The Effect of Stretching Exercises on Vascular Function, Blood Flow, and Walking Function in Middle and Older Adults
2021年4月29日 更新者：Mei-Wun Tsai、National Yang Ming University
This study examines the relationship between circulation and walking speed after performing 8-week stretching exercises.
研究概览
详细说明
This study examines the relationship between circulations and walking speeds.
Most studies in the field of stretching exercises have only focused on improvements of endothelial functions in younger population; however, I aim to emphasize its effects on different populations, such as people with frailty, low physical activity level, weakness and postoperative status.
Previous research has established that stretching exercises can improve walking function by modulations of musculoskeletal or neuromuscular system.
The importance and originality of this study are that it explores the relationship between circulation and walking speed.
Due to the inability to extrapolate outcomes; short-term effect of improved blood vessel function; the unclear mechanism of stretching exercises; and considering the different physical fitness groups, I design a home-based, low-dose, and anatomic chain-based stretching exercises to verify the possible mechanism and effects.
研究类型
介入性
注册 (预期的)
48
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习联系方式
- 姓名：Mei-Wun Tsai, Ph.D
- 电话号码：+886+2+28267939
- 邮箱：tmwk@ym.edu.tw
学习地点
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-
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Taipei、台湾、112
- 招聘中
- National Yang Ming University
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接触：
- Mei-Wun Tsai, Ph.D
-
接触：
- Liang-Ying Lai
-
首席研究员：
- Liang-Ying Lai
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-
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
20年 至 85年 (成人、年长者)
接受健康志愿者
不
有资格学习的性别
全部
描述
Inclusion Criteria:
- age between 20-85 years old
- Follow instructions
- Walk with/without assistive technology
Exclusion Criteria:
- Unstable acute or chronic health conditions
- Peripheral vascular diseases
- Non-musculoskeletal problems that would limit stretching exercises
- Participate in other exercise programs
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：卫生服务研究
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Stretching exercises
Interventions are home-based stretching exercises.
The experimental group will receive 6 stretching exercises which stretch 20-30 seconds, relax for 10 seconds, and repeat 5 times for each side.
It will take 25-30 minutes every day for continuous 8 weeks.
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Our interventions are home-based stretching exercises.
The experimental group will receive 6 stretching exercises which stretch 20-30 seconds, relax for 10 seconds, and repeat 5 times for each side.
It will take 25-30 minutes every day for continuous 8 weeks.
Those include stretching of the deep front line, spiral line, superficial front line, lateral line, superficial back line, and plantar flexors.
Designed concepts are the following three: 1) based on ''Anatomy- Train'' theory, 2) emphasize on movements of trunk and pelvis, and 3) stress on the stretching of lower extremities.
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无干预：Control group
Maintain their daily activity level in the 8 weeks.
We use the study desigh-''waiting list control'' in this group.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
vascular functions-Stiffness index(1)
大体时间：pre-intervention(1st week)
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(Stiffness index, SI，unit：m/s)
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pre-intervention(1st week)
|
|
vascular functions-Stiffness index(2)
大体时间：during intervention(4th week)
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(Stiffness index, SI，unit：m/s)
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during intervention(4th week)
|
|
vascular functions-Stiffness index(3)
大体时间：post-intervention(8th week)
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(Stiffness index, SI，unit：m/s)
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post-intervention(8th week)
|
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vascular functions-Reflective index(1)
大体时间：pre-intervention(1st week)
|
(Reflective index, RI，unit：％)
|
pre-intervention(1st week)
|
|
vascular functions-Reflective index(2)
大体时间：during intervention(4th week)
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(Reflective index, RI，unit：％)
|
during intervention(4th week)
|
|
vascular functions-Reflective index(3)
大体时间：post-intervention(8th week)
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(Reflective index, RI，unit：％)
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post-intervention(8th week)
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vascular functions-Vascular age
大体时间：pre-intervention(1st week)
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(Vascular age, VA，unit：year-old)
