Renal Function Determination in Patients With Liver Cirrhosis
Renal Function Determination With Creatinine and Cystatin C Dependent Formulas Compared to Gold Standard DTPA-TC-99 (Diethylene-triamine-pentaacetate- Technetium-99) in Mexican Cirrhotic Patients
We have several ways to appropriately determine renal function in healthy patients and in several diseases, in cirrhotic population we dont have a precise tool that has sufficient precision that reflects glomerular function, although it has been reported that cystatin C, because of its nature could improve diagnostic accuracy to determinate the renal function in this population.
The investigators hypothesize that glomerular filtration obtained from cystatin-C-derived formulas are more accurate when compared to creatinine-derived formulas with DTPA-Tc99 (diethylene-triamine-pentaacetate- technetium-99) as gold standard.
研究概览
地位
条件
详细说明
研究类型
注册 (实际的)
联系人和位置
学习地点
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DF
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Mexico City、DF、墨西哥、14000
- Instituto Nacional de Ciencias Médicas y Nutricion "Salvador Zubiran"
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Liver cirrhosis
- Stability in creatinine levels in the previous three months (variation <0.3 mg/dL)
- Signed informed consent
Exclusion Criteria:
- Pregnancy
- Hepatocellular carcinoma
- Cerebrovascular events
- Decompensated heart failure
- Drugs that modify serum creatinine levels
- Renal replacement therapy
学习计划
研究是如何设计的？
设计细节
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Levels of glomerular filtration through several formulas in cirrhotic patients
大体时间：Baseline
|
Determination of glomerular filtration through several formulas dependent of creatinine and cystatin C and the gold standard
|
Baseline
|
合作者和调查者
调查人员
- 研究主任：Aldo Torre, MD MSci、Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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