- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00315666
Prophylactic Effect of Memantine in Chronic Tension-Type Headache
February 19, 2009 updated by: Danish Headache Center
The purpose of this study is to test whether memantine has a prophylactic effect on chronic tension-type headaches.
Study Overview
Study Type
Interventional
Enrollment
40
Phase
- Phase 3
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Glostrup, Denmark, DK-2600
- Danish Headaches Center
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 65 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Chronic tension-type headache
- Normal urine pH
Exclusion Criteria:
- More than 1 migraine attack/month
- Other major illnesses
- Overuse of medicine/alcohol
- Women not using AC
- Pregnant/breast-feeding women
- Allergy to memantine
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: Double
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
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Headache intensity
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Headache duration
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Secondary Outcome Measures
Outcome Measure |
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Side effects
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Headache frequency
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The use of simple analgesics
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Lars Bendtsen, MD, PhD, Danish Headaches Center, Dept. of Neurology, KAS Glostrup, DK-2600 Glostrup
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
May 1, 2006
Primary Completion (Actual)
June 1, 2007
Study Completion (Actual)
June 1, 2007
Study Registration Dates
First Submitted
April 18, 2006
First Submitted That Met QC Criteria
April 18, 2006
First Posted (Estimate)
April 19, 2006
Study Record Updates
Last Update Posted (Estimate)
February 20, 2009
Last Update Submitted That Met QC Criteria
February 19, 2009
Last Verified
February 1, 2009
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
- Brain Diseases
- Central Nervous System Diseases
- Nervous System Diseases
- Pain
- Neurologic Manifestations
- Headache Disorders, Primary
- Headache Disorders
- Headache
- Tension-Type Headache
- Physiological Effects of Drugs
- Neurotransmitter Agents
- Molecular Mechanisms of Pharmacological Action
- Excitatory Amino Acid Antagonists
- Excitatory Amino Acid Agents
- Dopamine Agents
- Antiparkinson Agents
- Anti-Dyskinesia Agents
- Memantine
Other Study ID Numbers
- 2006-000060-82
- KA-20060021
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Tension-Type Headache
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Lucia Trullenque EspallargasNot yet recruitingChronic Tension-Type Headache | Episodic Tension-Type HeadacheSpain
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Grand Valley State UniversityMary Free Bed Rehabilitation HospitalCompletedHeadaches, TensionUnited States
-
Azidus BrasilUnknownTreatment of Episodic Tension HeadacheBrazil
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Riphah International UniversityCompletedTension Type HeadachePakistan
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University of ValenciaCompleted
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GlaxoSmithKlineTerminatedHeadache, Tension-TypeUnited States
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University of ValenciaCompletedTension-type HeadacheSpain
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University of ValenciaCompletedTension-type HeadacheSpain
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University of MinnesotaWithdrawnTension-type HeadacheUnited States
-
University of Colorado, DenverNational Center for Complementary and Integrative Health (NCCIH)CompletedTension-type HeadacheUnited States
Clinical Trials on memantine
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Lyndra Inc.TerminatedHealthy | Gastric RetentionUnited Kingdom
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Chong Kun Dang PharmaceuticalCompletedAlzheimer's Disease (AD)Korea, Republic of
-
HaEmek Medical Center, IsraelUnknown
-
Merz Pharmaceuticals GmbHLLC Merz Pharma, RussiaCompleted
-
Tianjin Medical University Second HospitalRecruiting
-
GeropharmCompletedBioequivalence, AUC, Cmax, PharmacokineticsRussian Federation
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H. Lundbeck A/SCompletedAlzheimer Dementia (AD)China
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University of UtahActive, not recruiting
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University of Kansas Medical CenterUniversity of Missouri-ColumbiaCompletedAmyotrophic Lateral Sclerosis | Frontal Temporal DementiaUnited States
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Kenneth Myers, MDCompleted