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Serrated Inferior Turbinate Variation and Sinonasal Findings on CBCT

28 de julho de 2026 atualizado por: DİLARA NİL GÜNAÇAR, Recep Tayyip Erdogan University Training and Research Hospital

Evaluation of the Relationship Between Serrated Inferior Turbinate Variation, Maxillary Sinus Mucosal Thickness, and Sinonasal Anatomical Structures Using Cone-Beam Computed Tomography

regulate nasal airflow, humidify and filter inspired air. Serrated inferior turbinate is a rare anatomical variation characterized by an irregular, serrated appearance of the inferior turbinate bone. Although this variation has been described in radiological studies, its possible relationship with maxillary sinus mucosal changes and other sinonasal anatomical features remains unclear.

This retrospective observational study aims to evaluate the relationship between serrated inferior turbinate variation and maxillary sinus mucosal thickness, mucosal abnormalities, and other sinonasal anatomical structures using cone-beam computed tomography (CBCT) images.

CBCT images obtained from patients who underwent imaging for routine diagnostic purposes will be retrospectively reviewed. The presence of serrated inferior turbinate variation, maxillary sinus findings, inferior turbinate measurements, and nasal septum characteristics will be evaluated.

The study aims to improve understanding of the radiological significance of serrated inferior turbinate variation and to provide information that may contribute to more accurate evaluation and reporting of sinonasal anatomical variations.

Visão geral do estudo

Status

Ainda não está recrutando

Descrição detalhada

The nasal cavity contains several anatomical structures that contribute to normal respiratory function, including regulation of airflow, filtration, humidification, and temperature control of inspired air. The inferior turbinate is a key component of the lateral nasal wall and consists of a bony framework covered by vascular mucosa. Variations in the morphology and dimensions of the inferior turbinate may influence nasal airflow and the anatomical relationship between the nasal cavity and adjacent sinonasal structures.

Serrated inferior turbinate is a rare anatomical variation characterized by irregular serrated bony contours along the medial surface of the inferior turbinate. Previous studies have mainly focused on the prevalence and morphological description of inferior turbinate variations; however, the potential association between serrated inferior turbinate variation and maxillary sinus mucosal changes has not been sufficiently investigated.

Cone-beam computed tomography (CBCT) provides three-dimensional, high-resolution imaging of the maxillofacial region and allows detailed assessment of bony structures, paranasal sinuses, and sinonasal anatomical variations. In this study, CBCT images will be retrospectively analyzed to determine whether the presence of serrated inferior turbinate variation is associated with changes in the ipsilateral maxillary sinus mucosa and other sinonasal anatomical parameters.

The study population will consist of individuals who underwent CBCT imaging for routine diagnostic purposes. Images will be evaluated for the presence or absence of serrated inferior turbinate variation. Additional radiological assessments will include maxillary sinus mucosal thickness, presence of polypoid mucosal thickening or retention cysts, inferior turbinate dimensions, nasal septal deviation angle, and other sinonasal anatomical findings.

All evaluations will be performed on existing CBCT datasets without additional imaging procedures or interventions. Patient confidentiality will be maintained throughout the study, and all analyses will be performed using anonymized imaging data.

The findings of this study may contribute to a better understanding of the clinical and radiological significance of serrated inferior turbinate variation and may improve the assessment and reporting of sinonasal anatomical variations in CBCT examinations.

Tipo de estudo

Observacional

Inscrição (Estimado)

105

Contactos e Locais

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Contato de estudo

Critérios de participação

Os pesquisadores procuram pessoas que se encaixem em uma determinada descrição, chamada de critérios de elegibilidade. Alguns exemplos desses critérios são a condição geral de saúde de uma pessoa ou tratamentos anteriores.

Critérios de elegibilidade

Idades elegíveis para estudo

  • Adulto
  • Adulto mais velho

Aceita Voluntários Saudáveis

Sim

Método de amostragem

Amostra Não Probabilística

População do estudo

The study population will consist of adult individuals aged 18-75 years who underwent cone-beam computed tomography (CBCT) imaging for routine diagnostic purposes at Recep Tayyip Erdoğan University, Faculty of Dentistry, Department of Oral and Maxillofacial Radiology between January 2025 and June 2026.

