Measurement of Ocular Tensional Fluctuation by Triggerfish Lens Before and After Cataract Surgery in Patients With Exfoliative Glaucoma (TRIGGERFISH)
Glaucoma is a very frequent disease in Brittany. In glaucoma the retinal ganglion cells and their axons slowly die with visible changes at the optic nerve head (cupping). Without early diagnosis and effective treatment or with delayed treatment decrease of visual acuity or blindness become.
In secondary pseudoexfoliation glaucoma grayish-white deposits of abnormal proteins are found on all surfaces of eye irrigated by the aqueous humor. The deposits of PEX material inside the trabecular meshwork decrease aqueous humour outflow and the intraocular pression raise. The exfoliation material is found on the surface of the lens capsule with frequent developement of nuclear cataract . After cataract surgery the intra ocular pressure (IOP) decrease.
Some recent study have found decreasing ocular volume variation associated to IOP fluctuation in night after cataract surgery in normal pressure glaucoma patients. In our study we want see if it's the same thing in pseudoexfoliation glaucoma patients.
研究概览
地位
研究类型
注册 (实际的)
联系人和位置
学习地点
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Brest、法国、29609
- CHRU de Brest
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
取样方法
研究人群
描述
Inclusion Criteria:
- Adult
- Exfoliative glaucoma
- Patient who need cataract surgery
- Patient agree with study
Exclusion Criteria:
- Monophtalm patient
- Patient with bleb after glaucoma surgery
- Terminal glaucoma
- Herpes
- One year control impossible
学习计划
研究是如何设计的?
设计细节
- 观测模型:仅案例
- 时间观点:预期
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Measurement of ocular tensional fluctuation by Triggerfish lens before and after cataract surgery in patients with exfoliative glaucoma.
大体时间:During 24H00 before and after cataract surgery
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Variation of ocular volume
|
During 24H00 before and after cataract surgery
|
合作者和调查者
合作者
调查人员
- 首席研究员:Catherine COCHARD, Dr、University Hospital of Brest
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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