and Surgery LLC
  - Anchorage, Alaska, Forente stater, 99508
    - Alaska Oncology and Hematology LLC
  - Anchorage, Alaska, Forente stater, 99508
    - Alaska Women's Cancer Care
  - Anchorage, Alaska, Forente stater, 99508
    - Anchorage Oncology Centre
  - Anchorage, Alaska, Forente stater, 99508
    - Katmai Oncology Group
  - Anchorage, Alaska, Forente stater, 99508
    - Providence Alaska Medical Center
  - Anchorage, Alaska, Forente stater, 99504
    - Anchorage Radiation Therapy Center
  - Fairbanks, Alaska, Forente stater, 99701
    - Fairbanks Memorial Hospital
- Arizona
  - Gilbert, Arizona, Forente stater, 85234
    - Banner MD Anderson Cancer Center
  - Kingman, Arizona, Forente stater, 86401
    - Kingman Regional Medical Center
  - Phoenix, Arizona, Forente stater, 85004
    - Cancer Center at Saint Joseph's
  - Phoenix, Arizona, Forente stater, 85006
    - Banner-University Medical Center Phoenix
- Arkansas
  - Fort Smith, Arkansas, Forente stater, 72903
    - Mercy Hospital Fort Smith
  - Hot Springs, Arkansas, Forente stater, 71913
    - CHI Saint Vincent Cancer Center Hot Springs
  - Jonesboro, Arkansas, Forente stater, 72401
    - NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
  - Little Rock, Arkansas, Forente stater, 72205
    - University of Arkansas for Medical Sciences
- California
  - Arroyo Grande, California, Forente stater, 93420
    - PCR Oncology
  - Arroyo Grande, California, Forente stater, 93420
    - Mission Hope Medical Oncology - Arroyo Grande
  - Auburn, California, Forente stater, 95602
    - Sutter Auburn Faith Hospital
  - Auburn, California, Forente stater, 95603
    - Sutter Cancer Centers Radiation Oncology Services-Auburn
  - Berkeley, California, Forente stater, 94704
    - Alta Bates Summit Medical Center-Herrick Campus
  - Berkeley, California, Forente stater, 94702
    - UCSF Cancer Center - Berkeley
  - Beverly Hills, California, Forente stater, 90211
    - Tower Cancer Research Foundation
  - Burbank, California, Forente stater, 91505
    - Providence Saint Joseph Medical Center/Disney Family Cancer Center
  - Cameron Park, California, Forente stater, 95682
    - Sutter Cancer Centers Radiation Oncology Services-Cameron Park
  - Carmichael, California, Forente stater, 95608
    - Mercy San Juan Medical Center
  - Carmichael, California, Forente stater, 95608
    - Mercy Cancer Center - Carmichael
  - Castro Valley, California, Forente stater, 94546
    - Eden Hospital Medical Center
  - Clovis, California, Forente stater, 93611
    - Community Cancer Institute
  - Concord, California, Forente stater, 94520
    - John Muir Medical Center-Concord
  - Costa Mesa, California, Forente stater, 92627
    - UC Irvine Health Cancer Center-Newport
  - Davis, California, Forente stater, 95616
    - Sutter Davis Hospital
  - Duarte, California, Forente stater, 91010
    - City of Hope Comprehensive Cancer Center
  - Dublin, California, Forente stater, 94568
    - Kaiser Permanente Dublin
  - Dublin, California, Forente stater, 94568
    - Epic Care-Dublin
  - Elk Grove, California, Forente stater, 95758
    - Mercy Cancer Center - Elk Grove
  - Emeryville, California, Forente stater, 94608
    - Bay Area Breast Surgeons Inc
  - Emeryville, California, Forente stater, 94608
    - Epic Care Partners in Cancer Care
  - Fremont, California, Forente stater, 94538
    - Kaiser Permanente-Fremont
  - Fremont, California, Forente stater, 94538
    - Washington Hospital
  - Fremont, California, Forente stater, 94538
    - Palo Alto Medical Foundation-Fremont
  - Fresno, California, Forente stater, 93720
    - Kaiser Permanente-Fresno
  - Fullerton, California, Forente stater, 92835
    - Saint Jude Medical Center
  - Irvine, California, Forente stater, 92618
    - City of Hope at Irvine Lennar
  - Irvine, California, Forente stater, 92612
    - UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
  - Los Angeles, California, Forente stater, 90033
    - USC / Norris Comprehensive Cancer Center
  - Los Angeles, California, Forente stater, 90048
    - Cedars Sinai Medical Center
  - Los Angeles, California, Forente stater, 90020
    - Keck Medicine of USC Koreatown
  - Los Angeles, California, Forente stater, 90033
    - Los Angeles General Medical Center
  - Martinez, California, Forente stater, 94553-3156
    - Contra Costa Regional Medical Center
  - Modesto, California, Forente stater, 95355
    - Memorial Medical Center
  - Modesto, California, Forente stater, 95356
    - Kaiser Permanente-Modesto
  - Mountain View, California, Forente stater, 94040
    - Palo Alto Medical Foundation-Camino Division
  - Mountain View, California, Forente stater, 94040
    - Palo Alto Medical Foundation-Gynecologic Oncology
  - Newport Beach, California, Forente stater, 92663
    - USC Norris Oncology/Hematology-Newport Beach
  - Newport Beach, California, Forente stater, 92660
    - City of Hope Newport Beach
  - Oakland, California, Forente stater, 94611
    - Kaiser Permanente-Oakland
  - Oakland, California, Forente stater, 94609
    - Alta Bates Summit Medical Center - Summit Campus
  - Oakland, California, Forente stater, 94609
    - Bay Area Tumor Institute
  - Orange, California, Forente stater, 92868
    - UC Irvine Health/Chao Family Comprehensive Cancer Center
  - Orange, California, Forente stater, 92868
    - Saint Joseph Hospital - Orange
  - Palm Springs, California, Forente stater, 92262
    - Desert Regional Medical Center
  - Palo Alto, California, Forente stater, 94304
    - Stanford Cancer Institute Palo Alto
  - Palo Alto, California, Forente stater, 94301
    - Palo Alto Medical Foundation Health Care
  - Pasadena, California, Forente stater, 91105
    - Huntington Memorial Hospital
  - Pasadena, California, Forente stater, 91105
    - Keck Medical Center of USC Pasadena
  - Rancho Mirage, California, Forente stater, 92270
    - Eisenhower Medical Center
  - Rocklin, California, Forente stater, 95765
    - Mercy Cancer Center - Rocklin
  - Roseville, California, Forente stater, 95661
    - Kaiser Permanente-Roseville
  - Roseville, California, Forente stater, 95661
    - Sutter Cancer Centers Radiation Oncology Services-Roseville
  - Roseville, California, Forente stater, 95661
    - Sutter Roseville Medical Center
  - Sacramento, California, Forente stater, 95816
    - Sutter Medical Center Sacramento
  - Sacramento, California, Forente stater, 95817
    - University of California Davis Comprehensive Cancer Center
  - Sacramento, California, Forente stater, 95814
    - Kaiser Permanente Downtown Commons
  - Sacramento, California, Forente stater, 95823
    - Kaiser Permanente-South Sacramento
  - Sacramento, California, Forente stater, 95816
    - Mercy Cancer Center - Sacramento
  - Salinas, California, Forente stater, 93901
    - Salinas Valley Memorial
  - San Francisco, California, Forente stater, 94115
    - Kaiser Permanente-San Francisco
  - San Francisco, California, Forente stater, 94158
    - UCSF Medical Center-Mission Bay
  - San Francisco, California, Forente stater, 94115
    - California Pacific Medical Center-Pacific Campus
  - San Francisco, California, Forente stater, 94110
    - Zuckerberg San Francisco General Hospital
  - San Jose, California, Forente stater, 95119
    - Kaiser Permanente-Santa Teresa-San Jose
  - San Jose, California, Forente stater, 95124
    - Stanford Cancer Center South Bay
  - San Leandro, California, Forente stater, 94577
    - Kaiser Permanente San Leandro
  - San Luis Obispo, California, Forente stater, 93401
    - Pacific Central Coast Health Center-San Luis Obispo
  - San Mateo, California, Forente stater, 94402
    - UCSF Cancer Center - San Mateo
  - San Rafael, California, Forente stater, 94903
    - Kaiser San Rafael-Gallinas
  - Santa Clara, California, Forente stater, 95051
    - Kaiser Permanente Medical Center - Santa Clara
  - Santa Cruz, California, Forente stater, 95065
    - Palo Alto Medical Foundation-Santa Cruz
  - Santa Maria, California, Forente stater, 93444
    - Mission Hope Medical Oncology - Santa Maria
  - Santa Monica, California, Forente stater, 90404
    - Saint John's Cancer Institute
  - Santa Rosa, California, Forente stater, 95403
    - Kaiser Permanente-Santa Rosa
  - Santa Rosa, California, Forente stater, 95403
    - Sutter Pacific Medical Foundation
  - Santa Rosa, California, Forente stater, 95403
    - Providence Medical Foundation - Santa Rosa
  - Santa Rosa, California, Forente stater, 95405
    - Providence Santa Rosa Memorial Hospital
  - South Pasadena, California, Forente stater, 91030
    - City of Hope South Pasadena
  - South San Francisco, California, Forente stater, 94080
    - Kaiser Permanente-South San Francisco
  - St. Helena, California, Forente stater, 94574
    - Saint Helena Hospital
  - Sunnyvale, California, Forente stater, 94086
    - Palo Alto Medical Foundation-Sunnyvale
  - Torrance, California, Forente stater, 90505
    - Torrance Memorial Physician Network - Cancer Care
  - Torrance, California, Forente stater, 90503
    - City of Hope South Bay
  - Upland, California, Forente stater, 91786
    - City of Hope Upland
  - Vacaville, California, Forente stater, 95687
    - Sutter Cancer Centers Radiation Oncology Services-Vacaville
  - Vallejo, California, Forente stater, 94589
    - Kaiser Permanente-Vallejo
  - Vallejo, California, Forente stater, 94589
    - Sutter Solano Medical Center/Cancer Center
  - Walnut Creek, California, Forente stater, 94596
    - Kaiser Permanente-Walnut Creek
  - Walnut Creek, California, Forente stater, 94598
    - John Muir Medical Center-Walnut Creek
  - Walnut Creek, California, Forente stater, 94597
    - Epic Care Cyberknife Center
  - Woodland, California, Forente stater, 95695
    - Woodland Memorial Hospital
- Colorado
  - Aurora, Colorado, Forente stater, 80012
    - Rocky Mountain Cancer Centers-Aurora
  - Aurora, Colorado, Forente stater, 80012
    - The Medical Center of Aurora
  - Aurora, Colorado, Forente stater, 80045
    - UCHealth University of Colorado Hospital
  - Boulder, Colorado, Forente stater, 80303
    - Boulder Community Foothills Hospital
  - Boulder, Colorado, Forente stater, 80304
    - Rocky Mountain Cancer Centers-Boulder
  - Centennial, Colorado, Forente stater, 80112
    - Rocky Mountain Cancer Centers - Centennial
  - Colorado Springs, Colorado, Forente stater, 80907
    - Penrose-Saint Francis Healthcare
  - Colorado Springs, Colorado, Forente stater, 80909
    - UCHealth Memorial Hospital Central
  - Colorado Springs, Colorado, Forente stater, 80907
    - Rocky Mountain Cancer Centers-Penrose
  - Colorado Springs, Colorado, Forente stater, 80920
    - Memorial Hospital North
  - Denver, Colorado, Forente stater, 80210
    - Porter Adventist Hospital
  - Denver, Colorado, Forente stater, 80218
    - Presbyterian - Saint Lukes Medical Center - Health One
  - Denver, Colorado, Forente stater, 80218
    - SCL Health Saint Joseph Hospital
  - Denver, Colorado, Forente stater, 80220
    - Rose Medical Center
  - Denver, Colorado, Forente stater, 80218
    - Rocky Mountain Cancer Centers-Midtown
  - Denver, Colorado, Forente stater, 80220
    - Rocky Mountain Cancer Centers-Rose
  - Denver, Colorado, Forente stater, 80218
    - Colorado Blood Cancer Institute
  - Denver, Colorado, Forente stater, 80204
    - Cancer Center of Colorado at Sloan's Lake
  - Denver, Colorado, Forente stater, 80209
    - The Women's Imaging Center
  - Denver, Colorado, Forente stater, 80206
    - National Jewish Health-Main Campus
  - Denver, Colorado, Forente stater, 80220
    - Western Surgical Care
  - Denver, Colorado, Forente stater, 80206
    - UCHealth - Cherry Creek
  - Durango, Colorado, Forente stater, 81301
    - Mercy Medical Center
  - Durango, Colorado, Forente stater, 81301
    - Southwest Oncology PC
  - Edwards, Colorado, Forente stater, 81632
    - Shaw Cancer Center
  - Englewood, Colorado, Forente stater, 80113
    - Mountain Blue Cancer Care Center - Swedish
  - Englewood, Colorado, Forente stater, 80113
    - Swedish Medical Center
  - Englewood, Colorado, Forente stater, 80113
    - Rocky Mountain Cancer Centers - Swedish
  - Englewood, Colorado, Forente stater, 80113
    - The Melanoma and Skin Cancer Institute
  - Fort Collins, Colorado, Forente stater, 80524
    - Poudre Valley Hospital
  - Fort Collins, Colorado, Forente stater, 80528
    - Cancer Care and Hematology-Fort Collins
  - Golden, Colorado, Forente stater, 80401
    - National Jewish Health-Western Hematology Oncology
  - Golden, Colorado, Forente stater, 80401
    - SCL Health Cancer Centers of Colorado - Lutheran Medical Center
  - Grand Junction, Colorado, Forente stater, 81501
    - Saint Mary's Hospital and Regional Medical Center
  - Grand Junction, Colorado, Forente stater, 81505
    - Grand Valley Oncology
  - Greeley, Colorado, Forente stater, 80631
    - UCHealth Greeley Hospital
  - Greeley, Colorado, Forente stater, 80631
    - Banner North Colorado Medical Center
  - Highlands Ranch, Colorado, Forente stater, 80129
    - UCHealth Highlands Ranch Hospital
  - Lafayette, Colorado, Forente stater, 80026
    - Good Samaritan Medical Center
  - Lakewood, Colorado, Forente stater, 80228
    - Saint Anthony Hospital
  - Lakewood, Colorado, Forente stater, 80228
    - Rocky Mountain Cancer Centers-Lakewood
  - Littleton, Colorado, Forente stater, 80120
    - Rocky Mountain Cancer Centers-Littleton
  - Littleton, Colorado, Forente stater, 80122
    - Littleton Adventist Hospital
  - Lone Tree, Colorado, Forente stater, 80124
    - Sky Ridge Medical Center
  - Lone Tree, Colorado, Forente stater, 80124
    - Rocky Mountain Cancer Centers-Sky Ridge
  - Lone Tree, Colorado, Forente stater, 80124
    - UCHealth Lone Tree Health Center
  - Longmont, Colorado, Forente stater, 80501
    - Longmont United Hospital
  - Longmont, Colorado, Forente stater, 80501
    - Rocky Mountain Cancer Centers-Longmont
  - Loveland, Colorado, Forente stater, 80538
    - Medical Center of the Rockies
  - Loveland, Colorado, Forente stater, 80539
    - Banner McKee Medical Center
  - Parker, Colorado, Forente stater, 80138
    - Parker Adventist Hospital
  - Pueblo, Colorado, Forente stater, 81004
    - Saint Mary Corwin Medical Center
  - Thornton, Colorado, Forente stater, 80260
    - Rocky Mountain Cancer Centers-Thornton
  - Thornton, Colorado, Forente stater, 80260
    - National Jewish Health-Northern Hematology Oncology
  - Wheat Ridge, Colorado, Forente stater, 80033
    - SCL Health Lutheran Medical Center
- Connecticut
  - Bridgeport, Connecticut, Forente stater, 06606
    - Hartford HealthCare - Saint Vincent's Medical Center
  - Danbury, Connecticut, Forente stater, 06810
    - Danbury Hospital
  - Fairfield, Connecticut, Forente stater, 06824
    - Smilow Cancer Hospital Care Center-Fairfield
  - Glastonbury, Connecticut, Forente stater, 06033
    - Smilow Cancer Hospital Care Center at Glastonbury
  - Hartford, Connecticut, Forente stater, 06105
    - Smilow Cancer Hospital Care Center at Saint Francis
  - Hartford, Connecticut, Forente stater, 06102
    - Hartford Hospital
  - Meriden, Connecticut, Forente stater, 06451
    - Midstate Medical Center
  - New Britain, Connecticut, Forente stater, 06050
    - The Hospital of Central Connecticut
  - New Haven, Connecticut, Forente stater, 06520
    - Yale University
  - North Haven, Connecticut, Forente stater, 06473
    - Yale-New Haven Hospital North Haven Medical Center
  - Norwalk, Connecticut, Forente stater, 06856
    - Norwalk Hospital
  - Stamford, Connecticut, Forente stater, 06904
    - Stamford Hospital/Bennett Cancer Center
  - Torrington, Connecticut, Forente stater, 06790
    - Smilow Cancer Hospital-Torrington Care Center
  - Trumbull, Connecticut, Forente stater, 06611
    - Smilow Cancer Hospital Care Center-Trumbull
  - Waterbury, Connecticut, Forente stater, 06708
    - Smilow Cancer Hospital-Waterbury Care Center
  - Waterford, Connecticut, Forente stater, 06385
    - Smilow Cancer Hospital Care Center - Waterford
- Delaware
  - Frankford, Delaware, Forente stater, 19945
    - Beebe South Coastal Health Campus
  - Lewes, Delaware, Forente stater, 19958
    - Beebe Medical Center
  - Newark, Delaware, Forente stater, 19713
    - Helen F Graham Cancer Center
  - Newark, Delaware, Forente stater, 19713
    - Delaware Clinical and Laboratory Physicians PA
  - Newark, Delaware, Forente stater, 19713
    - Medical Oncology Hematology Consultants PA
  - Newark, Delaware, Forente stater, 19718
    - Christiana Care Health System-Christiana Hospital
  - Rehoboth Beach, Delaware, Forente stater, 19971
    - Beebe Health Campus
  - Seaford, Delaware, Forente stater, 19973
    - TidalHealth Nanticoke / Allen Cancer Center
  - Wilmington, Delaware, Forente stater, 19801
    - Christiana Care Health System-Wilmington Hospital
- District of Columbia
  - Washington D.C., District of Columbia, Forente stater, 20010
    - MedStar Washington Hospital Center
  - Washington D.C., District of Columbia, Forente stater, 20002
    - Kaiser Permanente-Capitol Hill Medical Center
  - Washington D.C., District of Columbia, Forente stater, 20007
    - MedStar Georgetown University Hospital
  - Washington D.C., District of Columbia, Forente stater, 20016
    - Sibley Memorial Hospital
- Florida