Existing CBCT images from the institutional radiology archive will be retrospectively reviewed. The study population will include individuals whose CBCT images provide adequate visualization of the maxillary sinuses, nasal cavity, ostiomeatal complex, and inferior turbinates for evaluation of sinonasal anatomical structures.

Patients with craniofacial anomalies, maxillofacial trauma, previous sinonasal surgery, pathological conditions affecting the evaluated anatomical structures, or CBCT images unsuitable for accurate assessment will be excluded.

The study aims to evaluate the relationship between serrated inferior turbinate variation, maxillary sinus mucosal thickness, and other sin

Descrição

Inclusion Criteria:

  • Individuals aged 18-75 years.
  • Patients who underwent cone-beam computed tomography (CBCT) imaging for routine diagnostic purposes between January 2025 and June 2026.
  • CBCT images including both maxillary sinuses, nasal cavity, ostiomeatal complex, and inferior turbinates.
  • CBCT images with sufficient diagnostic quality and clearly visible anatomical boundaries for evaluation and measurements.
  • CBCT images in which the anatomical landmarks required for nasal septal deviation angle measurement (crista galli, maxillary spine, and the most deviated point of the nasal septum) can be clearly identified.

Exclusion Criteria:

  • Patients with maxillofacial trauma, fractures, or conditions affecting the midface anatomy.
  • Patients with congenital craniofacial anomalies (e.g., cleft lip and palate) or syndromes affecting facial anatomy.
  • Patients with a history of sinonasal, inferior turbinate, or maxillary sinus surgery.
  • CBCT images with insufficient diagnostic quality, motion artifacts, or metal artifacts preventing accurate evaluation.
  • Patients with pathological lesions affecting the maxillary sinus or nasal cavity anatomy, including cysts, tumors, or aggressive inflammatory lesions.
  • CBCT findings suggestive of fungal sinusitis, including heterogeneous hyperdense contents, calcifications, bone expansion, or invasive changes.

Plano de estudo

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Como o estudo é projetado?

Detalhes do projeto

O que o estudo está medindo?

Medidas de resultados primários

Medida de resultado
Descrição da medida
Prazo
Maxillary sinus mucosal thickness associated with serrated inferior turbinate variation
Prazo: At the time of CBCT image evaluation
The maximum mucosal thickness of the ipsilateral maxillary sinus will be measured in millimeters (mm) on cone-beam computed tomography (CBCT) images and compared between sides with serrated inferior turbinate variation and sides without this variation.
At the time of CBCT image evaluation

Medidas de resultados secundários

Medida de resultado
Descrição da medida
Prazo
Presence of polypoid mucosal thickening and mucous retention cysts in the maxillary sinus
Prazo: At the time of CBCT image evaluation
The presence or absence of polypoid mucosal thickening and mucous retention cysts in the maxillary sinus will be evaluated on CBCT images.
At the time of CBCT image evaluation

Colaboradores e Investigadores

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Datas de registro do estudo

Essas datas acompanham o progresso do registro do estudo e os envios de resumo dos resultados para ClinicalTrials.gov. Os registros do estudo e os resultados relatados são revisados ​​pela National Library of Medicine (NLM) para garantir que atendam aos padrões específicos de controle de qualidade antes de serem publicados no site público.

Datas Principais do Estudo

Início do estudo (Estimado)

15 de julho de 2026

Conclusão Primária (Estimado)

15 de agosto de 2026

Conclusão do estudo (Estimado)

30 de agosto de 2026

Datas de inscrição no estudo

Enviado pela primeira vez

28 de julho de 2026

Enviado pela primeira vez que atendeu aos critérios de CQ

28 de julho de 2026

Primeira postagem (Real)

31 de julho de 2026

Atualizações de registro de estudo

Última Atualização Postada (Real)

31 de julho de 2026

Última atualização enviada que atendeu aos critérios de controle de qualidade

28 de julho de 2026

Última verificação

1 de julho de 2026

Mais Informações

Termos relacionados a este estudo

Outros números de identificação do estudo

  • 2026/297

Informações sobre medicamentos e dispositivos, documentos de estudo

Estuda um medicamento regulamentado pela FDA dos EUA

Não

Estuda um produto de dispositivo regulamentado pela FDA dos EUA

Não

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