Plyometrics for Strength and Function After Pediatric Burns
10 de maio de 2026 atualizado por: Maged Basha, Qassim University
Rebuilding Capacity With Plyometrics: A Novel and Potent Stimulus for Strength and Power, and Functional Performance in Pediatric Post-Burn Population
Pediatric burn survivors may experience persistent deficits in lower-limb strength, explosive power, and functional performance after hospital discharge.
This randomized controlled trial evaluated whether a 12-week supervised plyometric training program improves lower-extremity muscle strength, power, and functional capacity compared with a standard exercise program in children and adolescents with severe burn injuries.
Visão geral do estudo
Status
Concluído
Condições
Intervenção / Tratamento
Descrição detalhada
This two-arm, parallel-group, single-blind randomized controlled trial included 62 pediatric burn survivors aged 10-18 years with severe burns involving ≥30% total body surface area and lower-limb involvement. Participants were recruited 6-12 months after hospital discharge and randomly allocated in a 1:1 ratio to either plyometric training or standard exercise.
Both groups received supervised exercise twice weekly for 12 weeks. The experimental group completed progressive plyometric exercises designed to enhance lower-extremity explosive power and dynamic functional mobility. The control group received standard post-discharge rehabilitation focused on flexibility, aerobic conditioning, mobility, and basic strengthening. Outcomes were assessed at baseline and immediately after the 12-week intervention by blinded assessors.
Tipo de estudo
Intervencional
Inscrição (Real)
62
Estágio
- Não aplicável
Contactos e Locais
Esta seção fornece os detalhes de contato para aqueles que conduzem o estudo e informações sobre onde este estudo está sendo realizado.
Locais de estudo
-
-
-
Al Kharj, Arábia Saudita
- Prince Sattam Bin Abdulaziz University
-
-
Critérios de participação
Os pesquisadores procuram pessoas que se encaixem em uma determinada descrição, chamada de critérios de elegibilidade. Alguns exemplos desses critérios são a condição geral de saúde de uma pessoa ou tratamentos anteriores.
Critérios de elegibilidade
Idades elegíveis para estudo
- Filho
- Adulto
Aceita Voluntários Saudáveis
Não
Descrição
Inclusion Criteria:
- Children and adolescents aged 10-18 years at the time of enrolment.
- History of severe burn injury involving ≥30% total body surface area (TBSA), with lower-extremity involvement.
- Between 6 and 12 months post-hospital discharge.
- Ability to understand study instructions and safely perform the prescribed exercise program.
Exclusion Criteria:
- Pre-existing neurological or musculoskeletal disorders that may affect lower-limb function or study outcomes.
- Severe lower-limb joint contracture limiting functional movement.
- Cognitive impairment preventing understanding of instructions or reliable participation.
- Participation in another structured exercise, rehabilitation, or physical therapy program outside the study protocol during the trial period.
Plano de estudo
Esta seção fornece detalhes do plano de estudo, incluindo como o estudo é projetado e o que o estudo está medindo.
Como o estudo é projetado?
Detalhes do projeto
- Finalidade Principal: Tratamento
- Alocação: Randomizado
- Modelo Intervencional: Atribuição Paralela
- Mascaramento: Solteiro
Armas e Intervenções
Grupo de Participantes / Braço |
Intervenção / Tratamento |
|---|---|
|
Experimental: Plyometric Training Group
Participants received a 12-week supervised plyometric training program, twice weekly, with each session lasting 45 minutes.
Sessions included dynamic warm-up, progressive plyometric exercises targeting vertical and horizontal force production, and cool-down.
|
Participants in the plyometric training group will receive a 12-week supervised program, with each session lasting 45 minutes and designed to improve lower-extremity explosive power and dynamic functional mobility.
Sessions will include a 5-minute dynamic warm-up, 35 minutes of progressive plyometric exercises targeting vertical and horizontal force production, and a 5-minute cool-down.
Training will be individually supervised with safety measures including shock-absorbing flooring, cushioned footwear, technique monitoring, and standardized rest intervals.
Outros nomes:
|
|
Comparador Ativo: Standard Exercise Group
Participants received a 12-week supervised standard exercise program, twice weekly, with each session lasting 45 minutes.