  - Altamonte Springs, Florida, Forente stater, 32701
    - AdventHealth Altamonte
  - Aventura, Florida, Forente stater, 33180
    - Mount Sinai Comprehensive Cancer Center at Aventura
  - Aventura, Florida, Forente stater, 33180
    - UM Sylvester Comprehensive Cancer Center at Aventura
  - Boca Raton, Florida, Forente stater, 33486
    - Boca Raton Regional Hospital
  - Celebration, Florida, Forente stater, 34747
    - AdventHealth Celebration
  - Clearwater, Florida, Forente stater, 33756
    - Morton Plant Hospital
  - Coral Gables, Florida, Forente stater, 33146
    - UM Sylvester Comprehensive Cancer Center at Coral Gables
  - Deerfield Beach, Florida, Forente stater, 33442
    - UM Sylvester Comprehensive Cancer Center at Deerfield Beach
  - Fort Lauderdale, Florida, Forente stater, 33308
    - Holy Cross Hospital
  - Hollywood, Florida, Forente stater, 33021
    - Memorial Regional Hospital/Joe DiMaggio Children's Hospital
  - Jacksonville, Florida, Forente stater, 32224-9980
    - Mayo Clinic in Florida
  - Kissimmee, Florida, Forente stater, 34744
    - AdventHealth Kissimmee
  - Miami, Florida, Forente stater, 33136
    - University of Miami Miller School of Medicine-Sylvester Cancer Center
  - Miami, Florida, Forente stater, 33176
    - UM Sylvester Comprehensive Cancer Center at Kendall
  - Miami Beach, Florida, Forente stater, 33140
    - Mount Sinai Medical Center
  - Orlando, Florida, Forente stater, 32806
    - Orlando Health Cancer Institute
  - Orlando, Florida, Forente stater, 32803
    - AdventHealth Orlando
  - Orlando, Florida, Forente stater, 32803
    - AdventHealth Medical Group Urology at Orlando
  - Orlando, Florida, Forente stater, 32822
    - AdventHealth East Orlando
  - Pembroke Pines, Florida, Forente stater, 33028
    - Memorial Hospital West
  - Pensacola, Florida, Forente stater, 32504
    - Sacred Heart Hospital
  - Plantation, Florida, Forente stater, 33324
    - UM Sylvester Comprehensive Cancer Center at Plantation
  - Safety Harbor, Florida, Forente stater, 34695
    - Mease Countryside Hospital
  - St. Petersburg, Florida, Forente stater, 33705
    - Saint Anthony's Hospital Cancer Care Center
  - Tampa, Florida, Forente stater, 33606
    - Tampa General Hospital
  - Tampa, Florida, Forente stater, 33607
    - Saint Joseph's Hospital/Children's Hospital-Tampa
  - Winter Haven, Florida, Forente stater, 33881
    - Winter Haven Hospital
  - Winter Park, Florida, Forente stater, 32792
    - AdventHealth Winter Park
- Georgia
  - Albany, Georgia, Forente stater, 31701
    - Phoebe Putney Memorial Hospital
  - Athens, Georgia, Forente stater, 30607
    - University Cancer and Blood Center LLC
  - Atlanta, Georgia, Forente stater, 30308
    - Emory University Hospital Midtown
  - Atlanta, Georgia, Forente stater, 30322
    - Emory University Hospital/Winship Cancer Institute
  - Atlanta, Georgia, Forente stater, 30342
    - Emory Saint Joseph's Hospital
  - Atlanta, Georgia, Forente stater, 30303
    - Grady Health System
  - Atlanta, Georgia, Forente stater, 30342
    - Northside Hospital
  - Augusta, Georgia, Forente stater, 30901
    - Augusta Oncology Associates PC-D'Antignac
  - Augusta, Georgia, Forente stater, 30909
    - Augusta Oncology Associates PC-Wheeler
  - Decatur, Georgia, Forente stater, 30033
    - Atlanta VA Medical Center
  - Duluth, Georgia, Forente stater, 30096
    - Northside Hospital - Duluth
  - Lawrenceville, Georgia, Forente stater, 30046
    - Northside Hospital - Gwinnett
  - Newnan, Georgia, Forente stater, 30265
    - CTCA at Southeastern Regional Medical Center
  - Savannah, Georgia, Forente stater, 31405
    - Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
  - Savannah, Georgia, Forente stater, 31404
    - Memorial Health University Medical Center
  - Savannah, Georgia, Forente stater, 31404
    - Summit Cancer Care-Memorial
  - Snellville, Georgia, Forente stater, 30078
    - Suburban Hematology Oncology Associates - Snellville
- Hawaii
  - Hilo, Hawaii, Forente stater, 96720
    - Island Urology-Hilo
  - Honolulu, Hawaii, Forente stater, 96813
    - Queen's Medical Center
  - Honolulu, Hawaii, Forente stater, 96817
    - The Cancer Center of Hawaii-Liliha
  - Honolulu, Hawaii, Forente stater, 96813
    - Hawaii Cancer Care Inc - Waterfront Plaza
  - Honolulu, Hawaii, Forente stater, 96813
    - Queen's Cancer Cenrer - POB I
  - Honolulu, Hawaii, Forente stater, 96813
    - Straub Clinic and Hospital
  - Honolulu, Hawaii, Forente stater, 96813
    - University of Hawaii Cancer Center
  - Honolulu, Hawaii, Forente stater, 96817
    - Hawaii Cancer Care Inc-Liliha
  - Honolulu, Hawaii, Forente stater, 96817
    - Kuakini Medical Center
  - Honolulu, Hawaii, Forente stater, 96817
    - Queen's Cancer Center - Kuakini
  - Honolulu, Hawaii, Forente stater, 96826
    - Kapiolani Medical Center for Women and Children
  - Honolulu, Hawaii, Forente stater, 96813
    - Island Urology
  - Honolulu, Hawaii, Forente stater, 96819
    - Kaiser Permanente Moanalua Medical Center
  - Lihue, Hawaii, Forente stater, 96766
    - Wilcox Memorial Hospital and Kauai Medical Clinic
  - ‘Aiea, Hawaii, Forente stater, 96701
    - Hawaii Cancer Care - Westridge
  - ‘Aiea, Hawaii, Forente stater, 96701
    - Pali Momi Medical Center
  - ‘Aiea, Hawaii, Forente stater, 96701
    - Queen's Cancer Center - Pearlridge
  - ‘Aiea, Hawaii, Forente stater, 96701
    - The Cancer Center of Hawaii-Pali Momi
- Idaho
  - Boise, Idaho, Forente stater, 83706
    - Saint Alphonsus Cancer Care Center-Boise
  - Boise, Idaho, Forente stater, 83712
    - Saint Luke's Cancer Institute - Boise
  - Caldwell, Idaho, Forente stater, 83605
    - Saint Alphonsus Cancer Care Center-Caldwell
  - Coeur d'Alene, Idaho, Forente stater, 83814
    - Kootenai Health - Coeur d'Alene
  - Emmett, Idaho, Forente stater, 83617
    - Walter Knox Memorial Hospital
  - Fruitland, Idaho, Forente stater, 83619
    - Saint Luke's Cancer Institute - Fruitland
  - Meridian, Idaho, Forente stater, 83642
    - Idaho Urologic Institute-Meridian
  - Meridian, Idaho, Forente stater, 83642
    - Saint Luke's Cancer Institute - Meridian
  - Nampa, Idaho, Forente stater, 83686
    - Saint Luke's Cancer Institute - Nampa
  - Nampa, Idaho, Forente stater, 83687
    - Saint Alphonsus Cancer Care Center-Nampa
  - Post Falls, Idaho, Forente stater, 83854
    - Kootenai Clinic Cancer Services - Post Falls
  - Sandpoint, Idaho, Forente stater, 83864
    - Kootenai Clinic Cancer Services - Sandpoint
  - Twin Falls, Idaho, Forente stater, 83301
    - Saint Luke's Cancer Institute - Twin Falls
- Illinois
  - Alton, Illinois, Forente stater, 62002
    - Saint Anthony's Health
  - Arlington Heights, Illinois, Forente stater, 60005
    - Northwest Community Hospital
  - Aurora, Illinois, Forente stater, 60504
    - Rush - Copley Medical Center
  - Barrington, Illinois, Forente stater, 60010
    - Advocate Good Shepherd Hospital
  - Bloomington, Illinois, Forente stater, 61704
    - Illinois CancerCare-Bloomington
  - Canton, Illinois, Forente stater, 61520
    - Illinois CancerCare-Canton
  - Carbondale, Illinois, Forente stater, 62902
    - Memorial Hospital of Carbondale
  - Carterville, Illinois, Forente stater, 62918
    - SIH Cancer Institute
  - Carthage, Illinois, Forente stater, 62321
    - Illinois CancerCare-Carthage
  - Centralia, Illinois, Forente stater, 62801
    - Centralia Oncology Clinic
  - Chicago, Illinois, Forente stater, 60611
    - Northwestern University
  - Chicago, Illinois, Forente stater, 60612
    - Rush University Medical Center
  - Chicago, Illinois, Forente stater, 60637
    - University of Chicago Comprehensive Cancer Center
  - Chicago, Illinois, Forente stater, 60612
    - University of Illinois
  - Chicago, Illinois, Forente stater, 60612
    - John H Stroger Jr Hospital of Cook County
  - Chicago, Illinois, Forente stater, 60608
    - Mount Sinai Hospital Medical Center
  - Chicago, Illinois, Forente stater, 60625
    - Swedish Covenant Hospital
  - Chicago, Illinois, Forente stater, 60657
    - Advocate Illinois Masonic Medical Center
  - Crystal Lake, Illinois, Forente stater, 60014
    - AMG Crystal Lake - Oncology
  - Danville, Illinois, Forente stater, 61832
    - Carle at The Riverfront
  - DeKalb, Illinois, Forente stater, 60115
    - Northwestern Medicine Cancer Center Kishwaukee
  - Decatur, Illinois, Forente stater, 62526
    - Decatur Memorial Hospital
  - Decatur, Illinois, Forente stater, 62526
    - Cancer Care Specialists of Illinois - Decatur
  - Dixon, Illinois, Forente stater, 61021
    - Illinois CancerCare-Dixon
  - Downers Grove, Illinois, Forente stater, 60515
    - Advocate Good Samaritan Hospital
  - Effingham, Illinois, Forente stater, 62401
    - Crossroads Cancer Center
  - Effingham, Illinois, Forente stater, 62401
    - Carle Physician Group-Effingham
  - Elgin, Illinois, Forente stater, 60123
    - Advocate Sherman Hospital
  - Eureka, Illinois, Forente stater, 61530
    - Illinois CancerCare-Eureka
  - Evanston, Illinois, Forente stater, 60201
    - NorthShore University HealthSystem-Evanston Hospital
  - Galesburg, Illinois, Forente stater, 61401
    - Western Illinois Cancer Treatment Center
  - Galesburg, Illinois, Forente stater, 61401
    - Illinois CancerCare-Galesburg
  - Geneva, Illinois, Forente stater, 60134
    - Northwestern Medicine Cancer Center Delnor
  - Glenview, Illinois, Forente stater, 60026
    - NorthShore University HealthSystem-Glenbrook Hospital
  - Glenview, Illinois, Forente stater, 60026
    - Northwestern Medicine Glenview Outpatient Center
  - Grayslake, Illinois, Forente stater, 60030
    - Northwestern Medicine Grayslake Outpatient Center
  - Harvey, Illinois, Forente stater, 60426
    - Ingalls Memorial Hospital
  - Hazel Crest, Illinois, Forente stater, 60429
    - Advocate South Suburban Hospital
  - Highland Park, Illinois, Forente stater, 60035
    - NorthShore University HealthSystem-Highland Park Hospital
  - Kewanee, Illinois, Forente stater, 61443
    - Illinois CancerCare-Kewanee Clinic
  - Lake Forest, Illinois, Forente stater, 60045
    - Northwestern Medicine Lake Forest Hospital
  - Libertyville, Illinois, Forente stater, 60048
    - Condell Memorial Hospital
  - Libertyville, Illinois, Forente stater, 60048
    - AMG Libertyville - Oncology
  - Macomb, Illinois, Forente stater, 61455
    - Illinois CancerCare-Macomb
  - Mattoon, Illinois, Forente stater, 61938
    - Carle Physician Group-Mattoon/Charleston
  - Mount Vernon, Illinois, Forente stater, 62864
    - Good Samaritan Regional Health Center
  - New Lenox, Illinois, Forente stater, 60451
    - UC Comprehensive Cancer Center at Silver Cross
  - O'Fallon, Illinois, Forente stater, 62269
    - Cancer Care Center of O'Fallon
  - Oak Lawn, Illinois, Forente stater, 60453-2699
    - Advocate Christ Medical Center
  - Orland Park, Illinois, Forente stater, 60462
    - University of Chicago Medicine-Orland Park
  - Orland Park, Illinois, Forente stater, 60462
    - Northwestern Medicine Orland Park
  - Ottawa, Illinois, Forente stater, 61350
    - Illinois CancerCare-Ottawa Clinic
  - Park Ridge, Illinois, Forente stater, 60068
    - Advocate Lutheran General Hospital
  - Pekin, Illinois, Forente stater, 61554
    - Illinois CancerCare-Pekin
  - Pekin, Illinois, Forente stater, 61554
    - OSF Saint Francis Radiation Oncology at Pekin
  - Peoria, Illinois, Forente stater, 61636
    - Methodist Medical Center of Illinois
  - Peoria, Illinois, Forente stater, 61637
    - OSF Saint Francis Medical Center
  - Peoria, Illinois, Forente stater, 61615
    - Illinois CancerCare-Peoria
  - Peoria, Illinois, Forente stater, 61615
    - OSF Saint Francis Radiation Oncology at Peoria Cancer Center
  - Peru, Illinois, Forente stater, 61354
    - Illinois CancerCare-Peru
  - Peru, Illinois, Forente stater, 61354
    - Valley Radiation Oncology
  - Princeton, Illinois, Forente stater, 61356
    - Illinois CancerCare-Princeton
  - Rockford, Illinois, Forente stater, 61108
    - OSF Saint Anthony Medical Center
  - Rockford, Illinois, Forente stater, 61114
    - UW Health Carbone Cancer Center Rockford
  - Shiloh, Illinois, Forente stater, 62269
    - Memorial Hospital East
  - Silvis, Illinois, Forente stater, 61282
    - Genesis Cancer Center - Silvis
  - Springfield, Illinois, Forente stater, 62781
    - Memorial Medical Center
  - Springfield, Illinois, Forente stater, 62702
    - Southern Illinois University School of Medicine
  - Springfield, Illinois, Forente stater, 62702
    - Springfield Clinic
  - Urbana, Illinois, Forente stater, 61801
    - Carle Cancer Center
  - Urbana, Illinois, Forente stater, 61801
    - The Carle Foundation Hospital
  - Warrenville, Illinois, Forente stater, 60555
    - Northwestern Medicine Cancer Center Warrenville
  - Washington, Illinois, Forente stater, 61571
    - Illinois CancerCare - Washington
  - Yorkville, Illinois, Forente stater, 60560
    - Rush-Copley Healthcare Center
- Indiana
  - Carmel, Indiana, Forente stater, 46032
    - IU Health North Hospital
  - Indianapolis, Indiana, Forente stater, 46237
    - Franciscan Health Indianapolis
  - Indianapolis, Indiana, Forente stater, 46202
    - Indiana University/Melvin and Bren Simon Cancer Center
  - Indianapolis, Indiana, Forente stater, 46219
    - Community Cancer Center East
  - Indianapolis, Indiana, Forente stater, 46227
    - Community Cancer Center South
  - Indianapolis, Indiana, Forente stater, 46256
    - Community Cancer Center North
  - Indianapolis, Indiana, Forente stater, 46202
    - Sidney and Lois Eskenazi Hospital
  - Kokomo, Indiana, Forente stater, 46904
    - Community Howard Regional Health
  - Lafayette, Indiana, Forente stater, 47905
    - Franciscan Saint Elizabeth Health - Lafayette East
  - Michigan City, Indiana, Forente stater, 46360
    - Woodland Cancer Care Center
  - Mooresville, Indiana, Forente stater, 46158
    - Franciscan Health Mooresville
  - Richmond, Indiana, Forente stater, 47374
    - Reid Health
  - South Bend, Indiana, Forente stater, 46601
    - Memorial Hospital of South Bend
- Iowa
  - Ames, Iowa, Forente stater, 50010
    - Mary Greeley Medical Center
  - Ames, Iowa, Forente stater, 50010
    - McFarland Clinic - Ames
  - Ankeny, Iowa, Forente stater, 50023
    - Mission Cancer and Blood - Ankeny
  - Boone, Iowa, Forente stater, 50036
    - McFarland Clinic - Boone
  - Carroll, Iowa, Forente stater, 51401
    - Saint Anthony Regional Hospital
  - Cedar Rapids, Iowa, Forente stater, 52403
    - Mercy Hospital
  - Cedar Rapids, Iowa, Forente stater, 52403
    - Oncology Associates at Mercy Medical Center
  - Cedar Rapids, Iowa, Forente stater, 52402
    - Physicians' Clinic of Iowa PC
  - Clive, Iowa, Forente stater, 50325
    - Mercy Cancer Center-West Lakes
  - Clive, Iowa, Forente stater, 50325
    - Mission Cancer and Blood - West Des Moines
  - Council Bluffs, Iowa, Forente stater, 51503
    - Alegent Health Mercy Hospital
  - Council Bluffs, Iowa, Forente stater, 51503
    - Heartland Oncology and Hematology LLP
  - Council Bluffs, Iowa, Forente stater, 51503
    - Methodist Jennie Edmundson Hospital
  - Creston, Iowa, Forente stater, 50801
    - Greater Regional Medical Center
  - Davenport, Iowa, Forente stater, 52803
    - Genesis Medical Center - East Campus
  - Davenport, Iowa, Forente stater, 52804
    - Genesis Cancer Care Institute
  - Davenport, Iowa, Forente stater, 52807
    - Iowa Cancer Specialists
  - Des Moines, Iowa, Forente stater, 50309
    - Iowa Methodist Medical Center
  - Des Moines, Iowa, Forente stater, 50314
    - Mercy Medical Center - Des Moines
  - Des Moines, Iowa, Forente stater, 50314
    - Broadlawns Medical Center
  - Des Moines, Iowa, Forente stater, 50314
    - Mission Cancer and Blood - Laurel
  - Des Moines, Iowa, Forente stater, 50316
    - Iowa Lutheran Hospital
  - Des Moines, Iowa, Forente stater, 50309
    - Mission Cancer and Blood - Des Moines
  - Fort Dodge, Iowa, Forente stater, 50501
    - Trinity Regional Medical Center
  - Fort Dodge, Iowa, Forente stater, 50501
    - McFarland Clinic - Trinity Cancer Center
  - Jefferson, Iowa, Forente stater, 50129
    - McFarland Clinic - Jefferson
  - Marshalltown, Iowa, Forente stater, 50158
    - McFarland Clinic - Marshalltown
  - Sioux City, Iowa, Forente stater, 51101
    - Siouxland Regional Cancer Center
  - West Des Moines, Iowa, Forente stater, 50266-7700
    - Methodist West Hospital
  - West Des Moines, Iowa, Forente stater, 50266
    - Mercy Medical Center-West Lakes
- Kansas
  - Chanute, Kansas, Forente stater, 66720
    - Cancer Center of Kansas - Chanute
  - Dodge City, Kansas, Forente stater, 67801
    - Cancer Center of Kansas - Dodge City
  - El Dorado, Kansas, Forente stater, 67042
    - Cancer Center of Kansas - El Dorado
  - Garden City, Kansas, Forente stater, 67846
    - Central Care Cancer Center - Garden City
  - Great Bend, Kansas, Forente stater, 67530
    - Central Care Cancer Center - Great Bend
  - Hays, Kansas, Forente stater, 67601
    - HaysMed
  - Independence, Kansas, Forente stater, 67301
    - Cancer Center of Kansas-Independence
  - Kingman, Kansas, Forente stater, 67068
    - Cancer Center of Kansas-Kingman
  - Lawrence, Kansas, Forente stater, 66044
    - Lawrence Memorial Hospital
  - Liberal, Kansas, Forente stater, 67905
