Uric Acid to Albumin Ratio for Predicting Contrast Associated Acute Kidney Injury After Cardiac and Non Cardiac Procedures

Adult patients admitted to or evaluated at the Internal Medicine Department and related catheterization and interventional units at Assiut University Hospital who are scheduled to undergo cardiac (percutaneous coronary intervention) or non-cardiac diagnostic and interventional procedures requiring exposure to iodinated contrast media.

Inclusion Criteria:

• Adult patients aged 18 years or older undergoing a cardiac or non-cardiac procedure requiring iodinated contrast media.
• Cardiac group: patients undergoing percutaneous coronary intervention (PCI).
• Non-cardiac group: patients undergoing other diagnostic or interventional contrast procedures.
• Provision of written informed consent prior to enrollment.
• Available baseline (pre-procedural) serum creatinine, uric acid, and albumin measurements.

Exclusion Criteria:

• Severe chronic kidney disease or end-stage renal disease on regular maintenance hemodialysis (baseline eGFR < 15 mL/min/1.73 m^2).
• Exposure to iodinated contrast media within the preceding 7 to 10 days.
• Acute kidney injury from any cause present at admission or prior to contrast exposure.
• Active infection, sepsis, or systemic inflammatory response syndrome at the time of enrollment.
• Known history of gout, current use of urate-lowering therapy, or hematologic malignancy affecting uric acid metabolism.
• Severe hepatic disease or marked proteinuria affecting serum albumin independently of the study condition.
• Emergent PCI where baseline laboratory samples could not be obtained prior to contrast exposure.
• Patient death occurring before the 48 to 72 hour post-procedural serum creatinine evaluation could be performed.
• Pregnancy.
• Refusal of informed consent or loss to follow-up prior to outcome assessment.