Effect of Nail Biting Habit on Mandibular Bone Structure: A Retrospective Radiological Study
31 de julho de 2026 atualizado por: DİLARA NİL GÜNAÇAR, Recep Tayyip Erdogan University Training and Research Hospital
Evaluation of the Effects of Nail Biting Habit on Mandibular Bone Structure Using Fractal Analysis and Panoramic Morphometric Indices: A Retrospective Radiological Study
Nail biting (onychophagia) is a common parafunctional habit characterized by repetitive and non-functional biting behavior.
Although the effects of nail biting on dental structures and occlusion have been reported, its potential effects on mandibular bone structure remain unclear.
This retrospective radiological study aims to evaluate the association between nail biting habit and mandibular bone characteristics using fractal analysis and panoramic morphometric indices.
Existing panoramic radiographs of individuals with and without nail biting habits will be retrospectively analyzed.
Trabecular bone complexity, mandibular cortical width, panoramic mandibular index, and Klemetti index values will be compared between groups to investigate whether nail biting habit is associated with alterations in mandibular bone morphology.
Visão geral do estudo
Status
Ainda não está recrutando
Condições
Descrição detalhada
Nail biting (onychophagia) is classified as a body-focused repetitive behavior and represents a common parafunctional habit, particularly among children and adolescents. Continuous repetitive mechanical forces generated during nail biting may affect the stomatognathic system; however, the possible effects of this habit on mandibular bone structure have not been sufficiently investigated.
Fractal analysis is a radiological assessment method used to evaluate trabecular bone architecture by quantifying structural complexity. Higher fractal dimension values indicate increased complexity of bone patterns. In addition, panoramic morphometric indices such as mandibular cortical width, panoramic mandibular index, and Klemetti index provide information regarding cortical bone quality and quantity.
In this retrospective case-control study, existing panoramic radiographs of individuals with and without nail biting habits will be evaluated. Radiological parameters including fractal dimension, mandibular cortical width, panoramic mandibular index, and Klemetti index will be compared between groups. This study aims to determine whether nail biting habit is associated with measurable changes in mandibular trabecular and cortical bone characteristics.
Tipo de estudo
Observacional
Inscrição (Estimado)
100
Contactos e Locais
Esta seção fornece os detalhes de contato para aqueles que conduzem o estudo e informações sobre onde este estudo está sendo realizado.
Contato de estudo
- Nome: dilara nil günaçar
- Número de telefone: +905412940104
- E-mail: dilaranil.tomrukcu@erdogan.edu.tr
Critérios de participação
Os pesquisadores procuram pessoas que se encaixem em uma determinada descrição, chamada de critérios de elegibilidade. Alguns exemplos desses critérios são a condição geral de saúde de uma pessoa ou tratamentos anteriores.
Critérios de elegibilidade
Idades elegíveis para estudo
- Filho
Aceita Voluntários Saudáveis
Sim
Método de amostragem
Amostra Não Probabilística
População do estudo
The study population will consist of systemically healthy children aged 8-10 years who previously underwent routine dental examination at the Department of Pediatric Dentistry, Faculty of Dentistry, Recep Tayyip Erdoğan University.
Existing panoramic radiographs obtained during routine clinical care will be retrospectively analyzed.
Participants will be categorized into two groups according to the presence or absence of nail biting habit.
A minimum of 100 participants will be included, with equal distribution between the nail biting habit group and the control group and balanced sex distribution.
Mandibular bone characteristics will be evaluated using fractal dimension analysis and panoramic radiographic morphometric indices, including mandibular cortical width, panoramic mandibular index, mandibular cortical index (Klemetti index), and other mandibular bone measurements.
No intervention will be performed; only existing radiographic records will be assessed.
Descrição
Inclusion Criteria:
- Children aged 8-10 years who were examined at the Department of Pediatric Dentistry, Faculty of Dentistry, Recep Tayyip Erdoğan University.
- Systemically healthy participants.
- Participants with available diagnostic-quality panoramic radiographs obtained during routine dental examinations.
- Participants with and without a history of nail biting habit.
- Panoramic radiographs with sufficient image quality for fractal dimension analysis and mandibular morphometric measurements.
- Radiographs without periapical pathology in teeth adjacent to the regions of interest (ROI) used for fractal analysis.
- Participants with at least 20 existing teeth.