    - Cancer Center of Kansas-Liberal
  - Manhattan, Kansas, Forente stater, 66502
    - Cancer Center of Kansas-Manhattan
  - McPherson, Kansas, Forente stater, 67460
    - Cancer Center of Kansas - McPherson
  - Newton, Kansas, Forente stater, 67114
    - Cancer Center of Kansas - Newton
  - Olathe, Kansas, Forente stater, 66061
    - Olathe Health Cancer Center
  - Overland Park, Kansas, Forente stater, 66210
    - University of Kansas Cancer Center-Overland Park
  - Overland Park, Kansas, Forente stater, 66209
    - Menorah Medical Center
  - Overland Park, Kansas, Forente stater, 66211
    - University of Kansas Hospital-Indian Creek Campus
  - Parsons, Kansas, Forente stater, 67357
    - Cancer Center of Kansas - Parsons
  - Pittsburg, Kansas, Forente stater, 66762
    - Ascension Via Christi - Pittsburg
  - Pittsburg, Kansas, Forente stater, 66762
    - Freeman Physician Group of Pittsburg
  - Pratt, Kansas, Forente stater, 67124
    - Cancer Center of Kansas - Pratt
  - Salina, Kansas, Forente stater, 67401
    - Salina Regional Health Center
  - Salina, Kansas, Forente stater, 67401
    - Cancer Center of Kansas - Salina
  - Topeka, Kansas, Forente stater, 66606
    - University of Kansas Health System Saint Francis Campus
  - Wellington, Kansas, Forente stater, 67152
    - Cancer Center of Kansas - Wellington
  - Westwood, Kansas, Forente stater, 66205
    - University of Kansas Hospital-Westwood Cancer Center
  - Wichita, Kansas, Forente stater, 67214
    - Ascension Via Christi Hospitals Wichita
  - Wichita, Kansas, Forente stater, 67208
    - Cancer Center of Kansas-Wichita Medical Arts Tower
  - Wichita, Kansas, Forente stater, 67214
    - Cancer Center of Kansas - Wichita
  - Winfield, Kansas, Forente stater, 67156
    - Cancer Center of Kansas - Winfield
- Kentucky
  - Ashland, Kentucky, Forente stater, 41101
    - King's Daughter's Medical Center
  - Bardstown, Kentucky, Forente stater, 40004
    - Flaget Memorial Hospital
  - Corbin, Kentucky, Forente stater, 40701
    - Baptist Health Corbin
  - Corbin, Kentucky, Forente stater, 40701
    - Commonwealth Cancer Center-Corbin
  - Lexington, Kentucky, Forente stater, 40536
    - University of Kentucky/Markey Cancer Center
  - Lexington, Kentucky, Forente stater, 40504
    - Saint Joseph Radiation Oncology Resource Center
  - Lexington, Kentucky, Forente stater, 40509
    - Saint Joseph Hospital East
  - Lexington, Kentucky, Forente stater, 40503
    - Baptist Health Lexington
  - London, Kentucky, Forente stater, 40741
    - Saint Joseph London
  - Louisville, Kentucky, Forente stater, 40202
    - Jewish Hospital
  - Louisville, Kentucky, Forente stater, 40245
    - UofL Health Medical Center Northeast
  - Louisville, Kentucky, Forente stater, 40207
    - Baptist Health Louisville
  - Louisville, Kentucky, Forente stater, 40215
    - Saints Mary and Elizabeth Hospital
  - Shepherdsville, Kentucky, Forente stater, 40165
    - Jewish Hospital Medical Center South
- Louisiana
  - Metairie, Louisiana, Forente stater, 70006
    - East Jefferson General Hospital
  - New Orleans, Louisiana, Forente stater, 70112
    - University Medical Center New Orleans
  - New Orleans, Louisiana, Forente stater, 70112
    - Louisiana State University Health Science Center
  - Shreveport, Louisiana, Forente stater, 71103
    - LSU Health Sciences Center at Shreveport
- Maine
  - Augusta, Maine, Forente stater, 04330
    - Harold Alfond Center for Cancer Care
  - Biddeford, Maine, Forente stater, 04005
    - MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford
  - Brewer, Maine, Forente stater, 04412
    - Lafayette Family Cancer Center-EMMC
  - Kennebunk, Maine, Forente stater, 04043
    - Maine Center for Cancer Medicine-Kennebunk
  - Sanford, Maine, Forente stater, 04073
    - MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford
  - Scarborough, Maine, Forente stater, 04074
    - Maine Center for Cancer Medicine-Scarborough
  - South Portland, Maine, Forente stater, 04106
    - Maine Medical Partners - South Portland
  - Topsham, Maine, Forente stater, 04086
    - Maine Center for Cancer Medicine-Topsham
  - York Village, Maine, Forente stater, 03909
    - York Hospital
- Maryland
  - Annapolis, Maryland, Forente stater, 21401
    - Luminis Health Anne Arundel Medical Center
  - Baltimore, Maryland, Forente stater, 21237
    - MedStar Franklin Square Medical Center/Weinberg Cancer Institute
  - Baltimore, Maryland, Forente stater, 21287
    - Johns Hopkins University/Sidney Kimmel Cancer Center
  - Baltimore, Maryland, Forente stater, 21215
    - Sinai Hospital of Baltimore
  - Baltimore, Maryland, Forente stater, 21204
    - Greater Baltimore Medical Center
  - Baltimore, Maryland, Forente stater, 21244
    - Kaiser Permanente-Woodlawn Medical Center
  - Baltimore, Maryland, Forente stater, 21239
    - MedStar Good Samaritan Hospital
  - Bel Air, Maryland, Forente stater, 21014
    - UM Upper Chesapeake Medical Center
  - Bethesda, Maryland, Forente stater, 20889-5600
    - Walter Reed National Military Medical Center
  - Cumberland, Maryland, Forente stater, 21502
    - UPMC Western Maryland
  - Easton, Maryland, Forente stater, 21601
    - University of Maryland Shore Medical Center at Easton
  - Gaithersburg, Maryland, Forente stater, 20879
    - Kaiser Permanente-Gaithersburg Medical Center
  - Kensington, Maryland, Forente stater, 20895
    - Kaiser Permanente - Kensington Medical Center
  - Largo, Maryland, Forente stater, 20774
    - Kaiser Permanente - Largo Medical Center
  - Lutherville, Maryland, Forente stater, 21093
    - Kaiser Permanente Lutherville - Timonium Medical Center
  - Olney, Maryland, Forente stater, 20832
    - Medstar Montgomery Medical Center
  - Westminster, Maryland, Forente stater, 21157
    - William E Kahlert Regional Cancer Center/Sinai Hospital
- Massachusetts
  - Beverly, Massachusetts, Forente stater, 01915
    - Beverly Hospital
  - Boston, Massachusetts, Forente stater, 02215
    - Beth Israel Deaconess Medical Center
  - Boston, Massachusetts, Forente stater, 02215
    - Dana-Farber Cancer Institute
  - Boston, Massachusetts, Forente stater, 02111
    - Tufts Medical Center
  - Boston, Massachusetts, Forente stater, 02118
    - Boston Medical Center
  - Burlington, Massachusetts, Forente stater, 01805
    - Lahey Hospital and Medical Center
  - Foxborough, Massachusetts, Forente stater, 02035
    - Dana-Farber Cancer Institute at Foxborough
  - Gloucester, Massachusetts, Forente stater, 01930
    - Addison Gilbert Hospital
  - Hyannis, Massachusetts, Forente stater, 02601
    - Cape Cod Hospital
  - Lowell, Massachusetts, Forente stater, 01854
    - Lowell General Hospital
  - Milford, Massachusetts, Forente stater, 01757
    - Dana-Farber/Brigham and Women's Cancer Center at Milford Regional
  - Peabody, Massachusetts, Forente stater, 01960
    - Lahey Medical Center-Peabody
  - South Weymouth, Massachusetts, Forente stater, 02190
    - Dana-Farber/Brigham and Women's Cancer Center at South Shore
  - Winchester, Massachusetts, Forente stater, 01890
    - Winchester Hospital
  - Worcester, Massachusetts, Forente stater, 01655
    - UMass Memorial Medical Center - University Campus
- Michigan
  - Adrian, Michigan, Forente stater, 49221
    - Hickman Cancer Center
  - Ann Arbor, Michigan, Forente stater, 48109
    - University Of Michigan Comprehensive Cancer Center
  - Ann Arbor, Michigan, Forente stater, 48106
    - Trinity Health Saint Joseph Mercy Hospital Ann Arbor
  - Battle Creek, Michigan, Forente stater, 49017
    - Bronson Battle Creek
  - Brighton, Michigan, Forente stater, 48114
    - Trinity Health IHA Medical Group Hematology Oncology - Brighton
  - Brighton, Michigan, Forente stater, 48114
    - Trinity Health Medical Center - Brighton
  - Canton, Michigan, Forente stater, 48188
    - Trinity Health IHA Medical Group Hematology Oncology - Canton
  - Canton, Michigan, Forente stater, 48188
    - Trinity Health Medical Center - Canton
  - Caro, Michigan, Forente stater, 48723
    - Caro Cancer Center
  - Chelsea, Michigan, Forente stater, 48118
    - Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
  - Chelsea, Michigan, Forente stater, 48118
    - Chelsea Hospital
  - Clarkston, Michigan, Forente stater, 48346
    - Hematology Oncology Consultants-Clarkston
  - Clarkston, Michigan, Forente stater, 48346
    - Newland Medical Associates-Clarkston
  - Dearborn, Michigan, Forente stater, 48124
    - Corewell Health Dearborn Hospital
  - Detroit, Michigan, Forente stater, 48201
    - Wayne State University/Karmanos Cancer Institute
  - Detroit, Michigan, Forente stater, 48236
    - Ascension Saint John Hospital
  - East China, Michigan, Forente stater, 48054
    - Great Lakes Cancer Management Specialists-Doctors Park
  - Farmington Hills, Michigan, Forente stater, 48334
    - Weisberg Cancer Treatment Center
  - Farmington Hills, Michigan, Forente stater, 48336
    - Corewell Health Farmington Hills Hospital
  - Flint, Michigan, Forente stater, 48503
    - Hurley Medical Center
  - Flint, Michigan, Forente stater, 48503
    - Genesee Cancer and Blood Disease Treatment Center
  - Flint, Michigan, Forente stater, 48503
    - Genesee Hematology Oncology PC
  - Flint, Michigan, Forente stater, 48503
    - Genesys Hurley Cancer Institute
  - Grand Rapids, Michigan, Forente stater, 49503
    - Trinity Health Grand Rapids Hospital
  - Grand Rapids, Michigan, Forente stater, 49503
    - Corewell Health Grand Rapids Hospitals - Butterworth Hospital
  - Grosse Pointe Woods, Michigan, Forente stater, 48236
    - Academic Hematology Oncology Specialists
  - Grosse Pointe Woods, Michigan, Forente stater, 48236
    - Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
  - Grosse Pointe Woods, Michigan, Forente stater, 48236
    - Michigan Breast Specialists-Grosse Pointe Woods
  - Kalamazoo, Michigan, Forente stater, 49007
    - West Michigan Cancer Center
  - Kalamazoo, Michigan, Forente stater, 49007
    - Bronson Methodist Hospital
  - Kalamazoo, Michigan, Forente stater, 49009
    - Ascension Borgess Cancer Center
  - Lansing, Michigan, Forente stater, 48912
    - University of Michigan Health - Sparrow Lansing
  - Livonia, Michigan, Forente stater, 48154
    - Trinity Health Saint Mary Mercy Livonia Hospital
  - Livonia, Michigan, Forente stater, 48154
    - Hope Cancer Clinic
  - Macomb, Michigan, Forente stater, 48044
    - Great Lakes Cancer Management Specialists-Macomb Medical Campus
  - Macomb, Michigan, Forente stater, 48044
    - Michigan Breast Specialists-Macomb Township
  - Marlette, Michigan, Forente stater, 48453
    - Saint Mary's Oncology/Hematology Associates of Marlette
  - Midland, Michigan, Forente stater, 48670
    - MyMichigan Medical Center Midland
  - Monroe, Michigan, Forente stater, 48162
    - Toledo Clinic Cancer Centers-Monroe
  - Muskegon, Michigan, Forente stater, 49444
    - Trinity Health Muskegon Hospital
  - Niles, Michigan, Forente stater, 49120
    - Corewell Health Lakeland Hospitals - Niles Hospital
  - Norton Shores, Michigan, Forente stater, 49444
    - Cancer and Hematology Centers of Western Michigan - Norton Shores
  - Novi, Michigan, Forente stater, 48374
    - Ascension Providence Hospitals - Novi
  - Pontiac, Michigan, Forente stater, 48341
    - Hope Cancer Center
  - Pontiac, Michigan, Forente stater, 48341
    - Newland Medical Associates-Pontiac
  - Pontiac, Michigan, Forente stater, 48341
    - Trinity Health Saint Joseph Mercy Oakland Hospital
  - Pontiac, Michigan, Forente stater, 48341
    - Michigan Healthcare Professionals Pontiac
  - Reed City, Michigan, Forente stater, 49677
    - Corewell Health Reed City Hospital
  - Royal Oak, Michigan, Forente stater, 48073
    - Corewell Health William Beaumont University Hospital
  - Saginaw, Michigan, Forente stater, 48601
    - Ascension Saint Mary's Hospital
  - Saginaw, Michigan, Forente stater, 48604
    - Oncology Hematology Associates of Saginaw Valley PC
  - Saint Joseph, Michigan, Forente stater, 49085
    - Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
  - Saint Joseph, Michigan, Forente stater, 49085
    - Corewell Health Lakeland Hospitals - Saint Joseph Hospital
  - Southfield, Michigan, Forente stater, 48075
    - Ascension Providence Hospitals - Southfield
  - Sterling Heights, Michigan, Forente stater, 48312
    - Bhadresh Nayak MD PC-Sterling Heights
  - Tawas City, Michigan, Forente stater, 48764
    - Ascension Saint Joseph Hospital
  - Traverse City, Michigan, Forente stater, 49684
    - Munson Medical Center
  - Troy, Michigan, Forente stater, 48085
    - Corewell Health Beaumont Troy Hospital
  - Warren, Michigan, Forente stater, 48093
    - Saint John Macomb-Oakland Hospital
  - Warren, Michigan, Forente stater, 48088
    - Advanced Breast Care Center PLLC
  - Warren, Michigan, Forente stater, 48093
    - Great Lakes Cancer Management Specialists-Macomb Professional Building
  - Warren, Michigan, Forente stater, 48093
    - Macomb Hematology Oncology PC
  - Warren, Michigan, Forente stater, 48093
    - Michigan Breast Specialists-Warren
  - West Branch, Michigan, Forente stater, 48661
    - Saint Mary's Oncology/Hematology Associates of West Branch
  - Wyoming, Michigan, Forente stater, 49519
    - University of Michigan Health - West
  - Ypsilanti, Michigan, Forente stater, 48197
    - Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
  - Ypsilanti, Michigan, Forente stater, 48106
    - Huron Gastroenterology PC
- Minnesota
  - Aitkin, Minnesota, Forente stater, 56431
    - Riverwood Healthcare Center
  - Bemidji, Minnesota, Forente stater, 56601
    - Sanford Joe Lueken Cancer Center
  - Brainerd, Minnesota, Forente stater, 56401
    - Essentia Health Saint Joseph's Medical Center
  - Burnsville, Minnesota, Forente stater, 55337
    - Fairview Ridges Hospital
  - Burnsville, Minnesota, Forente stater, 55337
    - Minnesota Oncology - Burnsville
  - Cambridge, Minnesota, Forente stater, 55008
    - Cambridge Medical Center
  - Coon Rapids, Minnesota, Forente stater, 55433
    - Mercy Hospital
  - Deer River, Minnesota, Forente stater, 56636
    - Essentia Health - Deer River Clinic
  - Detroit Lakes, Minnesota, Forente stater, 56501
    - Essentia Health Saint Mary's - Detroit Lakes Clinic
  - Duluth, Minnesota, Forente stater, 55805
    - Saint Luke's Hospital of Duluth
  - Duluth, Minnesota, Forente stater, 55805
    - Essentia Health Cancer Center
  - Duluth, Minnesota, Forente stater, 55805
    - Essentia Health Saint Mary's Medical Center
  - Duluth, Minnesota, Forente stater, 55805
    - Miller-Dwan Hospital
  - Edina, Minnesota, Forente stater, 55435
    - Fairview Southdale Hospital
  - Fergus Falls, Minnesota, Forente stater, 56537
    - Lake Region Healthcare Corporation-Cancer Care
  - Fosston, Minnesota, Forente stater, 56542
    - Essentia Health - Fosston
  - Fridley, Minnesota, Forente stater, 55432
    - Unity Hospital
  - Hibbing, Minnesota, Forente stater, 55746
    - Essentia Health Hibbing Clinic
  - Maple Grove, Minnesota, Forente stater, 55369
    - Fairview Clinics and Surgery Center Maple Grove
  - Maplewood, Minnesota, Forente stater, 55109
    - Saint John's Hospital - Healtheast
  - Maplewood, Minnesota, Forente stater, 55109
    - Minnesota Oncology Hematology PA-Maplewood
  - Minneapolis, Minnesota, Forente stater, 55415
    - Hennepin County Medical Center
  - Minneapolis, Minnesota, Forente stater, 55407
    - Abbott-Northwestern Hospital
  - Minneapolis, Minnesota, Forente stater, 55454
    - Health Partners Inc
  - Monticello, Minnesota, Forente stater, 55362
    - Monticello Cancer Center
  - New Ulm, Minnesota, Forente stater, 56073
    - New Ulm Medical Center
  - Park Rapids, Minnesota, Forente stater, 56470
    - Essentia Health - Park Rapids
  - Princeton, Minnesota, Forente stater, 55371
    - Fairview Northland Medical Center
  - Robbinsdale, Minnesota, Forente stater, 55422
    - North Memorial Medical Health Center
  - Rochester, Minnesota, Forente stater, 55905
    - Mayo Clinic in Rochester
  - Saint Cloud, Minnesota, Forente stater, 56303
    - Coborn Cancer Center at Saint Cloud Hospital
  - Saint Louis Park, Minnesota, Forente stater, 55416
    - Park Nicollet Clinic - Saint Louis Park
  - Saint Paul, Minnesota, Forente stater, 55101
    - Regions Hospital
  - Saint Paul, Minnesota, Forente stater, 55102
    - United Hospital
  - Sandstone, Minnesota, Forente stater, 55072
    - Essentia Health Sandstone
  - Shakopee, Minnesota, Forente stater, 55379
    - Saint Francis Regional Medical Center
  - Stillwater, Minnesota, Forente stater, 55082
    - Lakeview Hospital
  - Thief River Falls, Minnesota, Forente stater, 56701
    - Sanford Thief River Falls Medical Center
  - Virginia, Minnesota, Forente stater, 55792
    - Essentia Health Virginia Clinic
  - Waconia, Minnesota, Forente stater, 55387
    - Ridgeview Medical Center
  - Willmar, Minnesota, Forente stater, 56201
    - Rice Memorial Hospital
  - Woodbury, Minnesota, Forente stater, 55125
    - Minnesota Oncology Hematology PA-Woodbury
  - Worthington, Minnesota, Forente stater, 56187
    - Sanford Cancer Center Worthington
  - Wyoming, Minnesota, Forente stater, 55092
    - Fairview Lakes Medical Center
- Mississippi
  - Columbus, Mississippi, Forente stater, 39705
