Role of Hematological Parameters in the Stratification of COVID-19 Disease Severity
研究概览
详细说明
Objective:
COVID-19 virus involves respiratory as well as other body systems including cardiovascular, gastrointestinal, neurological, immunological and hematopoietic system. Patient of covid-19 pneumonia presents with wide range of hemostatic abnormalities. These hemostatic abnormalities in COVID-19 are related with disease progression, severity and mortality. The Objective of our study is to evaluate the role of hematological parameters in determination of COVID-19 disease severity.
Material and Method:
This was a retrospective study, conducted in Department of Pathology and Department of medicine, FMH college of Medicine and Dentistry from May 2020 to July 2020. Total of 101, confirmed cases of covid-19 disease, both genders between 17 to 75-year age were included. Hematological parameters were compared in mild, moderate, severe and critical disease group. Continuous variables were analyzed by using non parametric, Kruskal Wallis test while categorical variables were analyzed by chi-square test.
研究类型
注册 (实际的)
联系人和位置
学习地点
-
-
Punjab
-
Lahore、Punjab、巴基斯坦、54000
- FMH college of medicine and dentistry
-
-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- diagnosed cases of covid-19 disease
- Both genders
- 17 to 75 year age
Exclusion Criteria:
- known case of chronic liver disease
- known hematological diseases were excluded
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
|
Covid-19 disease severity
Mild, moderate, severe and critical disease
|
Diagnostic tests( hematological parameters) were assessed.
|
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
complete blood count- Hemoglobin. White blood count, platelet count, Neutrophil to lymphocyte ratio
大体时间:3 months
|
disease severity was assessed on basis of hematological parameters.
|
3 months
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
PT, APTT and D-dimer
大体时间:3 months
|
improvement in PT, APTT and D-dimer levels were assessed
|
3 months
|
其他结果措施
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
LDH, serum ferritin level
大体时间:3 months
|
improvement in LDH and were assessed
|
3 months
|
合作者和调查者
调查人员
- 学习椅:Ayaz Lone, MBBS,FCPS、FMH college of medicine and dentistry
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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