Enhancing Readability of Lay Abstracts and Summaries for Medical Knowledge Using Generative Artificial Intelligence (BRIDGE AI 3)
Enhancing Readability of Lay Abstracts and Summaries for Medical Knowledge Using Generative Artificial Intelligence: A Randomized Controlled Trial (BRIDGE AI 3)
研究概览
详细说明
This study evaluates whether a generative artificial intelligence (AI) tool can improve the readability and accessibility of lay summaries derived from scientific medical abstracts. Many patients encounter difficulty understanding medical literature due to technical language and complexity, which can limit informed decision-making and engagement with healthcare information.
The BRIDGE-AI (Provider Perspective) initiative aims to address this gap by enabling healthcare professionals and researchers to generate patient-friendly summaries of scientific content using AI-assisted tools. The intervention leverages a generative AI framework (pub2people) designed to translate complex medical terminology into language that is understandable to a general audience.
In this randomized controlled study, participants with experience in scientific publishing will be assigned to either an AI-assisted group or a control group using conventional methods. Participants will be asked to transform scientific abstracts into layperson-friendly summaries. The study compares AI-assisted and manually generated outputs in terms of readability, accuracy, and efficiency.
The primary objective is to determine whether AI-assisted generation improves the readability of lay summaries compared to standard approaches. Secondary objectives include evaluating the accuracy of AI-generated summaries relative to source material and assessing potential time savings associated with AI use.
This study contributes to ongoing efforts to improve health communication by evaluating scalable tools that may enhance the translation of complex medical information into patient-accessible formats.
研究类型
注册 (实际的)
阶段
- 阶段2
联系人和位置
学习地点
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California
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Los Angeles、California、美国、91100
- University of Southern California
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参与标准
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
描述
Provider Participants
Inclusion:
- Corresponding authors who have been published in the top 10 journals of urology and medicine
- All genders
- Any profession
- 18+ years of age
Exclusion:
- Anyone under the age of 18
- Participants that have not published in the top 10 journals of urology and medicine
学习计划
研究是如何设计的？
设计细节
- 主要用途：卫生服务研究
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：单身的
武器和干预
参与者组/臂 |
干预/治疗 |
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无干预：Gold Standard
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实验性的：Pub2Post
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Pub2Post, a generative artificial intelligence agent which helps in drafting the layperson abstracts and summaries
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Readability Change
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Flesch Reading Ease Score Description: Measures text readability based on sentence length and word syllables. Scale: 0 to 100 Interpretation: Higher scores indicate easier readability (better outcome). |
The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Readability Change
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Flesch-Kincaid Grade Level Description: Estimates U.S. school grade level required to understand the text.
Scale: Typically ranges from ~0 to 18+ Interpretation: Lower scores indicate easier readability (better outcome).
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The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Readability Change
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Gunning Fog Index Description: Estimates years of formal education needed to understand the text on first reading. Scale: Typically 0 to 20+ Interpretation: Lower scores indicate easier readability (better outcome). |
The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Readability Change
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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SMOG Index (Simple Measure of Gobbledygook) Description: Estimates years of education required to comprehend the text.
Scale: Typically 0 to 20+ Interpretation: Lower scores indicate easier readability (better outcome).