    - Baptist Memorial Hospital and Cancer Center-Golden Triangle
  - Grenada, Mississippi, Forente stater, 38901
    - Baptist Cancer Center-Grenada
  - Jackson, Mississippi, Forente stater, 39216
    - University of Mississippi Medical Center
  - New Albany, Mississippi, Forente stater, 38652
    - Baptist Memorial Hospital and Cancer Center-Union County
  - Oxford, Mississippi, Forente stater, 38655
    - Baptist Memorial Hospital and Cancer Center-Oxford
  - Southhaven, Mississippi, Forente stater, 38671
    - Baptist Memorial Hospital and Cancer Center-Desoto
- Missouri
  - Ballwin, Missouri, Forente stater, 63011
    - Saint Louis Cancer and Breast Institute-Ballwin
  - Bolivar, Missouri, Forente stater, 65613
    - Central Care Cancer Center - Bolivar
  - Cape Girardeau, Missouri, Forente stater, 63703
    - Saint Francis Medical Center
  - Cape Girardeau, Missouri, Forente stater, 63703
    - Southeast Cancer Center
  - Chesterfield, Missouri, Forente stater, 63017
    - Saint Luke's Hospital
  - City of Saint Peters, Missouri, Forente stater, 63376
    - Siteman Cancer Center at Saint Peters Hospital
  - Columbia, Missouri, Forente stater, 65212
    - MU Health - University Hospital/Ellis Fischel Cancer Center
  - Creve Coeur, Missouri, Forente stater, 63141
    - Siteman Cancer Center at West County Hospital
  - Farmington, Missouri, Forente stater, 63640
    - Parkland Health Center - Farmington
  - Independence, Missouri, Forente stater, 64057
    - Centerpoint Medical Center LLC
  - Jefferson City, Missouri, Forente stater, 65109
    - MU Health Care Goldschmidt Cancer Center
  - Joplin, Missouri, Forente stater, 64804
    - Freeman Health System
  - Joplin, Missouri, Forente stater, 64804
    - Mercy Hospital Joplin
  - Kansas City, Missouri, Forente stater, 64154
    - University of Kansas Cancer Center - North
  - Kansas City, Missouri, Forente stater, 64111
    - Saint Luke's Hospital of Kansas City
  - Kansas City, Missouri, Forente stater, 64132
    - Research Medical Center
  - Kansas City, Missouri, Forente stater, 64108
    - University Health Truman Medical Center
  - Lee's Summit, Missouri, Forente stater, 64064
    - University of Kansas Cancer Center - Lee's Summit
  - Lee's Summit, Missouri, Forente stater, 64086
    - Saint Luke's East - Lee's Summit
  - North Kansas City, Missouri, Forente stater, 64116
    - University of Kansas Cancer Center at North Kansas City Hospital
  - Rolla, Missouri, Forente stater, 65401
    - Delbert Day Cancer Institute at PCRMC
  - Rolla, Missouri, Forente stater, 65401
    - Mercy Clinic-Rolla-Cancer and Hematology
  - Saint Joseph, Missouri, Forente stater, 64506
    - Heartland Regional Medical Center
  - Sainte Genevieve, Missouri, Forente stater, 63670
    - Sainte Genevieve County Memorial Hospital
  - Springfield, Missouri, Forente stater, 65807
    - CoxHealth South Hospital
  - Springfield, Missouri, Forente stater, 65804
    - Mercy Hospital Springfield
  - St Louis, Missouri, Forente stater, 63110
    - Washington University School of Medicine
  - St Louis, Missouri, Forente stater, 63129
    - Siteman Cancer Center-South County
  - St Louis, Missouri, Forente stater, 63136
    - Siteman Cancer Center at Christian Hospital
  - St Louis, Missouri, Forente stater, 63131
    - Missouri Baptist Medical Center
  - St Louis, Missouri, Forente stater, 63141
    - Mercy Hospital Saint Louis
  - St Louis, Missouri, Forente stater, 63128
    - Mercy Hospital South
  - St Louis, Missouri, Forente stater, 63109
    - Saint Louis Cancer and Breast Institute-South City
  - Sullivan, Missouri, Forente stater, 63080
    - Missouri Baptist Sullivan Hospital
  - Sunset Hills, Missouri, Forente stater, 63127
    - BJC Outpatient Center at Sunset Hills
  - Washington, Missouri, Forente stater, 63090
    - Mercy Hospital Washington
- Montana
  - Anaconda, Montana, Forente stater, 59711
    - Community Hospital of Anaconda
  - Billings, Montana, Forente stater, 59101
    - Billings Clinic Cancer Center
  - Billings, Montana, Forente stater, 59101
    - Saint Vincent Healthcare
  - Billings, Montana, Forente stater, 59102
    - Saint Vincent Frontier Cancer Center
  - Bozeman, Montana, Forente stater, 59715
    - Bozeman Health Deaconess Hospital
  - Butte, Montana, Forente stater, 59701
    - Saint James Community Hospital and Cancer Treatment Center
  - Great Falls, Montana, Forente stater, 59405
    - Great Falls Clinic
  - Great Falls, Montana, Forente stater, 59405
    - Benefis Sletten Cancer Institute
  - Kalispell, Montana, Forente stater, 59901
    - Kalispell Regional Medical Center
  - Missoula, Montana, Forente stater, 59802
    - Saint Patrick Hospital - Community Hospital
  - Missoula, Montana, Forente stater, 59804
    - Community Medical Center
- Nebraska
  - Bellevue, Nebraska, Forente stater, 68123
    - Nebraska Medicine-Bellevue
  - Grand Island, Nebraska, Forente stater, 68803
    - Nebraska Cancer Specialists/Oncology Hematology West PC
  - Kearney, Nebraska, Forente stater, 68847
    - CHI Health Good Samaritan
  - Lincoln, Nebraska, Forente stater, 68510
    - Saint Elizabeth Regional Medical Center
  - Omaha, Nebraska, Forente stater, 68114
    - Nebraska Methodist Hospital
  - Omaha, Nebraska, Forente stater, 68198
    - University of Nebraska Medical Center
  - Omaha, Nebraska, Forente stater, 68124
    - Alegent Health Bergan Mercy Medical Center
  - Omaha, Nebraska, Forente stater, 68118
    - Nebraska Medicine-Village Pointe
  - Omaha, Nebraska, Forente stater, 68122
    - Alegent Health Immanuel Medical Center
  - Omaha, Nebraska, Forente stater, 68130
    - Alegent Health Lakeside Hospital
  - Omaha, Nebraska, Forente stater, 68131
    - Creighton University Medical Center
  - Omaha, Nebraska, Forente stater, 68114
    - Oncology Associates PC
  - Omaha, Nebraska, Forente stater, 68114
    - Nebraska Cancer Specialists/Oncology Hematology West PC - MECC
  - Papillion, Nebraska, Forente stater, 68046
    - Midlands Community Hospital
- Nevada
  - Carson City, Nevada, Forente stater, 89703
    - Carson Tahoe Regional Medical Center
  - Henderson, Nevada, Forente stater, 89052
    - Comprehensive Cancer Centers of Nevada - Henderson
  - Henderson, Nevada, Forente stater, 89052
    - OptumCare Cancer Care at Seven Hills
  - Henderson, Nevada, Forente stater, 89052
    - Cancer and Blood Specialists-Henderson
  - Henderson, Nevada, Forente stater, 89052
    - Las Vegas Cancer Center-Henderson
  - Henderson, Nevada, Forente stater, 89074
    - Comprehensive Cancer Centers of Nevada-Southeast Henderson
  - Henderson, Nevada, Forente stater, 89074
    - GenesisCare USA - Henderson
  - Henderson, Nevada, Forente stater, 89052
    - Comprehensive Cancer Centers of Nevada-Horizon Ridge
  - Henderson, Nevada, Forente stater, 89074
    - Las Vegas Urology - Green Valley
  - Henderson, Nevada, Forente stater, 89074
    - Las Vegas Urology - Pebble
  - Henderson, Nevada, Forente stater, 89074
    - Urology Specialists of Nevada - Green Valley
  - Las Vegas, Nevada, Forente stater, 89144
    - Summerlin Hospital Medical Center
  - Las Vegas, Nevada, Forente stater, 89109
    - Sunrise Hospital and Medical Center
  - Las Vegas, Nevada, Forente stater, 89102
    - OptumCare Cancer Care at Charleston
  - Las Vegas, Nevada, Forente stater, 89106
    - Radiation Oncology Centers of Nevada Central
  - Las Vegas, Nevada, Forente stater, 89109
    - GenesisCare USA - Las Vegas
  - Las Vegas, Nevada, Forente stater, 89119
    - Radiation Oncology Centers of Nevada Southeast
  - Las Vegas, Nevada, Forente stater, 89128
    - Comprehensive Cancer Centers of Nevada - Northwest
  - Las Vegas, Nevada, Forente stater, 89128
    - OptumCare Cancer Care at MountainView
  - Las Vegas, Nevada, Forente stater, 89135
    - Alliance for Childhood Diseases/Cure 4 the Kids Foundation
  - Las Vegas, Nevada, Forente stater, 89144
    - Comprehensive Cancer Centers of Nevada - Town Center
  - Las Vegas, Nevada, Forente stater, 89144
    - Comprehensive Cancer Centers of Nevada-Summerlin
  - Las Vegas, Nevada, Forente stater, 89148
    - Comprehensive Cancer Centers of Nevada
  - Las Vegas, Nevada, Forente stater, 89148
    - OptumCare Cancer Care at Fort Apache
  - Las Vegas, Nevada, Forente stater, 89169
    - Comprehensive Cancer Centers of Nevada - Central Valley
  - Las Vegas, Nevada, Forente stater, 89102
    - University Medical Center of Southern Nevada
  - Las Vegas, Nevada, Forente stater, 89128
    - GenesisCare USA - Vegas Tenaya
  - Las Vegas, Nevada, Forente stater, 89148-2405
    - Las Vegas Cancer Center-Medical Center
  - Las Vegas, Nevada, Forente stater, 89148
    - GenesisCare USA - Fort Apache
  - Las Vegas, Nevada, Forente stater, 89128
    - Ann M Wierman MD LTD
  - Las Vegas, Nevada, Forente stater, 89074
    - Las Vegas Urology - Pecos
  - Las Vegas, Nevada, Forente stater, 89102
    - Desert West Surgery
  - Las Vegas, Nevada, Forente stater, 89103
    - Hope Cancer Care of Nevada
  - Las Vegas, Nevada, Forente stater, 89106
    - Urology Specialists of Nevada - Central
  - Las Vegas, Nevada, Forente stater, 89113
    - Las Vegas Prostate Cancer Center
  - Las Vegas, Nevada, Forente stater, 89113
    - Las Vegas Urology - Sunset
  - Las Vegas, Nevada, Forente stater, 89128
    - Las Vegas Urology - Cathedral Rock
  - Las Vegas, Nevada, Forente stater, 89128
    - Las Vegas Urology - Smoke Ranch
  - Las Vegas, Nevada, Forente stater, 89128
    - Urology Specialists of Nevada - Northwest
  - Las Vegas, Nevada, Forente stater, 89169
    - University Cancer Center
  - Las Vegas, Nevada, Forente stater, 89113
    - Urology Specialists of Nevada - Southwest
  - Pahrump, Nevada, Forente stater, 89048
    - Hope Cancer Care of Nevada-Pahrump
  - Reno, Nevada, Forente stater, 89502
    - Renown Regional Medical Center
  - Reno, Nevada, Forente stater, 89503
    - Saint Mary's Regional Medical Center
  - Reno, Nevada, Forente stater, 89509
    - Radiation Oncology Associates
- New Hampshire
  - Concord, New Hampshire, Forente stater, 03301
    - New Hampshire Oncology Hematology PA-Concord
  - Lebanon, New Hampshire, Forente stater, 03756
    - Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
  - Manchester, New Hampshire, Forente stater, 03103
    - Solinsky Center for Cancer Care
- New Jersey
  - Berkeley Heights, New Jersey, Forente stater, 07922
    - Summit Medical Group
  - Camden, New Jersey, Forente stater, 08103
    - Cooper Hospital University Medical Center
  - Englewood, New Jersey, Forente stater, 07631
    - Englewood Hospital and Medical Center
  - Florham Park, New Jersey, Forente stater, 07932
    - Summit Health - Florham Park Campus
  - Hackensack, New Jersey, Forente stater, 07601
    - Hackensack University Medical Center
  - Hamilton, New Jersey, Forente stater, 08690
    - The Cancer Institute of New Jersey Hamilton
  - Jersey City, New Jersey, Forente stater, 07302
    - Jersey City Medical Center
  - Lakewood, New Jersey, Forente stater, 08701
    - Monmouth Medical Center Southern Campus
  - Livingston, New Jersey, Forente stater, 07039
    - Saint Barnabas Medical Center
  - Long Branch, New Jersey, Forente stater, 07740
    - Monmouth Medical Center
  - Morristown, New Jersey, Forente stater, 07960
    - Morristown Medical Center
  - New Brunswick, New Jersey, Forente stater, 08903
    - Rutgers Cancer Institute of New Jersey
  - Newark, New Jersey, Forente stater, 07101
    - Rutgers New Jersey Medical School
  - Newark, New Jersey, Forente stater, 07112
    - Newark Beth Israel Medical Center
  - Paterson, New Jersey, Forente stater, 07503
    - Saint Joseph's Regional Medical Center
  - Sewell, New Jersey, Forente stater, 08080
    - Sidney Kimmel Cancer Center Washington Township
  - Somerville, New Jersey, Forente stater, 08876
    - Robert Wood Johnson University Hospital Somerset
  - Summit, New Jersey, Forente stater, 07902
    - Overlook Hospital
  - Teaneck, New Jersey, Forente stater, 07666
    - Holy Name Hospital
  - Toms River, New Jersey, Forente stater, 08755
    - Community Medical Center
- New Mexico
  - Albuquerque, New Mexico, Forente stater, 87106
    - University of New Mexico Cancer Center
  - Albuquerque, New Mexico, Forente stater, 87110
    - Presbyterian Kaseman Hospital
  - Rio Rancho, New Mexico, Forente stater, 87124
    - Presbyterian Rust Medical Center/Jorgensen Cancer Center
- New York
  - Auburn, New York, Forente stater, 13021
    - Hematology Oncology Associates of Central New York-Auburn
  - Bay Shore, New York, Forente stater, 11706
    - Northwell Health Imbert Cancer Center
  - Buffalo, New York, Forente stater, 14263
    - Roswell Park Cancer Institute
  - East Hills, New York, Forente stater, 11548
    - The Cancer Institute at Saint Francis Hospital
  - East Syracuse, New York, Forente stater, 13057
    - Hematology Oncology Associates of Central New York-East Syracuse
  - Glens Falls, New York, Forente stater, 12801
    - Glens Falls Hospital
  - Jamaica, New York, Forente stater, 11432
    - Queens Hospital Center
  - Lake Success, New York, Forente stater, 11042
    - Northwell Health/Center for Advanced Medicine
  - Mineola, New York, Forente stater, 11501
    - NYU Langone Hospital - Long Island
  - Mount Kisco, New York, Forente stater, 10549
    - Northern Westchester Hospital
  - New York, New York, Forente stater, 10019
    - Mount Sinai West
  - New York, New York, Forente stater, 10029
    - Mount Sinai Hospital
  - New York, New York, Forente stater, 10032
    - NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
  - New York, New York, Forente stater, 10011
    - Mount Sinai Chelsea
  - New York, New York, Forente stater, 10016
    - Laura and Isaac Perlmutter Cancer Center at NYU Langone
  - New York, New York, Forente stater, 10021
    - Lenox Hill Hospital
  - New York, New York, Forente stater, 10065
    - Manhattan Eye Ear and Throat Hospital
  - Nyack, New York, Forente stater, 10960
    - Nyack Hospital
  - Poughkeepsie, New York, Forente stater, 12601
    - Vassar Brothers Medical Center
  - Rochester, New York, Forente stater, 14642
    - University of Rochester
  - Rochester, New York, Forente stater, 14623
    - Pluta Cancer Center
  - Sleepy Hollow, New York, Forente stater, 10591
    - Phelps Memorial Hospital Center
  - Stony Brook, New York, Forente stater, 11794
    - Stony Brook University Medical Center
  - Syracuse, New York, Forente stater, 13210
    - State University of New York Upstate Medical University
  - Syracuse, New York, Forente stater, 13215
    - Hematology Oncology Associates of Central New York-Onondaga Hill
  - Verona, New York, Forente stater, 13478
    - Upstate Cancer Center at Verona
  - West Islip, New York, Forente stater, 11795
    - Good Samaritan University Hospital
  - White Plains, New York, Forente stater, 10601
    - Dickstein Cancer Treatment Center
- North Carolina
  - Asheboro, North Carolina, Forente stater, 27203
    - Randolph Hospital
  - Asheboro, North Carolina, Forente stater, 27203
    - Cone Health Cancer Center at Asheboro
  - Asheboro, North Carolina, Forente stater, 27203
    - Randolph Health Cancer Center
  - Burlington, North Carolina, Forente stater, 27215
    - Cone Health Cancer Center at Alamance Regional
  - Cary, North Carolina, Forente stater, 27518
    - Rex Hematology Oncology Associates-Cary
  - Chapel Hill, North Carolina, Forente stater, 27599
    - UNC Lineberger Comprehensive Cancer Center
  - Charlotte, North Carolina, Forente stater, 28204
    - Novant Health Presbyterian Medical Center
  - Clinton, North Carolina, Forente stater, 28328
    - Southeastern Medical Oncology Center-Clinton
  - Durham, North Carolina, Forente stater, 27710
    - Duke University Medical Center
  - Garner, North Carolina, Forente stater, 27529
    - Rex Hematology Oncology Associates-Garner
  - Gastonia, North Carolina, Forente stater, 28054
    - CaroMont Regional Medical Center
  - Goldsboro, North Carolina, Forente stater, 27534
    - Southeastern Medical Oncology Center-Goldsboro
  - Greensboro, North Carolina, Forente stater, 27403
    - Cone Health Cancer Center
  - Greensboro, North Carolina, Forente stater, 27410
    - Cone Health Cancer Center at Drawbridge Parkway
  - Greensboro, North Carolina, Forente stater, 27403
    - Novant Health Breast Surgery - Greensboro
  - Hillsborough, North Carolina, Forente stater, 27278
    - University of North Carolina-Hillsborough Campus
  - Huntersville, North Carolina, Forente stater, 28078
    - Novant Health Cancer Institute - Huntersville
  - Jacksonville, North Carolina, Forente stater, 28546
    - Southeastern Medical Oncology Center-Jacksonville
  - Kernersville, North Carolina, Forente stater, 27284
    - Novant Health Cancer Institute - Kernersville
  - Kinston, North Carolina, Forente stater, 28501
    - ECU Health Oncology Kinston
  - Matthews, North Carolina, Forente stater, 28105
    - Matthews Radiation Oncology Center
  - Matthews, North Carolina, Forente stater, 28105
    - Novant Health Cancer Institute - Matthews
  - Mebane, North Carolina, Forente stater, 27302
    - Cone Heath Cancer Center at Mebane
  - Mooresville, North Carolina, Forente stater, 28117
    - Novant Health Cancer Institute - Mooresville
  - Mount Airy, North Carolina, Forente stater, 27030
