How Many Days Would You Want to Practice a Skill to Achieve it?
2020年10月23日 更新者：Sunnybrook Health Sciences Centre
Practice is required to improve your shot in basketball or to play a musical instrument.
The learning of these motor skills can be further enhanced by non-invasively stimulating regions of the brain that control movements with electrical currents.
These electric currents can strengthen or weaken connections of the brain, which consequently affects a person's ability to improve their performance on a skill.
Non-invasive brain stimulation (NIBS) is widely applied in many disciplines of neuroscience research, and has potential therapeutic application.
There are two specific types of NIBS that will be used in this research study: 1) Transcranial Direct Current Stimulation (tDCS), which applies very weak electrical currents via two rubber electrodes on the scalp, and 2) Transcranial Magnetic Stimulation (TMS), which applies magnetic pulses via a coil against the head, to stimulate regions of the brain.
Both types of non-invasive brain stimulation (i.e., tDCS, and TMS) are well-tolerated, painless, and safe.
The application of tDCS to brain regions that control movements, concurrently with practice of a skill, results in better skill performance, than practice alone with no tDCS.
Therefore, in this study, we will be testing different types of brain stimulation and different amounts of practice.
研究概览
研究类型
介入性
注册 (实际的)
27
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
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Ontario
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Toronto、Ontario、加拿大、M4N 3M5
- Sunnybrook Health Sciences Center
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参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
18年 至 44年 (成人)
接受健康志愿者
是的
有资格学习的性别
全部
描述
Inclusion Criteria:
- Healthy
Exclusion Criteria:
- prior history of neurological or psychiatric disease
- prior experience with the motor task used
- contraindications to TMS and TDCS (e.g., metal implants, history of seizures and headaches)
- musculoskeletal injury to upper limb
- drugs that interact with NIBS (e.g., antidepressants, antipsychotics, anticonvulsants)
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：基础科学
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Placebo Brain stimulation
Participants will receive Sham TDCS, and Transcranial Magnetic Stimulation (TMS)
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Placebo stimulation is applied to the left motor cortex while participants perform a motor task in the right hand.
During the motor task, participants use their right hand to pinch a force transducer that controls an on-screen cursor to navigate between a start position and a sequence of 5 other positions to the right.
Participants will receive Transcranial Magnetic Stimulation (TMS) to allow research investigators to determine the location of the left motor cortex.
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实验性的：Excitatory Brain Stimulation
Participants will receive Anodal TDCS, and Transcranial Magnetic Stimulation (TMS)
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Participants will receive Transcranial Magnetic Stimulation (TMS) to allow research investigators to determine the location of the left motor cortex.
Excitatory stimulation is applied to the left motor cortex while participants perform a motor task in the right hand.
During the motor task, participants use their right hand to pinch a force transducer that controls an on-screen cursor to navigate between a start position and a sequence of 5 other positions to the right.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Accuracy
大体时间：Up to 8 days
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Accuracy is defined as the proportion of trials per block with hits to all targets in the correct sequence order.
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Up to 8 days
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Speed
大体时间：Up to 8 days
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Speed is captured by the average sequence movement time per training block
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Up to 8 days
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员：Joyce Chen, PhD、Sunnybrook Research Institute
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2018年4月20日
初级完成 (实际的)
2020年8月31日
研究完成 (实际的)
2020年8月31日
研究注册日期
首次提交
2017年8月2日
首先提交符合 QC 标准的
2017年8月14日
首次发布 (实际的)
2017年8月15日
研究记录更新
最后更新发布 (实际的)
2020年10月27日
上次提交的符合 QC 标准的更新
2020年10月23日
最后验证
2020年10月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
运动学习的临床试验
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Cairo University招聘中
Sham TDCS的临床试验
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The Hong Kong Polytechnic UniversityThe University of Hong Kong; University of Magdeburg; University of Waterloo招聘中
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Weill Medical College of Cornell UniversityAmerican Heart Association招聘中
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I.R.C.C.S. Fondazione Santa LuciaCampus Bio-Medico University完全的
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Nanyang Technological UniversityMinistry of Education, Singapore; National Institute of Education, Singapore尚未招聘老化 | 执行功能 | 经颅直流电刺激 (tDCS) | 经颅电刺激
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Hebrew SeniorLifeNational Institute on Aging (NIA); Tel Aviv Medical Center招聘中
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University of New MexicoUniversity of Miami; The City College of New York; The Mind Research Network; New Jersey Institute... 和其他合作者完全的