Multimodal Decision Support for Perioperative Risk Stratification in Older Adults Undergoing Surgery for Fracture
The goal of this observational study is to establish a standardized multicenter cohort and develop and validate clinically interpretable models for perioperative risk stratification, brain-state risk prediction, objective pain assessment, sleep-pain-delirium association analysis, and longer-term prognosis.The main questions it aims to answer are:
Can clinically interpretable predictive models be developed for perioperative risk stratification and brain-state changes? What are the associations among objective pain measures, sleep quality, and postoperative delirium? Are these perioperative factors associated with longer-term patient outcomes? This is a multicenter cohort study without a separate comparator group. Participants will undergo routine perioperative clinical assessments and standardized follow-up evaluations according to the study protocol.
研究概览
地位
条件
详细说明
研究类型
注册 (估计的)
参与标准
资格标准
适合学习的年龄
- 年长者
接受健康志愿者
取样方法
研究人群
描述
Inclusion Criteria:
- Patients who have hip fracture or another eligible fracture requiring perioperative management and who undergo, or are scheduled to undergo, fracture surgery
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
|---|
|
retrospective records
2,800-3,000 retrospective records
|
|
prospectively enrolled
1,200-1,500 prospectively enrolled participants
|
研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
|---|---|
|
All-cause mortality within 365 days after fracture surgery
大体时间:365 days after fracture surgery
|
365 days after fracture surgery
|
合作者和调查者
研究记录日期
研究主要日期
学习开始 (估计的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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