Sessions focused on flexibility, aerobic conditioning, mobility, and basic lower-limb strengthening.
|
Participants in the control group will receive a 12-week supervised program, with each session lasting 45 minutes post-discharge burn rehabilitation program focusing on mobility, flexibility, aerobic conditioning, and basic lower-limb strengthening.
Sessions will include warm-up, stretching, moderate-intensity aerobic exercise at 50-70% of age-predicted maximum heart rate, strengthening exercises, and cool-down, with progression based on participant tolerance.
Outros nomes:
|
O que o estudo está medindo?
Medidas de resultados primários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
|
Lower-Limb Muscle Strength
Prazo: pre-intervention (Week 0)
|
Quadriceps and hamstring strength will be assessed using an isokinetic dynamometer.
After standardized positioning, stabilization, warm-up, and familiarization, participants will perform five maximal reciprocal knee extension/flexion repetitions.
The highest peak torque value (Nm) for hamstrings and quadriceps will be recorded.
|
pre-intervention (Week 0)
|
|
Lower-Limb Muscle Strength
Prazo: immediately post-intervention (Week 12)
|
Quadriceps and hamstring strength will be assessed using an isokinetic dynamometer.
After standardized positioning, stabilization, warm-up, and familiarization, participants will perform five maximal reciprocal knee extension/flexion repetitions.
The highest peak torque value (Nm) for hamstrings and quadriceps will be recorded.
|
immediately post-intervention (Week 12)
|
Medidas de resultados secundários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
|
Vertical Jump Height
Prazo: pre-intervention (Week 0)
|
Vertical Jump Test: Lower-limb explosive power will be assessed using a vertical jump performed on a force plate.
Participants will jump maximally with hands on hips to minimize arm contribution, completing three trials with 60 seconds of rest between trials.
The highest jump height will be recorded in centimeters.
|
pre-intervention (Week 0)
|
|
Vertical Jump Height
Prazo: immediately post-intervention (Week 12)
|
Vertical Jump Test: Lower-limb explosive power will be assessed using a vertical jump performed on a force plate.
Participants will jump maximally with hands on hips to minimize arm contribution, completing three trials with 60 seconds of rest between trials.
The highest jump height will be recorded in centimeters.
|
immediately post-intervention (Week 12)
|
|
Broad Jump Distance
Prazo: pre-intervention (Week 0)
|
Horizontal lower-limb power and dynamic leg strength will be assessed using the broad jump test.
Participants will perform three maximal two-footed forward jumps from a marked starting line, with 60 seconds of rest between trials.
The longest distance, measured from the starting line to the rearmost landing point, will be recorded in centimeters.
|
pre-intervention (Week 0)
|
|
Broad Jump Distance
Prazo: immediately post-intervention (Week 12)
|
Horizontal lower-limb power and dynamic leg strength will be assessed using the broad jump test.
Participants will perform three maximal two-footed forward jumps from a marked starting line, with 60 seconds of rest between trials.
The longest distance, measured from the starting line to the rearmost landing point, will be recorded in centimeters.
|
immediately post-intervention (Week 12)
|
|
Reactive Strength Index
Prazo: pre-intervention (Week 0)
|
Reactive strength will be assessed using a drop jump from a 30-cm box onto a force plate.
Three trials will be performed with 60 seconds of rest, and the highest reactive strength index value, calculated as jump height divided by ground contact time, will be recorded.
|
pre-intervention (Week 0)
|
|
Reactive Strength Index
Prazo: immediately post-intervention (Week 12)
|
Reactive strength will be assessed using a drop jump from a 30-cm box onto a force plate.
Three trials will be performed with 60 seconds of rest, and the highest reactive strength index value, calculated as jump height divided by ground contact time, will be recorded.
|
immediately post-intervention (Week 12)
|
|
Lower Extremity Functional Scale Score
Prazo: pre-intervention (Week 0)
|
Lower-limb functional ability will be assessed using the 20-item Lower Extremity Functional Scale, which evaluates perceived difficulty in activities such as walking, running, stair climbing, and squatting.