    - Novant Health Cancer Institute - Mount Airy
  - North Wilkesboro, North Carolina, Forente stater, 28659
    - Novant Health Cancer Institute - Wilkesboro
  - Pinehurst, North Carolina, Forente stater, 28374
    - FirstHealth of the Carolinas-Moore Regional Hospital
  - Raleigh, North Carolina, Forente stater, 27607
    - UNC Rex Healthcare
  - Raleigh, North Carolina, Forente stater, 27614
    - UNC Rex Cancer Center of Wakefield
  - Raleigh, North Carolina, Forente stater, 27607
    - Duke Women's Cancer Care Raleigh
  - Raleigh, North Carolina, Forente stater, 27607
    - Rex Hematology Oncology Associates-Blue Ridge
  - Reidsville, North Carolina, Forente stater, 27320
    - Annie Penn Memorial Hospital
  - Salisbury, North Carolina, Forente stater, 28144
    - Novant Health Cancer Institute - Rowan
  - Stateville, North Carolina, Forente stater, 28625
    - Novant Health Cancer Institute - Statesville
  - Thomasville, North Carolina, Forente stater, 27360
    - Novant Health Cancer Institute - Thomasville
  - Winston-Salem, North Carolina, Forente stater, 27103
    - Novant Health Forsyth Medical Center
- North Dakota
  - Bismarck, North Dakota, Forente stater, 58501
    - Sanford Bismarck Medical Center
  - Fargo, North Dakota, Forente stater, 58122
    - Sanford Roger Maris Cancer Center
  - Fargo, North Dakota, Forente stater, 58103
    - Essentia Health Cancer Center-South University Clinic
  - Fargo, North Dakota, Forente stater, 58122
    - Sanford Broadway Medical Center
  - Fargo, North Dakota, Forente stater, 58103
    - Sanford South University Medical Center
  - Fargo, North Dakota, Forente stater, 58103
    - Southpointe-Sanford Medical Center Fargo
  - Fargo, North Dakota, Forente stater, 58104
    - Sanford Medical Center Fargo
  - Jamestown, North Dakota, Forente stater, 58401
    - Essentia Health - Jamestown Clinic
- Ohio
  - Alliance, Ohio, Forente stater, 44601
    - Aultman Alliance Community Hospital
  - Beavercreek, Ohio, Forente stater, 45431
    - Indu and Raj Soin Medical Center
  - Belpre, Ohio, Forente stater, 45714
    - Strecker Cancer Center-Belpre
  - Boardman, Ohio, Forente stater, 44512
    - Saint Elizabeth Boardman Hospital
  - Canton, Ohio, Forente stater, 44708
    - Cleveland Clinic Mercy Hospital
  - Canton, Ohio, Forente stater, 44710
    - Aultman Health Foundation
  - Canton, Ohio, Forente stater, 44708
    - Mercy Hematology and Oncology Associates Inc
  - Centerville, Ohio, Forente stater, 45459
    - Miami Valley Hospital South
  - Centerville, Ohio, Forente stater, 45459
    - Dayton Physicians LLC-Miami Valley South
  - Chillicothe, Ohio, Forente stater, 45601
    - Adena Regional Medical Center
  - Cincinnati, Ohio, Forente stater, 45219
    - The Christ Hospital
  - Cincinnati, Ohio, Forente stater, 45220
    - Good Samaritan Hospital - Cincinnati
  - Cincinnati, Ohio, Forente stater, 45242
    - Bethesda North Hospital
  - Cincinnati, Ohio, Forente stater, 45236
    - Oncology Hematology Care Inc-Kenwood
  - Cincinnati, Ohio, Forente stater, 45247
    - TriHealth Cancer Institute-Westside
  - Cincinnati, Ohio, Forente stater, 45255
    - TriHealth Cancer Institute-Anderson
  - Columbus, Ohio, Forente stater, 43214
    - Riverside Methodist Hospital
  - Columbus, Ohio, Forente stater, 43210
    - Ohio State University Comprehensive Cancer Center
  - Columbus, Ohio, Forente stater, 43219
    - The Mark H Zangmeister Center
  - Columbus, Ohio, Forente stater, 43214
    - Columbus Oncology and Hematology Associates Inc
  - Columbus, Ohio, Forente stater, 43228
    - Doctors Hospital
  - Columbus, Ohio, Forente stater, 43213
    - Mount Carmel East Hospital
  - Columbus, Ohio, Forente stater, 43215
    - Grant Medical Center
  - Columbus, Ohio, Forente stater, 43222
    - Mount Carmel Health Center West
  - Dayton, Ohio, Forente stater, 45409
    - Miami Valley Hospital
  - Dayton, Ohio, Forente stater, 45415
    - Miami Valley Hospital North
  - Dayton, Ohio, Forente stater, 45415
    - Dayton Physician LLC - Englewood
  - Dayton, Ohio, Forente stater, 45409
    - Premier Blood and Cancer Center
  - Delaware, Ohio, Forente stater, 43015
    - Delaware Health Center-Grady Cancer Center
  - Delaware, Ohio, Forente stater, 43015
    - Grady Memorial Hospital
  - Dublin, Ohio, Forente stater, 43016
    - Dublin Methodist Hospital
  - Dublin, Ohio, Forente stater, 43016
    - Columbus Oncology and Hematology Associates
  - Findlay, Ohio, Forente stater, 45840
    - Blanchard Valley Hospital
  - Findlay, Ohio, Forente stater, 45840
    - Armes Family Cancer Center
  - Findlay, Ohio, Forente stater, 45840
    - Orion Cancer Care
  - Franklin, Ohio, Forente stater, 45005-1066
    - Atrium Medical Center-Middletown Regional Hospital
  - Franklin, Ohio, Forente stater, 45005
    - Dayton Physicians LLC-Atrium
  - Gahanna, Ohio, Forente stater, 43230
    - Central Ohio Breast and Endocrine Surgery
  - Greenville, Ohio, Forente stater, 45331
    - Wayne Hospital
  - Greenville, Ohio, Forente stater, 45331
    - Dayton Physicians LLC-Wayne
  - Greenville, Ohio, Forente stater, 45331
    - Miami Valley Cancer Care and Infusion
  - Grove City, Ohio, Forente stater, 43123
    - Mount Carmel Grove City Hospital
  - Kettering, Ohio, Forente stater, 45429
    - Kettering Medical Center
  - Kettering, Ohio, Forente stater, 45409
    - Greater Dayton Cancer Center
  - Lancaster, Ohio, Forente stater, 43130
    - Fairfield Medical Center
  - Lima, Ohio, Forente stater, 45801
    - Saint Rita's Medical Center
  - Mansfield, Ohio, Forente stater, 44903
    - OhioHealth Mansfield Hospital
  - Marietta, Ohio, Forente stater, 45750
    - Marietta Memorial Hospital
  - Marion, Ohio, Forente stater, 43302
    - OhioHealth Marion General Hospital
  - Marysville, Ohio, Forente stater, 43040
    - Memorial Hospital
  - Mount Vernon, Ohio, Forente stater, 43050
    - Knox Community Hospital
  - Newark, Ohio, Forente stater, 43055
    - Licking Memorial Hospital
  - Newark, Ohio, Forente stater, 43055
    - Newark Radiation Oncology
  - Portsmouth, Ohio, Forente stater, 45662
    - Southern Ohio Medical Center
  - Springfield, Ohio, Forente stater, 45504
    - Springfield Regional Cancer Center
  - Springfield, Ohio, Forente stater, 45504
    - Springfield Regional Medical Center
  - Steubenville, Ohio, Forente stater, 43952
    - Trinity's Tony Teramana Cancer Center
  - Sylvania, Ohio, Forente stater, 43560
    - ProMedica Flower Hospital
  - Toledo, Ohio, Forente stater, 43623
    - Mercy Health - Saint Anne Hospital
  - Toledo, Ohio, Forente stater, 43623
    - Toledo Clinic Cancer Centers-Toledo
  - Toledo, Ohio, Forente stater, 43608
    - Mercy Health - Saint Vincent Hospital
  - Troy, Ohio, Forente stater, 45373
    - Upper Valley Medical Center
  - Troy, Ohio, Forente stater, 45373
    - Dayton Physicians LLC - Troy
  - Warren, Ohio, Forente stater, 44484
    - Saint Joseph Warren Hospital
  - Westerville, Ohio, Forente stater, 43081
    - Saint Ann's Hospital
  - Youngstown, Ohio, Forente stater, 44501
    - Saint Elizabeth Youngstown Hospital
  - Zanesville, Ohio, Forente stater, 43701
    - Genesis Healthcare System Cancer Care Center
- Oklahoma
  - Lawton, Oklahoma, Forente stater, 73505
    - Cancer Centers of Southwest Oklahoma Research
  - Oklahoma City, Oklahoma, Forente stater, 73104
    - University of Oklahoma Health Sciences Center
  - Oklahoma City, Oklahoma, Forente stater, 73120
    - Mercy Hospital Oklahoma City
  - Oklahoma City, Oklahoma, Forente stater, 73109
    - Integris Southwest Medical Center
  - Oklahoma City, Oklahoma, Forente stater, 73142
    - Integris Cancer Institute of Oklahoma
- Oregon
  - Baker City, Oregon, Forente stater, 97814
    - Saint Alphonsus Cancer Care Center-Baker City
  - Bend, Oregon, Forente stater, 97701
    - Saint Charles Health System
  - Clackamas, Oregon, Forente stater, 97015
    - Clackamas Radiation Oncology Center
  - Clackamas, Oregon, Forente stater, 97015
    - Providence Cancer Institute Clackamas Clinic
  - Coos Bay, Oregon, Forente stater, 97420
    - Bay Area Hospital
  - Gresham, Oregon, Forente stater, 97030
    - Legacy Mount Hood Medical Center
  - Newberg, Oregon, Forente stater, 97132
    - Providence Newberg Medical Center
  - Ontario, Oregon, Forente stater, 97914
    - Saint Alphonsus Cancer Care Center-Ontario
  - Oregon City, Oregon, Forente stater, 97045
    - Providence Willamette Falls Medical Center
  - Portland, Oregon, Forente stater, 97210
    - Legacy Good Samaritan Hospital and Medical Center
  - Portland, Oregon, Forente stater, 97213
    - Providence Portland Medical Center
  - Portland, Oregon, Forente stater, 97225
    - Providence Saint Vincent Medical Center
  - Redmond, Oregon, Forente stater, 97756
    - Saint Charles Health System-Redmond
  - Tualatin, Oregon, Forente stater, 97062
    - Legacy Meridian Park Hospital
- Pennsylvania
  - Allentown, Pennsylvania, Forente stater, 18103
    - Lehigh Valley Hospital-Cedar Crest
  - Altoona, Pennsylvania, Forente stater, 16601
    - UPMC Altoona
  - Beaver, Pennsylvania, Forente stater, 15009
    - UPMC-Heritage Valley Health System Beaver
  - Bethlehem, Pennsylvania, Forente stater, 18017
    - Lehigh Valley Hospital - Muhlenberg
  - Broomall, Pennsylvania, Forente stater, 19008
    - Crozer-Keystone Regional Cancer Center at Broomall
  - Bryn Mawr, Pennsylvania, Forente stater, 19010
    - Bryn Mawr Hospital
  - Butler, Pennsylvania, Forente stater, 16001
    - UPMC Hillman Cancer Center at Butler Health System
  - Camp Hill, Pennsylvania, Forente stater, 17011
    - UPMC Camp Hill
  - Carlisle, Pennsylvania, Forente stater, 17015
    - Carlisle Regional Cancer Center
  - Chadds Ford, Pennsylvania, Forente stater, 19317
    - Christiana Care Health System-Concord Health Center
  - Chambersburg, Pennsylvania, Forente stater, 17201
    - Chambersburg Hospital
  - Chambersburg, Pennsylvania, Forente stater, 17201
    - WellSpan Medical Oncology and Hematology
  - Collegeville, Pennsylvania, Forente stater, 19426
    - Main Line Health Center-Collegeville
  - Cranberry Township, Pennsylvania, Forente stater, 16066
    - UPMC Hillman Cancer Center - Passavant - Cranberry
  - Danville, Pennsylvania, Forente stater, 17822
    - Geisinger Medical Center
  - Drexel Hill, Pennsylvania, Forente stater, 19026
    - Delaware County Memorial Hospital
  - East Norriton, Pennsylvania, Forente stater, 19401
    - Fox Chase Cancer Center - East Norriton Hospital Outpatient Center
  - East Stroudsburg, Pennsylvania, Forente stater, 18301
    - Pocono Medical Center
  - Ephrata, Pennsylvania, Forente stater, 17522
    - Ephrata Cancer Center
  - Ephrata, Pennsylvania, Forente stater, 17522
    - Ephrata Community Hospital
  - Erie, Pennsylvania, Forente stater, 16505
    - UPMC Hillman Cancer Center Erie
  - Exton, Pennsylvania, Forente stater, 19341
    - Main Line Health Center-Exton
  - Farrell, Pennsylvania, Forente stater, 16121
    - UPMC Cancer Center at UPMC Horizon
  - Gettysburg, Pennsylvania, Forente stater, 17325
    - Adams Cancer Center
  - Glen Mills, Pennsylvania, Forente stater, 19342
    - Crozer Regional Cancer Center at Brinton Lake
  - Greensburg, Pennsylvania, Forente stater, 15601
    - UPMC Cancer Centers - Arnold Palmer Pavilion
  - Greenville, Pennsylvania, Forente stater, 16125
    - Oncology Hematology Associates
  - Greenville, Pennsylvania, Forente stater, 16125
    - UPMC Hillman Cancer Center in Greenville/UPMC Horizon
  - Hanover, Pennsylvania, Forente stater, 17331
    - WellSpan Medical Oncology and Hematology
  - Harrisburg, Pennsylvania, Forente stater, 17109
    - UPMC Pinnacle Cancer Center/Community Osteopathic Campus
  - Hazleton, Pennsylvania, Forente stater, 18201
    - Geisinger Medical Center-Cancer Center Hazleton
  - Hazleton, Pennsylvania, Forente stater, 18201
    - Lehigh Valley Hospital-Hazleton
  - Hershey, Pennsylvania, Forente stater, 17033-0850
    - Penn State Milton S Hershey Medical Center
  - Indiana, Pennsylvania, Forente stater, 15701
    - IRMC Cancer Center
  - Johnstown, Pennsylvania, Forente stater, 15901
    - UPMC-Johnstown/John P. Murtha Regional Cancer Center
  - Lebanon, Pennsylvania, Forente stater, 17042
    - Sechler Family Cancer Center
  - Lewisburg, Pennsylvania, Forente stater, 17837
    - Geisinger Medical Oncology-Lewisburg
  - McKeesport, Pennsylvania, Forente stater, 15132
    - UPMC Cancer Center at UPMC McKeesport
  - Mechanicsburg, Pennsylvania, Forente stater, 17050
    - UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
  - Media, Pennsylvania, Forente stater, 19063
    - Riddle Memorial Hospital
  - Monroeville, Pennsylvania, Forente stater, 15146
    - UPMC Hillman Cancer Center - Monroeville
  - Moon Township, Pennsylvania, Forente stater, 15108
    - UPMC Hillman Cancer Center in Coraopolis
  - Mount Pleasant, Pennsylvania, Forente stater, 15666
    - UPMC Hillman Cancer Center - Part of Frick Hospital
  - Natrona Heights, Pennsylvania, Forente stater, 15065
    - UPMC Cancer Center-Natrona Heights
  - New Castle, Pennsylvania, Forente stater, 16105
    - UPMC Hillman Cancer Center - New Castle
  - North Huntingdon, Pennsylvania, Forente stater, 15642
    - Arnold Palmer Cancer Center Medical Oncology Norwin
  - Paoli, Pennsylvania, Forente stater, 19301
    - Paoli Memorial Hospital
  - Philadelphia, Pennsylvania, Forente stater, 19111
    - Fox Chase Cancer Center
  - Philadelphia, Pennsylvania, Forente stater, 19107
    - Thomas Jefferson University Hospital
  - Philadelphia, Pennsylvania, Forente stater, 19114
    - Jefferson Torresdale Hospital
  - Philadelphia, Pennsylvania, Forente stater, 19104
    - University of Pennsylvania/Abramson Cancer Center
  - Philadelphia, Pennsylvania, Forente stater, 19140
    - Temple University Hospital
  - Phoenixville, Pennsylvania, Forente stater, 19460
    - Phoenixville Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15213
    - UPMC-Magee Womens Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15232
    - University of Pittsburgh Cancer Institute (UPCI)
  - Pittsburgh, Pennsylvania, Forente stater, 15215
    - UPMC-Saint Margaret
  - Pittsburgh, Pennsylvania, Forente stater, 15237
    - UPMC-Passavant Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15243
    - UPMC-Saint Clair Hospital Cancer Center
  - Pittsburgh, Pennsylvania, Forente stater, 15219
    - UPMC-Mercy Hospital
  - Pottstown, Pennsylvania, Forente stater, 19464
    - Pottstown Hospital
  - Pottsville, Pennsylvania, Forente stater, 17901
    - Geisinger Cancer Services-Pottsville
  - Sayre, Pennsylvania, Forente stater, 18840
    - Guthrie Medical Group PC-Robert Packer Hospital
  - Scranton, Pennsylvania, Forente stater, 18510
    - Community Medical Center
  - Seneca, Pennsylvania, Forente stater, 16346
    - UPMC Cancer Center at UPMC Northwest
  - Uniontown, Pennsylvania, Forente stater, 15401
    - UPMC Cancer Center-Uniontown
  - Upland, Pennsylvania, Forente stater, 19013
    - Crozer-Chester Medical Center
  - Washington, Pennsylvania, Forente stater, 15301
    - UPMC Cancer Center-Washington
  - West Mifflin, Pennsylvania, Forente stater, 15122
    - UPMC West Mifflin-Cancer Center Jefferson
  - West Reading, Pennsylvania, Forente stater, 19611
    - Reading Hospital
  - Wilkes-Barre, Pennsylvania, Forente stater, 18711
    - Geisinger Wyoming Valley/Henry Cancer Center
  - Williamsport, Pennsylvania, Forente stater, 17701
    - UPMC Susquehanna
  - Williamsport, Pennsylvania, Forente stater, 17754
    - Divine Providence Hospital
  - Willow Grove, Pennsylvania, Forente stater, 19090
    - Asplundh Cancer Pavilion
  - Wynnewood, Pennsylvania, Forente stater, 19096
    - Lankenau Medical Center
  - York, Pennsylvania, Forente stater, 17403
    - WellSpan Health-York Cancer Center
  - York, Pennsylvania, Forente stater, 17403
    - WellSpan Health-York Hospital
  - York, Pennsylvania, Forente stater, 17403
    - Cancer Care Associates of York
  - York, Pennsylvania, Forente stater, 17408
    - UPMC Memorial
- Rhode Island
  - Providence, Rhode Island, Forente stater, 02903
    - Rhode Island Hospital
  - Providence, Rhode Island, Forente stater, 02905
    - Women and Infants Hospital
  - Warwick, Rhode Island, Forente stater, 02886
    - Kent Hospital
- South Carolina
  - Beaufort, South Carolina, Forente stater, 29902
    - Beaufort Memorial Hospital
  - Bluffton, South Carolina, Forente stater, 29910
    - Saint Joseph's/Candler - Bluffton Campus
  - Boiling Springs, South Carolina, Forente stater, 29316
    - Prisma Health Cancer Institute - Spartanburg
  - Charleston, South Carolina, Forente stater, 29425
    - Medical University of South Carolina
  - Easley, South Carolina, Forente stater, 29640
    - Prisma Health Cancer Institute - Easley
  - Florence, South Carolina, Forente stater, 29506
    - McLeod Regional Medical Center
  - Gaffney, South Carolina, Forente stater, 29341
    - Gibbs Cancer Center-Gaffney
  - Georgetown, South Carolina, Forente stater, 29440
    - Tidelands Georgetown Memorial Hospital
  - Greenville, South Carolina, Forente stater, 29605
    - Prisma Health Cancer Institute - Faris
  - Greenville, South Carolina, Forente stater, 29607
    - Saint Francis Cancer Center
  - Greenville, South Carolina, Forente stater, 29615