- Radiographic records with available parental radiographic information and consent documentation.
Exclusion Criteria:
- Participants with systemic diseases or conditions that may affect bone metabolism, including diabetes mellitus, osteoporosis, osteomalacia, renal diseases, hypothyroidism, or hyperparathyroidism.
- Participants using medications that may influence bone density or bone metabolism.
- Participants with temporomandibular joint disorders affecting the subcondylar region.
- Participants with mandibular pathological conditions, including cysts, tumors, or other lesions affecting mandibular bone structure.
- Participants with periapical pathology adjacent to the regions selected for fractal analysis.
- Participants with fewer than 20 teeth.
- Panoramic radiographs with insufficient diagnostic quality or image artifacts that prevent reliable measurements.
- Radiographs that do not allow accurate evaluation of mandibular cortical and trabecular bone parameters.
Plano de estudo
Esta seção fornece detalhes do plano de estudo, incluindo como o estudo é projetado e o que o estudo está medindo.
Como o estudo é projetado?
Detalhes do projeto
Coortes e Intervenções
Grupo / Coorte |
|---|
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Nail Biting Habit Group
This cohort includes systemically healthy children aged 8-10 years with a documented nail biting habit.
Existing panoramic radiographs obtained during routine dental examinations will be retrospectively analyzed.
Mandibular trabecular bone structure will be evaluated using fractal dimension analysis, and cortical bone characteristics will be assessed using mandibular cortical width, panoramic mandibular index, and Klemetti index measurements.
No intervention will be performed.
|
|
Control Group Without Nail Biting Habit
This cohort includes systemically healthy children aged 8-10 years without a history of nail biting habit.
Existing panoramic radiographs obtained during routine dental examinations will be retrospectively analyzed using the same radiological evaluation methods.
Mandibular trabecular and cortical bone characteristics will be compared with those of the nail biting habit group.
No intervention will be performed.
|
O que o estudo está medindo?
Medidas de resultados primários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
|
Mandibular Trabecular Bone Structure Assessed by Fractal Dimension Analysis
Prazo: Baseline
|
Mandibular trabecular bone architecture will be evaluated using fractal dimension analysis on panoramic radiographs.
Fractal dimension measurements will be performed using the box-counting method described by White and Rudolph.
Four regions of interest (ROIs) in the mandible will be analyzed, including the condylar subcortical region, supracortical region above the mandibular angle, area above the mandibular canal distal to the mental foramen, and anterior region of the mental foramen.
Measurements will be performed bilaterally, and the mean fractal dimension value will be calculated for each participant.
Higher fractal dimension values indicate greater trabecular bone complexity.
The fractal dimension values will be compared between individuals with and without nail biting habit.
|
Baseline
|
Medidas de resultados secundários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
|
Panoramic Mandibular Index (PMI)
Prazo: Baseline
|
The panoramic mandibular index (PMI) will be calculated on panoramic radiographs as the ratio of mandibular cortical width to the distance between the inferior border of the mandible and the inferior margin of the mental foramen.
Measurements will be performed bilaterally, and the mean value will be used for analysis.
|
Baseline
|
Colaboradores e Investigadores
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Datas de registro do estudo
Essas datas acompanham o progresso do registro do estudo e os envios de resumo dos resultados para ClinicalTrials.gov. Os registros do estudo e os resultados relatados são revisados pela National Library of Medicine (NLM) para garantir que atendam aos padrões específicos de controle de qualidade antes de serem publicados no site público.
Datas Principais do Estudo
Início do estudo (Estimado)
27 de julho de 2026
Conclusão Primária (Estimado)
5 de agosto de 2026
Conclusão do estudo (Estimado)
7 de agosto de 2026
Datas de inscrição no estudo
Enviado pela primeira vez
28 de julho de 2026
Enviado pela primeira vez que atendeu aos critérios de CQ
31 de julho de 2026
Primeira postagem (Real)
3 de agosto de 2026
Atualizações de registro de estudo
Última Atualização Postada (Real)
3 de agosto de 2026
Última atualização enviada que atendeu aos critérios de controle de qualidade
31 de julho de 2026
Última verificação
1 de julho de 2026
Mais Informações
Termos relacionados a este estudo
Termos MeSH relevantes adicionais
Outros números de identificação do estudo
- 2026/315
Informações sobre medicamentos e dispositivos, documentos de estudo
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