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The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Readability Change
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Coleman-Liau Index Description: Readability formula based on characters per word and sentence length. Scale: Typically 0 to 18+ (grade level equivalent) Interpretation: Lower scores indicate easier readability (better outcome). |
The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Readability Change
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Automated Readability Index (ARI) Description: Estimates grade level required for comprehension using characters and word counts. Scale: Typically 0 to 14+ Interpretation: Lower scores indicate easier readability (better outcome). |
The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Time Saving
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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To evaluate the time savings achieved by using generative AI compared to traditional methods for generating layperson abstracts and summaries. Time will be recorded in hours, minutes, and seconds. We will collect and compare the total time spent drafting the complete layperson abstract and summaries, as well as the time spent on each individual section - background, methods, results, conclusion, and short summaries. The comparison will be made between summaries created by humans alone versus those created with GAI assistance. Time will be reported in minutes |
The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Correctness and meaning retention
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Accuracy Score of Layperson Abstract Sections Description: Degree to which each section (Background, Methods, Results, Conclusion, Short Summary) reflects key information from the original scientific abstract. Scale: 5-point Likert scale (1 = very inaccurate, 5 = highly accurate) Assessment Method: Two independent reviewers score each section Interpretation: Higher scores indicate better accuracy (better outcome). |
The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Correctness and meaning retention
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Completeness Score of Layperson Abstract Sections Description: Extent to which essential information from the original abstract is included in each section. Scale: 5-point Likert scale (1 = very incomplete, 5 = fully complete) Assessment Method: Two independent reviewers evaluate each section. Interpretation: Higher scores indicate greater completeness (better outcome). |
The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Correctness and meaning retention
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Clarity Score for Layperson Readability Description: Evaluates simplicity, avoidance of jargon, and coherence for lay audiences. Scale: 5-point Likert scale (1 = very unclear, 5 = very clear and understandable) Assessment Method: Two independent reviewers evaluate each section. Interpretation: Higher scores indicate better clarity (better outcome). |
The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Correctness and meaning retention
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Section-Level Correctness Rate Description: Proportion of sections rated as "correct," defined as receiving scores ≥4 from both reviewers on accuracy, completeness, and clarity simultaneously. Scale: 0 to 1 (proportion) or 0% to 100% Interpretation: Higher values indicate better overall section quality. |
The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Correctness and meaning retention
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Hallucination Rate Description: Frequency of false or misleading content in generated layperson abstracts, defined as information not supported by the original abstract. Scale: Proportion of sections or documents containing hallucinations (0 to 1 or %) Assessment Method: Evaluated separately by reviewers using predefined criteria. Interpretation: Lower values indicate better performance (fewer hallucinations). |
The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment.
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Perceived Task Difficulty
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment
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Description: Participant-reported difficulty of completing the lay abstract summarization task. Scale: 5-point Likert scale (1 = very easy, 5 = very difficult) (adjust anchors if different in your instrument) Assessment Timing: Immediately after task completion Interpretation: Lower scores indicate less perceived difficulty (better outcome) |
The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment
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Perceived Task Duration
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment
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Description: Participant perception of time required to complete the task.
Scale: 5-point Likert scale (1 = very short, 5 = very long) Assessment Timing: Post-task Interpretation: Lower scores indicate shorter perceived duration (better outcome)
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The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment
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Perceived Helpfulness of the intervention
大体时间：The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment
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Description: Participant-reported usefulness of the generative AI tool in assisting lay abstract creation. Scale: 5-point Likert scale (1 = not helpful at all, 5 = extremely helpful) Assessment Timing: Post-task Interpretation: Higher scores indicate greater perceived helpfulness (better outcome) |
The assessment will be conducted immediately after the study closes, which will occur 4 weeks after enrollment
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System Usability Scale (SUS) Score
大体时间：Immediately after completing the system/task (post-use assessment)
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Description: Standardized assessment of system usability using the System Usability Scale. Scale: 0 to 100 Interpretation: Higher scores indicate better usability
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Immediately after completing the system/task (post-use assessment)
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Perceived Usefulness (Technology Acceptance Model)
大体时间：Immediately after completing the system/task (post-use assessment)
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Description: Degree to which participants believe the GAI tool enhances task performance. Scale: Likert scale (typically 1-5 or 1-7; specify exact instrument version) Interpretation: Higher scores indicate greater perceived usefulness (better outcome) |
Immediately after completing the system/task (post-use assessment)
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Perceived Ease of Use (Technology Acceptance Model)
大体时间：Immediately after completing the system/task (post-use assessment)
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Description: Degree to which participants find the GAI tool easy to use.
Scale: Likert scale (typically 1-5 or 1-7; must match instrument used) Interpretation: Higher scores indicate greater ease of use (better outcome)
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Immediately after completing the system/task (post-use assessment)
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合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他相关的 MeSH 术语
其他研究编号
- UP-24-01142
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
IPD 共享支持信息类型
- 研究方案
- 树液
药物和器械信息、研究文件
研究美国 FDA 监管的药品
研究美国 FDA 监管的设备产品
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