    - Prisma Health Cancer Institute - Eastside
  - Greenville, South Carolina, Forente stater, 29605
    - Prisma Health Cancer Institute - Butternut
  - Greenville, South Carolina, Forente stater, 29601
    - Saint Francis Hospital
  - Greenville, South Carolina, Forente stater, 29605
    - Prisma Health Greenville Memorial Hospital
  - Greer, South Carolina, Forente stater, 29650
    - Prisma Health Cancer Institute - Greer
  - Greer, South Carolina, Forente stater, 29651
    - Gibbs Cancer Center-Pelham
  - Hilton Head Island, South Carolina, Forente stater, 29926-3827
    - South Carolina Cancer Specialists PC
  - Seneca, South Carolina, Forente stater, 29672
    - Prisma Health Cancer Institute - Seneca
  - Spartanburg, South Carolina, Forente stater, 29303
    - Spartanburg Medical Center
  - Union, South Carolina, Forente stater, 29379
    - MGC Hematology Oncology-Union
  - West Columbia, South Carolina, Forente stater, 29169
    - Lexington Medical Center
- South Dakota
  - Aberdeen, South Dakota, Forente stater, 57401
    - Avera Cancer Institute-Aberdeen
  - Sioux Falls, South Dakota, Forente stater, 57105
    - Avera Cancer Institute
  - Sioux Falls, South Dakota, Forente stater, 57117-5134
    - Sanford USD Medical Center - Sioux Falls
  - Sioux Falls, South Dakota, Forente stater, 57104
    - Sanford Cancer Center Oncology Clinic
  - Yankton, South Dakota, Forente stater, 57078
    - Avera Cancer Institute at Yankton
- Tennessee
  - Alcoa, Tennessee, Forente stater, 37701
    - University Cancer Specialists - Alcoa
  - Collierville, Tennessee, Forente stater, 38017
    - Baptist Memorial Hospital and Cancer Center-Collierville
  - Cookeville, Tennessee, Forente stater, 38501
    - Cookeville Regional Medical Center
  - Franklin, Tennessee, Forente stater, 37067
    - Vanderbilt-Ingram Cancer Center Cool Springs
  - Kingsport, Tennessee, Forente stater, 37660
    - Ballad Health Cancer Care - Kingsport
  - Knoxville, Tennessee, Forente stater, 37920
    - University of Tennessee - Knoxville
  - Memphis, Tennessee, Forente stater, 38120
    - Baptist Memorial Hospital and Cancer Center-Memphis
  - Nashville, Tennessee, Forente stater, 37232
    - Vanderbilt University/Ingram Cancer Center
  - Nashville, Tennessee, Forente stater, 37204
    - Vanderbilt Breast Center at One Hundred Oaks
- Texas
  - Amarillo, Texas, Forente stater, 79106
    - The Don and Sybil Harrington Cancer Center
  - Baytown, Texas, Forente stater, 77521
    - Houston Methodist San Jacinto Hospital
  - Bryan, Texas, Forente stater, 77802
    - Saint Joseph Regional Cancer Center
  - Conroe, Texas, Forente stater, 77384
    - MD Anderson in The Woodlands
  - Dallas, Texas, Forente stater, 75235
    - Parkland Memorial Hospital
  - Dallas, Texas, Forente stater, 75390
    - UT Southwestern/Simmons Cancer Center-Dallas
  - Dallas, Texas, Forente stater, 75237
    - UT Southwestern Simmons Cancer Center - RedBird
  - Fort Worth, Texas, Forente stater, 76104
    - UT Southwestern/Simmons Cancer Center-Fort Worth
  - Galveston, Texas, Forente stater, 77555-0565
    - University of Texas Medical Branch
  - Houston, Texas, Forente stater, 77030
    - M D Anderson Cancer Center
  - Houston, Texas, Forente stater, 77026-1967
    - Lyndon Baines Johnson General Hospital
  - Houston, Texas, Forente stater, 77030
    - Houston Methodist Hospital
  - Houston, Texas, Forente stater, 77030
    - Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
  - Houston, Texas, Forente stater, 77070
    - Methodist Willowbrook Hospital
  - Houston, Texas, Forente stater, 77030
    - Ben Taub General Hospital
  - Houston, Texas, Forente stater, 77094
    - Houston Methodist West Hospital
  - Houston, Texas, Forente stater, 77079
    - MD Anderson West Houston
  - Laredo, Texas, Forente stater, 78041
    - Doctor's Hospital of Laredo
  - League City, Texas, Forente stater, 77573
    - MD Anderson League City
  - Lubbock, Texas, Forente stater, 79415
    - UMC Cancer Center / UMC Health System
  - Nassau Bay, Texas, Forente stater, 77058
    - Houston Methodist Saint John Hospital
  - Richardson, Texas, Forente stater, 75080
    - UT Southwestern Clinical Center at Richardson/Plano
  - Sugar Land, Texas, Forente stater, 77478
    - MD Anderson in Sugar Land
  - Sugar Land, Texas, Forente stater, 77479
    - Houston Methodist Sugar Land Hospital
  - The Woodlands, Texas, Forente stater, 77385
    - Houston Methodist The Woodlands Hospital
- Virginia
  - Bristol, Virginia, Forente stater, 24201
    - Wellmont Medical Associates-Bristol
  - Burke, Virginia, Forente stater, 22015
    - Kaiser Permanente-Burke Medical Center
  - Chesapeake, Virginia, Forente stater, 23320
    - Cancer Specialists of Tidewater Limited
  - Fairfax, Virginia, Forente stater, 22031
    - Inova Schar Cancer Institute
  - Fairfax, Virginia, Forente stater, 22033
    - Inova Fair Oaks Hospital
  - Gloucester, Virginia, Forente stater, 23061
    - Peninsula Cancer Institute-Gloucester
  - Lynchburg, Virginia, Forente stater, 24501
    - Centra Alan B Pearson Regional Cancer Center
  - McLean, Virginia, Forente stater, 22102
    - Kaiser Permanente Tysons Corner Medical Center
  - Mechanicsville, Virginia, Forente stater, 23116
    - Bon Secours Memorial Regional Medical Center
  - Midlothian, Virginia, Forente stater, 23114
    - Bon Secours Saint Francis Medical Center
  - Midlothian, Virginia, Forente stater, 23113
    - Bon Secours Westchester Emergency Center
  - Newport News, Virginia, Forente stater, 23601
    - Peninsula Cancer Institute-Newport News
  - Norfolk, Virginia, Forente stater, 23505
    - Bon Secours DePaul Medical Center
  - Portsmouth, Virginia, Forente stater, 23707
    - Bon Secours Maryview Medical Center
  - Richmond, Virginia, Forente stater, 23235
    - VCU Massey Cancer Center at Stony Point
  - Richmond, Virginia, Forente stater, 23298
    - Virginia Commonwealth University/Massey Cancer Center
  - Richmond, Virginia, Forente stater, 23229
    - Virginia Cancer Institute
  - Richmond, Virginia, Forente stater, 23226
    - Bon Secours Saint Mary's Hospital
  - Richmond, Virginia, Forente stater, 23230
    - Bon Secours Cancer Institute at Reynolds Crossing
  - South Hill, Virginia, Forente stater, 23970
    - VCU Community Memorial Health Center
  - Suffolk, Virginia, Forente stater, 23435
    - Cancer Specialists of Tidewater-Suffolk
  - Suffolk, Virginia, Forente stater, 23435
    - Bon Secours Health Center at Harbour View
  - Virginia Beach, Virginia, Forente stater, 23454
    - Peninsula Cancer Institute-Cancer Specialists of Tidewater
  - Williamsburg, Virginia, Forente stater, 23185
    - Peninsula Cancer Institute-Williamsburg
  - Woodbridge, Virginia, Forente stater, 22192
    - Kaiser Permanente-Caton Hill Medical Center
- Washington
  - Aberdeen, Washington, Forente stater, 98520
    - Providence Regional Cancer System-Aberdeen
  - Auburn, Washington, Forente stater, 98001
    - MultiCare Auburn Medical Center
  - Bellevue, Washington, Forente stater, 98004
    - Overlake Medical Center
  - Bellingham, Washington, Forente stater, 98225
    - PeaceHealth Saint Joseph Medical Center
  - Bremerton, Washington, Forente stater, 98310
    - Harrison HealthPartners Hematology and Oncology-Bremerton
  - Burien, Washington, Forente stater, 98166
    - Highline Medical Center-Main Campus
  - Centralia, Washington, Forente stater, 98531
    - Providence Regional Cancer System-Centralia
  - Edmonds, Washington, Forente stater, 98026
    - Swedish Cancer Institute-Edmonds
  - Enumclaw, Washington, Forente stater, 98022
    - Saint Elizabeth Hospital
  - Everett, Washington, Forente stater, 98201
    - Providence Regional Cancer Partnership
  - Federal Way, Washington, Forente stater, 98003
    - Saint Francis Hospital
  - Gig Harbor, Washington, Forente stater, 98335
    - MultiCare Gig Harbor Medical Park
  - Issaquah, Washington, Forente stater, 98029
    - Swedish Cancer Institute-Issaquah
  - Kennewick, Washington, Forente stater, 99336
    - Kadlec Clinic Hematology and Oncology
  - Lacey, Washington, Forente stater, 98503
    - Providence Regional Cancer System-Lacey
  - Lakewood, Washington, Forente stater, 98499
    - Saint Clare Hospital
  - Longview, Washington, Forente stater, 98632
    - PeaceHealth Saint John Medical Center
  - Port Townsend, Washington, Forente stater, 98368
    - Jefferson Healthcare
  - Poulsbo, Washington, Forente stater, 98370
    - Harrison HealthPartners Hematology and Oncology-Poulsbo
  - Puyallup, Washington, Forente stater, 98372
    - MultiCare Good Samaritan Hospital
  - Renton, Washington, Forente stater, 98055
    - Valley Medical Center
  - Seattle, Washington, Forente stater, 98107
    - Swedish Medical Center-Ballard Campus
  - Seattle, Washington, Forente stater, 98122
    - Swedish Medical Center-First Hill
  - Seattle, Washington, Forente stater, 98104
    - Pacific Gynecology Specialists
  - Seattle, Washington, Forente stater, 98122-5711
    - Swedish Medical Center-Cherry Hill
  - Sedro-Woolley, Washington, Forente stater, 98284
    - PeaceHealth United General Medical Center
  - Shelton, Washington, Forente stater, 98584
    - Providence Regional Cancer System-Shelton
  - Silverdale, Washington, Forente stater, 98383
    - Saint Michael Cancer Center
  - Spokane, Washington, Forente stater, 99204
    - MultiCare Deaconess Cancer and Blood Specialty Center - Downtown
  - Spokane, Washington, Forente stater, 99218
    - MultiCare Deaconess Cancer and Blood Specialty Center - North
  - Tacoma, Washington, Forente stater, 98405
    - Northwest Medical Specialties PLLC
  - Tacoma, Washington, Forente stater, 98405
    - MultiCare Tacoma General Hospital
  - Tacoma, Washington, Forente stater, 98405
    - Franciscan Research Center-Northwest Medical Plaza
  - Vancouver, Washington, Forente stater, 98686
    - Legacy Salmon Creek Hospital
  - Vancouver, Washington, Forente stater, 98664
    - PeaceHealth Southwest Medical Center
  - Vancouver, Washington, Forente stater, 98684
    - Legacy Cancer Institute Medical Oncology and Day Treatment
  - Walla Walla, Washington, Forente stater, 99362
    - Providence Saint Mary Regional Cancer Center
  - Yakima, Washington, Forente stater, 98902
    - North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
  - Yelm, Washington, Forente stater, 98597
    - Providence Regional Cancer System-Yelm
- West Virginia
  - Charleston, West Virginia, Forente stater, 25304
    - West Virginia University Charleston Division
  - Huntington, West Virginia, Forente stater, 25701
    - Edwards Comprehensive Cancer Center
- Wisconsin
  - Antigo, Wisconsin, Forente stater, 54409
    - Langlade Hospital and Cancer Center
  - Appleton, Wisconsin, Forente stater, 54911
    - ThedaCare Regional Cancer Center
  - Appleton, Wisconsin, Forente stater, 54915
    - Ascension Saint Elizabeth Hospital
  - Ashland, Wisconsin, Forente stater, 54806
    - Duluth Clinic Ashland
  - Ashland, Wisconsin, Forente stater, 54806
    - Northwest Wisconsin Cancer Center
  - Brookfield, Wisconsin, Forente stater, 53045
    - Ascension Southeast Wisconsin Hospital - Elmbrook Campus
  - Burlington, Wisconsin, Forente stater, 53105
    - Aurora Cancer Care-Southern Lakes VLCC
  - Chilton, Wisconsin, Forente stater, 53014
    - Ascension Calumet Hospital
  - Cudahy, Wisconsin, Forente stater, 53110
    - Aurora Saint Luke's South Shore
  - Eau Claire, Wisconsin, Forente stater, 54701
    - Marshfield Medical Center-EC Cancer Center
  - Eau Claire, Wisconsin, Forente stater, 54701
    - HSHS Sacred Heart Hospital
  - Franklin, Wisconsin, Forente stater, 53132
    - Ascension Saint Francis - Reiman Cancer Center
  - Franklin, Wisconsin, Forente stater, 53132
    - Ascension Southeast Wisconsin Hospital - Franklin
  - Germantown, Wisconsin, Forente stater, 53022
    - Aurora Health Care Germantown Health Center
  - Grafton, Wisconsin, Forente stater, 53024
    - Aurora Cancer Care-Grafton
  - Green Bay, Wisconsin, Forente stater, 54311
    - Aurora BayCare Medical Center
  - Green Bay, Wisconsin, Forente stater, 54301
    - Saint Vincent Hospital Cancer Center Green Bay
  - Green Bay, Wisconsin, Forente stater, 54303
    - Saint Vincent Hospital Cancer Center at Saint Mary's
  - Janesville, Wisconsin, Forente stater, 53548
    - Mercyhealth Hospital and Cancer Center - Janesville
  - Johnson Creek, Wisconsin, Forente stater, 53038
    - University of Wisconsin Carbone Cancer Center - Johnson Creek
  - Kenosha, Wisconsin, Forente stater, 53142
    - Aurora Cancer Care-Kenosha South
  - La Crosse, Wisconsin, Forente stater, 54601
    - Gundersen Lutheran Medical Center
  - Madison, Wisconsin, Forente stater, 53792
    - University of Wisconsin Carbone Cancer Center - University Hospital
  - Marinette, Wisconsin, Forente stater, 54143
    - Aurora Bay Area Medical Group-Marinette
  - Marshfield, Wisconsin, Forente stater, 54449
    - Marshfield Medical Center-Marshfield
  - Medford, Wisconsin, Forente stater, 54451
    - Aspirus Medford Hospital
  - Menomonee Falls, Wisconsin, Forente stater, 53051
    - Froedtert Menomonee Falls Hospital
  - Mequon, Wisconsin, Forente stater, 53097
    - Ascension Columbia Saint Mary's Hospital Ozaukee
  - Milwaukee, Wisconsin, Forente stater, 53226
    - Medical College of Wisconsin
  - Milwaukee, Wisconsin, Forente stater, 53209
    - Aurora Cancer Care-Milwaukee
  - Milwaukee, Wisconsin, Forente stater, 53215
    - Aurora Saint Luke's Medical Center
  - Milwaukee, Wisconsin, Forente stater, 53233
    - Aurora Sinai Medical Center
  - Milwaukee, Wisconsin, Forente stater, 53210
    - Ascension Southeast Wisconsin Hospital - Saint Joseph Campus
  - Milwaukee, Wisconsin, Forente stater, 53211
    - Ascension Columbia Saint Mary's Hospital - Milwaukee
  - Milwaukee, Wisconsin, Forente stater, 53215
    - Ascension Saint Francis Hospital
  - Minocqua, Wisconsin, Forente stater, 54548
    - Marshfield Clinic-Minocqua Center
  - Mukwonago, Wisconsin, Forente stater, 53149
    - ProHealth D N Greenwald Center
  - Neenah, Wisconsin, Forente stater, 54956
    - ThedaCare Regional Medical Center - Neenah
  - New Richmond, Wisconsin, Forente stater, 54017
    - Cancer Center of Western Wisconsin
  - Oak Creek, Wisconsin, Forente stater, 53154
    - Drexel Town Square Health Center
  - Oconomowoc, Wisconsin, Forente stater, 53066
    - ProHealth Oconomowoc Memorial Hospital
  - Oconto Falls, Wisconsin, Forente stater, 54154
    - Saint Vincent Hospital Cancer Center at Oconto Falls
  - Oshkosh, Wisconsin, Forente stater, 54904
    - Ascension Mercy Hospital
  - Oshkosh, Wisconsin, Forente stater, 54904
    - Vince Lombardi Cancer Clinic - Oshkosh
  - Racine, Wisconsin, Forente stater, 53406
    - Aurora Cancer Care-Racine
  - Racine, Wisconsin, Forente stater, 53405
    - Ascension All Saints Hospital
  - Rhinelander, Wisconsin, Forente stater, 54501
    - Ascension Saint Mary's Hospital
  - Rice Lake, Wisconsin, Forente stater, 54868
    - Marshfield Medical Center-Rice Lake
  - Sheboygan, Wisconsin, Forente stater, 53081
    - Vince Lombardi Cancer Clinic-Sheboygan
  - Stevens Point, Wisconsin, Forente stater, 54481
    - Ascension Saint Michael's Hospital
  - Stevens Point, Wisconsin, Forente stater, 54482
    - Marshfield Medical Center-River Region at Stevens Point
  - Sturgeon Bay, Wisconsin, Forente stater, 54235-1495
    - Saint Vincent Hospital Cancer Center at Sturgeon Bay
  - Summit, Wisconsin, Forente stater, 53066
    - Aurora Medical Center in Summit
  - Two Rivers, Wisconsin, Forente stater, 54241
    - Vince Lombardi Cancer Clinic-Two Rivers
  - Waukesha, Wisconsin, Forente stater, 53188
    - UW Cancer Center at ProHealth Care
  - Waukesha, Wisconsin, Forente stater, 53188
    - ProHealth Waukesha Memorial Hospital
  - Waupaca, Wisconsin, Forente stater, 54981
    - ThedaCare Cancer Care - Waupaca
  - Wausau, Wisconsin, Forente stater, 54401
    - Aspirus Regional Cancer Center
  - Wauwatosa, Wisconsin, Forente stater, 53226
    - Aurora Cancer Care-Milwaukee West
  - Wauwatosa, Wisconsin, Forente stater, 53226
    - Ascension Medical Group Southeast Wisconsin - Mayfair Road
  - West Allis, Wisconsin, Forente stater, 53227
    - Aurora West Allis Medical Center
  - West Bend, Wisconsin, Forente stater, 53095
    - Froedtert West Bend Hospital/Kraemer Cancer Center
  - Weston, Wisconsin, Forente stater, 54476
    - Marshfield Medical Center - Weston
  - Wisconsin Rapids, Wisconsin, Forente stater, 54494
    - Aspirus Cancer Care - Wisconsin Rapids
- Wyoming
  - Cheyenne, Wyoming, Forente stater, 82001
    - Cheyenne Regional Medical Center-West
  - Cody, Wyoming, Forente stater, 82414
    - Billings Clinic-Cody
  - Sheridan, Wyoming, Forente stater, 82801
    - Welch Cancer Center
Puerto Rico
- - Bayamón, Puerto Rico, 00959-5060
    - Cancer Center-Metro Medical Center Bayamon
  - Bayamón, Puerto Rico, 00961
    - Puerto Rico Hematology Oncology Group
  - Manati, Puerto Rico, 00674
    - Doctors Cancer Center
  - San Juan, Puerto Rico, 00917
    - San Juan Community Oncology Group
  - San Juan, Puerto Rico, 00927
    - Centro Comprensivo de Cancer de UPR
  - San Juan, Puerto Rico, 00936
    - San Juan City Hospital
  - San Juan, Puerto Rico, 00927
    - PROncology

