Malnutrition is Not a Risk Factor for Free Flap Failure in the Oral Cavity (FOOD)
Free flap reconstruction consists in replacing tissular defect from one body part by another tissu harvested in a distant site. Microsurgery has to be performed to restore vascularization.
Free flaps are now the gold standard in complex reconstruction. While reliable with a success rate superior to 95 %, a failure takes a heavy burden on the patient. Many risk factors have been highlitghted in free flap failure for head and neck microvascular reconstruction.
Among them, malnutrition is still debated. This is a retrospective cohort study comparing complications occurrence between two groups. One group with normal nutritionnal status, the other with malnutrition. Between january 2008 and january 2018, 70 patients who underwent oral cavity reconstruction using free flap were included. This is the first study known to date which uses clinical and biological variables to determine the nutritionnal status.
Malnutrition is not associated with a higher risk for free flap failure in the oral cavity.
研究概览
研究类型
注册 (实际的)
联系人和位置
学习地点
-
-
-
Dijon、法国、21000
- CHU Dijon Bourgogne
-
-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- every consenting patients undergoing free flap reconstruction of the oral cavity
Exclusion Criteria:
- unable to give consent
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
|
None-malnutrition
normal nutritionnal status
|
Free flap reconstruction of the oral cavity
|
|
Malnutrition
|
Free flap reconstruction of the oral cavity
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Major complication occurency
大体时间：1 month
|
in the first-month post-operative period, complications leading to flap loss
|
1 month
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Minor complication occurency
大体时间：1 month
|
in the first-month post-operative period, complications NOT leading to flap loss
|
1 month
|
合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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