Each item is scored from 0 to 4, with a total score ranging from 0 to 80. Higher scores indicate better functional capacity.
|
pre-intervention (Week 0)
|
|
Lower Extremity Functional Scale Score
Prazo: immediately post-intervention (Week 12)
|
Lower-limb functional ability will be assessed using the 20-item Lower Extremity Functional Scale, which evaluates perceived difficulty in activities such as walking, running, stair climbing, and squatting.
Each item is scored from 0 to 4, with a total score ranging from 0 to 80. Higher scores indicate better functional capacity.
|
immediately post-intervention (Week 12)
|
|
Six-Minute Walk Test Distance
Prazo: pre-intervention (Week 0)
|
Functional exercise capacity will be assessed using the Six-Minute Walk Test performed along a 30-meter indoor corridor according to standardized guidelines.
Participants will be instructed to walk as far as possible, without running, within six minutes, and the total distance covered will be recorded in meters.
|
pre-intervention (Week 0)
|
|
Six-Minute Walk Test Distance
Prazo: immediately post-intervention (Week 12)
|
Functional exercise capacity will be assessed using the Six-Minute Walk Test performed along a 30-meter indoor corridor according to standardized guidelines.
Participants will be instructed to walk as far as possible, without running, within six minutes, and the total distance covered will be recorded in meters.
|
immediately post-intervention (Week 12)
|
|
Timed Up and Down Stairs Performance
Prazo: pre-intervention (Week 0)
|
Lower-limb power, agility, and dynamic balance will be assessed using the Timed Up and Down Stairs test.
Participants will ascend and descend 10 standard stairs as quickly and safely as possible, with two trials performed and the fastest time recorded in seconds.
|
pre-intervention (Week 0)
|
|
Timed Up and Down Stairs Performance
Prazo: immediately post-intervention (Week 12)
|
Lower-limb power, agility, and dynamic balance will be assessed using the Timed Up and Down Stairs test.
Participants will ascend and descend 10 standard stairs as quickly and safely as possible, with two trials performed and the fastest time recorded in seconds.
|
immediately post-intervention (Week 12)
|
|
4×10-Meter Shuttle Run Time
Prazo: pre-intervention (Week 0)
|
Agility and speed will be assessed using the 4×10-meter shuttle run test.
Participants will run back and forth between two cones placed 10 meters apart, completing four 10-meter segments for a total distance of 40 meters.
Two trials will be performed, and the fastest completion time will be recorded in seconds.
|
pre-intervention (Week 0)
|
|
4×10-Meter Shuttle Run Time
Prazo: immediately post-intervention (Week 12)
|
Agility and speed will be assessed using the 4×10-meter shuttle run test.
Participants will run back and forth between two cones placed 10 meters apart, completing four 10-meter segments for a total distance of 40 meters.
Two trials will be performed, and the fastest completion time will be recorded in seconds.
|
immediately post-intervention (Week 12)
|
|
Figure-of-8 Walk/Run Test Time
Prazo: pre-intervention (Week 0)
|
Dynamic balance, agility, and coordination will be assessed using the Figure-of-8 Walk/Run Test.
Participants will complete two full loops around two cones placed 5 meters apart as quickly as possible.
Two trials will be performed, and the fastest completion time will be recorded in seconds.
|
pre-intervention (Week 0)
|
|
Figure-of-8 Walk/Run Test Time
Prazo: immediately post-intervention (Week 12)
|
Dynamic balance, agility, and coordination will be assessed using the Figure-of-8 Walk/Run Test.
Participants will complete two full loops around two cones placed 5 meters apart as quickly as possible.
Two trials will be performed, and the fastest completion time will be recorded in seconds.
|
immediately post-intervention (Week 12)
|
Colaboradores e Investigadores
É aqui que você encontrará pessoas e organizações envolvidas com este estudo.
Patrocinador
Colaboradores
Investigadores
- Diretor de estudo: Maged A Basha, PhD, Qassim University
Publicações e links úteis
A pessoa responsável por inserir informações sobre o estudo fornece voluntariamente essas publicações. Estes podem ser sobre qualquer coisa relacionada ao estudo.
Publicações Gerais
- Rivas E, Herndon DN, Cambiaso-Daniel J, Rontoyanni VG, Porter C, Glover S, Suman OE. Quantification of an Exercise Rehabilitation Program for Severely Burned Children: The Standard of Care at Shriners Hospitals for Children(R)-Galveston. J Burn Care Res. 2018 Oct 23;39(6):889-896. doi: 10.1093/jbcr/iry001.