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

18 år og eldre (Voksen, Eldre voksen)

Tar imot friske frivillige

Nei

Beskrivelse

Inklusjonskriterier:

HER2-positiv status vil være basert på forbehandlingsbiopsimateriale og definert som en immunhistokjemi (IHC) score på 3+ og/eller positiv ved in situ hybridisering (ISH) i henhold til gjeldende American Society of Clinical Oncology (ASCO) College of American Pathologists ( CAP) retningslinjer. Sentral testing er ikke nødvendig
* Kjent hormonreseptor (HR) status som definert av ASCO/CAP-retningslinjer (basert på biopsimateriale før behandling). Hormonreseptor positiv status kan bestemmes av enten kjent positiv østrogenreseptor (ER) eller kjent positiv progesteronreseptor (PR) status; hormonreseptor negativ status må bestemmes av både kjent negativ ER og kjent negativ PR
Pasienter med klinisk stadium T1-4, N0-3 sykdom ved presentasjon og gjenværende invasiv sykdom postoperativt som definert ovenfor er kvalifisert. (Merk: Pasienter med T1a/bN0-svulster er ikke kvalifisert ved første diagnose av brystkreft er ikke kvalifisert)
Pasienter med gjenværende HR-negativ, HER2 positiv (+) sykdom i bryst og/eller lymfeknuter i henhold til kirurgisk patologirapport er kvalifisert; Pasienter med HR+ HER2+-kreft må imidlertid ha nodepositiv restsykdom i henhold til den kirurgiske patologirapporten for å kvalifisere for studien. Tilstedeværelsen av gjenværende invasiv sykdom i brystet er ikke obligatorisk for disse pasientene
Pasienter med svakt ER-positiv (1-10 %) brystkreft (basert på kjernebiopsien for forbehandling) er kvalifisert selv om de har node-negativ sykdom i henhold til kirurgisk patologirapport
Det gjenværende sykdomsvevet (bryst- og/eller lymfeknuter) er ikke nødvendig å være HER2-positivt, da kvalifisering for NCI-2020-03770 (A011801) er basert på en positiv HER2-status på tidspunktet for den første brystkreftdiagnosen
* Merk: Tilstedeværelsen av mikrometastaser i lymfeknuter etter preoperativ terapi teller som gjenværende sykdom, mens tilstedeværelsen av isolerte tumorceller ikke
Pasienter med synkron bilateral invasiv sykdom er kvalifisert forutsatt at begge lesjonene ble bekreftet å være HER2-positive, og minst én av lesjonene oppfyller kriteriene skissert ovenfor. Multifokal sykdom er tillatt, så lenge den største biopsierte brystsvulsten var HER2-positiv
Pasienter må ha fått neoadjuvant kjemoterapi med ett av følgende regimer: docetaksel/trastuzumab/pertuzumab (THP), paklitaksel/metotreksat/cisplatin (TMP), doksorubicin/cyklofosfamid/paklitaksel/trastuzumab/pertuzumab (AC-TH(P)); docetaxel/karboplatin/trastuzumab/pertuzumab (TCH(P)); fluorouracil/doksorubicin/cyklofosfamid-docetaksel/trastuzumab/pertuzumab (FAC-TH(P)), eller fluorouracil/epirubicin/cyklofosfamid-docetaksel/trastuzumab/pertuzumab (FEC-TH(P)). Merk: bortsett fra TCHP, der T er docetaxel, er behandling med docetaxel eller paklitaksel akseptabelt
Forhåndsmottak av T-DM1 i neoadjuvant setting er ikke tillatt.
- Tidligere behandling må ha bestått av >= 6 sykluser med kjemoterapi og HER2-rettet terapi, med en total varighet på >= 12 uker, inkludert minst 9 uker med preoperativ taxan og trastuzumab med eller uten pertuzumab (eller Food and Drug Administration [FDA] ]-godkjente biosimilarer). Pasienter som har mottatt minst 9 uker preoperativ taxan, pertuzumab og margetuximab er også kvalifisert dersom de mottok >= 6 sykluser med systemisk terapi før innrullering. Merk: Pasienter som fullfører minst ni av planlagte tolv doser ukentlig paklitaksel, eller tre av planlagte fire doser docetaksel, men som avslutter behandlingen for tidlig på grunn av toksisitet, er kvalifisert. Pasienter som får dosetette kjemoterapiregimer er også kvalifisert. Tidligere bruk av nab-paklitaksel (Abraxane) i stedet for paklitaksel eller docetaksel er tillatt. Tidligere bruk av subkutan trastuzumab (Hylecta) og subkutan trastuzumab og pertuzumab (Phesgo) er også tillatt.
- Pasienter som fikk neoadjuvant systemisk terapi som inkluderte eksperimentell HER2-målrettet terapi/terapier er potensielt kvalifiserte, så lenge undersøkelsesmidlet ikke var et HER2-målrettet antistoff-legemiddelkonjugat (f.eks. T-DM1, DS-8201a [trastuzumab deruxtecan]) eller en HER2-målrettet tyrosinkinaseinhibitor (TKI) (f.eks. tucatinib, lapatinib, neratinib).
Pasienter kan ha mottatt =< 1 sykluser med T-DM1 i adjuvant setting. Merk: Disse pasientene vil bli randomisert til å motta ytterligere 14 sykluser med T-DM1 og tucatinib/placebo som tolerert. Den siste syklusen av T-DM1 skal ha blitt administrert =< 5 uker før registrering
* Merk: Begge de to følgende kriteriene må oppfylles for at pasienten skal være kvalifisert for denne studien
- Et intervall på ikke mer enn 12 uker mellom sluttdatoen for den siste definitive behandlingen (f. postoperativ kjemoterapi eller stråling, eller hvis ingen av disse er gitt, dato for brystkirurgi) og registreringsdato. Samtidig strålebehandling er tillatt under studiebehandling
- Pasienter må registreres på studien innen =< 180 dager etter datoen for den siste definitive brystkreftoperasjonen (ikke inkludert rekonstruktiv kirurgi)
All systemisk kjemoterapi burde vært fullført preoperativt med mindre du har deltatt i EA1181 (CompassHER2 patologisk fullstendig respons [pCR]) eller BIG DECRESCENDO Trial (som er svært lik CompassHER2 pCR når det gjelder studiedesign, medikamenter og kvalifisering). Imidlertid kan pasienter som mottok 4 sykluser med neoadjuvant THP off-studie motta ytterligere 2-4 sykluser med kjemoterapi postoperativt for å oppfylle kvalifikasjonen for A011801. Pasienter som deltok i EA1181 eller MA41 og fortsatte til kirurgi umiddelbart etter det deeskalerte prøveregimet, må motta postoperativ kjemoterapi for å fullføre totalt >= 6 sykluser med systemisk behandling før registrering på A011801, som skissert ovenfor (f.eks. 4 sykluser før- operativt og 2 sykluser postoperativt). Det postoperative kjemoterapiregimet som er foreskrevet er etter den behandlende onkologen (dvs. 2-4 sykluser AC eller THP, annet). Fortsettelse av trastuzumab + pertuzumab (HP) pre- eller postoperativt som vedlikeholdsbehandling (i påvente av en kirurgisk dato eller en offisiell patologirapport) er tillatt for alle studiedeltakere
Toksisiteter relatert til tidligere systemisk behandling bør ha forsvunnet eller være ved baseline, bortsett fra alopecia og perifer nevropati =< grad 1
Tilstrekkelig eksisjon: kirurgisk fjerning av all klinisk tydelig sykdom i bryst og lymfeknuter som følger:
- Brystkirurgi: total mastektomi uten grov gjenværende sykdom ved reseksjonsmarginen, eller brystbevarende operasjon med histologisk negative utskjæringsmarginer
- For pasienter som gjennomgår brystbevarende kirurgi, må marginene til den resekerte prøven være histologisk fri for invasiv tumor og ductal carcinoma in situ (DCIS) som bestemt av den lokale patologen. Hvis patologisk undersøkelse viser tumor ved reseksjonslinjen, kan ytterligere operative prosedyrer utføres for å oppnå klare marginer. Hvis svulsten fortsatt er tilstede ved den resekerte marginen etter re-eksisjon(er), må pasienten gjennomgå total mastektomi for å være kvalifisert. Pasienter med marginer positive for klassisk lobulært karsinom in situ (LCIS) er kvalifisert uten ytterligere reseksjon
- Lymfeknutekirurgi ** Aksillen må evalueres med enten vaktpostbiopsi eller aksillær lymfeknutedisseksjon. Hvis pasienter har en vaktpostlymfeknutebiopsi og vaktpostknuter er negative, er det ikke nødvendig med ytterligere aksillær behandling. Hvis pasienter har isolerte tumorceller (ITC) i sammenheng med gjenværende brystsykdom, kreves minst ett av følgende: aksillær lymfeknutedisseksjon (ALND) eller planlagt nodal bestråling. Hvis pasienter har mikro- eller makrometastatisk nodalsykdom, er ALND og planlagt nodalbestråling nødvendig. Merk at medregistrering på Alliance A011202 ikke er tillatt
Eastern Cooperative Oncology Group (ECOG) ytelsesstatus 0-1
Absolutt nøytrofiltall (ANC) >= 1000/mm^3
Hemoglobin >= 8 g/dL (Merk: pakkede røde blodlegemer [PRBC] transfusjon er ikke tillatt for å oppnå kvalifisering)
Blodplateantall >= 100 000/mm^3
Kreatinin =< 1,5 x øvre normalgrense (ULN)
Total bilirubin =< 1,0 x øvre normalgrense (ULN) eller direkte bilirubin innenfor det institusjonelle normalområdet for pasienter med Gilberts syndrom
Aspartataminotransferase (AST)/alaninaminotransferase (ALT) =< 2,5 x øvre normalgrense (ULN)
Screening av venstre ventrikkel ejeksjonsfraksjon (LVEF) >= 50 % på ekkokardiogram (ECHO) eller multiple-gated acquisition (MUGA) etter å ha mottatt neoadjuvant kjemoterapi og ingen reduksjon i LVEF med mer enn 15 % absolutte prosentpoeng fra LVEF før kjemoterapi. Eller, hvis pre-kjemoterapi LVEF ikke ble vurdert, må screening LVEF være >= 55 % etter fullført neoadjuvant kjemoterapi. Merk: LVEF-vurdering kan gjentas én gang i opptil 3 uker etter den første screeningsvurderingen for å vurdere kvalifisering

