Effects of 3 Months of Supervised Exercise Training

Inclusion Criteria:

• Male Caucasian Adults between 30 and 65 years old Sedentary criteria based on the determination of fasting glucose (WHO 1999):
• normal if fasting plasma glucose (FPG) <1.10 g / l
• diabetes if fasting glucose> 1.26 g / l (7 mmol / l) twice
• nondiabetic fasting hyperglycemia: 1.10 g / l ≤ FPG ≤ 1.26 g / l
• glucose intolerance : if plasma glucose at 120 minutes during the OGTT (75g) is between 1.40 g / l and 2 g/ l.

Body mass index 25 BMI 35kg/m2 Affiliated to National Health Insurance Subject giving his written informed consent Subject considered as normal after clinical examination and medical questionnaire

Exclusion Criteria:

• - drugs that interfere with the parameters determined
• diabetic treated with insulin, glitazones or glinides
• eating disorders like bulimia and vomiting
• special diet, vegan or vegetarian
• autoimmune disease or inflammatory progressive desease requiring prolonged treatment
• regular physical activity (> 1 hour of physical activity per week for at least 6 months)
• smoking (> 5 cigarettes / day)
• weight change greater than 5% of the total weight in the 3 months preceding the study
• contra-indication to physical activity
• chronic pathologies: cancer, inflammatory, cardiac, pulmonary, renal, gastrointestinal or liver diseases
• Being in exclusion on the National Volunteers Data file
• No one under guardianship or not subject to social security.
• Being under someone's supervision
• Subjects deprived of their liberty by judicial or administrative.
• Refusal to sign the information sheet and written consent for particip