Three CT Signs of Nerve-root Suffering in Low-back Sciatica: a Study of Their Frequency in Patients Referred for CT-guided Nerve-root Infiltration.
2026年7月1日 更新者：Centre Hospitalier Universitaire de Nice
Prevalence of Three CT Signs of Nerve-root Suffering (Root Size Asymmetry/Hypertrophy, Peri-radicular Infiltration, Spontaneous Hyperdensity) in Patients With Low-back Sciatica Referred for CT-guided Foraminal Infiltration: a Single-centre Retrospective Study (Nice University Hospital - Pasteur 2).
Retrospective, observational, single-centre study conducted at Nice University Hospital (Pasteur 2), Department of Diagnostic and Interventional Radiology.
Objective: to assess the prevalence of three CT signs sought next to the clinically suspected nerve root in patients with low-back sciatica referred for CT-guided foraminal/peri-radicular infiltration: (1) nerve-root size asymmetry/hypertrophy, (2) peri-radicular infiltration, and (3) spontaneous root hyperdensity.
Hypothesis: these signs are associated with the suffering nerve root responsible for the clinical presentation.
Pre-infiltration planning CT scans (period 30 Jan 2024 - 11 Jul 2024) are reviewed by the operating radiologists (4th-, 5th- and 6th-year residents).
Target enrollment: 400 patients.
Data analysed to date: 104 patients / 105 infiltrations.
Preliminary prevalence: root asymmetry/hypertrophy 45.5%; peri-radicular infiltration 50.5%; spontaneous hyperdensity 23.8%; at least 2 of 3 signs 38.6%; all 3 signs 16.8%.
Mean age 65 years (range 25-93); approximately 62 women / 42 men; predominant levels L4-L5 and L5-S1.
研究概览
地位
招聘中
研究类型
观察性的
注册 (估计的)
400
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习联系方式
- 姓名：kevin desalos
- 电话号码：+ 33 06 87 63 05 74
- 邮箱：kevindesalos@gmail.com
学习地点
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Alpes Maritimes
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Nice、Alpes Maritimes、法国、06000
- 招聘中
- CHU NICE
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接触：
- kevin desalos
- 电话号码：+ 33 06 87 63 05 74
- 邮箱：kevindesalos@gmail.com
-
接触：
- CHU de Nice
- 电话号码：+33 06 87 63 05 74
- 邮箱：kevindesalos@gmail.com
-
-
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
不
取样方法
概率样本
研究人群
Patients referred to the Department of Diagnostic and Interventional Radiology of Pasteur 2 Hospital (Nice) for CT-guided infiltration of low-back sciatica, over the period 30 Jan 2024 to 11 Jul 2024.
描述
Inclusion Criteria:
- Adult (>= 18 years)
- Low-back sciatica / radicular pain with a systematized distribution
- Referred for CT-guided foraminal or peri-radicular infiltration at Pasteur 2 Hospital (Nice) between 30 Jan 2024 and 11 Jul 2024.
- Available and interpretable pre-infiltration planning CT
Exclusion Criteria:
- Planning CT missing or not interpretable
- Missing data on the three studied signs
- Radicular pain of tumoral, infectious or recent traumatic origin
- Spinal history precluding analysis of the studied root
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
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Patients with low-back sciatica referred for CT-guided infiltration
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Retrospective analysis of the planning CT scans performed before CT-guided foraminal/peri-radicular infiltration.
Reading by the operating radiologists (4th-, 5th- and 6th-year radiology residents) assessing, next to the symptomatic nerve root, three signs (present/absent): root size asymmetry/hypertrophy; peri-radicular infiltration; spontaneous hyperdensity.
No additional procedure for the patient.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Prevalence of nerve-root size asymmetry / hypertrophy on CT
大体时间：At inclusion
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Proportion of patients showing, on the pre-infiltration planning CT, size asymmetry (hypertrophy) of the nerve root next to the clinically suspected root (present/absent).
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At inclusion
|
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Prevalence of peri-radicular infiltration on CT
大体时间：At inclusion
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Proportion of patients showing, on the pre-infiltration planning CT, infiltration of the peri-radicular tissues next to the clinically suspected root (present/absent).
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At inclusion
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Prevalence of spontaneous nerve-root hyperdensity on CT
大体时间：At inclusion
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Proportion of patients showing, on the pre-infiltration planning CT, spontaneous hyperdensity of the nerve root next to the clinically suspected root (present/absent).
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At inclusion
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Pre-operative pain (VAS)
大体时间：Before the infiltration (Day 0).
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Visual analogue scale for pain, from 0 (no pain) to 10 (worst imaginable pain); a higher score indicates more severe pain.
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Before the infiltration (Day 0).
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Pre-operative quality of life (EQ-5D)
大体时间：Before the infiltration (Day 0).
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EQ-5D questionnaire covering 5 dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression).
Collected before the infiltration; used as the baseline health-state assessment.
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Before the infiltration (Day 0).
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2024年1月30日
初级完成 (实际的)
2026年3月4日
研究完成 (估计的)
2026年10月1日
研究注册日期
首次提交
2026年7月1日
首先提交符合 QC 标准的
2026年7月1日
首次发布 (实际的)
2026年7月8日
研究记录更新
最后更新发布 (实际的)
2026年7月8日
上次提交的符合 QC 标准的更新
2026年7月1日
最后验证
2026年6月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.