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Impact of a Short-Term Mediterranean-Style Diet on Health Indices (MEDWELL)

2026年7月15日 更新者:DR ADELE COSTABILE、University of Roehampton

Exploring the Effects of a Short-term Mediterranean-style Dietary Intervention on Indices of Mood and Wellbeing in UK Adults

Emerging evidence suggests protective properties of a Mediterranean diet (MD) in relation to prevention and management of mood disorders. However, there is paucity of dietary interventions investigating adherence to MD and effects on mood and wellbeing in individuals without a clinical diagnosis. The present study aimed to investigate the effects of adherence to a short-term MD on mood and wellbeing in healthy adults

研究概览

详细说明

This is a 1-week, cross-over, randomised, controlled study investigating the effects of Mediterranean style diet on perceived mood and overall wellbeing in healthy adults. The intervention consists following daily for 1 week a Mediterranean style eating pattern. Participants are following their habitual diet during the control week. This is an investigator-initiated, randomised, cross-over, controlled study.

研究类型

介入性

注册 (实际的)

22

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • UK
      • London、UK、英国、SW15 4JD
        • University of Roehampton, School of Life and Health Sciences

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人

接受健康志愿者

是的

描述

Inclusion Criteria:

  • Habitual diet of low Mediterranean Diet (MD)adherence i.e. individuals with MD scoring ≤7 (low adherence) were included.
  • Living in UK

Exclusion Criteria:

  • pregnant or breastfeeding following a weight loss diet
  • diagnosed medical condition (diabetes, cardiovascular disease, cancer, food allergies)
  • have any further health conditions which may cause you to react adversely whilst changing your diet.
  • diagnosed with a neurological impairment or psychiatric disorder
  • Current smoker (last 12 months)
  • history of substance abuse
  • taking dietary supplements
  • already following a Mediterranean style diet

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:治疗
  • 分配:随机化
  • 介入模型:交叉作业
  • 屏蔽:双倍的

武器和干预

参与者组/臂
干预/治疗
有源比较器:A Mediterranean style diet
At baseline, participants attended an Educational Group Session (EGS) introducing the principles of the Mediterranean Diet (MD), including recommended foods, foods to limit, cooking methods, and shopping tips. Participants then followed a Mediterranean-style diet for 7 days, replacing typical Western foods with MD alternatives without restricting energy intake. Practical examples and take-home materials with simple food swaps were provided to support adherence.
At baseline, an Educational Group Session (EGS) introduced participants to the Mediterranean Diet (MD) principles to support adherence. The interactive EGS covered MD typical foods to consume and avoid, cooking methods, and practical shopping guidance. Following the EGS, participants adopted a Mediterranean-style diet for a period of 7 days. Participants were encouraged to follow the MD guidelines (replacing typical western foods with MD foods) without restricting energy intake; examples were provided during the EGS and with take-home resource materials which detailed 'simple swaps' or alternative MD food items to replace western food items.
其他名称:
  • 医学博士
安慰剂比较:Habitual diet
Participants were instructed to follow their habitual diet (control) and eating practices for 7 days. without restricting energy intake.
participants were instructed to follow their habitual diet (control) and eating practices for 7 days. without restricting energy intake.

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Mood
大体时间:Baseline and 7 days (final day of each condition) espressed in questionnaire scores
Change in mood measured using the Bond-Lader Visual Analogue Scale (VAS). The scale ranges from 0 to 100, with higher scores indicating a more positive mood state (better outcome).
Baseline and 7 days (final day of each condition) espressed in questionnaire scores

次要结果测量

结果测量
措施说明
大体时间
Wellbeing
大体时间:Baseline and 7 days (final day of each condition) espressed in questionnaire scores
Change in wellbeing measured using the Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS). The WEMWBS total score ranges from 14 to 70, with higher scores indicating greater mental wellbeing (better outcome).
Baseline and 7 days (final day of each condition) espressed in questionnaire scores

其他结果措施

结果测量
措施说明
大体时间
Body weight
大体时间:Baseline and 7 days (final day of each condition) expressed in Kg

Change in body weight, measured in kilograms (kg)

Change in waist circumference, measured in centimetres (cm). Lower waist circumference indicates a better outcome where reduction in central adiposity is a study objective.

Baseline and 7 days (final day of each condition) expressed in Kg
Physical activity
大体时间:Baseline and 7 days (final day of each condition) espressed in questionnaire scores
Change in physical activity measured using the International Physical Activity Questionnaire (IPAQ), expressed as total metabolic equivalent (MET)-minutes per week. Higher scores indicate greater physical activity levels (better outcome). The IPAQ does not have a fixed minimum or maximum score.
Baseline and 7 days (final day of each condition) espressed in questionnaire scores
Dietary intake
大体时间:During the 7 days intervention/condition using DietPlan software
Change in dietary intake assessed using 7-day weighted food records collected during each 7-day intervention period. Dietary intake was quantified as daily energy and nutrient intake. There is no fixed minimum or maximum score; values are reported in their respective units (e.g., kcal/day, g/day). The direction of a better outcome depends on the specific dietary component being evaluated.
During the 7 days intervention/condition using DietPlan software

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Fotini Tsofliou、University of Roehampton

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2019年3月1日

初级完成 (实际的)

2019年5月12日

研究完成 (实际的)

2019年8月20日

研究注册日期

首次提交

2026年6月19日

首先提交符合 QC 标准的

2026年7月15日

首次发布 (实际的)

2026年7月16日

研究记录更新

最后更新发布 (实际的)

2026年7月16日

上次提交的符合 QC 标准的更新

2026年7月15日

最后验证

2026年7月1日

更多信息

与本研究相关的术语

其他研究编号

  • MED-MOOD-UK-2026-001

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

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