Ekskluderingskriterier:

Ingen adjuvant behandling med noen kreftmedisiner innen 28 dager før registrering
Ikke gravid og ikke ammende, fordi denne studien involverer et middel som har kjente genotoksiske, mutagene og teratogene effekter. Derfor, kun for kvinner i fertil alder, kreves en negativ serumgraviditetstest =< 7 dager før registrering.
Pasienter med kjent aktiv og/eller ubehandlet hepatitt B eller hepatitt C eller kronisk leversykdom er ikke kvalifisert. Pasienter med en diagnose av hepatitt B eller C som er behandlet og ryddet og normal leverfunksjon er kvalifisert til å delta i studien hvis de andre kvalifikasjonsparametrene er oppfylt
Stadium IV (metastatisk) brystkreft
Anamnese med tidligere (ipsi- eller kontralateral) invasiv brystkreft innen 3 år etter registrering
Pasienter med ER+ HER2+ gjenværende invasiv sykdom som er lymfeknute-negativ i henhold til den kirurgiske patologirapporten
Bevis på tilbakevendende sykdom etter preoperativ terapi og kirurgi
Pasienter som strålebehandling vil bli anbefalt for behandling av brystkreft, men som det er kontraindisert for på grunn av medisinske årsaker (f.eks. bindevevsforstyrrelser eller tidligere ipsilateral bryststråling)
Anamnese med eksponering for følgende kumulative doser av antracykliner: doksorubicin > 240 mg/m^2; epirubicin eller liposomalt doksorubicin-hydroklorid (Myocet) > 480 mg/m^2. For andre antracykliner, eksponering tilsvarende doksorubicin > 240 mg/m^2
Kardiopulmonal dysfunksjon som definert av ett av følgende:
- Historie om National Cancer Institute (NCI) CTCAE versjon (v) 5.0 grad >= 3 symptomatisk kongestiv hjertesvikt (CHF) eller New York Heart Association (NYHA) kriterieklasse >= II
- Angina pectoris som krever anti-anginal medisin, alvorlig hjertearytmi som ikke kontrolleres av tilstrekkelig medisin, alvorlig ledningsavvik eller klinisk signifikant klaffesykdom
- Ukontrollerte arytmier med høy risiko: det vil si atrietakykardi med hjertefrekvens > 100/min i hvile, signifikant ventrikulær arytmi (ventrikulær takykardi) eller høyere grad av atrioventrikulær blokk (AV)-blokk (annen grads AV-blokk type 2 [Mobitz 2 ] eller tredje grads AV-blokk)
- Signifikante symptomer (grad >= 2) relatert til venstre ventrikkel dysfunksjon, hjertearytmi eller hjerteiskemi mens eller etter at du har mottatt preoperativ behandling
- Anamnese med en reduksjon i venstre ventrikkel ejeksjonsfraksjon (LVEF) til < 40 % med tidligere trastuzumab-behandling (f.eks. under preoperativ behandling)
- Ukontrollert hypertensjon (systolisk blodtrykk > 180 mmHg og/eller diastolisk blodtrykk > 100 mmHg)
Nåværende alvorlig, ukontrollert systemisk sykdom
Større kirurgisk prosedyre som ikke er relatert til brystkreft eller betydelig traumatisk skade innen 28 dager før registrering eller påvente av behovet for større kirurgi i løpet av studiebehandlingen
Anamnese med intoleranse, inkludert grad 3 til 4 infusjonsreaksjoner eller overfølsomhet overfor trastuzumab eller murine proteiner eller noen komponenter i produktet
Perifer nevropati av enhver etiologi som overstiger grad 1
Vurdering fra etterforskeren som ikke i stand til eller uvillig til å overholde kravene i protokollen
Bruk av en sterk CYP3A4- eller CYP2C8-hemmer innen 2 uker, eller bruk av en sterk CYP3A4- eller CYP2C8-induktor innen 5 dager før registrering er forbudt.
- Vær oppmerksom på at bruk av sensitive CYP3A-substrater bør unngås to uker før registrering og under studiebehandling. I tillegg er CYP3A4- eller CYP2C8-induktorer forbudt som samtidig medisinering innen 5 dager etter seponering av tucatinib-behandling. Pasienter som trenger medisiner som er kjent for å være sensitive substrater for CYP3A4 med et smalt terapeutisk vindu, bør ekskluderes.

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

Primært formål: Behandling
Tildeling: Randomisert
Intervensjonsmodell: Parallell tildeling
Masking: Dobbelt

Antall våpen

Våpen og intervensjoner

Deltakergruppe / Arm	Intervensjon / Behandling
Aktiv komparator: Arm I (trastuzumab emtansine, placebo) Patients receive T-DM1 IV over 30-90 minutes on day 1 and placebo PO BID on days 1-21. Treatment repeats every 21 days for up to 14 cycles in the absence of disease progression or unacceptable toxicity. Patients undergo echocardiography/multigated acquisition (MUGA) scan and blood sample collection throughout the study. Patients undergo echocardiography/multigated acquisition (MUGA) scan and blood sample collection throughout the study.	Annen: Livskvalitetsvurdering Hjelpestudier Annen: Spørreskjemaadministrasjon Hjelpestudier Biologisk: Trastuzumab Emtansine Gitt IV Legemiddel: Placebo administrasjon Gitt PO
Eksperimentell: Arm II (trastuzumab emtansine, tucatinib) Patients receive T-DM1 IV over 30-90 minutes on day 1 and tucatinib PO BID on days 1-21. Treatment repeats every 21 days for up to 14 cycles in the absence of disease progression or unacceptable toxicity. Patients undergo echocardiography/multigated acquisition (MUGA) scan and blood sample collection throughout the study.	Annen: Livskvalitetsvurdering Hjelpestudier Annen: Spørreskjemaadministrasjon Hjelpestudier Biologisk: Trastuzumab Emtansine Gitt IV Legemiddel: Tucatinib Gitt PO

Deltakergruppe / Arm

Intervensjon / Behandling

Aktiv komparator: Arm I (trastuzumab emtansine, placebo)

Patients receive T-DM1 IV over 30-90 minutes on day 1 and placebo PO BID on days 1-21. Treatment repeats every 21 days for up to 14 cycles in the absence of disease progression or unacceptable toxicity. Patients undergo echocardiography/multigated acquisition (MUGA) scan and blood sample collection throughout the study. Patients undergo echocardiography/multigated acquisition (MUGA) scan and blood sample collection throughout the study.

Annen: Livskvalitetsvurdering

Hjelpestudier

Annen: Spørreskjemaadministrasjon

Hjelpestudier

Biologisk: Trastuzumab Emtansine

Gitt IV

Legemiddel: Placebo administrasjon

Gitt PO

Eksperimentell: Arm II (trastuzumab emtansine, tucatinib)

Patients receive T-DM1 IV over 30-90 minutes on day 1 and tucatinib PO BID on days 1-21. Treatment repeats every 21 days for up to 14 cycles in the absence of disease progression or unacceptable toxicity. Patients undergo echocardiography/multigated acquisition (MUGA) scan and blood sample collection throughout the study.

Annen: Livskvalitetsvurdering

Hjelpestudier

Annen: Spørreskjemaadministrasjon

Hjelpestudier

Biologisk: Trastuzumab Emtansine

Gitt IV

Legemiddel: Tucatinib

Gitt PO

Hva måler studien?

Primære resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
Modifisert invasiv sykdomsfri overlevelse (iDFS) Tidsramme: Fra randomisering til en av følgende hendelser: invasiv lokal, regional eller fjern tilbakefall, invasiv kontralateral brystkreft eller død av en hvilken som helst årsak, vurdert opp til 10 år	En Kaplan-Meier metode vil bli brukt for å estimere overlevelseskurvene og en stratifisert log-rank test vil bli brukt for å sammenligne den invasive sykdomsfrie overlevelsen (iDFS) til de to armene. En stratifisert Cox-modell vil bli brukt for å estimere fareforholdet. Hvis det ser ut til å være klinisk signifikante ubalanser av baselinevariabler mellom behandlingsarmene, vil en sekundær analyse av det primære endepunktet bruke stratifisert Cox-modell for å sammenligne behandlingseffektene som inkluderer variablene som anses som ubalanserte mellom armene som justerende variabler. Randomiseringsstratifiseringsvariablene vil være de stratifiserte variablene i modellen.	Fra randomisering til en av følgende hendelser: invasiv lokal, regional eller fjern tilbakefall, invasiv kontralateral brystkreft eller død av en hvilken som helst årsak, vurdert opp til 10 år

Sekundære resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
Umodifisert invasiv sykdomsfri overlevelse (iDFS) Tidsramme: Inntil 10 år	Vil bli definert som tiden fra randomisering til en av følgende hendelser: invasiv lokal, regional eller fjern residiv, invasiv kontralateral brystkreft sekundær primær invasiv kreft (annet enn basal- eller plateepitelkarsinom i huden, eller karsinom in situ i livmorhalsen ), eller død av en hvilken som helst årsak, vurdert opp til 10 år. En Kaplan-Meier metode vil bli brukt for å estimere overlevelseskurvene og en stratifisert log-rank test vil bli brukt for å sammenligne iDFS for de to armene. En stratifisert Cox-modell vil bli brukt for å estimere fareforholdet.	Inntil 10 år
Brystkreftfri overlevelse Tidsramme: Fra randomisering til invasiv lokal, regional eller fjern residiv, eller invasiv kontralateral brystkreft, vurdert opp til 10 år	Vil oppsummeres med Kaplan-Meier kurver og sammenlignes mellom armene ved bruk av en stratifisert log-rank test og stratifisert Cox modell. Hvis det er klinisk signifikante ubalanser i baseline-karakteristikker mellom behandlingsarmene, vil en andre analyse bli gjort ved bruk av en stratifisert Cox-modell med variablene som er ubalanse lagt til som justerende variabler.	Fra randomisering til invasiv lokal, regional eller fjern residiv, eller invasiv kontralateral brystkreft, vurdert opp til 10 år
Hjernemetastasefri overlevelse Tidsramme: Fra randomisering til dokumentasjon av involvering av sentralnervesystemet ved metastatisk kreft inkludert parenkymale hjerne- og ryggmargsmetastaser samt leptomeningeal karsinomatose, vurdert opp til 10 år	Vil oppsummeres med Kaplan-Meier kurver og sammenlignes mellom armene ved bruk av en stratifisert log-rank test og stratifisert Cox modell. Hvis det er klinisk signifikante ubalanser i baseline-karakteristikker mellom behandlingsarmene, vil en andre analyse bli gjort ved bruk av en stratifisert Cox-modell med variablene som er ubalanse lagt til som justerende variabler.	Fra randomisering til dokumentasjon av involvering av sentralnervesystemet ved metastatisk kreft inkludert parenkymale hjerne- og ryggmargsmetastaser samt leptomeningeal karsinomatose, vurdert opp til 10 år
Total overlevelse Tidsramme: Fra randomisering til død uansett årsak, vurdert opp til 10 år	Vil oppsummeres med Kaplan-Meier kurver og sammenlignes mellom armene ved bruk av en stratifisert log-rank test og stratifisert Cox modell. Hvis det er klinisk signifikante ubalanser i baseline-karakteristikker mellom behandlingsarmene, vil en andre analyse bli gjort ved bruk av en stratifisert Cox-modell med variablene som er ubalanse lagt til som justerende variabler.	Fra randomisering til død uansett årsak, vurdert opp til 10 år
Forekomst av hjernemetastaser Tidsramme: Inntil 10 år	En hendelse av hjernemetastaser er dokumentasjon på involvering av sentralnervesystemet ved metastatisk kreft, inkludert parenkymale hjerne- og ryggmargsmetastaser samt leptomeningeal karsinomatose. Den kumulative forekomsten av hjernemetastaser vil bli bestemt som den grove kumulative forekomsten så vel som med forekomsten med konkurrerende risiko der den konkurrerende begivenheten er død.	Inntil 10 år
Distant recurrence-free survival Tidsramme: From randomization to the first incidence of distant recurrence, assessed up to 10 years	Will be summarized with Kaplan-Meier curves and compared between the arms using a stratified log-rank test and stratified Cox model. If there are clinically significant imbalances in baseline characteristics between the treatment arms, a second analysis will be done using a stratified Cox model with the variables that are imbalanced added as adjusting variables.	From randomization to the first incidence of distant recurrence, assessed up to 10 years
Disease-free survival Tidsramme: From randomization to the first incidence of invasive local, regional, or distant recurrence, second primary non-breast cancer event, or contralateral or ipsilateral ductal carcinoma in situ, assessed up to 10 years.	Will be summarized with Kaplan-Meier curves and compared between the arms using a stratified log-rank test and stratified Cox model. If there are clinically significant imbalances in baseline characteristics between the treatment arms, a second analysis will be done using a stratified Cox model with the variables that are imbalance added as adjusting variables.	From randomization to the first incidence of invasive local, regional, or distant recurrence, second primary non-breast cancer event, or contralateral or ipsilateral ductal carcinoma in situ, assessed up to 10 years.

Andre resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
Quality of life Tidsramme: Up to day 1 of cycle 14 (each cycle is 21 days)	Will be assessed by the FACT-B Trial Outcome Index questionnaire. The mixed model will compare the mean change from baseline at cycle 14 day 1 between arms. If the two-sided 95% confidence interval excludes a difference of 5 favoring the T-DM1 + placebo arm, then non-inferiority will be concluded at this time point.	Up to day 1 of cycle 14 (each cycle is 21 days)

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

Alliance for Clinical Trials in Oncology

Samarbeidspartnere

National Cancer Institute (NCI)

Seagen Inc.

Etterforskere

Studiestol: Ciara C. O'Sullivan, MB, BCh, BAO, Mayo Clinic

Publikasjoner og nyttige lenker

Den som er ansvarlig for å legge inn informasjon om studien leverer frivillig disse publikasjonene. Disse kan handle om alt relatert til studiet.

Generelle publikasjoner

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart (Faktiske)

2. mars 2021

Primær fullføring (Antatt)

31. januar 2028

Studiet fullført (Antatt)

31. mai 2035

Datoer for studieregistrering

Først innsendt

30. juni 2020

Først innsendt som oppfylte QC-kriteriene

30. juni 2020

Først lagt ut (Faktiske)

7. juli 2020

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

15. juni 2026

Siste oppdatering sendt inn som oppfylte QC-kriteriene

11. juni 2026

Sist bekreftet

1. oktober 2025

Mer informasjon

Begreper knyttet til denne studien

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

A011801
U10CA180821 (U.S. NIH-stipend/kontrakt)
NCI-2020-03770 (Registeridentifikator: NCI Clinical Trial Reporting Program)

Plan for individuelle deltakerdata (IPD)

Planlegger du å dele individuelle deltakerdata (IPD)?

Legemiddel- og utstyrsinformasjon, studiedokumenter

Studerer et amerikansk FDA-regulert medikamentprodukt

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Nei

produkt produsert i og eksportert fra USA

Nei

Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .

T-DM1 og Tucatinib sammenlignet med T-DM1 alene for å forhindre tilbakefall hos personer med høyrisiko HER2-positiv brystkreft, CompassHER2 RD-prøven

CompassHER2-studiene (omfattende bruk av patologisk responsvurdering for å optimalisere terapi ved HER2-positiv brystkreft) CompassHER2 Residual Disease (RD), en dobbeltblindet, fase III randomisert studie av T-DM1 sammenlignet med T-DM1 og Tucatinib

Studieoversikt

Status

Forhold

Intervensjon / Behandling

Detaljert beskrivelse

Studietype

Registrering (Faktiske)

Fase

Kontakter og plasseringer

Studiesteder

Deltakelseskriterier

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

Tar imot friske frivillige

Beskrivelse

Studieplan

Hvordan er studiet utformet?

Designdetaljer

Antall våpen

Våpen og intervensjoner

Deltakergruppe / Arm

Intervensjon / Behandling

Hva måler studien?

Primære resultatmål

Resultatmål

Tiltaksbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Tiltaksbeskrivelse

Tidsramme

Andre resultatmål

Resultatmål

Tiltaksbeskrivelse

Tidsramme

Samarbeidspartnere og etterforskere

Sponsor

Samarbeidspartnere

Etterforskere

Publikasjoner og nyttige lenker

Generelle publikasjoner

Studierekorddatoer

Studer hoveddatoer

Studiestart (Faktiske)

Primær fullføring (Antatt)

Studiet fullført (Antatt)

Datoer for studieregistrering

Først innsendt

Først innsendt som oppfylte QC-kriteriene

Først lagt ut (Faktiske)

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

Siste oppdatering sendt inn som oppfylte QC-kriteriene

Sist bekreftet

Mer informasjon

Begreper knyttet til denne studien

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

Plan for individuelle deltakerdata (IPD)

Planlegger du å dele individuelle deltakerdata (IPD)?

Legemiddel- og utstyrsinformasjon, studiedokumenter

Studerer et amerikansk FDA-regulert medikamentprodukt

Studerer et amerikansk FDA-regulert enhetsprodukt

produkt produsert i og eksportert fra USA