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Growing Right Onto Wellness (GROW): Changing Early Childhood Body Mass Index (BMI) Trajectories (GROW)

2021年9月30日 更新者:Shari Barkin, MD, MSHS、Vanderbilt University
The purpose of this study is to conduct a randomized controlled trial that examines how a family based, community centered intervention effects early childhood BMI trajectories.

研究概览

详细说明

Increases in sedentary lifestyle and high calorie food consumption, among other factors, have contributed to epidemic levels of childhood obesity in the US. Children who are overweight during the preschool period are more likely to become overweight adolescents and obese adults. Food preferences and activity habits set in early childhood can profoundly influence lifelong trajectories for Body Mass Index (BMI) and health. Specifically, rapid BMI gain in early childhood has been established to affect adulthood mortality and morbidity. Unfortunately, the longer such unhealthy patterns are in place, the more difficult it can be to reverse them. Therefore, healthy lifestyle interventions targeted at children as early as preschool have enormous potential to affect lifelong health. Furthermore, nutrition and activity patterns are determined not only at the child level, but within the family and the community.

This study will assess the impact of a family-based and community centered multilevel behavioral intervention addressing nutrition and physical activity with high risk parent-preschool children dyads to promote pediatric obesity prevention. The 7 year study will follow 600 parent preschool child dyads, half of whom will be randomized into the intervention condition which will utilize a health literate approach, build new social networks, utilize behavior modification tools including goal setting, self monitoring, and problem solving, and create behavior-environmental synergy with cues to action for use of the built environment for healthy behaviors. Both the intervention and control group (separately) will receive the control condition in which parent-child dyads will receive a literacy promotion/school success curriculum.

The primary outcome of interest will be early childhood BMI trajectories measured at multiple time points over the three year RCT. Additional measures collected throughout the study from children and parents will include: tricep skin fold, waist circumference, actigraphy, 3-day diet recalls, questionnaires, social network data, and saliva to assess a genetics/epigenetics associated with obesity. Consistent with a multilevel systems approach, the investigators will develop and assess built environment changes related to obesity prevention. Moreover, working with the study's community partners, the investigators will evaluate how this approach affects local policy.

研究类型

介入性

注册 (实际的)

610

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • Tennessee
      • Nashville、Tennessee、美国、37232
        • Vanderbilt University Medical Center

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

3年 至 5年 (孩子)

接受健康志愿者

是的

有资格学习的性别

全部

描述

Inclusion Criteria:

  • English or Spanish speaking
  • Address in select zip code regions around participating Metro community centers
  • Parental commitment to consistent participation
  • Consistent phone access for 3 years
  • Child aged 3-5 years old
  • Child BMI ≥ 50% and < 95% (no diagnosis of failure to thrive or difficulty with appropriate weight gain)
  • Healthy parent and child (without medical conditions necessitating limited physical activity)
  • Parent ≥ 18 years of age

Exclusion Criteria:

  • Non English or Spanish speaking
  • Address outside select zip code regions around participating Metro community centers
  • Lack of parental commitment to consistent participation
  • Lack of consistent phone access
  • Child outside specified age range
  • Child BMI < 50% or ≥ 95%
  • Parents and/or children who are diagnosed with medical illnesses where regular exercise might be contraindicated
  • Parent < 18 years of age

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:预防
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:无(打开标签)

武器和干预

参与者组/臂
干预/治疗
有源比较器:GROW Smarter
Library based program to promote early literacy
Group sessions that meet six times over the course of three years with quarterly newsletters.
实验性的:GROW Healthier
Healthy lifestyle intervention focused on building healthy lifestyle skills for preschool children and participating parents and building new social networks between the intervention group members.
Group sessions that meet six times over the course of three years with quarterly newsletters.
Group sessions that meet once weekly for 3 months (intensive phase) with choice of phone call session as preferred by participant, phone call coaching monthly for 9 months (maintenance phase), and monthly cues to action to use one's built environment for healthy activities for 24 months (sustainability phase)

研究衡量的是什么?

主要结果指标

结果测量
大体时间
Early Childhood BMI Trajectory
大体时间:Baseline, 3 months, 9 months, 12 months, 24 months, and 36 months
Baseline, 3 months, 9 months, 12 months, 24 months, and 36 months

次要结果测量

结果测量
措施说明
大体时间
Average daily energy intake (kcal)
大体时间:Baseline, 12 months, 24 months, and 36 months
Baseline, 12 months, 24 months, and 36 months
Percentage of Energy Intake from Fat
大体时间:Baseline, 12 months, 24 months, and 36 months
Baseline, 12 months, 24 months, and 36 months
Percentage of Energy Intake from Carbohydrates
大体时间:Baseline, 12 months, 24 months, and 36 months
Baseline, 12 months, 24 months, and 36 months
Percentage of Energy Intake from Protein
大体时间:Baseline, 12 months, 24 months, and 36 months
Baseline, 12 months, 24 months, and 36 months
Average daily time (minutes) spent in rest and sedentary behavior
大体时间:Baseline, 12 months, 24 months, and 36 months
Baseline, 12 months, 24 months, and 36 months
Average daily time (minutes) spent in moderate and vigorous physical activity
大体时间:Baseline, 12 months, 24 months, and 36 months
Baseline, 12 months, 24 months, and 36 months
Parent community center use with child
大体时间:Baseline, 12 months, 24 months, and 36 months
never versus at least once
Baseline, 12 months, 24 months, and 36 months
Parent BMI
大体时间:Baseline, 3 months, 9 months, 12 months, 24 months, and 36 months
Baseline, 3 months, 9 months, 12 months, 24 months, and 36 months
Parent Waist Circumference
大体时间:Baseline, 12 months, 24 months, and 36 months
Baseline, 12 months, 24 months, and 36 months
Parent Triceps Skinfold
大体时间:Baseline, 12 months, 24 months, and 36 months
Baseline, 12 months, 24 months, and 36 months
Child Waist Circumference
大体时间:Baseline, 12 months, 24 months, and 36 months
Baseline, 12 months, 24 months, and 36 months
Child Triceps Skinfold
大体时间:Baseline, 12 months, 24 months, and 36 months
Baseline, 12 months, 24 months, and 36 months

其他结果措施

结果测量
措施说明
大体时间
Social Network
大体时间:Baseline, 3 months, 12 months, and 36 months
Ties between participants
Baseline, 3 months, 12 months, and 36 months

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

一般刊物

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2011年6月1日

初级完成 (实际的)

2017年6月13日

研究完成 (实际的)

2017年7月6日

研究注册日期

首次提交

2011年3月3日

首先提交符合 QC 标准的

2011年3月15日

首次发布 (估计)

2011年3月16日

研究记录更新

最后更新发布 (实际的)

2021年10月8日

上次提交的符合 QC 标准的更新

2021年9月30日

最后验证

2021年9月1日

更多信息

与本研究相关的术语

其他研究编号

  • 100591
  • 5U01HL103620-03 (美国 NIH 拨款/合同)

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

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