- Neriamparambil AJ, Sawhney R, Wong WL. Evidence-Based Management of Burns: A Narrative Review of Evolving Practices. Eur Burn J. 2025 Nov 10;6(4):59. doi: 10.3390/ebj6040059.
- Elnaggar RK, Osailan AM, Alsubaie SF, Moawd SA, Abd El-Nabie WA. Graded aerobic exercise (GAEx): An effective exercise regimen to improve cardio-respiratory fitness and physical and psychosocial functioning in children with burn sequelae of the chest. Burns. 2022 Mar;48(2):337-344. doi: 10.1016/j.burns.2021.05.004. Epub 2021 May 13.
- Knuth CM, Auger C, Jeschke MG. Burn-induced hypermetabolism and skeletal muscle dysfunction. Am J Physiol Cell Physiol. 2021 Jul 1;321(1):C58-C71. doi: 10.1152/ajpcell.00106.2021. Epub 2021 Apr 28.
Datas de registro do estudo
Essas datas acompanham o progresso do registro do estudo e os envios de resumo dos resultados para ClinicalTrials.gov. Os registros do estudo e os resultados relatados são revisados pela National Library of Medicine (NLM) para garantir que atendam aos padrões específicos de controle de qualidade antes de serem publicados no site público.
Datas Principais do Estudo
Início do estudo (Real)
1 de abril de 2024
Conclusão Primária (Real)
25 de março de 2025
Conclusão do estudo (Real)
25 de março de 2025
Datas de inscrição no estudo
Enviado pela primeira vez
10 de maio de 2026
Enviado pela primeira vez que atendeu aos critérios de CQ
10 de maio de 2026
Primeira postagem (Real)
15 de maio de 2026
Atualizações de registro de estudo
Última Atualização Postada (Real)
15 de maio de 2026
Última atualização enviada que atendeu aos critérios de controle de qualidade
10 de maio de 2026
Última verificação
1 de maio de 2026
Mais Informações
Termos relacionados a este estudo
Palavras-chave
Termos MeSH relevantes adicionais
- Manifestações Neurológicas
- Doenças musculoesqueléticas
- Doenças do Sistema Nervoso
- Doenças Musculares
- Manifestações Neuromusculares
- Ferimentos e Lesões
- Processos Patológicos
- Condições Patológicas, Sinais e Sintomas
- Sinais e sintomas
- Fraqueza muscular
- Queimaduras
- Atividade motora
- Movimento
- Fenômenos fisiológicos musculoesqueléticos
- Fenômenos fisiológicos musculoesqueléticos e neurais
- Terapêutica
- Modalidades de fisioterapia
- Atendimento ao paciente
- Terapia de exercícios
- Reabilitação
- Cuidados posteriores
- Continuidade do atendimento ao paciente
- Condicionamento físico, humano
- Exercício
- Exercício pliométrico
Outros números de identificação do estudo
- 2024-RHPT-017
Plano para dados de participantes individuais (IPD)
Planeja compartilhar dados de participantes individuais (IPD)?
SIM
Descrição do plano IPD
De-identified individual participant data supporting the published results will be available from the corresponding author upon reasonable request.
Prazo de Compartilhamento de IPD
6 months after publication
Critérios de acesso de compartilhamento IPD
Requests will be reviewed for scientific relevance, methodological quality, and approval by all co-authors.
Data will be shared after approval and, if required, completion of a data-sharing agreement.
Tipo de informação de suporte de compartilhamento de IPD
- PROTOCOLO DE ESTUDO
Informações sobre medicamentos e dispositivos, documentos de estudo
Estuda um medicamento regulamentado pela FDA dos EUA
Não
Estuda um produto de dispositivo regulamentado pela FDA dos EUA
Não
Essas informações foram obtidas diretamente do site clinicaltrials.gov sem nenhuma alteração. Se você tiver alguma solicitação para alterar, remover ou atualizar os detalhes do seu estudo, entre em contato com register@clinicaltrials.gov. Assim que uma alteração for implementada em clinicaltrials.gov, ela também será atualizada automaticamente em nosso site .