Proof of Concept for Simulating Static Weight-bearing Exercises in the Supine Position (SWB_PoC)
Validation and Evaluation of a Static Supine Weight-Bearing Computed Tomography Method to Enable Detection of Implant Migration After Knee Arthroplasty
This project evaluates a new weight-bearing CT method to later improve early detection of implant migration after knee arthroplasty.
This method aims to allow patients to apply a controlled load during CT scanning, simulating standing conditions with real-time feedback.
The study has two phases. First, in healthy volunteers, biomechanical loading during prone simulated weight-bearing will be compared with a standard standing squat to validate the method. Second, in arthroplasty patients, standard radiographs will be compared with loaded and unloaded WBCT scans.
Patients will not deviate from the standard plan of care. The CT images are additions to the standard RX images and are not intended for diagnostic purposes to the patient.
The aim is to determine whether this method opens the door for more accurate and earlier detection of implant migration than current clinical imaging in the future, potentially improving long-term outcomes after knee arthroplasty.
研究概览
研究类型
注册 (估计的)
阶段
- 不适用
联系人和位置
学习联系方式
- 姓名：Nicolas Van Vlasselaer, Master
- 电话号码：555-5555
- 邮箱：nicolas.van.vlasselaer@vub.be
参与标准
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
描述
Inclusion Criteria:
- Healthy participants
- Patients with TKA
Exclusion Criteria:
- neurological conditions
- acute trauma
学习计划
研究是如何设计的？
设计细节
- 主要用途：诊断
- 分配：不适用
- 介入模型：单组作业
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的：Knee Arthroplasty
Patients with Knee Arthroplasty
|
Static supine weight bearing CT in addition to standard care RX
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Validation of static supine weight bearing against standing weight bearing using kinematic parameters
大体时间：1 year
|
Comparison of lower-limb and trunk joint kinematics between static supine weight-bearing and standing weight-bearing conditions in healthy subjects using marker-based motion capture. Unit of Measure: Degrees (°) |
1 year
|
|
Validation of static supine weight bearing against standing weight bearing using kinetic parameters
大体时间：1 Year
|
Comparison of ground reaction forces and joint moments between static supine weight-bearing and standing weight-bearing conditions in healthy subjects using force plate measurements. Unit of Measure: Newtons (N) and Newton-meters (Nm) |
1 Year
|
|
Validation of static supine weight bearing against standing weight bearing using muscle activation
大体时间：1 year
|
Comparison of lower-limb muscle activation patterns between static supine weight-bearing and standing weight-bearing conditions in healthy subjects using surface electromyography. Unit of Measure: Percentage of maximum voluntary contraction (%MVC) |
1 year
|
合作者和调查者
研究记录日期
研究主要日期
学习开始 (估计的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他研究编号
- 26015_SWB_PoC
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
药物和器械信息、研究文件
研究美国 FDA 监管的药品
研究美国 FDA 监管的设备产品
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