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pre-intervention(1st week)
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Ultrasound parameters-peak-systolic velocity(1)
大体时间：pre-intervention(1st week)
|
（peak-systolic velocity, PSV)
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pre-intervention(1st week)
|
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Ultrasound parameters-peak-systolic velocity(2)
大体时间：during intervention(4th week)
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（peak-systolic velocity, PSV）
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during intervention(4th week)
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Ultrasound parameters-peak-systolic velocity(3)
大体时间：post-intervention(8th week)
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（peak-systolic velocity, PSV）
|
post-intervention(8th week)
|
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Ultrasound parameters-end-diastolic velocity(1)
大体时间：pre-intervention(1st week)
|
（end-diastolic velocity, EDV）
|
pre-intervention(1st week)
|
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Ultrasound parameters-end-diastolic velocity(2)
大体时间：during intervention(4th week)
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（end-diastolic velocity, EDV）
|
during intervention(4th week)
|
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Ultrasound parameters-end-diastolic velocity(3)
大体时间：post-intervention(8th week)
|
（end-diastolic velocity, EDV）
|
post-intervention(8th week)
|
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Ultrasound parameters-mean velocity(1)
大体时间：pre-intervention(1st week)
|
（mean velocity, mV）
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pre-intervention(1st week)
|
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Ultrasound parameters-mean velocity(2)
大体时间：during intervention(4th week)
|
（mean velocity, mV）
|
during intervention(4th week)
|
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Ultrasound parameters-mean velocity(3)
大体时间：post-intervention(8th week)
|
（mean velocity, mV）
|
post-intervention(8th week)
|
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Ultrasound parameters-mean volume flow(1)
大体时间：pre-intervention(1st week)
|
(mean volume flow, vFl)
|
pre-intervention(1st week)
|
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Ultrasound parameters-mean volume flow(2)
大体时间：during intervention(4th week)
|
(mean volume flow, vFl)
|
during intervention(4th week)
|
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Ultrasound parameters-mean volume flow(3)
大体时间：post-intervention(8th week)
|
(mean volume flow, vFl)
|
post-intervention(8th week)
|
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Ultrasound parameters-resistance index(1)
大体时间：pre-intervention(1st week)
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(resistance index, RI)
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pre-intervention(1st week)
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Ultrasound parameters-resistance index(2)
大体时间：during intervention(4th week)
|
(resistance index, RI)
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during intervention(4th week)
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Ultrasound parameters-resistance index(3)
大体时间：post-intervention(8th week)
|
(resistance index, RI)
|
post-intervention(8th week)
|
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Ultrasound parameters-pulsatility index(1)
大体时间：pre-intervention(1st week)
|
(pulsatility index, PI)
|
pre-intervention(1st week)
|
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Ultrasound parameters-pulsatility index(2)
大体时间：during intervention(4th week)
|
(pulsatility index, PI)
|
during intervention(4th week)
|
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Ultrasound parameters-pulsatility index(3)
大体时间：post-intervention(8th week)
|
(pulsatility index, PI)
|
post-intervention(8th week)
|
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Ultrasound parameters-diameter(1)
大体时间：pre-intervention(1st week)
|
（diameter, D）
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pre-intervention(1st week)
|
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Ultrasound parameters-diameter(2)
大体时间：during intervention(4th week)
|
（diameter, D）
|
during intervention(4th week)
|
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Ultrasound parameters-diameter(3)
大体时间：post-intervention(8th week)
|
（diameter, D）
|
post-intervention(8th week)
|
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Ultrasound parameters-area(1)
大体时间：pre-intervention(1st week)
|
（area, A）
|
pre-intervention(1st week)
|
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Ultrasound parameters-area(2)
大体时间：during intervention(4th week)
|
（area, A）
|
during intervention(4th week)
|
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Ultrasound parameters-area(3)
大体时间：post-intervention(8th week)
