The Relation Between Abdominal Obesity, Type 2 Diabetes Mellitus and Knee Osteoarthritis
Background:Knee osteoarthritis is more common in patients with type-2 diabetes mellitus, however it is not known whether this effect is caused by diabetes itself or concominant abdominal obesity.
Objectives:The aim of this study is to determine whether type-2 diabetes itself, independent of abdominal obesity, is a risk factor for femoral cartilage, knee osteoarthritis and poor quality of life.
Design:A cross-sectional design. Settings:Training and research hospital in Turkey. Patients and Methods:Female patients was enrolled in this study and divided into two groups: according to presence or absence of diabetes. Later, both the patients with and without abdominal obesity was divided into two groups according the presence of diabetes.
Main Outcome measures:Clinical parameters were visual analog-scale, gait speed and short form-36. Knee radiographs were evaluated according to Kellgren Lawrance-Scale. And ultrasonography parameters were the measurements of distal femoral cartilage thickness.
Sample size:126
研究概览
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
-
-
-
Eskişehir、火鸡
- Eskişehir City Hospital
-
-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- being female
- aged between 40 and 70.
Exclusion Criteria:
- Patients with any concomitant chronic disease
- rheumatoid arthritis
- cardiac diseases (except type 2 diabetes mellitus and hypertension)
- knee surgery
- trauma
- bone mass or cancer
- inflammatory arthritis
- impaired cognitive status
- immobilized patients
- type 1 diabetes mellitus
学习计划
研究是如何设计的？
设计细节
- 主要用途：放映
- 分配：非随机化
- 介入模型：并行分配
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的：Patients with type 2 diabetes
Patients with diabetes mellitus was evaluated in terms of pain scores and ultrasonographic femoral cartilage thickness and retrospective radiographic knee osteoarthritis scores.
|
The knees of all patients were screened with ultrasonography device for the measurement of femoral cartilage thicknesses.
|
|
其他：Patients without type 2 diabetes
Patients without diabetes mellitus was evaluated in terms of pain scores and ultrasonographic femoral cartilage thickness and retrospective radiographic knee osteoarthritis scores.
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The knees of all patients were screened with ultrasonography device for the measurement of femoral cartilage thicknesses.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Femoral cartilage thickness
大体时间：baseline
|
Measured by ultrasonography (higher value:thick cartilage, lower value:thin cartilage)
|
baseline
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
visual analog scale
大体时间：baseline
|
pain measurement (point 0 to 10) 0:worse pain 10:no pain
|
baseline
|
|
radiographic knee osteoarthritis
大体时间：baseline
|
evaluated by kellgren lawrance scale.(0-4)
0:no osteoarthritis, 4: severe osteoarthritis
|
baseline
|
合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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