Clinical Evaluation of Fenestration Decompression Combined With Secondary Curettage for Ameloblastoma of the Jaw: Retrospective Radiographic Analysis
Objectives: To investigate the outcomes of fenestration decompression combined with secondary curettage (FDSC) in the surgical treatment of jaw ameloblastoma.
Methods: Medical records of patients diagnosed as multicystic ameloblastoma (MA) or unicystic ameloblastoma (UA) by routine pathology were collected from January 2010 to December 2017 in Ninth People's Hospital, Shanghai JiaoTong University Medical College. Patients were divided into two groups based on the management regimen: FDSC group, and local curettage (LC) group. Patients were followed up for 3-8 years, using panoramic radiography to measure the change of the area of the cystic cavity involved in ameloblastoma and the recurrence or malignant transformation of the tumor in both groups. A total of 233 eligible patients were selected for provisional screening, including 145 patients with MA, and 88 patients with UA.
研究概览
地位
研究类型
注册 (实际的)
参与标准
资格标准
适合学习的年龄
- 孩子
- 成人
- 年长者
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
-Medical records of patients who were diagnosed with multicystic ameloblastoma (MA) or unicystic ameloblastoma (UA) by routine pathology were collected from January 2010 to December 2017 in Ninth People's Hospital of Shanghai JiaoTong University Medical College.
Exclusion Criteria:
- followed up less than 3 years
- For FDSC group, fenestration decompression failed
- recurrent ameloblastoma
- received other type of surgery;
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
|
Fenestration decompression combined with secondary curettage (FDSC)
Design of the opening window reasonably；Making cyst plug；secondary curettage
|
First，fenestration decompression was performed.
then, patients return every 3 months for follow up.
If the cystic cavity area was gradually reduced after one year of follow-up, patients should be considered for secondary curettage surgery.
|
|
local curettage (LC)
The tumor was removed by local curettage only
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Cystic cavity area reduction efficiency
大体时间：3 years after surgery
|
(good effect case number + moderate effect case number)/total case number
|
3 years after surgery
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Tumor recurrence rate
大体时间：3 years after surgery
|
the recurrence case number/total case number
|
3 years after surgery
|
其他结果措施
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
malignant transformation rate
大体时间：3 years after surgery
|
malignant transformation case number/total case number
|
3 years after surgery
|
合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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