|
（area, A）
|
post-intervention(8th week)
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walking speed-preferred(1)
大体时间：pre-intervention(1st week)
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Timed 10-Meter Walk Test (preferred)
|
pre-intervention(1st week)
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walking speed-preferred(2)
大体时间：during intervention(4th week)
|
Timed 10-Meter Walk Test (preferred)
|
during intervention(4th week)
|
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walking speed-preferred(3)
大体时间：post-intervention(8th week)
|
Timed 10-Meter Walk Test (preferred)
|
post-intervention(8th week)
|
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walking speed-fast(1)
大体时间：pre-intervention(1st week)
|
Timed 10-Meter Walk Test (fast)
|
pre-intervention(1st week)
|
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walking speed-fast(2)
大体时间：during intervention(4th week)
|
Timed 10-Meter Walk Test (fast)
|
during intervention(4th week)
|
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walking speed-fast(3)
大体时间：post-intervention(8th week)
|
Timed 10-Meter Walk Test (fast)
|
post-intervention(8th week)
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
body composition-height
大体时间：pre-intervention(1st week)
|
height(cm)
|
pre-intervention(1st week)
|
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body composition-weight
大体时间：pre-intervention(1st week)
|
weight(kg)
|
pre-intervention(1st week)
|
|
body composition-waist circumference
大体时间：pre-intervention(1st week)
|
waist circumference(cm)
|
pre-intervention(1st week)
|
|
vital sign-blood pressure(1)
大体时间：pre-intervention(1st week)
|
blood pressure(mmHg)
|
pre-intervention(1st week)
|
|
vital sign-blood pressure(2)
大体时间：during intervention(4th week)
|
blood pressure(mmHg)
|
during intervention(4th week)
|
|
vital sign-blood pressure(3)
大体时间：post-intervention(8th week)
|
blood pressure(mmHg)
|
post-intervention(8th week)
|
|
vital sign-heart rate(1)
大体时间：pre-intervention(1st week)
|
heart rate(bpm)
|
pre-intervention(1st week)
|
|
vital sign-heart rate(2)
大体时间：during intervention(4th week)
|
heart rate(bpm)
|
during intervention(4th week)
|
|
vital sign-heart rate(3)
大体时间：post-intervention(8th week)
|
heart rate(bpm)
|
post-intervention(8th week)
|
|
flexibility-chair sit and reach test (1)
大体时间：pre-intervention(1st week)
|
chair sit and reach test (cm)
|
pre-intervention(1st week)
|
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flexibility-chair sit and reach test (2)
大体时间：during intervention(4th week)
|
chair sit and reach test (cm)
|
during intervention(4th week)
|
|
flexibility-chair sit and reach test (3)
大体时间：post-intervention(8th week)
|
chair sit and reach test (cm)
|
post-intervention(8th week)
|
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grip strength
大体时间：pre-intervention(1st week)
|
hand dynamometer
|
pre-intervention(1st week)
|
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cognitive function
大体时间：pre-intervention(1st week)
|
Montreal Cognitive Assessment.Minimum value is 0 and maximum value is 30, and higher scores mean a better outcome
|
pre-intervention(1st week)
|
|
frailty
大体时间：pre-intervention(1st week)
|
SOF (Study of Osteoporotic Fractures).
Minimum value is 0 and maximum value is 3, and higher scores mean a worse outcome
|
pre-intervention(1st week)
|
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basic data
大体时间：pre-intervention(1st week)
|
gender, age, education, living status, smoking, and exercise habits
|
pre-intervention(1st week)
|
|
ACSM-PAR-Q+
大体时间：pre-intervention(1st week)
|
The Physical Activity Readiness Questionnaire for Everyone AND follow-up questions about their medical conditions (PAR-Q+) is used to identify whether subjects are at risk in engaging in exercises.
Thus, researchers can prescribe individual exercise prescriptions.
|
pre-intervention(1st week)
|
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IPAQ
大体时间：pre-intervention(1st week)
|
International Physical Activity Questionnaire to investigate their physical activity levels.
Higher the amount of physical activity (min-METs/week) means a more active life-style(physical activity level).
|
pre-intervention(1st week)
|
|
fitness
大体时间：pre-intervention(1st week)
|
(Duke activity status index, DASI) Minimum value is 0 and maximum value is 58.2, and higher scores mean a better physical activity level.
|
pre-intervention(1st week)
|
|
adherence of exercise
大体时间：post-intervention(8th week)
|
usage records from the Line app
|
post-intervention(8th week)
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员：Liang-Ying Lai、National Yang Ming University
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2020年9月1日
初级完成 (预期的)
2021年6月30日
研究完成 (预期的)
2021年6月30日
研究注册日期
首次提交
2021年4月26日
首先提交符合 QC 标准的
2021年4月29日
首次发布 (实际的)
2021年5月4日
研究记录更新
最后更新发布 (实际的)
2021年5月4日
上次提交的符合 QC 标准的更新
2021年4月29日
最后验证
2021年4月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.